ATE319457T1 - Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu - Google Patents
Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazuInfo
- Publication number
- ATE319457T1 ATE319457T1 AT99915411T AT99915411T ATE319457T1 AT E319457 T1 ATE319457 T1 AT E319457T1 AT 99915411 T AT99915411 T AT 99915411T AT 99915411 T AT99915411 T AT 99915411T AT E319457 T1 ATE319457 T1 AT E319457T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- iatrogenic
- age
- derivatives
- treatment
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 2
- 230000000642 iatrogenic effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003697 vitamin B6 derivatives Chemical class 0.000 title 1
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 abstract 6
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 abstract 4
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 4
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 abstract 3
- 239000013589 supplement Substances 0.000 abstract 3
- 239000011726 vitamin B6 Substances 0.000 abstract 3
- 235000019158 vitamin B6 Nutrition 0.000 abstract 3
- 229940011671 vitamin b6 Drugs 0.000 abstract 3
- 230000032683 aging Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 230000037406 food intake Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/061,173 US6051587A (en) | 1998-04-16 | 1998-04-16 | Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE319457T1 true ATE319457T1 (de) | 2006-03-15 |
Family
ID=22034118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99915411T ATE319457T1 (de) | 1998-04-16 | 1999-04-16 | Behandlung iatrogenen und altersbedingten bluthochdruck mit vitamin b6-derivative, und pharmazeutische zusammensetzungen verwendbar dazu |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6051587A (de) |
| EP (1) | EP1071430B1 (de) |
| JP (1) | JP2002512194A (de) |
| AT (1) | ATE319457T1 (de) |
| AU (1) | AU765749B2 (de) |
| BR (1) | BR9909672A (de) |
| CA (1) | CA2328730C (de) |
| DE (1) | DE69930243T2 (de) |
| ES (1) | ES2260906T3 (de) |
| IL (1) | IL139681A0 (de) |
| NZ (1) | NZ508142A (de) |
| WO (1) | WO1999053928A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716858B1 (en) | 1995-08-28 | 2004-04-06 | Kansas University Medical Center | Methods for inhibiting diabetic complications |
| US6043259A (en) * | 1998-07-09 | 2000-03-28 | Medicure Inc. | Treatment of cardiovascular and related pathologies |
| PT1169322E (pt) | 1999-03-08 | 2007-04-30 | Medicure Inc | Análogos de piridoxal para o tratamento de desordens causadas por uma deficiência em vitamina b-6. |
| WO2001003682A2 (en) * | 1999-07-13 | 2001-01-18 | Medicure Inc. | Use of pyridoxin derivatives for the treatment of diabetes and related complications |
| EP1872797A3 (de) * | 1999-08-24 | 2008-04-02 | Medicure International Inc. | Behandlung kardiovaskulärer und verwandter Leiden |
| EP1531157B1 (de) * | 2000-02-29 | 2008-03-19 | Medicure International Inc. | Cardioprotektive Phosphonate |
| US7442689B2 (en) | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
| DE60133323T2 (de) * | 2000-02-29 | 2009-03-05 | Medicure International Inc. | Cardioprotektive Phosphonate |
| CA2404329A1 (en) | 2000-03-28 | 2001-10-04 | Medicure International Inc. | Treatment of cerebrovascular disease |
| WO2001078721A1 (en) * | 2000-04-13 | 2001-10-25 | Mayo Foundation For Medical Education And Research | Aβ42 LOWERING AGENTS |
| US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
| WO2002039994A2 (en) | 2000-11-20 | 2002-05-23 | University Of Kansas Medical Center | Methods for the treatment and prevention of urinary stone disease |
| US7521584B2 (en) * | 2002-07-29 | 2009-04-21 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of disease |
| US20050148517A1 (en) * | 2002-07-29 | 2005-07-07 | Lockwood Samuel F. | Carotenoid ether analogs or derivatives for controlling connexin 43 expression |
| US20050059635A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid ester analogs or derivatives for controlling C-reactive protein levels |
| US7763649B2 (en) | 2002-07-29 | 2010-07-27 | Cardax Pharmaceuticals, Inc. | Carotenoid analogs or derivatives for controlling connexin 43 expression |
| US20050004235A1 (en) * | 2002-07-29 | 2005-01-06 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease |
| US7375133B2 (en) * | 2002-07-29 | 2008-05-20 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| KR20050069975A (ko) * | 2002-07-29 | 2005-07-05 | 하와이 바이오테크, 인코포레이티드 | 질병의 억제 및 완화를 위한 카로티노이드 구조 유사체 |
| US20050143475A1 (en) * | 2002-07-29 | 2005-06-30 | Lockwood Samuel F. | Carotenoid analogs or derivatives for the inhibition and amelioration of ischemic reperfusion injury |
| US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
| US20050049248A1 (en) * | 2002-07-29 | 2005-03-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for controlling C-reactive protein levels |
| US20050026874A1 (en) * | 2002-07-29 | 2005-02-03 | Lockwood Samuel Fournier | Carotenoid ether analogs or derivatives for the inhibition and amelioration of liver disease |
| US7723327B2 (en) | 2002-07-29 | 2010-05-25 | Cardax Pharmaceuticals, Inc. | Carotenoid ester analogs or derivatives for the inhibition and amelioration of liver disease |
| US7345091B2 (en) * | 2002-07-29 | 2008-03-18 | Cardax Pharmaceuticals, Inc. | Carotenoid ether analogs or derivatives for the inhibition and amelioration of disease |
| US20050059659A1 (en) * | 2002-07-29 | 2005-03-17 | Lockwood Samuel Fournier | Carotenoid analogs or derivatives for controlling C-reactive protein levels |
| EP1603548A4 (de) * | 2003-02-05 | 2007-10-10 | Myriad Genetics Inc | Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen |
| AU2004224566A1 (en) * | 2003-03-27 | 2004-10-07 | Medicure Inc. | Compositions for treating angina |
| WO2004084895A2 (en) * | 2003-03-27 | 2004-10-07 | Medicure, Inc. | Modulation of cell death |
| WO2005065069A2 (en) * | 2003-07-11 | 2005-07-21 | Myriad Genetics, Inc. | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease |
| WO2006001877A2 (en) * | 2004-04-13 | 2006-01-05 | Myriad Genetics, Inc. | Combination treatment for neurodegenerative disorders comprising r-flurbiprofen |
| US20060058269A1 (en) * | 2004-04-14 | 2006-03-16 | Lockwood Samuel F | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| WO2005102356A1 (en) * | 2004-04-14 | 2005-11-03 | Hawaii Biotech, Inc. | Carotenoid analogs or derivatives for the inhibition and amelioration of inflammation |
| KR20070004036A (ko) * | 2004-04-29 | 2007-01-05 | 키스톤 리테이닝 월 시스템스, 아이엔씨 | 벽, 옹벽 및 그 외 유사한 것을 위한 베니어 |
| US20060019929A1 (en) * | 2004-07-07 | 2006-01-26 | Albert Friesen | Combination therapies employing platelet aggregation drugs |
| JP2008509169A (ja) * | 2004-08-10 | 2008-03-27 | メディキュア・インターナショナル・インコーポレーテッド | ビタミンb6関連化合物およびace阻害剤を使用する組み合わせ療法ならびに糖尿病疾患の治療のためのその使用 |
| US20070060549A1 (en) * | 2004-08-10 | 2007-03-15 | Friesen Albert D | Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders |
| WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| BRPI0514303A (pt) * | 2004-08-11 | 2008-06-10 | Myriad Genetics Inc | composição farmacêutica e método para tratar distúrbios neurodegenerativos |
| WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
| US20060094749A1 (en) * | 2004-10-28 | 2006-05-04 | Medicure International Inc. | Substituted pyridoxines as anti-platelet agents |
| US7812037B2 (en) * | 2004-10-28 | 2010-10-12 | Medicure International, Inc. | Dual antiplatelet/anticoagulant pyridoxine analogs |
| US7459468B2 (en) * | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
| AU2005309297A1 (en) * | 2004-11-26 | 2006-06-01 | Medicure International Inc. | Novel formulation of pyridoxal 5'-phosphate and method of preparation |
| JP2008526783A (ja) * | 2005-01-05 | 2008-07-24 | メディキュア・インターナショナル・インコーポレーテッド | トリグリセリドレベルを調節するための化合物及び方法 |
| CA2610502A1 (en) | 2005-03-29 | 2006-10-05 | Cardax Pharmaceuticals, Inc. | Reduction in complement activation and inflammation during tissue injury by carotenoids, carotenoid analogs, or derivatives thereof |
| CA2503087A1 (en) * | 2005-03-30 | 2006-09-30 | Medicure International Inc. | Intravenous formulations of pyridoxal 5'-phosphate and method of preparation |
| BRPI0613611A2 (pt) * | 2005-07-22 | 2011-01-18 | Myriad Genetics Inc | formulações de alta concentração de fármaco e formas de dosagens |
| AU2006317440A1 (en) * | 2005-11-28 | 2007-05-31 | Medicure International Inc. | Selected dosage for the treatment of cardiovascular and related pathologies |
| DOP2007000055A (es) | 2006-04-10 | 2007-10-31 | Senosiain S A De C V Lab | Composición farmaceutica que comprende un analgésico y vitaminas |
| EP2046119A2 (de) * | 2006-07-07 | 2009-04-15 | Myriad Genetics, Inc. | Behandlung von psychiatrischen störungen |
| MX2008003230A (es) * | 2008-03-07 | 2009-09-07 | Senosiain S A De C V Lab | Composicion famaceutica oral que comprende la combinacion de una sal de ketorolaco y vitaminas del complejo b. |
| ITMI20121316A1 (it) | 2012-07-27 | 2014-01-28 | Altergon Sa | Complessi di condroitina ad assorbimento transcutaneo |
| WO2014063134A1 (en) * | 2012-10-19 | 2014-04-24 | New York University | Methods for inhibiting osteolysis |
| RU2629367C1 (ru) * | 2016-11-02 | 2017-08-29 | федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) | Нестероидное противовоспалительное средство на основе напроксена, обладающее низкой гастротоксичностью |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR4492M (de) * | 1965-07-07 | 1966-10-10 | ||
| FR6707M (de) * | 1966-04-29 | 1969-02-17 | ||
| FR6723M (de) * | 1966-12-30 | 1969-02-17 | ||
| FR7503M (de) * | 1967-05-30 | 1969-12-08 | ||
| GB1236531A (en) * | 1969-02-12 | 1971-06-23 | Soc D Etudes Prod Chimique | Adenin derivative |
| JPS53121765A (en) * | 1977-04-01 | 1978-10-24 | Chugai Pharmaceut Co Ltd | Pyridoxal derivatives |
| IL62602A (en) * | 1980-05-19 | 1984-06-29 | Labaz Sanofi Nv | Pyridoxine derivatives,their preparation and pharmaceutical compositions containing them |
| US4542026A (en) * | 1983-04-29 | 1985-09-17 | Jose Rios | Method of treating vasomotor disorders |
| US4564614A (en) * | 1984-10-11 | 1986-01-14 | Pfizer Inc. | Antiinflammatory methods |
| FR2641189B1 (fr) * | 1988-06-20 | 1991-05-10 | Timol Mamoojee | Compositions pharmaceutiques contenant de l'acide acetyl salicylique et de la vitamine b6 |
| US20040180865A1 (en) * | 1993-06-04 | 2004-09-16 | Jeffry W. Kreamer | Aspirin and vitamin and/or trace element compositions for the amelioration and treatment of vascular disease |
-
1998
- 1998-04-16 US US09/061,173 patent/US6051587A/en not_active Expired - Fee Related
-
1999
- 1999-04-16 WO PCT/CA1999/000331 patent/WO1999053928A1/en not_active Ceased
- 1999-04-16 DE DE69930243T patent/DE69930243T2/de not_active Expired - Fee Related
- 1999-04-16 CA CA002328730A patent/CA2328730C/en not_active Expired - Fee Related
- 1999-04-16 NZ NZ508142A patent/NZ508142A/xx unknown
- 1999-04-16 ES ES99915411T patent/ES2260906T3/es not_active Expired - Lifetime
- 1999-04-16 JP JP2000544332A patent/JP2002512194A/ja not_active Withdrawn
- 1999-04-16 BR BRPI9909672-2A patent/BR9909672A/pt not_active Application Discontinuation
- 1999-04-16 EP EP99915411A patent/EP1071430B1/de not_active Expired - Lifetime
- 1999-04-16 IL IL13968199A patent/IL139681A0/xx unknown
- 1999-04-16 AT AT99915411T patent/ATE319457T1/de not_active IP Right Cessation
- 1999-04-16 AU AU34029/99A patent/AU765749B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1071430A1 (de) | 2001-01-31 |
| DE69930243D1 (de) | 2006-05-04 |
| AU3402999A (en) | 1999-11-08 |
| ES2260906T3 (es) | 2006-11-01 |
| EP1071430B1 (de) | 2006-03-08 |
| DE69930243T2 (de) | 2006-12-07 |
| NZ508142A (en) | 2002-11-26 |
| CA2328730C (en) | 2007-08-21 |
| CA2328730A1 (en) | 1999-10-28 |
| JP2002512194A (ja) | 2002-04-23 |
| US6051587A (en) | 2000-04-18 |
| IL139681A0 (en) | 2002-02-10 |
| BR9909672A (pt) | 2007-07-31 |
| AU765749B2 (en) | 2003-09-25 |
| WO1999053928A1 (en) | 1999-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |