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AR245719A1 - Un procedimiento para la preparacion de derivados de guanina 9-sustituidos e intermediarios para ser usados en el procedimiento. - Google Patents

Un procedimiento para la preparacion de derivados de guanina 9-sustituidos e intermediarios para ser usados en el procedimiento.

Info

Publication number
AR245719A1
AR245719A1 AR90316421A AR31642190A AR245719A1 AR 245719 A1 AR245719 A1 AR 245719A1 AR 90316421 A AR90316421 A AR 90316421A AR 31642190 A AR31642190 A AR 31642190A AR 245719 A1 AR245719 A1 AR 245719A1
Authority
AR
Argentina
Prior art keywords
substituted
preparation
guanine derivatives
intermediates
substituted guanine
Prior art date
Application number
AR90316421A
Other languages
English (en)
Original Assignee
Gea Farmaceutisk Fabrik As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gea Farmaceutisk Fabrik As filed Critical Gea Farmaceutisk Fabrik As
Application granted granted Critical
Publication of AR245719A1 publication Critical patent/AR245719A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052Imidazole radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE GUANINA 9-SUSTITUIDOS DE LA FORMULA (I) DONDE R ES ALQUILO, SUSTITUIDO O NO CON UNO O MAS GRUPOS HIDROXI, O R ES (II), BENCILO, RIBOSILO, 2'-DEOXIRRIBOSILO O (CH2)(N)-OR(1) DONDE N ES 1 O 2, Y R(1) ES CH2CH2OH O (OHCH2)(2)-CH- Y SALES DE LOS MISMOS, DONDE UNA 5-(TIOCARBAMOIL)AMINO-1H-IMIDAZOL-4-CARBOXAMIDA 1- SUSTITUIDA DE LA FORMULA (III) SE CICLA A) POR TRATAMIENTO CON UNA SAL DE METAL PESADO DEL GRUPO DE LAS SALES CU-, AQ-, PB- Y HQ EN UN MEDIO ALCALINO ACUOSO QUE CONTIENE POR LO MENOS CUATRO EQUIVALENTES DE IONES OH(-), O B) POR TRATAMIENTO CON UN COMPUESTO PEROXI EN UN MEDIO ALCALINO ACUOSO.
AR90316421A 1989-03-20 1990-03-20 Un procedimiento para la preparacion de derivados de guanina 9-sustituidos e intermediarios para ser usados en el procedimiento. AR245719A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK135489A DK135489D0 (da) 1989-03-20 1989-03-20 Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden

Publications (1)

Publication Number Publication Date
AR245719A1 true AR245719A1 (es) 1994-02-28

Family

ID=8103930

Family Applications (1)

Application Number Title Priority Date Filing Date
AR90316421A AR245719A1 (es) 1989-03-20 1990-03-20 Un procedimiento para la preparacion de derivados de guanina 9-sustituidos e intermediarios para ser usados en el procedimiento.

Country Status (28)

Country Link
US (1) US5223619A (es)
EP (1) EP0464112B1 (es)
KR (1) KR0142098B1 (es)
AR (1) AR245719A1 (es)
AT (1) ATE112568T1 (es)
BG (1) BG60590B1 (es)
BR (1) BR9007230A (es)
CA (1) CA2047217A1 (es)
CS (1) CS9001365A3 (es)
DD (1) DD293116A5 (es)
DE (1) DE69013146T2 (es)
DK (2) DK135489D0 (es)
ES (1) ES2061023T3 (es)
FI (1) FI97387C (es)
GE (1) GEP19971014B (es)
GR (1) GR1001096B (es)
HR (1) HRP920907B1 (es)
HU (1) HU206715B (es)
IE (1) IE62042B1 (es)
LT (1) LT3183B (es)
LV (1) LV10455B (es)
NO (1) NO178497C (es)
PL (1) PL163313B1 (es)
RO (1) RO109737B1 (es)
RU (2) RU2090566C1 (es)
SI (1) SI9010545A (es)
WO (1) WO1990011283A1 (es)
YU (1) YU47343B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264599B1 (it) * 1993-06-14 1996-10-04 Solar Chem Sa Processo per la sintesi della 9-(2-idrossietossimetil)- guanina
GB9520364D0 (en) * 1995-10-05 1995-12-06 Chiroscience Ltd Compouundds
US6359145B1 (en) * 1998-07-23 2002-03-19 Fujisawa Pharmaceutical Co., Ltd. Imidazole compounds
US6811595B2 (en) 2002-09-04 2004-11-02 Xerox Corporation Guanidinopyrimidinone compounds and phase change inks containing same
US6860928B2 (en) 2002-09-04 2005-03-01 Xerox Corporation Alkylated urea and triaminotriazine compounds and phase change inks containing same
US6761758B2 (en) 2002-09-04 2004-07-13 Xerox Corporation Alkylated tetrakis(triaminotriazine) compounds and phase change inks containing same
US6872243B2 (en) 2002-09-04 2005-03-29 Xerox Corporation Phase change inks containing gelator additives
US7153349B2 (en) 2004-12-04 2006-12-26 Xerox Corporation Phase change inks containing curable trans-1,2-cyclohexane bis(urea-urethane) compounds
US7144450B2 (en) 2004-12-04 2006-12-05 Xerox Corporation Phase change inks containing trans-1,2-cyclohexane bis(urea-urethane) compounds
US7560587B2 (en) 2004-12-04 2009-07-14 Xerox Corporation Bis[urea-urethane] compounds
US7314949B2 (en) 2004-12-04 2008-01-01 Xerox Corporation Trans-1,2-cyclohexane bis(urea-urethane) compounds
US7220300B2 (en) 2004-12-04 2007-05-22 Xerox Corporation Phase change inks containing bis(urea-urethane) compounds
US7317122B2 (en) 2004-12-04 2008-01-08 Xerox Corporation Curable trans-1,2-cyclohexane bis(urea-urethane) compounds
CN105705284B (zh) 2013-10-29 2019-05-31 舒瑞普国际股份公司 使用丝网印刷钎焊材料钎焊板式换热器的方法;利用该方法制造的板式换热器
CN115504977B (zh) * 2022-09-23 2024-02-09 海南锦瑞制药有限公司 更昔洛韦的制备方法及注射用更昔洛韦的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56152437U (es) * 1980-04-14 1981-11-14
US4602089A (en) * 1982-03-12 1986-07-22 Newport Pharmaceuticals, Inc. Process for preparing purine compounds
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
JPS6055071B2 (ja) * 1982-04-16 1985-12-03 四国化成工業株式会社 イミダゾリル琥珀酸化合物および該化合物を用いるエポキシ樹脂硬化方法
HUT36464A (en) * 1983-05-24 1985-09-30 Newport Pharmaceuticals Process for producing erythro-4-amino-3-/2-hydroxy-3-alkyl/-imidazol-5-carboxamide
EP0219838A3 (en) * 1985-10-22 1988-04-06 Takeda Chemical Industries, Ltd. Carbocyclic purine nucleosides, their production and use
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
US5223619A (en) 1993-06-29
CA2047217A1 (en) 1990-09-21
HRP920907B1 (en) 1998-06-30
WO1990011283A1 (en) 1990-10-04
RU2042668C1 (ru) 1995-08-27
GEP19971014B (en) 1997-04-18
CS275359B2 (en) 1992-02-19
LV10455B (en) 1995-08-20
HU206715B (en) 1992-12-28
BR9007230A (pt) 1992-02-25
IE62042B1 (en) 1994-12-14
HRP920907A2 (hr) 1994-04-30
GR900100212A (en) 1990-07-31
LTIP297A (en) 1994-08-25
NO178497C (no) 1996-04-10
NO178497B (no) 1996-01-02
BG95145A (bg) 1993-12-24
DE69013146T2 (de) 1995-02-16
KR920701208A (ko) 1992-08-11
DK135489D0 (da) 1989-03-20
DK0464112T3 (da) 1995-03-13
DD293116A5 (de) 1991-08-22
PL163313B1 (pl) 1994-03-31
GR1001096B (el) 1993-04-28
FI97387C (fi) 1996-12-10
ATE112568T1 (de) 1994-10-15
HUT59141A (en) 1992-04-28
IE900994L (en) 1990-09-20
LV10455A (lv) 1995-02-20
KR0142098B1 (ko) 1998-06-01
SI9010545A (en) 1997-08-31
FI97387B (fi) 1996-08-30
EP0464112B1 (en) 1994-10-05
LT3183B (en) 1995-03-27
FI914418A0 (fi) 1991-09-19
EP0464112A1 (en) 1992-01-08
RU2090566C1 (ru) 1997-09-20
DE69013146D1 (de) 1994-11-10
NO913686D0 (no) 1991-09-19
RO109737B1 (ro) 1995-05-30
BG60590B1 (en) 1995-09-29
CS9001365A3 (en) 1992-02-19
HU902874D0 (en) 1991-12-30
YU54590A (sh) 1992-12-21
ES2061023T3 (es) 1994-12-01
YU47343B (sh) 1995-01-31
NO913686L (no) 1991-09-19

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