ATE548034T1 - Pharmazeutische zusammensetzungen mit droxidopa - Google Patents
Pharmazeutische zusammensetzungen mit droxidopaInfo
- Publication number
- ATE548034T1 ATE548034T1 AT07784556T AT07784556T ATE548034T1 AT E548034 T1 ATE548034 T1 AT E548034T1 AT 07784556 T AT07784556 T AT 07784556T AT 07784556 T AT07784556 T AT 07784556T AT E548034 T1 ATE548034 T1 AT E548034T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- pharmaceutical compositions
- compositions containing
- droxidopa
- combinations
- Prior art date
Links
- QXWYKJLNLSIPIN-SFYZADRCSA-N droxidopa Chemical compound OC(=O)[C@H](N)[C@@H](O)C1=CC=C(O)C(O)=C1 QXWYKJLNLSIPIN-SFYZADRCSA-N 0.000 title abstract 2
- 229960001104 droxidopa Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 102100040999 Catechol O-methyltransferase Human genes 0.000 abstract 1
- 108020002739 Catechol O-methyltransferase Proteins 0.000 abstract 1
- 102000003914 Cholinesterases Human genes 0.000 abstract 1
- 108090000322 Cholinesterases Proteins 0.000 abstract 1
- 102000010909 Monoamine Oxidase Human genes 0.000 abstract 1
- 108010062431 Monoamine oxidase Proteins 0.000 abstract 1
- 208000001089 Multiple system atrophy Diseases 0.000 abstract 1
- 206010031127 Orthostatic hypotension Diseases 0.000 abstract 1
- 229940048961 cholinesterase Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80603606P | 2006-06-28 | 2006-06-28 | |
| PCT/US2007/072334 WO2008003028A2 (en) | 2006-06-28 | 2007-06-28 | Pharmaceutical compositions comprising droxidopa |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE548034T1 true ATE548034T1 (de) | 2012-03-15 |
Family
ID=38698773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07784556T ATE548034T1 (de) | 2006-06-28 | 2007-06-28 | Pharmazeutische zusammensetzungen mit droxidopa |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20080015181A1 (de) |
| EP (3) | EP1948155B1 (de) |
| AT (1) | ATE548034T1 (de) |
| DK (1) | DK1948155T3 (de) |
| ES (2) | ES2383768T3 (de) |
| HR (1) | HRP20120479T1 (de) |
| PL (1) | PL1948155T3 (de) |
| PT (1) | PT1948155E (de) |
| WO (1) | WO2008003028A2 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8158149B2 (en) | 2004-05-12 | 2012-04-17 | Chelsea Therapeutics, Inc. | Threo-DOPS controlled release formulation |
| WO2004100929A1 (en) | 2003-05-12 | 2004-11-25 | Synergia Pharma, Inc. | Threo-dops controlled release formulation |
| EP2134335B1 (de) | 2007-03-09 | 2014-04-23 | Chelsea Therapeutics, Inc. | Droxidopa und pharmazeutische zusammensetzung davon zur behandlung von fibromyalgie |
| JP2010521479A (ja) * | 2007-03-12 | 2010-06-24 | チェルシー・セラピューティクス,インコーポレイテッド | 神経調節性低血圧症の治療のためのドロキシドパおよびその医薬組成物 |
| AU2008248382B2 (en) | 2007-05-07 | 2013-07-18 | Chelsea Therapeutics, Inc. | Droxidopa and pharmaceutical composition thereof for the treatment of mood disorders, sleep disorders, or attention deficit disorders |
| US8388656B2 (en) * | 2010-02-04 | 2013-03-05 | Ebi, Llc | Interspinous spacer with deployable members and related method |
| JP5880913B2 (ja) | 2011-05-17 | 2016-03-09 | 三郎 佐古田 | パーキンソン病の体幹症状(姿勢反射異常)の治療剤 |
| EP2809315A1 (de) | 2012-01-31 | 2014-12-10 | Lundbeck Na Ltd | Verbesserung des stabilitätsgrads der körperhaltung durch verabreichung von droxidopa |
| WO2013142093A1 (en) | 2012-03-20 | 2013-09-26 | Chelsea Therapeutics, Inc. | Method for the synthesis of droxidopa |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US12433904B2 (en) | 2019-04-17 | 2025-10-07 | Compass Pathfinder Limited | Methods for treating anxiety disorders, headache disorders, and eating disorders with psilocybin |
| US11759452B2 (en) | 2020-05-08 | 2023-09-19 | Psilera Inc. | Compositions of matter and pharmaceutical compositions |
| EP4397371A3 (de) | 2020-05-19 | 2024-10-30 | Cybin IRL Limited | Deuterierte tryptaminderivate und verfahren zur verwendung |
| GB202008961D0 (en) * | 2020-06-12 | 2020-07-29 | Beckley Psytech Ltd | Pharmaceutical composition |
| EP3941583B9 (de) * | 2020-06-12 | 2023-04-19 | Beckley Psytech Limited | Zusammensetzung enthaltend ein benzoesäuresalz von 5-methoxy-n,n-dimethyltryptamin |
| US12378194B2 (en) | 2021-05-25 | 2025-08-05 | Atai Therapeutics, Inc. | N, n-dimethyltryptamine salts and crystalline salt forms |
| US12264131B2 (en) | 2022-08-19 | 2025-04-01 | Beckley Psytech Limited | Pharmaceutically acceptable salts and compositions thereof |
| GB202212116D0 (en) | 2022-08-19 | 2022-10-05 | Beckley Psytech Ltd | Pharmaceutically acceptable salts and Compositions thereof |
| US12246005B2 (en) | 2023-06-13 | 2025-03-11 | Beckley Psytech Limited | 5-methoxy-n,n-dimethyltryptamine (5-MeO-DMT) formulations |
| WO2025054397A1 (en) * | 2023-09-08 | 2025-03-13 | Atai Therapeutics, Inc. | Parenteral formulations for n,n-dimethyltryptamine (dmt) and dmt analogs, methods of making, and methods of use thereof |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3920728A (en) * | 1973-08-22 | 1975-11-18 | Hoffmann La Roche | Separation and resolution of isomeric forms of 3-(3,4-dihydroxy-phenyl)-serine |
| JPS5419931A (en) * | 1977-07-11 | 1979-02-15 | Sumitomo Chem Co Ltd | Separation of threo, erythro-3-(3,4-dibenzyloxyphenyl)serines |
| US4319046A (en) * | 1977-07-22 | 1982-03-09 | The Sherwin-Williams Company | Preparation of 1,2 diaminobenzene by high pressure acid hydrolysis of benzemidazolone |
| JPS5629551A (en) | 1979-08-20 | 1981-03-24 | Sumitomo Chem Co Ltd | Preparation of optically active threo-3- 3,4- dihydroxyphenyl serine |
| JPS56104815A (en) | 1980-01-23 | 1981-08-20 | Sumitomo Chem Co Ltd | Remedy for peripheral orthostatic hypotension |
| US4421767A (en) * | 1981-06-01 | 1983-12-20 | Merrell Toraude Et Compagnie | Compounds and methods for treating depression |
| JPS5852219A (ja) * | 1981-09-22 | 1983-03-28 | Sumitomo Chem Co Ltd | パ−キンソン病治療剤 |
| US4480109A (en) * | 1982-01-14 | 1984-10-30 | Sumitomo Chemical Company, Limited | Process for producing threo-3-(3,4-dihydroxyphenyl)serine |
| CA1223602A (en) | 1983-05-25 | 1987-06-30 | Naohito Ohashi | Process for producing 3-(3,4-dihydroxyphenyl) serine |
| JPS6067420A (ja) * | 1983-09-22 | 1985-04-17 | Sumitomo Chem Co Ltd | 精神運動興奮抑制剤 |
| JPS6098995A (ja) | 1983-11-04 | 1985-06-01 | Microbial Chem Res Found | 光学活性3−(3,4−ジヒドロキシフエニル)セリン,およびその誘導体の製造法 |
| JPS6185318A (ja) * | 1984-10-04 | 1986-04-30 | Sumitomo Seiyaku Kk | 利尿薬 |
| JPS62106015A (ja) * | 1985-10-31 | 1987-05-16 | Sumitomo Pharmaceut Co Ltd | 抗痴呆薬 |
| DK175069B1 (da) | 1986-03-11 | 2004-05-24 | Hoffmann La Roche | Pyrocatecholderivater |
| YU213587A (en) * | 1986-11-28 | 1989-06-30 | Orion Yhtymae Oy | Process for obtaining new pharmacologic active cateholic derivatives |
| GB8720600D0 (en) * | 1987-09-02 | 1987-10-07 | Saad Al Damluji | Pharmaceutical compositions |
| US5240930A (en) * | 1987-09-02 | 1993-08-31 | National Research Development Corporation | Pharmaceutical compositions for treatment of depression and low blood pressure |
| US5015564A (en) * | 1988-12-23 | 1991-05-14 | Eastman Kodak Company | Stabilizatin of precipitated dispersions of hydrophobic couplers, surfactants and polymers |
| JP2603566B2 (ja) * | 1991-03-27 | 1997-04-23 | 住友製薬株式会社 | 尿失禁治療剤 |
| JP3559572B2 (ja) * | 1993-01-29 | 2004-09-02 | 住友製薬株式会社 | 急性痛および慢性痛用鎮痛剤 |
| JP3764179B2 (ja) * | 1994-07-05 | 2006-04-05 | 克寛 西野 | 運動・意識または言語障害の機能改善剤 |
| DE19619510A1 (de) | 1995-05-18 | 1996-11-21 | Sumitomo Chemical Co | Verfahren zur Herstellung von Threo-3-(3,4-dihydroxyphenyl)serin |
| GB9510481D0 (en) | 1995-05-24 | 1995-07-19 | Orion Yhtymae Oy | New catechol derivatives |
| US6929801B2 (en) * | 1996-02-19 | 2005-08-16 | Acrux Dds Pty Ltd | Transdermal delivery of antiparkinson agents |
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| JPH115738A (ja) * | 1997-06-15 | 1999-01-12 | Katsuhiro Nishino | 脳虚血に伴う神経脱落症状の予防剤および超急性期治療剤 |
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| SK286667B6 (sk) * | 1999-07-01 | 2009-03-05 | Pharmacia & Upjohn Company | Použitie opticky čistého (S,S)-reboxetínu alebo jeho farmaceuticky prijateľnej soli na výrobu lieku na liečenie alebo prevenciu chronického únavového syndrómu |
| US20010047032A1 (en) * | 1999-12-30 | 2001-11-29 | Castillo Gerardo M. | Polyhydroxylated aromatic compounds for the treatment of amyloidosis and alpha-synuclein fibril diseases |
| CA2425125A1 (en) * | 2000-10-12 | 2002-07-25 | Kjell A. Svensson | Method of treating parkinson's disease |
| CA2463624A1 (en) * | 2001-10-15 | 2003-04-24 | National Research Council Of Canada | Anti-glycation agents for preventing age-, diabetes-, and smoking-related complications |
| US6602911B2 (en) * | 2001-11-05 | 2003-08-05 | Cypress Bioscience, Inc. | Methods of treating fibromyalgia |
| EP1490073A4 (de) * | 2002-03-21 | 2006-02-01 | Martin C Hinz | Segmentoptimierungstechnik für das serotonin- und catecholamin-system |
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| WO2005102366A2 (en) * | 2004-04-19 | 2005-11-03 | Philip Maxwell Satow | Lithium combinations, and uses related thereto |
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-
2007
- 2007-06-28 ES ES07784556T patent/ES2383768T3/es active Active
- 2007-06-28 HR HRP20120479TT patent/HRP20120479T1/hr unknown
- 2007-06-28 EP EP07784556A patent/EP1948155B1/de active Active
- 2007-06-28 US US11/770,191 patent/US20080015181A1/en not_active Abandoned
- 2007-06-28 WO PCT/US2007/072334 patent/WO2008003028A2/en not_active Ceased
- 2007-06-28 EP EP11165690A patent/EP2363123A1/de not_active Withdrawn
- 2007-06-28 AT AT07784556T patent/ATE548034T1/de active
- 2007-06-28 PL PL07784556T patent/PL1948155T3/pl unknown
- 2007-06-28 PT PT07784556T patent/PT1948155E/pt unknown
- 2007-06-28 ES ES11165693T patent/ES2571730T3/es active Active
- 2007-06-28 DK DK07784556.8T patent/DK1948155T3/da active
- 2007-06-28 EP EP11165693.0A patent/EP2363124B1/de active Active
-
2015
- 2015-10-16 US US14/885,158 patent/US20160106694A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20080015181A1 (en) | 2008-01-17 |
| EP2363124A1 (de) | 2011-09-07 |
| WO2008003028A3 (en) | 2008-03-20 |
| PT1948155E (pt) | 2012-06-15 |
| EP2363123A1 (de) | 2011-09-07 |
| EP1948155B1 (de) | 2012-03-07 |
| HRP20120479T1 (hr) | 2012-07-31 |
| US20160106694A1 (en) | 2016-04-21 |
| EP1948155A2 (de) | 2008-07-30 |
| ES2571730T3 (es) | 2016-05-26 |
| EP2363124B1 (de) | 2016-02-17 |
| DK1948155T3 (da) | 2012-07-02 |
| WO2008003028A2 (en) | 2008-01-03 |
| ES2383768T3 (es) | 2012-06-26 |
| PL1948155T3 (pl) | 2012-10-31 |
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