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AU2001269836A1 - Proteases - Google Patents

Proteases

Info

Publication number
AU2001269836A1
AU2001269836A1 AU2001269836A AU6983601A AU2001269836A1 AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1 AU 2001269836 A AU2001269836 A AU 2001269836A AU 6983601 A AU6983601 A AU 6983601A AU 2001269836 A1 AU2001269836 A1 AU 2001269836A1
Authority
AU
Australia
Prior art keywords
proteases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001269836A
Inventor
Chandra S. Arvizu
Janice Au-Young
Yalda Azimzai
Mariah R. Baughn
Narinder K. Chawla
Debopriya Das
Angelo M Delegeane
Vicki S. Elliott
Ameena R. Gandhi
April Hafalia
Deborah A. Kallick
Liam Kearney
Farrah A. Khan
Preeti Lal
Ernestine A. Lee
Dyung Aina M. Lu
Yan Lu
Danniel B. Nguyen
Jayalaxmi Ramkumar
Roopa Reddy
Y. Tom Tang
Catherine M. Tribouley
Roderick T. Walsh
Yuming Xu
Monique G. Yao
Henry Yue
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of AU2001269836A1 publication Critical patent/AU2001269836A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2001269836A 2000-06-16 2001-06-13 Proteases Abandoned AU2001269836A1 (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US21233600P 2000-06-16 2000-06-16
US60/212,336 2000-06-16
US21395500P 2000-06-22 2000-06-22
US60/213,955 2000-06-22
US21539600P 2000-06-29 2000-06-29
US60/215,396 2000-06-29
US21682100P 2000-07-07 2000-07-07
US60/216,821 2000-07-07
US21894600P 2000-07-14 2000-07-14
US60/218,946 2000-07-14
PCT/US2001/019178 WO2001098468A2 (en) 2000-06-16 2001-06-13 Proteases

Publications (1)

Publication Number Publication Date
AU2001269836A1 true AU2001269836A1 (en) 2002-01-02

Family

ID=27539651

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001269836A Abandoned AU2001269836A1 (en) 2000-06-16 2001-06-13 Proteases

Country Status (5)

Country Link
EP (1) EP1292684A2 (en)
JP (1) JP2004515217A (en)
AU (1) AU2001269836A1 (en)
CA (1) CA2411971A1 (en)
WO (1) WO2001098468A2 (en)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001518290A (en) 1997-09-29 2001-10-16 ポイント セラピューティクス， インコーポレイテッド Stimulation of hematopoietic cells in vitro
US6979697B1 (en) 1998-08-21 2005-12-27 Point Therapeutics, Inc. Regulation of substrate activity
US20030096391A1 (en) * 2000-12-22 2003-05-22 Millennium Pharmaceuticals, Inc. 17903, a novel human aminopeptidase and uses therefor
DE60043783D1 (en) * 1999-11-11 2010-03-18 Astellas Pharma Inc METALOPROTEASE WITH AGGRECANASE ACTIVITY
US7700341B2 (en) 2000-02-03 2010-04-20 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
WO2001079473A2 (en) * 2000-04-18 2001-10-25 Millennium Pharmaceuticals, Inc. 21953, a human prolyl oligopeptidase family member and uses thereof
US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
EP1294901A2 (en) * 2000-05-04 2003-03-26 Sugen, Inc. Novel proteases
ATE317399T1 (en) * 2000-06-23 2006-02-15 REGULATION OF HUMAN PROSTASIN-LIKE SERINE PROTEASE
US20040132023A1 (en) 2000-06-26 2004-07-08 Shyam Ramakrishnan Regulation of human caspase-1-like protease
US20020137181A1 (en) * 2000-07-18 2002-09-26 Rachel Meyers 14087, a novel serine protease molecule and uses therefor
AU2001293718A1 (en) * 2000-08-07 2002-02-18 Bayer Aktiengesellschaft Regulation of human membrane-type serine protease
GB0020345D0 (en) * 2000-08-17 2000-10-04 Glaxo Group Ltd Protein
JP2004531201A (en) * 2000-08-22 2004-10-14 レキシコン・ジェネティクス・インコーポレーテッド Novel human protease and polynucleotide encoding the protease
WO2002026949A2 (en) * 2000-09-29 2002-04-04 Lexicon Genetics Incorporated Human proteases and polynucleotides encoding the same
KR100875221B1 (en) * 2000-10-12 2008-12-19 페링 비.브이 Novel Serine Protease Gene Related to Dipipipo
WO2002051995A1 (en) * 2000-12-22 2002-07-04 Millennium Pharmaceuticals, Inc. A human metallo protease member of the adamts family, and uses thereof
GB0101760D0 (en) * 2001-01-23 2001-03-07 Glaxo Group Ltd Novel protein
WO2002072786A2 (en) 2001-03-13 2002-09-19 Corvas International, Inc. Nucleic acid molecules encoding a transmembrane serine protease 7, the encoded polypeptides and methods based thereon
US7172892B2 (en) * 2001-03-22 2007-02-06 Dendreon Corporation Nucleic acid molecules encoding serine protease CVSP14, the encoded polypeptides and methods based thereon
US7034134B2 (en) 2001-04-26 2006-04-25 Bristol-Myers Squibb Company Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29
US7112430B2 (en) * 2001-05-14 2006-09-26 Dendreon Corporation Nucleic acid molecules encoding a transmembrane serine protease 10, the encoded polypeptides and methods based thereon
AU2002319703A1 (en) 2001-07-27 2003-02-17 Wyeth Aggrecanase molecules
WO2003027282A1 (en) * 2001-09-24 2003-04-03 Daiichi Fine Chemical Co., Ltd. Adamts-15, -16, -17, -18 and -19
AU2002351945A1 (en) * 2001-11-13 2003-05-26 Universite De Liege A new disintegrin and metalloproteinase with thrombospondin type i repeats polynucleotide and its encoded polypeptide
AU2003238359A1 (en) * 2002-01-28 2003-09-02 Bayer Aktiengesellschaft Regulation of human membrane-type serine protease
EP2341350B1 (en) * 2003-09-20 2017-11-08 Electrophoretics Limited Diagnostic method for brain damage-related disorders based on detection of dj-1
US20080248462A1 (en) * 2003-10-21 2008-10-09 Baayer Healhcare Ag Diagnostics and Therapeutics for Diseases Associated with Arginyl Aminopeptidase (Aminopeptidase B)-Like 1 (Rnpepl1)
WO2005106021A1 (en) * 2004-04-28 2005-11-10 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with dipeptidyl-peptidase 8 (dpp8)
EP1751182A1 (en) * 2004-05-27 2007-02-14 VIB vzw A novel human card-only protein that inhibits pro-il-1 beta; maturation
EP3231442B1 (en) * 2006-06-23 2019-12-25 ADC Therapeutics SA Polynucleotides and polypeptide sequences involved in cancer
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
EP2083861A4 (en) 2006-11-07 2010-11-24 Merck Sharp & Dohme Antagonists of pcsk9
WO2008118386A2 (en) 2007-03-27 2008-10-02 Merck & Co., Inc. Method for detecting autoprocessed, secreted pcsk9
JOP20080381B1 (en) 2007-08-23 2023-03-28 Amgen Inc Antigen Binding Proteins to Proprotein Convertase subtillisin Kexin type 9 (pcsk9)
AR070315A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc ANTIBODIES 1B20 ANTAGONISTS OF PCSK9
AR070316A1 (en) 2008-02-07 2010-03-31 Merck & Co Inc PCSK9 ANTAGONISTS (SUBTILISINE-KEXINA TYPE 9 PROPROTEIN)
EP3130674B1 (en) 2008-11-03 2020-07-08 ADC Therapeutics SA Antibodies that specifically block the biological activity of a tumor antigen
WO2010068526A1 (en) 2008-12-12 2010-06-17 Merck Sharp & Dohme Corp. Pcsk9 immunoassay
AU2010313324A1 (en) 2009-10-30 2012-04-12 Merck Sharp & Dohme Corp. AX213 and AX132 PCSK9 antagonists and variants
WO2011053759A1 (en) 2009-10-30 2011-05-05 Merck Sharp & Dohme Corp. Ax1 and ax189 pcsk9 antagonists and variants
SMT201900505T1 (en) 2011-03-31 2019-11-13 Adc Therapeutics Sa Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
CN111298119A (en) 2012-01-09 2020-06-19 Adc治疗股份有限公司 Methods for treating triple negative breast cancer and basal-like breast cancer by using inhibitors of kidney associated antigen 1(KAAG1)
KR20150023711A (en) 2012-06-15 2015-03-05 제넨테크, 인크. Anti-pcsk9 antibodies, formulations, dosing, and methods of use
BR112015026513A2 (en) 2013-04-17 2017-07-25 Pfizer n-piperidin-3-ylbenzamide derivatives to treat cardiovascular disease
US9045545B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision medicine by targeting PD-L1 variants for treatment of cancer
US9034332B1 (en) 2014-07-15 2015-05-19 Kymab Limited Precision medicine by targeting rare human PCSK9 variants for cholesterol treatment
US9045548B1 (en) 2014-07-15 2015-06-02 Kymab Limited Precision Medicine by targeting rare human PCSK9 variants for cholesterol treatment
US9051378B1 (en) 2014-07-15 2015-06-09 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8945560B1 (en) 2014-07-15 2015-02-03 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US8986691B1 (en) 2014-07-15 2015-03-24 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9067998B1 (en) 2014-07-15 2015-06-30 Kymab Limited Targeting PD-1 variants for treatment of cancer
US9914769B2 (en) 2014-07-15 2018-03-13 Kymab Limited Precision medicine for cholesterol treatment
US9017678B1 (en) 2014-07-15 2015-04-28 Kymab Limited Method of treating rheumatoid arthritis using antibody to IL6R
US8986694B1 (en) 2014-07-15 2015-03-24 Kymab Limited Targeting human nav1.7 variants for treatment of pain
US8992927B1 (en) 2014-07-15 2015-03-31 Kymab Limited Targeting human NAV1.7 variants for treatment of pain
US8980273B1 (en) 2014-07-15 2015-03-17 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US9023359B1 (en) 2014-07-15 2015-05-05 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
US8883157B1 (en) 2013-12-17 2014-11-11 Kymab Limited Targeting rare human PCSK9 variants for cholesterol treatment
GB201403775D0 (en) 2014-03-04 2014-04-16 Kymab Ltd Antibodies, uses & methods
US9139648B1 (en) 2014-07-15 2015-09-22 Kymab Limited Precision medicine by targeting human NAV1.9 variants for treatment of pain
US9150660B1 (en) 2014-07-15 2015-10-06 Kymab Limited Precision Medicine by targeting human NAV1.8 variants for treatment of pain
WO2017220988A1 (en) 2016-06-20 2017-12-28 Kymab Limited Multispecific antibodies for immuno-oncology
EP3534947A1 (en) 2016-11-03 2019-09-11 Kymab Limited Antibodies, combinations comprising antibodies, biomarkers, uses & methods
WO2018119354A1 (en) 2016-12-23 2018-06-28 President And Fellows Of Harvard College Gene editing of pcsk9
EP4133072A4 (en) 2020-04-09 2024-11-06 Verve Therapeutics, Inc. CHEMICALLY MODIFIED GUIDE RNAS FOR GENOME EDITING WITH CAS9

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5932422A (en) * 1997-11-14 1999-08-03 Millennium Pharmaceuticals, Inc. Modulation of drug resistance via ubiquitin carboxy-terminal hydrolase
WO2000057903A2 (en) * 1999-03-26 2000-10-05 Human Genome Sciences, Inc. 48 human secreted proteins
JP2004501637A (en) * 2000-06-26 2004-01-22 スージェン・インコーポレーテッド New protease

Also Published As

Publication number Publication date
JP2004515217A (en) 2004-05-27
CA2411971A1 (en) 2001-12-27
WO2001098468A2 (en) 2001-12-27
WO2001098468A3 (en) 2003-01-03
EP1292684A2 (en) 2003-03-19

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