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ATE548034T1 - Pharmazeutische zusammensetzungen mit droxidopa - Google Patents

Pharmazeutische zusammensetzungen mit droxidopa

Info

Publication number
ATE548034T1
ATE548034T1 AT07784556T AT07784556T ATE548034T1 AT E548034 T1 ATE548034 T1 AT E548034T1 AT 07784556 T AT07784556 T AT 07784556T AT 07784556 T AT07784556 T AT 07784556T AT E548034 T1 ATE548034 T1 AT E548034T1
Authority
AT
Austria
Prior art keywords
compounds
pharmaceutical compositions
compositions containing
droxidopa
combinations
Prior art date
Application number
AT07784556T
Other languages
English (en)
Inventor
Michael Roberts
Simon Pedder
Original Assignee
Chelsea Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chelsea Therapeutics Inc filed Critical Chelsea Therapeutics Inc
Application granted granted Critical
Publication of ATE548034T1 publication Critical patent/ATE548034T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/15Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT07784556T 2006-06-28 2007-06-28 Pharmazeutische zusammensetzungen mit droxidopa ATE548034T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80603606P 2006-06-28 2006-06-28
PCT/US2007/072334 WO2008003028A2 (en) 2006-06-28 2007-06-28 Pharmaceutical compositions comprising droxidopa

Publications (1)

Publication Number Publication Date
ATE548034T1 true ATE548034T1 (de) 2012-03-15

Family

ID=38698773

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07784556T ATE548034T1 (de) 2006-06-28 2007-06-28 Pharmazeutische zusammensetzungen mit droxidopa

Country Status (9)

Country Link
US (2) US20080015181A1 (de)
EP (3) EP1948155B1 (de)
AT (1) ATE548034T1 (de)
DK (1) DK1948155T3 (de)
ES (2) ES2383768T3 (de)
HR (1) HRP20120479T1 (de)
PL (1) PL1948155T3 (de)
PT (1) PT1948155E (de)
WO (1) WO2008003028A2 (de)

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US8158149B2 (en) 2004-05-12 2012-04-17 Chelsea Therapeutics, Inc. Threo-DOPS controlled release formulation
WO2004100929A1 (en) 2003-05-12 2004-11-25 Synergia Pharma, Inc. Threo-dops controlled release formulation
EP2134335B1 (de) 2007-03-09 2014-04-23 Chelsea Therapeutics, Inc. Droxidopa und pharmazeutische zusammensetzung davon zur behandlung von fibromyalgie
JP2010521479A (ja) * 2007-03-12 2010-06-24 チェルシー・セラピューティクス,インコーポレイテッド 神経調節性低血圧症の治療のためのドロキシドパおよびその医薬組成物
AU2008248382B2 (en) 2007-05-07 2013-07-18 Chelsea Therapeutics, Inc. Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders
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EP2809315A1 (de) 2012-01-31 2014-12-10 Lundbeck Na Ltd Verbesserung des stabilitätsgrads der körperhaltung durch verabreichung von droxidopa
WO2013142093A1 (en) 2012-03-20 2013-09-26 Chelsea Therapeutics, Inc. Method for the synthesis of droxidopa
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US12378194B2 (en) 2021-05-25 2025-08-05 Atai Therapeutics, Inc. N, n-dimethyltryptamine salts and crystalline salt forms
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GB202212116D0 (en) 2022-08-19 2022-10-05 Beckley Psytech Ltd Pharmaceutically acceptable salts and Compositions thereof
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Also Published As

Publication number Publication date
US20080015181A1 (en) 2008-01-17
EP2363124A1 (de) 2011-09-07
WO2008003028A3 (en) 2008-03-20
PT1948155E (pt) 2012-06-15
EP2363123A1 (de) 2011-09-07
EP1948155B1 (de) 2012-03-07
HRP20120479T1 (hr) 2012-07-31
US20160106694A1 (en) 2016-04-21
EP1948155A2 (de) 2008-07-30
ES2571730T3 (es) 2016-05-26
EP2363124B1 (de) 2016-02-17
DK1948155T3 (da) 2012-07-02
WO2008003028A2 (en) 2008-01-03
ES2383768T3 (es) 2012-06-26
PL1948155T3 (pl) 2012-10-31

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