AU2001271785A1 - Combinations of statins, estrogenic agents and optionally estrogens - Google Patents
Combinations of statins, estrogenic agents and optionally estrogensInfo
- Publication number
- AU2001271785A1 AU2001271785A1 AU2001271785A AU7178501A AU2001271785A1 AU 2001271785 A1 AU2001271785 A1 AU 2001271785A1 AU 2001271785 A AU2001271785 A AU 2001271785A AU 7178501 A AU7178501 A AU 7178501A AU 2001271785 A1 AU2001271785 A1 AU 2001271785A1
- Authority
- AU
- Australia
- Prior art keywords
- statins
- combinations
- estrogenic agents
- estrogens
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000000262 estrogen Substances 0.000 title 2
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
- 229940011871 estrogen Drugs 0.000 title 1
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21609600P | 2000-07-06 | 2000-07-06 | |
| US21618400P | 2000-07-06 | 2000-07-06 | |
| US60/216,096 | 2000-07-06 | ||
| US60/216,184 | 2000-07-06 | ||
| PCT/US2001/021085 WO2002003977A2 (en) | 2000-07-06 | 2001-06-29 | Combinations of statins, estrogenic agents and optionally estrogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2001271785A1 true AU2001271785A1 (en) | 2002-01-21 |
Family
ID=26910656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2001271785A Abandoned AU2001271785A1 (en) | 2000-07-06 | 2001-06-29 | Combinations of statins, estrogenic agents and optionally estrogens |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1359940A2 (en) |
| JP (1) | JP2004502731A (en) |
| CN (1) | CN1468110A (en) |
| AU (1) | AU2001271785A1 (en) |
| BR (1) | BR0112365A (en) |
| CA (1) | CA2414060A1 (en) |
| MX (1) | MXPA02012896A (en) |
| WO (1) | WO2002003977A2 (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8668914B2 (en) | 2002-07-24 | 2014-03-11 | Brigham Young University | Use of equol for treating skin diseases |
| BR0313182A (en) | 2002-07-24 | 2007-07-24 | Childrens Hosp Medical Center | enantiomeric equol containing compositions and products |
| US8580846B2 (en) | 2002-10-29 | 2013-11-12 | Brigham Young University | Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders |
| CA2504682A1 (en) | 2002-10-29 | 2004-05-13 | Colorado State University Research Foundation | Use of equol for treating androgen mediated diseases |
| US7781478B2 (en) | 2004-07-14 | 2010-08-24 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
| CN113248494A (en) | 2015-10-01 | 2021-08-13 | 奥列马制药公司 | tetrahydro-1H-pyridine [3,4-b ] indole antiestrogens |
| US20170166551A1 (en) | 2015-12-09 | 2017-06-15 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective estrogen receptor downregulator compounds |
| WO2017197046A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | C3-carbon linked glutarimide degronimers for target protein degradation |
| EP3455219A4 (en) | 2016-05-10 | 2019-12-18 | C4 Therapeutics, Inc. | AMINE-LINKED C3-GLUTARIMIDE DEGRONIMERS FOR THE DEGRADATION OF TARGET PROTEINS |
| ES2989988T3 (en) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Heterocyclic degronimers for the degradation of target proteins |
| ES2990061T3 (en) | 2016-05-10 | 2024-11-28 | C4 Therapeutics Inc | Spirocyclic degronimers for the degradation of target proteins |
| BR112018077136A2 (en) | 2016-07-01 | 2019-04-30 | G1 Therapeutics, Inc. | compound, and methods for treating a disorder associated with abnormal cell proliferation and for reducing the effect of chemotherapy on healthy cells. |
| WO2018081168A2 (en) | 2016-10-24 | 2018-05-03 | The Board Of Trustees Of The University Of Illinois | Benzothiophene-based selective mixed estrogen receptor downregulators |
| MX2019008158A (en) | 2017-01-06 | 2019-12-09 | G1 Therapeutics Inc | Combination therapy for the treatment of cancer. |
| KR20190117582A (en) | 2017-02-10 | 2019-10-16 | 쥐원 쎄라퓨틱스, 인크. | Benzothiophene Estrogen Receptor Modulator |
| WO2018237026A1 (en) | 2017-06-20 | 2018-12-27 | C4 Therapeutics, Inc. | N / O-LINKED DEGRONS AND DEGRONIMERS FOR DEGRADATION OF PROTEINS |
| CA3067873A1 (en) | 2017-06-29 | 2019-01-03 | G1 Therapeutics, Inc. | Morphic forms of g1t38 and methods of manufacture thereof |
| EP3897631A4 (en) | 2018-12-20 | 2022-11-23 | C4 Therapeutics, Inc. | TARGETED PROTEIN DEGRADATION |
| AU2020311337A1 (en) | 2019-07-07 | 2022-01-20 | Olema Pharmaceuticals, Inc. | Regimens of estrogen receptor antagonists |
| WO2021127561A1 (en) | 2019-12-20 | 2021-06-24 | C4 Therapeutics, Inc. | Isoindolinone and indazole compounds for the degradation of egfr |
| KR20220166797A (en) | 2020-03-05 | 2022-12-19 | 씨4 테라퓨틱스, 인코포레이티드 | Compounds for targeted degradation of BRD9 |
| JP2023538517A (en) | 2020-08-05 | 2023-09-08 | シーフォー セラピューティクス, インコーポレイテッド | Compounds for targeted degradation of RET |
| TW202313628A (en) | 2021-06-08 | 2023-04-01 | 美商C4醫藥公司 | Therapeutics for the degradation of mutant braf |
| KR20250055538A (en) | 2022-08-03 | 2025-04-24 | 브리스톨-마이어스 스큅 컴퍼니 | Compounds for modulating RET proteins |
| EP4611900A1 (en) | 2022-11-04 | 2025-09-10 | Bristol-Myers Squibb Company | Ret-ldd protein inhibitors |
| CN120569388A (en) | 2022-11-04 | 2025-08-29 | 百时美施贵宝公司 | RET-LDD protein degradation agent |
| WO2025006753A2 (en) | 2023-06-30 | 2025-01-02 | Merck Patent Gmbh | Heterobifunctional compounds for the degradation of kras protein |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL194750B1 (en) * | 1998-05-15 | 2007-06-29 | Wyeth Corp | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole in combination with estrogens |
| CA2331318A1 (en) * | 1998-05-15 | 1999-11-25 | James Harrison Pickar | Compositions comprising 2-phenyl-indole compounds and estrogen formulations |
-
2001
- 2001-06-29 WO PCT/US2001/021085 patent/WO2002003977A2/en not_active Ceased
- 2001-06-29 CN CNA018150896A patent/CN1468110A/en active Pending
- 2001-06-29 MX MXPA02012896A patent/MXPA02012896A/en unknown
- 2001-06-29 BR BR0112365-3A patent/BR0112365A/en not_active IP Right Cessation
- 2001-06-29 CA CA002414060A patent/CA2414060A1/en not_active Abandoned
- 2001-06-29 AU AU2001271785A patent/AU2001271785A1/en not_active Abandoned
- 2001-06-29 JP JP2002508432A patent/JP2004502731A/en active Pending
- 2001-06-29 EP EP01950826A patent/EP1359940A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004502731A (en) | 2004-01-29 |
| WO2002003977A3 (en) | 2003-09-04 |
| CA2414060A1 (en) | 2002-01-17 |
| CN1468110A (en) | 2004-01-14 |
| WO2002003977A2 (en) | 2002-01-17 |
| MXPA02012896A (en) | 2003-10-24 |
| BR0112365A (en) | 2003-05-13 |
| EP1359940A2 (en) | 2003-11-12 |
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