AR130928A2 - Composición inmunogénica - Google Patents
Composición inmunogénicaInfo
- Publication number
- AR130928A2 AR130928A2 ARP230102918A ARP230102918A AR130928A2 AR 130928 A2 AR130928 A2 AR 130928A2 AR P230102918 A ARP230102918 A AR P230102918A AR P230102918 A ARP230102918 A AR P230102918A AR 130928 A2 AR130928 A2 AR 130928A2
- Authority
- AR
- Argentina
- Prior art keywords
- glycoconjugate
- pneumoniae serotype
- pneumoniae
- immunogenic composition
- serotype
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- A61J1/06—Ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Composiciones inmunogénicas que comprenden antígenos de sacárido capsular de Streptococcus pneumoniae conjugados (glicoconjugados) de S. pneumoniae serotipo 15B. Reivindicación 1: Una composición inmunogénica caracterizada porque comprende un glicoconjugado de S. pneumoniae serotipo 15B. Reivindicación 2: La composición inmunogénica de acuerdo con la reivindicación 1, caracterizada porque comprende al menos un glicoconjugado de S. pneumoniae serotipo 15B, al menos un glicoconjugado de S. pneumoniae serotipo 22F y al menos un glicoconjugado de S. pneumoniae serotipo 33F. Reivindicación 3: La composición inmunogénica de acuerdo con la reivindicación 1, caracterizada porque comprende al menos un glicoconjugado de S. pneumoniae serotipo 15B, al menos un glicoconjugado de S. pneumoniae serotipo 22F, al menos un glicoconjugado de S. pneumoniae serotipo 33F, al menos un glicoconjugado de S. pneumoniae serotipo 12F, al menos un glicoconjugado de S. pneumoniae serotipo 10A, al menos un glicoconjugado de S. pneumoniae serotipo 11A y al menos un glicoconjugado de S. pneumoniae serotipo 8.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461929547P | 2014-01-21 | 2014-01-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR130928A2 true AR130928A2 (es) | 2025-01-29 |
Family
ID=52630420
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100151A AR099445A1 (es) | 2014-01-21 | 2015-01-20 | Composiciones inmunogénicas que comprenden antígenos sacáridos capsulares conjugados y usos de los mismos |
| ARP230102919A AR130929A2 (es) | 2014-01-21 | 2023-10-31 | Composiciones inmunogénicas que comprenden glicoconjugados de serotipos de streptococcus pneumoniae |
| ARP230102918A AR130928A2 (es) | 2014-01-21 | 2023-10-31 | Composición inmunogénica |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100151A AR099445A1 (es) | 2014-01-21 | 2015-01-20 | Composiciones inmunogénicas que comprenden antígenos sacáridos capsulares conjugados y usos de los mismos |
| ARP230102919A AR130929A2 (es) | 2014-01-21 | 2023-10-31 | Composiciones inmunogénicas que comprenden glicoconjugados de serotipos de streptococcus pneumoniae |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9492559B2 (es) |
| EP (3) | EP3616716A3 (es) |
| JP (6) | JP6335326B2 (es) |
| KR (5) | KR20200108496A (es) |
| CN (6) | CN110859957B (es) |
| AR (3) | AR099445A1 (es) |
| AU (6) | AU2015208821B2 (es) |
| CA (3) | CA2937186C (es) |
| DK (1) | DK3096785T3 (es) |
| ES (1) | ES2820824T3 (es) |
| FR (2) | FR22C1028I2 (es) |
| HU (3) | HUE051728T2 (es) |
| IL (6) | IL312327B1 (es) |
| LU (2) | LUC00268I2 (es) |
| MX (4) | MX379051B (es) |
| NO (2) | NO2022021I1 (es) |
| NZ (5) | NZ755770A (es) |
| PE (2) | PE20212335A1 (es) |
| PH (2) | PH12016501243B1 (es) |
| PL (1) | PL3096785T3 (es) |
| PT (1) | PT3096785T (es) |
| RU (1) | RU2771293C2 (es) |
| SA (2) | SA520420930B1 (es) |
| SG (2) | SG10201803187VA (es) |
| SI (1) | SI3096785T1 (es) |
| TW (4) | TWI679987B (es) |
| WO (1) | WO2015110941A2 (es) |
| ZA (1) | ZA201603925B (es) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6824997B1 (en) * | 1998-09-18 | 2004-11-30 | Binax, Inc. | Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies |
| US9134303B1 (en) | 1998-08-25 | 2015-09-15 | Alere Scarborough, Inc. | ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto |
| EP2425853A1 (en) | 2005-04-08 | 2012-03-07 | Wyeth LLC | Multivalent Pneumococcal Polysaccharide-Protein Conjugate Composition |
| US9517274B2 (en) | 2012-08-16 | 2016-12-13 | Pfizer Inc. | Glycoconjugation processes and compositions |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| CA2937184A1 (en) * | 2014-01-21 | 2015-07-30 | Pfizer Inc. | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof |
| RU2743793C1 (ru) * | 2014-01-21 | 2021-02-26 | Пфайзер Инк. | Капсульные полисахариды Streptococcus pneumoniae и их конъюгаты |
| PT3096785T (pt) | 2014-01-21 | 2020-10-13 | Pfizer | Composições imunogénicas que compreendem antigénios de sacáridos capsulares conjugados e utilizações das mesmas |
| MX395525B (es) * | 2015-01-15 | 2025-03-25 | Pfizer | Composiciones inmunogenicas para usar en vacunas neumococicas. |
| JP6882193B2 (ja) * | 2015-04-28 | 2021-06-02 | バイオロジカル イー リミテッド | 微生物莢膜多糖類からタンパク質および他の不純物を分離するための方法 |
| TWI718144B (zh) * | 2015-05-04 | 2021-02-11 | 美商輝瑞股份有限公司 | B型鏈球菌多醣-蛋白質軛合物、製造軛合物之方法、含軛合物之免疫原性組成物、及其用途 |
| MY192183A (en) * | 2015-07-21 | 2022-08-05 | Pfizer | Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof |
| GB201518684D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| CA3005524C (en) | 2015-11-20 | 2023-10-10 | Pfizer Inc. | Immunogenic compositions for use in pneumococcal vaccines |
| CN106110316A (zh) * | 2016-06-27 | 2016-11-16 | 北京智飞绿竹生物制药有限公司 | 一种肺炎球菌结合物组合疫苗的制备方法 |
| AU2017306711B2 (en) * | 2016-08-05 | 2022-08-04 | Sk Bioscience Co., Ltd. | Multivalent pneumococcal polysaccharide-protein conjugate composition |
| TWI770044B (zh) * | 2016-08-05 | 2022-07-11 | 南韓商Sk生物科技股份有限公司 | 多價肺炎球菌多醣-蛋白質共軛物組成物(一) |
| JP2018042864A (ja) * | 2016-09-15 | 2018-03-22 | 株式会社三洋物産 | 遊技機 |
| AR109621A1 (es) * | 2016-10-24 | 2018-12-26 | Janssen Pharmaceuticals Inc | Formulaciones de vacunas contra glucoconjugados de expec |
| CN108144052A (zh) * | 2016-12-02 | 2018-06-12 | 武汉博沃生物科技有限公司 | 肺炎链球菌多糖-蛋白质缀合物及其制取方法和用途 |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| MA47223A (fr) * | 2016-12-30 | 2019-11-06 | Sutrovax Inc | Conjugués polypeptide-antigène avec des acides aminés non naturels |
| HRP20220573T1 (hr) * | 2017-01-20 | 2022-06-10 | Pfizer Inc. | Imunogeni pripravci, namijenjeni upotrebi u pneumokoknim cjepivima |
| EP3576759B1 (en) | 2017-01-31 | 2025-09-24 | Merck Sharp & Dohme LLC | Methods for production of capsular polysaccharide protein conjugates from streptococcus pneumoniae serotype 19f |
| KR20240169144A (ko) | 2017-01-31 | 2024-12-02 | 머크 샤프 앤드 돔 엘엘씨 | 다당류-단백질 접합체 제조 방법 |
| WO2018144799A1 (en) | 2017-02-03 | 2018-08-09 | SCHADECK, Eva, Barbara | Haemophilus influenzae saccharide-carrier conjugate compositions and uses thereof |
| US11090374B2 (en) | 2017-02-24 | 2021-08-17 | Merck Sharp & Dohme Corp. | Enhancing immunogenicity of Streptococcus pneumoniae polysaccharide-protein conjugates |
| PT3585803T (pt) | 2017-02-24 | 2025-12-22 | Merck Sharp & Dohme | Formulações de vacina pneumocócica conjugada |
| WO2018227177A1 (en) * | 2017-06-10 | 2018-12-13 | Inventprise, Llc | Multivalent conjugate vaccines with bivalent or multivalent conjugate polysaccharides that provide improved immunogenicity and avidity |
| US10729763B2 (en) | 2017-06-10 | 2020-08-04 | Inventprise, Llc | Mixtures of polysaccharide-protein pegylated compounds |
| US11690900B2 (en) * | 2017-08-14 | 2023-07-04 | University Of Georgia Research Foundation, Inc. | Proteins having pneumococcal capsule degrading activity and methods of use |
| JP2020531421A (ja) * | 2017-08-16 | 2020-11-05 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | 肺炎球菌コンジュゲートワクチン製剤 |
| KR20250046326A (ko) * | 2017-09-07 | 2025-04-02 | 머크 샤프 앤드 돔 엘엘씨 | 폐렴구균 폴리사카라이드 및 면역원성 폴리사카라이드-담체 단백질 접합체에서의 그의 용도 |
| FI3678654T3 (fi) * | 2017-09-07 | 2024-09-02 | Merck Sharp & Dohme Llc | Pneumokokkipolysakkaridit ja niiden käyttö immunogeenisissä polysakkaridi-kantajaproteiini-konjugaateissa |
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| JP7397000B2 (ja) | 2018-04-30 | 2023-12-12 | メルク・シャープ・アンド・ドーム・エルエルシー | 凍結乾燥変異ジフテリア毒素のジメチルスルホキシド中均一溶液を提供する方法 |
| JP7506605B6 (ja) * | 2018-04-30 | 2024-07-16 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎球菌莢膜多糖類担体タンパク質複合体の製造方法 |
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| WO2020009462A1 (ko) * | 2018-07-06 | 2020-01-09 | 주식회사 유바이오로직스 | 다가 폐렴구균 다당체-단백질 접합체를 포함하는 면역원성 조성물, 및 이를 포함하는 폐렴구균에 의한 질환 예방 백신 |
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| US12048739B2 (en) | 2018-09-23 | 2024-07-30 | Biological E Limited | Purified capsular polysaccharides of Streptococcus pneumoniae |
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