[go: up one dir, main page]

MXPA02012896A - Combinations of statins, estrogenic agents and optionally estrogens. - Google Patents

Combinations of statins, estrogenic agents and optionally estrogens.

Info

Publication number
MXPA02012896A
MXPA02012896A MXPA02012896A MXPA02012896A MXPA02012896A MX PA02012896 A MXPA02012896 A MX PA02012896A MX PA02012896 A MXPA02012896 A MX PA02012896A MX PA02012896 A MXPA02012896 A MX PA02012896A MX PA02012896 A MXPA02012896 A MX PA02012896A
Authority
MX
Mexico
Prior art keywords
statins
combinations
estrogenic agents
estrogens
optionally
Prior art date
Application number
MXPA02012896A
Other languages
Spanish (es)
Inventor
Christopher Paul Miller
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA02012896A publication Critical patent/MXPA02012896A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
MXPA02012896A 2000-07-06 2001-06-29 Combinations of statins, estrogenic agents and optionally estrogens. MXPA02012896A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21618400P 2000-07-06 2000-07-06
US21609600P 2000-07-06 2000-07-06
PCT/US2001/021085 WO2002003977A2 (en) 2000-07-06 2001-06-29 Combinations of statins, estrogenic agents and optionally estrogens

Publications (1)

Publication Number Publication Date
MXPA02012896A true MXPA02012896A (en) 2003-10-24

Family

ID=26910656

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02012896A MXPA02012896A (en) 2000-07-06 2001-06-29 Combinations of statins, estrogenic agents and optionally estrogens.

Country Status (8)

Country Link
EP (1) EP1359940A2 (en)
JP (1) JP2004502731A (en)
CN (1) CN1468110A (en)
AU (1) AU2001271785A1 (en)
BR (1) BR0112365A (en)
CA (1) CA2414060A1 (en)
MX (1) MXPA02012896A (en)
WO (1) WO2002003977A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8668914B2 (en) 2002-07-24 2014-03-11 Brigham Young University Use of equol for treating skin diseases
US7396855B2 (en) 2002-07-24 2008-07-08 Children's Hospital Medical Center Compositions and products containing S-equol, and methods for their making
US8580846B2 (en) 2002-10-29 2013-11-12 Brigham Young University Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders
CA2504682A1 (en) 2002-10-29 2004-05-13 Colorado State University Research Foundation Use of equol for treating androgen mediated diseases
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
LT3355884T (en) 2015-10-01 2021-07-26 Olema Pharmaceuticals, Inc. Tetrahydro-1h-pyrido[3,4-b]indole anti-estrogenic drugs
CA3008020C (en) 2015-12-09 2024-02-20 The Board Of Trustees Of The University Of Illinois Benzothiophene-based selective estrogen receptor downregulators
WO2017197055A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Heterocyclic degronimers for target protein degradation
WO2017197051A1 (en) 2016-05-10 2017-11-16 C4 Therapeutics, Inc. Amine-linked c3-glutarimide degronimers for target protein degradation
EP3454862B1 (en) 2016-05-10 2024-09-11 C4 Therapeutics, Inc. Spirocyclic degronimers for target protein degradation
CN109641874A (en) 2016-05-10 2019-04-16 C4医药公司 C for target protein degradation3The glutarimide degron body of carbon connection
BR112018077136A2 (en) 2016-07-01 2019-04-30 G1 Therapeutics, Inc. compound, and methods for treating a disorder associated with abnormal cell proliferation and for reducing the effect of chemotherapy on healthy cells.
WO2018081168A2 (en) 2016-10-24 2018-05-03 The Board Of Trustees Of The University Of Illinois Benzothiophene-based selective mixed estrogen receptor downregulators
IL267795B2 (en) 2017-01-06 2023-02-01 G1 Therapeutics Inc Combined treatment for cancer
CA3052810A1 (en) 2017-02-10 2018-08-16 G1 Therapeutics, Inc. Benzothiophene estrogen receptor modulators
EP3641762B1 (en) 2017-06-20 2026-02-18 C4 Therapeutics, Inc. N/o-linked degrons and degronimers for protein degradation
EA201992768A1 (en) 2017-06-29 2020-05-19 Г1 Терапьютикс, Инк. MORPHOLOGICAL FORMS G1T38 AND METHODS FOR PRODUCING THEM
WO2020132561A1 (en) 2018-12-20 2020-06-25 C4 Therapeutics, Inc. Targeted protein degradation
KR20220034129A (en) 2019-07-07 2022-03-17 올레마 파마슈티컬스 인코포레이티드 Estrogen receptor antagonist therapy
JP7757284B2 (en) 2019-12-20 2025-10-21 シーフォー セラピューティクス, インコーポレイテッド Isoindolinone and indazole compounds for degradation of EGFR
BR112022017393A2 (en) 2020-03-05 2022-10-18 C4 Therapeutics Inc COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD TO TREAT A BRD9-mediated DISORDER, AND, USE OF A COMPOUND
CA3188313A1 (en) 2020-08-05 2022-02-10 C4 Therapeutics, Inc. Compounds for targeted degradation of ret
CA3174245A1 (en) 2021-06-08 2022-12-15 Christopher G. Nasveschuk Therapeutics for the degradation of mutant braf
EP4565585A1 (en) 2022-08-03 2025-06-11 Bristol-Myers Squibb Company Compounds for modulating ret protein
EP4611900A1 (en) 2022-11-04 2025-09-10 Bristol-Myers Squibb Company Ret-ldd protein inhibitors
WO2024097989A1 (en) 2022-11-04 2024-05-10 Bristol-Myers Squibb Company Ret-ldd protein degraders
AU2024310341A1 (en) 2023-06-30 2026-02-12 Merck Patent Gmbh Heterobifunctional compounds for the degradation of kras protein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002515484A (en) * 1998-05-15 2002-05-28 アメリカン・ホーム・プロダクツ・コーポレイション Composition comprising 2-phenylindole compound and estrogen preparation
UA66861C2 (en) * 1998-05-15 2004-06-15 Уайт 2-phenyl-1-[4-(2-aminoeihoxy)benzyl]-indole in combination with estrogens, method for treatment and pharmaceutical product

Also Published As

Publication number Publication date
WO2002003977A2 (en) 2002-01-17
CN1468110A (en) 2004-01-14
JP2004502731A (en) 2004-01-29
CA2414060A1 (en) 2002-01-17
WO2002003977A3 (en) 2003-09-04
EP1359940A2 (en) 2003-11-12
BR0112365A (en) 2003-05-13
AU2001271785A1 (en) 2002-01-21

Similar Documents

Publication Publication Date Title
MXPA02012896A (en) Combinations of statins, estrogenic agents and optionally estrogens.
MXPA02012897A (en) Combinations of bisphosphonates, estrogenic agents and optionally estrogens.
AU5208401A (en) 3-nitrogen-6,7-dioxygen steroids and uses related thereto
MXPA02012891A (en) Pharmaceutical compositions of estrogenic agents.
MXPA03000499A (en) Wireless electrocardiograph system and method.
ZA200203316B (en) New use and novel n-azabicyclo-amide derivatives.
MXPA03005445A (en) I2.
ZA200204165B (en) Fulvestrant formulation.
MXPA03002410A (en) 4-amino-quinazolines.
MXPA03001983A (en) Exemestane as chemopreventing agent.
ZA200207489B (en) Apomorphine derivatives and methods for their use.
EG23373A (en) Process and intermediates.
MXPA03003522A (en) Diaper.
EG23262A (en) Delta -pyrrolines.
ZA200302014B (en) Methods and compositions for promoting the maturation of monocytes.
MXPA03001591A (en) 10-aryl-11-h.
IL144455A0 (en) 16-hydroxyestratrienes as selective estrogens
MXPA03001877A (en) 2-guanidino-4-aryl-quinazoline.
MXPA03002668A (en) Sulfonylguanidine.
MXPA03005714A (en) Sulfamidothienopyrimidines.
MXPA03002411A (en) 4-amino-quinazolines.
MXPA03005494A (en) Benzoylpyridazines.
MXPA03002521A (en) Triazolo-epothilones.
MXPA01000464A (en) Composition.
ZA200300417B (en) 16alpha-methyl or ethyl substituted estrogens.