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AU2001292739A1 - 1-oxorapamycins - Google Patents

1-oxorapamycins

Info

Publication number
AU2001292739A1
AU2001292739A1 AU2001292739A AU9273901A AU2001292739A1 AU 2001292739 A1 AU2001292739 A1 AU 2001292739A1 AU 2001292739 A AU2001292739 A AU 2001292739A AU 9273901 A AU9273901 A AU 9273901A AU 2001292739 A1 AU2001292739 A1 AU 2001292739A1
Authority
AU
Australia
Prior art keywords
oxorapamycins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001292739A
Inventor
Tianmin Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2001292739A1 publication Critical patent/AU2001292739A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2001292739A 2000-09-27 2001-09-19 1-oxorapamycins Abandoned AU2001292739A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23575000P 2000-09-27 2000-09-27
US60/235,750 2000-09-27
PCT/US2001/029139 WO2002026746A2 (en) 2000-09-27 2001-09-19 1-oxorapamycins

Publications (1)

Publication Number Publication Date
AU2001292739A1 true AU2001292739A1 (en) 2002-04-08

Family

ID=22886760

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001292739A Abandoned AU2001292739A1 (en) 2000-09-27 2001-09-19 1-oxorapamycins

Country Status (3)

Country Link
US (1) US6399625B1 (en)
AU (1) AU2001292739A1 (en)
WO (1) WO2002026746A2 (en)

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US20030176455A1 (en) * 2002-03-13 2003-09-18 Wyeth Method of inhibiting cell death
JP4814520B2 (en) * 2002-05-15 2011-11-16 エンドサイト，インコーポレイテッド Vitamin-mitomycin conjugate
US20040167165A1 (en) * 2003-01-16 2004-08-26 Geetha Shankar Methods of treating conditions associated with an Edg-7 receptor
TWI492750B (en) 2003-01-27 2015-07-21 安德賽特公司 Vitamin-receptor binding drug delivery conjugates, pharmaceutical compositions, uses and preparation processes
AR042938A1 (en) * 2003-02-06 2005-07-06 Wyeth Corp USE OF CCI-779 IN THE TREATMENT OF HEPATIC FIBROSIS
WO2005010010A1 (en) * 2003-07-16 2005-02-03 Wyeth Cci-779 isomer c
CA2532251A1 (en) * 2003-07-25 2005-02-10 Wyeth Cci-779 lyophilized formulations
JP5149620B2 (en) 2004-07-23 2013-02-20 エンドサイト，インコーポレイテッド Bivalent linker and conjugate thereof
KR20070083941A (en) * 2004-10-04 2007-08-24 큐엘티 유에스에이, 인코포레이티드 Eye transfer with a polymer delivery composition
US8313763B2 (en) 2004-10-04 2012-11-20 Tolmar Therapeutics, Inc. Sustained delivery formulations of rapamycin compounds
EP1856131A1 (en) * 2005-03-07 2007-11-21 Wyeth Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin
EP1863816B1 (en) * 2005-03-16 2014-06-25 Endocyte, Inc. Synthesis and purification of pteroic acid and conjugates thereof
EP1874118A4 (en) * 2005-04-27 2009-07-22 Univ Florida MATERIALS AND METHODS FOR IMPROVING THE DEGRADATION OF MUTANT PROTEINS ASSOCIATED WITH A HUMAN DISEASE
EP2382995A3 (en) * 2005-08-19 2013-09-25 Endocyte, Inc. Ligand conjugates of Vinca alkaloids, analogs and derivatives
AU2006279304A1 (en) * 2005-08-19 2007-02-22 Endocyte, Inc. Multi-drug ligand conjugates
US20100104626A1 (en) * 2007-02-16 2010-04-29 Endocyte, Inc. Methods and compositions for treating and diagnosing kidney disease
AU2008224988A1 (en) * 2007-03-14 2008-09-18 Endocyte, Inc. Binding ligand linked drug delivery conjugates of tubulysins
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
BRPI0812970A2 (en) * 2007-06-25 2019-09-24 Endocyte Inc conjugates containing hydrophilic spacers
CN101909441B (en) 2007-10-25 2015-05-13 恩多塞特公司 Tubulysins and processes for preparing
CN102292078A (en) 2008-11-11 2011-12-21 得克萨斯大学体系董事会 Inhibition of mammalian target of rapamycin
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
WO2013013708A1 (en) 2011-07-26 2013-01-31 Fundació Institut D'investigació Biomèdica De Bellvitge Treatment of acute rejection in renal transplant
WO2013126797A1 (en) 2012-02-24 2013-08-29 Purdue Research Foundation Cholecystokinin b receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
CN103705925B (en) 2012-09-29 2018-03-30 段磊 Pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
US9750728B2 (en) 2012-09-29 2017-09-05 Targeted Therapeutics, Llc Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
CA2926747A1 (en) 2012-10-12 2014-04-17 Arlan RICHARDSON Use of mtor inhibitors to treat vascular cognitive impairment
CN104869998A (en) 2012-10-16 2015-08-26 恩多塞特公司 Drug delivery conjugates containing unnatural amino acids and methods of use
EP2968281B1 (en) 2013-03-13 2020-08-05 The Board of Regents of The University of Texas System Mtor inhibitors for prevention of intestinal polyp growth
ES2900426T3 (en) 2013-12-31 2022-03-16 Rapamycin Holdings Llc Oral preparations and use of rapamycin nanoparticles
US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
CA2968049A1 (en) 2014-04-16 2015-10-22 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists
ES2871499T3 (en) 2017-05-15 2021-10-29 Bard Inc C R Medical device with drug elution coating and interlayer
CN113226389B (en) 2018-11-14 2022-11-08 乐通公司 Medical device with drug eluting coating on modified device surface
US20220176084A1 (en) 2019-04-08 2022-06-09 Bard Peripheral Vascular, Inc. Medical device with drug-eluting coating on modified device surface

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US5321009A (en) 1991-04-03 1994-06-14 American Home Products Corporation Method of treating diabetes
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ZA924953B (en) 1991-07-25 1993-04-28 Univ Louisville Res Found Method of treating ocular inflammation
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US5286731A (en) 1991-09-17 1994-02-15 American Home Products Corporation Method of treating immunoinflammatory bowel disease
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Also Published As

Publication number Publication date
US20020061903A1 (en) 2002-05-23
WO2002026746A3 (en) 2002-08-15
WO2002026746A2 (en) 2002-04-04
US6399625B1 (en) 2002-06-04

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