AU2001278496A1 - Zinc finger domain recognition code and uses thereof - Google Patents
Zinc finger domain recognition code and uses thereofInfo
- Publication number
- AU2001278496A1 AU2001278496A1 AU2001278496A AU7849601A AU2001278496A1 AU 2001278496 A1 AU2001278496 A1 AU 2001278496A1 AU 2001278496 A AU2001278496 A AU 2001278496A AU 7849601 A AU7849601 A AU 7849601A AU 2001278496 A1 AU2001278496 A1 AU 2001278496A1
- Authority
- AU
- Australia
- Prior art keywords
- base
- zfp
- zinc finger
- nucleic acid
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22006000P | 2000-07-21 | 2000-07-21 | |
| US60220060 | 2000-07-21 | ||
| PCT/EP2001/008367 WO2002008286A2 (fr) | 2000-07-21 | 2001-07-19 | Code de reconnaissance pour domaines en doigt de zinc et ses utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001278496A1 true AU2001278496A1 (en) | 2002-02-05 |
Family
ID=22821881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001278496A Abandoned AU2001278496A1 (en) | 2000-07-21 | 2001-07-19 | Zinc finger domain recognition code and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20040091878A1 (fr) |
| EP (1) | EP1303608A2 (fr) |
| JP (1) | JP2004519211A (fr) |
| AR (1) | AR034129A1 (fr) |
| AU (1) | AU2001278496A1 (fr) |
| CA (1) | CA2416664A1 (fr) |
| IL (1) | IL154059A0 (fr) |
| WO (1) | WO2002008286A2 (fr) |
| ZA (1) | ZA200300651B (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113439121A (zh) * | 2019-02-13 | 2021-09-24 | 普罗拜奥根股份公司 | 具有增强的插入位点选择特性的转座酶 |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002057308A2 (fr) * | 2001-01-22 | 2002-07-25 | Sangamo Biosciences, Inc. | Polypeptides se liant a un acide nucleique |
| ATE494370T1 (de) * | 2002-07-24 | 2011-01-15 | Manoa Biosciences Inc | Vektoren auf transposonbasis und verfahren zur integration von nukleinsäuren |
| JP2006518204A (ja) | 2003-02-10 | 2006-08-10 | マックス−デルブルック−セントラム フユール モレクラーレ メディツィン(エムディーシー) | トランスポゾンに基づく標的化システム |
| DK1594972T3 (da) * | 2003-02-10 | 2011-04-18 | Max Delbrueck Centrum | Transposon-baseret målretningssystem |
| US20060236413A1 (en) * | 2003-02-10 | 2006-10-19 | Zoltan Ivics | Transposon-based targeting system |
| KR20060054196A (ko) * | 2003-06-10 | 2006-05-22 | 주식회사 툴젠 | 전달가능한 dna-결합 단백질 |
| EP2418281B1 (fr) * | 2003-10-24 | 2016-06-01 | Gencia Corporation | Procédés et compositions pour l'administration de polynucléotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| US8507277B2 (en) * | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| US20090123468A1 (en) * | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US20090208478A1 (en) * | 2003-10-24 | 2009-08-20 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| US8133733B2 (en) * | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| GB0328448D0 (en) * | 2003-12-09 | 2004-01-14 | Univ Leeds | Agents for the regulation of transcription via zinc finger proteins |
| EP1707575A1 (fr) * | 2005-04-01 | 2006-10-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Ligation des peptides en doigt à zinc synthétiques au protéines pour détecter l'ADN double brin (sondes en doigt à zinc) |
| JP2009506025A (ja) * | 2005-08-26 | 2009-02-12 | 国立大学法人京都大学 | 抗ウイルス剤及びウイルス複製阻害剤 |
| WO2007102618A1 (fr) * | 2006-03-08 | 2007-09-13 | Kyoto University | Agent de coupure d'acide nucléique |
| GB0607063D0 (en) * | 2006-04-07 | 2006-05-17 | Cellcentric Ltd | Compositions and methods for epigenetic modification of nucleic acid sequences in vivo |
| US7977535B2 (en) | 2006-07-12 | 2011-07-12 | Board Of Trustees Of Michigan State University | DNA encoding ring zinc-finger protein and the use of the DNA in vectors and bacteria and in plants |
| CA2937438C (fr) | 2007-09-27 | 2020-07-07 | Dow Agrosciences Llc | Proteines a doigt de zinc synthetisees ciblant des genes de 5-enolpyruvyl shikimate-3-phosphate synthase |
| US20100316702A1 (en) * | 2008-01-08 | 2010-12-16 | The Regents Of The University Of California | Compositions and methods for regulating erythropoeitin expression and ameliorating anemia and stimulating erythropoiesis |
| USRE50635E1 (en) | 2008-04-30 | 2025-10-14 | Sanbio, Inc. | Neural regenerating cells with alterations in DNA methylation |
| EP2130836B1 (fr) * | 2008-06-03 | 2013-02-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Supports et procédés de production de doigts de zinc et ses concatémères |
| EP2461819A4 (fr) | 2009-07-28 | 2013-07-31 | Sangamo Biosciences Inc | Procédés et compositions de traitement de troubles de répétition tri-nucléotidique |
| CN108148120A (zh) * | 2010-06-07 | 2018-06-12 | 世良贵史 | 双生病毒复制抑制剂 |
| US9746475B2 (en) | 2011-03-14 | 2017-08-29 | University Of Southern California | Antibody and antibody mimetic for visualization and ablation of endogenous proteins |
| IL277027B (en) | 2011-09-21 | 2022-07-01 | Sangamo Therapeutics Inc | Methods and compositions for regulation of transgene expression |
| JP2015013810A (ja) * | 2011-10-27 | 2015-01-22 | 貴史 世良 | ジェミニウイルス複製阻害剤 |
| US10689643B2 (en) | 2011-11-22 | 2020-06-23 | Active Motif, Inc. | Targeted transposition for use in epigenetic studies |
| CN108285491B (zh) | 2012-02-29 | 2021-08-10 | 桑格摩生物科学股份有限公司 | 治疗亨廷顿氏病的方法和组合物 |
| US9890364B2 (en) * | 2012-05-29 | 2018-02-13 | The General Hospital Corporation | TAL-Tet1 fusion proteins and methods of use thereof |
| DK3041498T3 (da) * | 2013-09-05 | 2022-05-09 | Massachusetts Inst Technology | Afstemning af mikrobielle populationer med programmerbare nukleaser |
| CN105934524A (zh) | 2013-11-11 | 2016-09-07 | 桑格摩生物科学股份有限公司 | 用于治疗亨廷顿氏病的方法和组合物 |
| US20220409745A1 (en) * | 2019-11-19 | 2022-12-29 | The Regents Of The University Of California | Compositions and methods of using engineered fusion proteins that bind g4c2 human repeats |
| CN113368253B (zh) * | 2020-03-10 | 2022-06-10 | 中国科学院宁波工业技术研究院慈溪生物医学工程研究所 | 基于沸石咪唑框架结构的药物载体及其制备方法与应用 |
| WO2024026232A1 (fr) * | 2022-07-27 | 2024-02-01 | Pioneer Hi-Bred International, Inc | Édition de génome piégée par arn guide |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763209A (en) * | 1988-09-26 | 1998-06-09 | Arch Development Corporation | Methods and materials relating to the functional domains of DNA binding proteins |
| EP0475779A1 (fr) * | 1990-09-14 | 1992-03-18 | Vittal Mallya Scientific Research Foundation | Procédé pour la séparation de protéines, polypetides ou métaux par utilisation de phosvitine immobilisée, éventuellement modifiée |
| EP0564592B1 (fr) * | 1990-12-21 | 1999-10-13 | The Rockefeller University | Facteur de transcription enrichi par extraits hepatiques |
| US5916794A (en) * | 1992-04-03 | 1999-06-29 | Johns Hopkins University | Methods for inactivating target DNA and for detecting conformational change in a nucleic acid |
| US5436150A (en) * | 1992-04-03 | 1995-07-25 | The Johns Hopkins University | Functional domains in flavobacterium okeanokoities (foki) restriction endonuclease |
| US5792640A (en) * | 1992-04-03 | 1998-08-11 | The Johns Hopkins University | General method to clone hybrid restriction endonucleases using lig gene |
| US6107059A (en) * | 1992-04-29 | 2000-08-22 | Affymax Technologies N.V. | Peptide library and screening method |
| AU684524B2 (en) * | 1993-06-14 | 1997-12-18 | Tet Systems Holding Gmbh & Co. Kg | Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters |
| AU704601B2 (en) * | 1994-01-18 | 1999-04-29 | Scripps Research Institute, The | Zinc finger protein derivatives and methods therefor |
| US6140466A (en) * | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| US5837692A (en) * | 1994-04-07 | 1998-11-17 | Mercola; Dan | Inhibition of the mitogenic activity of PDGF by mammalian EGr |
| US5972643A (en) * | 1994-06-17 | 1999-10-26 | Fred Hutchinson Cancer Research Center | Isolated polynucleotide molecules encoding CTCF, a CCCTC-binding factor |
| US5831008A (en) * | 1994-08-18 | 1998-11-03 | La Jolla Cancer Research Foundation | Retinoblastoma protein-interacting zinc finger proteins |
| EP2022856B1 (fr) * | 1994-08-20 | 2011-09-14 | Gendaq Limited | Améliorations de ou associées aux protéines de liaison pour la reconnaissance de l'ADN |
| GB9824544D0 (en) * | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| US6008190A (en) * | 1994-12-15 | 1999-12-28 | California Institute Of Technology | Cobalt Schiff base compounds |
| US5789538A (en) * | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US6090783A (en) * | 1995-03-24 | 2000-07-18 | Shionogi & Co., Ltd. | DNA molecule relating to suppression of gene expression and novel protein |
| US6218522B1 (en) * | 1996-03-19 | 2001-04-17 | Shionogi & Co., Ltd. | DNA molecule relating to suppression of gene expression and novel protein |
| US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
| CA2224626C (fr) * | 1995-06-23 | 2011-11-01 | Leendert Hendrik De Graaf | Systeme d'expression utilisant un activateur transcriptionnel xylanolytique |
| US6017734A (en) * | 1995-07-07 | 2000-01-25 | The Texas A & M University System | Unique nucleotide and amino acid sequence and uses thereof |
| US5770720A (en) * | 1995-08-30 | 1998-06-23 | Barnes-Jewish Hospital | Ubiquitin conjugating enzymes having transcriptional repressor activity |
| US5981217A (en) * | 1995-12-11 | 1999-11-09 | Mayo Foundation For Medical Education And Research | DNA encoding TGF-β inducible early factor-1 (TIEF-1), a gene expressed by osteoblasts |
| US5905146A (en) * | 1996-03-15 | 1999-05-18 | University Of Arkansas | DNA binding protein S1-3 |
| US5928955A (en) * | 1996-03-22 | 1999-07-27 | California Institute Of Technology | Peptidyl fluorescent chemosensor for divalent zinc |
| US5928941A (en) * | 1996-10-07 | 1999-07-27 | President And Fellows Of Harvard College | Repressor kruppel-like factor |
| US5869250A (en) * | 1996-12-02 | 1999-02-09 | The University Of North Carolina At Chapel Hill | Method for the identification of peptides that recognize specific DNA sequences |
| US6235538B1 (en) * | 1997-03-05 | 2001-05-22 | The Board Of Regents Of The University Of Oklahoma | Test for detecting substances which alter the conformational structure of zinc fingers |
| GB9710807D0 (en) * | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710809D0 (en) * | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| JP2003524368A (ja) * | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、dna結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
| US6153383A (en) * | 1997-12-09 | 2000-11-28 | Verdine; Gregory L. | Synthetic transcriptional modulators and uses thereof |
| US6410248B1 (en) * | 1998-01-30 | 2002-06-25 | Massachusetts Institute Of Technology | General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites |
| AU758728B2 (en) * | 1998-02-20 | 2003-03-27 | Genome Dynamics, Inc. | Method for designing DNA-binding proteins of the zinc-finger class |
| WO1999047656A2 (fr) * | 1998-03-17 | 1999-09-23 | Gendaq Limited | Proteines de fixation a l'acide nucleique |
| US6100035A (en) * | 1998-07-14 | 2000-08-08 | Cistem Molecular Corporation | Method of identifying cis acting nucleic acid elements |
| US6140081A (en) * | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US6534261B1 (en) * | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) * | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| AU2001252428A1 (en) * | 2000-05-08 | 2001-11-20 | Gendaq Limited | Nucleic acid binding polypeptides |
-
2001
- 2001-07-19 CA CA002416664A patent/CA2416664A1/fr not_active Abandoned
- 2001-07-19 AU AU2001278496A patent/AU2001278496A1/en not_active Abandoned
- 2001-07-19 WO PCT/EP2001/008367 patent/WO2002008286A2/fr not_active Ceased
- 2001-07-19 IL IL15405901A patent/IL154059A0/xx unknown
- 2001-07-19 JP JP2002514190A patent/JP2004519211A/ja active Pending
- 2001-07-19 US US10/333,487 patent/US20040091878A1/en not_active Abandoned
- 2001-07-19 EP EP01956547A patent/EP1303608A2/fr not_active Withdrawn
- 2001-07-20 AR ARP010103462A patent/AR034129A1/es not_active Application Discontinuation
- 2001-07-23 US US09/911,261 patent/US20030134350A1/en not_active Abandoned
-
2003
- 2003-01-02 ZA ZA200300651A patent/ZA200300651B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113439121A (zh) * | 2019-02-13 | 2021-09-24 | 普罗拜奥根股份公司 | 具有增强的插入位点选择特性的转座酶 |
Also Published As
| Publication number | Publication date |
|---|---|
| AR034129A1 (es) | 2004-02-04 |
| US20040091878A1 (en) | 2004-05-13 |
| JP2004519211A (ja) | 2004-07-02 |
| WO2002008286A2 (fr) | 2002-01-31 |
| ZA200300651B (en) | 2003-11-11 |
| US20030134350A1 (en) | 2003-07-17 |
| CA2416664A1 (fr) | 2002-01-31 |
| WO2002008286A3 (fr) | 2002-07-11 |
| EP1303608A2 (fr) | 2003-04-23 |
| IL154059A0 (en) | 2003-07-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2001278496A1 (en) | Zinc finger domain recognition code and uses thereof | |
| US20030082561A1 (en) | Zinc finger domain recognition code and uses thereof | |
| US7151201B2 (en) | Methods and compositions to modulate expression in plants | |
| DK2205749T3 (en) | MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes | |
| CA2396898A1 (fr) | Procedes et compositions permettant de moduler l'expression de genes vegetaux | |
| AU2003212816B2 (en) | Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression | |
| AU2006203634B2 (en) | Methods and compositions to modulate expression in plants | |
| AU2003212816A1 (en) | Nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression | |
| AU2008201951B2 (en) | Composition comprising nuclear-envelope and nuclear-lamina binding chimeras for modulating gene expression |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |