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AR214303A1 - Un procedimiento para preparar nuevos derivados de(cicloalquilalquiloxi-(o tio,o-sulfonil-alquil)-(o alquiloxi fenoxi)-1amino-3-propanol-2 - Google Patents

Un procedimiento para preparar nuevos derivados de(cicloalquilalquiloxi-(o tio,o-sulfonil-alquil)-(o alquiloxi fenoxi)-1amino-3-propanol-2

Info

Publication number
AR214303A1
AR214303A1 AR265315A AR26531576A AR214303A1 AR 214303 A1 AR214303 A1 AR 214303A1 AR 265315 A AR265315 A AR 265315A AR 26531576 A AR26531576 A AR 26531576A AR 214303 A1 AR214303 A1 AR 214303A1
Authority
AR
Argentina
Prior art keywords
alkyloxyphenoxy
1amine
cycloalkylalkyloxy
thio
sulfonyl
Prior art date
Application number
AR265315A
Other languages
English (en)
Spanish (es)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9162099&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR214303(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of AR214303A1 publication Critical patent/AR214303A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AR265315A 1975-11-06 1976-11-02 Un procedimiento para preparar nuevos derivados de(cicloalquilalquiloxi-(o tio,o-sulfonil-alquil)-(o alquiloxi fenoxi)-1amino-3-propanol-2 AR214303A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7533899A FR2330383A1 (fr) 1975-11-06 1975-11-06 Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment

Publications (1)

Publication Number Publication Date
AR214303A1 true AR214303A1 (es) 1979-05-31

Family

ID=9162099

Family Applications (1)

Application Number Title Priority Date Filing Date
AR265315A AR214303A1 (es) 1975-11-06 1976-11-02 Un procedimiento para preparar nuevos derivados de(cicloalquilalquiloxi-(o tio,o-sulfonil-alquil)-(o alquiloxi fenoxi)-1amino-3-propanol-2

Country Status (24)

Country Link
US (2) US4252984A (de)
JP (1) JPS5848543B2 (de)
AR (1) AR214303A1 (de)
AT (1) AT344683B (de)
AU (1) AU501581B2 (de)
BE (1) BE847801A (de)
CA (1) CA1072981A (de)
CH (1) CH602582A5 (de)
DE (1) DE2649605C3 (de)
DK (1) DK145119C (de)
ES (1) ES452920A1 (de)
FI (1) FI62829C (de)
FR (1) FR2330383A1 (de)
GB (1) GB1515978A (de)
GR (1) GR61363B (de)
IE (1) IE43645B1 (de)
IL (1) IL50814A (de)
LU (1) LU76117A1 (de)
NL (1) NL179051C (de)
NO (1) NO142034C (de)
NZ (1) NZ182498A (de)
PT (1) PT65780B (de)
SE (1) SE433208B (de)
ZA (1) ZA766338B (de)

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IT1147311B (it) * 1980-02-13 1986-11-19 Stabil Bioterapico Farmachim Eteri basici di 4-idrossi-benzofenoni con attivita' quali agenti betabloccanti e relativi procedimento di preparazione
ZW9881A1 (en) * 1980-06-02 1981-12-23 Hoffmann La Roche Substituted phenoxyaminopropanol derivatives
DE3125870C2 (de) * 1980-07-09 1994-09-15 William John Louis 3-Aminopropoxyphenyl Derivate, ihre Herstellung und sie enthaltende Arzneimittel
CH643527A5 (en) * 1980-10-24 1984-06-15 Ciba Geigy Ag Process for the preparation of 1-alkylamino-3-(4-(2-lower alkoxy-ethyl)phenoxy)-2-propanols
JPS57108047A (en) * 1980-11-06 1982-07-05 Sandoz Ag 3-aminopropoxyphenyl derivative, manufacture and pharmaceutical composition containing same
US5347050A (en) * 1980-11-06 1994-09-13 Richard Berthold 3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
FI76551C (fi) 1980-11-06 1988-11-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 3-aminopropoxifenylderivat.
DE3125636A1 (de) * 1981-06-30 1983-01-13 Merck Patent Gmbh, 6100 Darmstadt 1-(p-2-isopropoxyethoxymethyl-phenoxy)-3-isopropylamino-propan-2-ol zur senkung des augeninnendrucks und ophtalmikum, enthalten diese verbindung
FR2512443A1 (fr) * 1981-09-10 1983-03-11 Synthelabo Derives de phenoxy-3 propanol-2, leur preparation et leur application en therapeutique
DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
US4450172A (en) * 1982-03-10 1984-05-22 E. I. Du Pont De Nemours And Company Antihypertensive polyhalohydroxyisopropyl phenylalka(e)noic acid esters of alkylaminohydroxypropyloxyphenylalkyl alcohols
FR2536390B1 (fr) * 1982-11-22 1986-03-21 Synthelabo Isomere s du betaxolol, sa preparation et son application en therapeutique
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US5554367A (en) * 1984-10-31 1996-09-10 Alcon Laboratories, Inc. Compositions for treatment of glaucoma
ES8609190A1 (es) * 1985-02-07 1986-07-16 Pharma Investi S A Un procedimiento para preparar eteres fenolicos
US5095151A (en) * 1985-05-21 1992-03-10 American Home Products Corporation Preparation of propranolol hydrochloride macrocrystals
EP0252007A3 (de) * 1986-06-28 1989-07-05 Ciba-Geigy Ag 2-Propanolderivate als Korrosionsinhibitoren
US4694022A (en) * 1986-12-24 1987-09-15 Alcon Laboratories, Inc. Fatty acid salts of betaxolol useful in the treatment of glaucoma
DE3866984D1 (en) * 1987-07-21 1992-01-30 Hoffmann La Roche Phenoxypropanolamine.
FR2672594B1 (fr) * 1991-02-08 1994-07-01 Synthelabo Derives d'ethers de phenols, leur preparation et leur application en therapeutique.
ATE263137T1 (de) 1995-10-10 2004-04-15 William John Louis 3-aminopropoxyphenyl-derivate
CA2193149C (en) * 1995-12-22 2002-04-23 David H. Donabedian Cationic therapuetic agents and delivery systems
US5942633A (en) * 1996-06-19 1999-08-24 Abbott Laboratories Process for the selective alkylation of betaxolol intermediates
US5731463A (en) * 1996-09-23 1998-03-24 Abbott Laboratories Selective alkylation of an alcohol substituted phenol compound
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
US6258350B1 (en) 1999-01-20 2001-07-10 Alcon Manufacturing, Ltd. Sustained release ophthalmic formulation
DE60006584T2 (de) 1999-11-30 2004-09-30 Alcon, Inc. Verwendung von beta-rezeptorenblocker zur herstellung eines medikaments zur behandlung von krankheiten der äusseren retina
WO2002009760A2 (en) * 2000-07-27 2002-02-07 Pharmacia Corporation Epoxy-steroidal aldosterone antagonist and beta-adrenergic antagonist combination therapy for treatment of congestive heart failure
EP1554572B1 (de) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
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CN101287411B (zh) 2005-04-28 2013-03-06 普罗秋斯生物医学公司 药物信息系统及其用途
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AR063469A1 (es) * 2006-07-14 2009-01-28 Ranbaxy Lab Ltd Formas polimorficas de ácido (3r,5r)-7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]-pirrol-1-il]-3, 5-dihidroxi-heptanoico, sal hemicalcio, metodos de preparacion de las mismas, una composicion farmaceutica que las comprende y su uso en el tratamiento de enfermedades
US20080161324A1 (en) * 2006-09-14 2008-07-03 Johansen Lisa M Compositions and methods for treatment of viral diseases
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WO2008112287A1 (en) * 2007-03-12 2008-09-18 Nektar Therapeutics Oligomer-beta blocker conjugates
EP2050441A1 (de) * 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Verwendung von Beta-Blockern für die Herstellung eines Medikaments zur Behandlung von Hämangiomen
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
JP2009040769A (ja) * 2008-07-09 2009-02-26 William John Louis ３−アミノ−プロポキシフェニル誘導体（ｉ）
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AT325022B (de) * 1935-11-15 1975-09-25 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen racemischen oder optisch aktiven n,n'- bis - (3-subst. phenoxy-2-hydroxy - 1 - propyl) - alfa, omega - diaminoalkanen sowie deren säureadditionssalzen
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CA956632A (en) * 1969-05-16 1974-10-22 Yoshitomi Pharmaceutical Industries Phenoxy-aminopropanol derivatives
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GB1458392A (en) * 1973-11-09 1976-12-15 Ici Ltd Optically-active 1-aryloxy-2,3-epoxypropane derivatives

Also Published As

Publication number Publication date
AT344683B (de) 1978-08-10
NO763732L (no) 1977-05-09
SE433208B (sv) 1984-05-14
AU501581B2 (en) 1979-06-21
ATA812076A (de) 1977-12-15
NO142034B (no) 1980-03-10
DE2649605C3 (de) 1981-04-02
JPS5285146A (en) 1977-07-15
DE2649605B2 (de) 1980-07-10
AU1925976A (en) 1978-05-11
DK495476A (da) 1977-05-07
FI763132A7 (de) 1977-05-07
DK145119B (da) 1982-09-06
IL50814A (en) 1979-11-30
GB1515978A (en) 1978-06-28
SE7612177L (sv) 1977-05-07
IE43645L (en) 1977-05-06
IE43645B1 (en) 1981-04-22
ES452920A1 (es) 1977-11-01
DK145119C (da) 1983-02-14
NL179051C (nl) 1986-07-01
PT65780A (fr) 1976-12-01
LU76117A1 (de) 1978-07-10
GR61363B (en) 1978-10-30
BE847801A (fr) 1977-02-14
NO142034C (no) 1980-06-18
PT65780B (fr) 1978-05-10
DE2649605A1 (de) 1977-05-18
FI62829B (fi) 1982-11-30
CA1072981A (en) 1980-03-04
FR2330383A1 (fr) 1977-06-03
FR2330383B1 (de) 1979-09-21
US4252984A (en) 1981-02-24
FI62829C (fi) 1983-03-10
IL50814A0 (en) 1977-01-31
NZ182498A (en) 1978-04-03
JPS5848543B2 (ja) 1983-10-28
US4311708A (en) 1982-01-19
NL7612123A (nl) 1977-05-10
CH602582A5 (de) 1978-07-31
ZA766338B (en) 1977-10-26
NL179051B (nl) 1986-02-03

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