AR110748A1 - Proteínas toxinas pesticidas activas contra insectos lepidópteros - Google Patents
Proteínas toxinas pesticidas activas contra insectos lepidópterosInfo
- Publication number
- AR110748A1 AR110748A1 ARP180100081A ARP180100081A AR110748A1 AR 110748 A1 AR110748 A1 AR 110748A1 AR P180100081 A ARP180100081 A AR P180100081A AR P180100081 A ARP180100081 A AR P180100081A AR 110748 A1 AR110748 A1 AR 110748A1
- Authority
- AR
- Argentina
- Prior art keywords
- seq
- bcw
- amino acid
- acid sequence
- sequence
- Prior art date
Links
- 108700012359 toxins Proteins 0.000 title abstract 2
- 241000238631 Hexapoda Species 0.000 title 1
- 239000000575 pesticide Substances 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 5
- 230000000749 insecticidal effect Effects 0.000 abstract 5
- 108090000623 proteins and genes Proteins 0.000 abstract 5
- 102000004169 proteins and genes Human genes 0.000 abstract 5
- 239000012634 fragment Substances 0.000 abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 239000002917 insecticide Substances 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 241000255777 Lepidoptera Species 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
- A01N37/46—N-acyl derivatives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/22—Bacillus
- A01N63/23—B. thuringiensis
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P7/00—Arthropodicides
- A01P7/04—Insecticides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Environmental Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Insects & Arthropods (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
En la presente se describen secuencias de nucleótidos que codifican una proteína insecticida que presenta una actividad inhibidora sobre los lepidópteros, así como también proteínas insecticidas a las que se hace referencia en la presente como BCW 001, BCW 002, BCW 003, y quimeras que contienen proteína tóxica BCW e insecticida toxinas BCW, y métodos para detectar la presencia de las secuencias de nucleótidos o el insecticida en una muestra biológica. Reivindicación 1: Un constructo polinucleotídico que comprende una secuencia de nucleótidos que codifica: (a) una proteína insecticida que tiene la secuencia de aminoácidos que comprende los aminoácidos 1 a 607 de una secuencia seleccionada del grupo que consiste en la SEQ ID Nº 2, SEQ ID Nº 4, SEQ ID Nº 6, SEQ ID Nº 8, SEQ ID Nº 10, y SEQ ID Nº 12, o uno de sus fragmentos insecticidas; (b) un fragmento polipeptídico que presenta al menos un 95% de identidad con respecto a la secuencia de aminoácidos de (a); (c) un fragmento polipeptídico que presenta al menos un 84% de identidad con respecto a la secuencia de aminoácidos de (a); (d) un fragmento polipeptídico que presenta al menos un 64% de identidad con respecto a la secuencia de aminoácidos de (a); o (e) una proteína insecticida que tiene la secuencia de aminoácidos de la posición 7 a 607 como se indica en cualquiera de las SEQ ID Nº 2, 4, 6, 8, 10 ó 12, en donde dicha secuencia de nucleótidos está operativamente unida a una secuencia promotora heteróloga.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762445313P | 2017-01-12 | 2017-01-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR110748A1 true AR110748A1 (es) | 2019-05-02 |
Family
ID=62840064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180100081A AR110748A1 (es) | 2017-01-12 | 2018-01-12 | Proteínas toxinas pesticidas activas contra insectos lepidópteros |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US10703782B2 (es) |
| EP (1) | EP3568485A4 (es) |
| JP (1) | JP7264815B2 (es) |
| KR (1) | KR102624543B1 (es) |
| CN (3) | CN117947082A (es) |
| AR (1) | AR110748A1 (es) |
| BR (1) | BR112019014278A2 (es) |
| CA (2) | CA3049658A1 (es) |
| CO (1) | CO2019008595A2 (es) |
| CR (1) | CR20190367A (es) |
| MX (2) | MX388347B (es) |
| PH (1) | PH12019501600A1 (es) |
| UA (1) | UA128156C2 (es) |
| UY (1) | UY37567A (es) |
| WO (1) | WO2018132556A1 (es) |
| ZA (1) | ZA201904418B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CN110982829B (zh) * | 2019-12-23 | 2021-10-29 | 隆平生物技术(海南)有限公司 | 一种用于作物抗虫害的基因组合及其载体和应用 |
| WO2021186045A1 (en) * | 2020-03-20 | 2021-09-23 | Bayer Aktiengesellschaft | Composition comprising multiple baculoviruses to target difficult insect species |
| EP4262400A4 (en) | 2020-12-21 | 2025-01-08 | Monsanto Technology LLC | NEW INSECT INHIBITORY PROTEINS |
| UY39585A (es) | 2020-12-23 | 2022-07-29 | Monsanto Technology Llc | Proteínas que exhiben actividad inhibidora de insectos frente a plagas con importancia agrícola de plantas de cultivo y semillas |
| PE20240230A1 (es) | 2020-12-31 | 2024-02-16 | Monsanto Technology Llc | Novedosas proteinas inhibidoras de insectos |
| CN113793639B (zh) * | 2021-08-03 | 2024-01-05 | 杭州瑞丰生物科技有限公司 | 一种管理玉米螟对Bt毒素抗性的方法 |
| CN114657276B (zh) * | 2022-03-04 | 2023-07-07 | 江汉大学 | 检测水稻转基因品系的引物对组合、试剂盒及检测方法 |
| CN115491428B (zh) * | 2022-03-04 | 2025-09-12 | 江汉大学 | 检测棉花转基因品系的引物对组合、试剂盒及检测方法 |
| CN120647738A (zh) * | 2023-10-27 | 2025-09-16 | 安徽农业大学 | 一种杀虫蛋白及其在防治鳞翅目昆虫中的应用 |
| CN120718122B (zh) * | 2025-08-18 | 2025-12-02 | 隆平生物技术(海南)有限公司 | 一种提高植物抗虫害特性的抗虫蛋白Cry166及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341092C (en) * | 1985-12-12 | 2000-09-05 | David L. Edwards | Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby |
| JP4389075B2 (ja) * | 1996-11-20 | 2009-12-24 | モンサント・テクノロジー・エルエルシー | 広域スペクトルのデルタ−エンドトキシン |
| US7557186B2 (en) * | 2002-03-27 | 2009-07-07 | Council Of Scientific & Industrial Research | Chimeric CrylE δ endotoxin and methods of controlling insects |
| PT1885176T (pt) * | 2005-05-27 | 2016-11-28 | Monsanto Technology Llc | Evento mon89788 de soja e métodos para a sua deteção |
| EP2204094A1 (en) | 2008-12-29 | 2010-07-07 | Bayer CropScience AG | Method for improved utilization of the production potential of transgenic plants Introduction |
| WO2010147879A1 (en) * | 2009-06-16 | 2010-12-23 | Dow Agrosciences Llc | Dig-10 insecticidal cry toxins |
| NZ601105A (en) | 2009-12-16 | 2014-10-31 | Dow Agrosciences Llc | Insecticidal protein combination comprising cry1ab and cry2aa for controlling european corn borer, and methods for insect resistance management |
| UA111592C2 (uk) | 2010-07-07 | 2016-05-25 | Сінгента Партісіпейшнс Аг | Спосіб контролю над твердокрилими комахами-шкідниками |
| PT2699685T (pt) | 2011-04-20 | 2018-05-09 | Devgen Nv | Subregulação da expressão de genes em pragas de insetos |
| MX356526B (es) * | 2012-03-09 | 2018-06-01 | Vestaron Corp | Produccion de peptidos toxicos, expresion de peptido en plantas y combinaciones de peptidos ricos en cisteina. |
| WO2015144652A2 (en) * | 2014-03-27 | 2015-10-01 | Bayer Cropscience Ag | Heterocyclic compounds for the control of unwanted microorganisms |
| EP3715363A1 (en) * | 2014-10-16 | 2020-09-30 | Monsanto Technology LLC | Novel chimeric insecticidal proteins toxic or inhibitory to lepidopteran pests |
| WO2016061392A1 (en) * | 2014-10-16 | 2016-04-21 | Monsanto Technology Llc | Proteins toxic or inhibitory to lepidopteran insects |
| AR104833A1 (es) * | 2015-07-01 | 2017-08-16 | Syngenta Participations Ag | Composiciones y métodos para controlar plagas de plantas |
| BR112018002475A2 (pt) * | 2015-08-07 | 2018-09-18 | Basf Se | método para o controle das pragas de um vegetal de milho e utilização de um ou mais componentes da árvore de ginkgo |
| CN105348374B (zh) * | 2015-12-01 | 2018-08-17 | 中国农业科学院植物保护研究所 | 获得高活性Cry1Ai蛋白突变体的方法及其突变体 |
-
2018
- 2018-01-11 US US15/868,676 patent/US10703782B2/en active Active
- 2018-01-11 CN CN202410083301.9A patent/CN117947082A/zh active Pending
- 2018-01-11 UA UAA201909213A patent/UA128156C2/uk unknown
- 2018-01-11 CR CR20190367A patent/CR20190367A/es unknown
- 2018-01-11 MX MX2019008357A patent/MX388347B/es unknown
- 2018-01-11 CA CA3049658A patent/CA3049658A1/en active Pending
- 2018-01-11 WO PCT/US2018/013298 patent/WO2018132556A1/en not_active Ceased
- 2018-01-11 JP JP2019537830A patent/JP7264815B2/ja active Active
- 2018-01-11 CN CN201880010953.2A patent/CN110267976B/zh active Active
- 2018-01-11 KR KR1020197022233A patent/KR102624543B1/ko active Active
- 2018-01-11 BR BR112019014278-9A patent/BR112019014278A2/pt unknown
- 2018-01-11 CN CN202410080110.7A patent/CN117947081A/zh active Pending
- 2018-01-11 EP EP18738537.2A patent/EP3568485A4/en active Pending
- 2018-01-11 CA CA3229266A patent/CA3229266A1/en active Pending
- 2018-01-12 UY UY0001037567A patent/UY37567A/es active IP Right Grant
- 2018-01-12 AR ARP180100081A patent/AR110748A1/es unknown
-
2019
- 2019-07-05 ZA ZA2019/04418A patent/ZA201904418B/en unknown
- 2019-07-08 PH PH12019501600A patent/PH12019501600A1/en unknown
- 2019-07-11 MX MX2021011210A patent/MX2021011210A/es unknown
- 2019-08-08 CO CONC2019/0008595A patent/CO2019008595A2/es unknown
-
2020
- 2020-06-05 US US16/894,459 patent/US11702455B2/en active Active
-
2023
- 2023-05-17 US US18/319,022 patent/US12240874B2/en active Active
-
2025
- 2025-01-17 US US19/030,888 patent/US20250163110A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN117947082A (zh) | 2024-04-30 |
| US20200369733A1 (en) | 2020-11-26 |
| PH12019501600A1 (en) | 2020-02-24 |
| CA3049658A1 (en) | 2018-07-19 |
| US10703782B2 (en) | 2020-07-07 |
| UA128156C2 (uk) | 2024-04-24 |
| RU2019125252A (ru) | 2021-02-12 |
| ZA201904418B (en) | 2020-12-23 |
| KR102624543B1 (ko) | 2024-01-15 |
| UY37567A (es) | 2018-08-31 |
| CA3229266A1 (en) | 2018-07-19 |
| KR20190103254A (ko) | 2019-09-04 |
| WO2018132556A1 (en) | 2018-07-19 |
| US12240874B2 (en) | 2025-03-04 |
| CO2019008595A2 (es) | 2019-09-30 |
| MX2019008357A (es) | 2019-12-02 |
| EP3568485A4 (en) | 2021-04-14 |
| US20230348543A1 (en) | 2023-11-02 |
| US20180208631A1 (en) | 2018-07-26 |
| CN110267976A (zh) | 2019-09-20 |
| CN110267976B (zh) | 2024-01-26 |
| CR20190367A (es) | 2019-09-25 |
| EP3568485A1 (en) | 2019-11-20 |
| US11702455B2 (en) | 2023-07-18 |
| MX388347B (es) | 2025-03-19 |
| RU2019125252A3 (es) | 2021-10-18 |
| JP7264815B2 (ja) | 2023-04-25 |
| MX2021011210A (es) | 2021-10-22 |
| CN117947081A (zh) | 2024-04-30 |
| US20250163110A1 (en) | 2025-05-22 |
| JP2020503879A (ja) | 2020-02-06 |
| BR112019014278A2 (pt) | 2020-03-03 |
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