[go: up one dir, main page]

AR104867A1 - Genes pesticidas y métodos de uso - Google Patents

Genes pesticidas y métodos de uso

Info

Publication number
AR104867A1
AR104867A1 ARP160101621A ARP160101621A AR104867A1 AR 104867 A1 AR104867 A1 AR 104867A1 AR P160101621 A ARP160101621 A AR P160101621A AR P160101621 A ARP160101621 A AR P160101621A AR 104867 A1 AR104867 A1 AR 104867A1
Authority
AR
Argentina
Prior art keywords
polypeptides
methods
amino acid
polypeptide
acid sequence
Prior art date
Application number
ARP160101621A
Other languages
English (en)
Original Assignee
Agbiome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agbiome Inc filed Critical Agbiome Inc
Publication of AR104867A1 publication Critical patent/AR104867A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
    • C12N15/8285—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for nematode resistance
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pest Control & Pesticides (AREA)
  • Insects & Arthropods (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se proveen composiciones con actividad pesticida y métodos de uso de las mismas. Las composiciones incluyen moléculas de ácidos nucleicos recombinantes y sintéticos que codifican los polipéptidos, construcciones de ADN y vectores que comprenden las moléculas de acido nucleico, células huésped que comprenden los vectores, y anticuerpos para los polipéptidos. Las secuencias de nucleótidos que codifican los polipéptidos se pueden utilizar en construcciones de ADN o casetes de expresión para la transformación y expresión en organismos de interés. Las composiciones y métodos provistos son útiles para la producción de organismos con una mejor resistencia o tolerancia a las plagas. También se proporcionan plantas y semillas transgénicas que comprenden una secuencia de nucleótidos que codifica una proteína pesticida de la presente. Tales plantas son resistentes a los insectos y otras plagas. Se proveen métodos para la producción de los diversos polipéptidos descriptos en la presente, y para el uso de esos polipéptidos en el control o eliminación de una plaga. También se incluyen métodos y kits para la detección de polipéptidos de la presente en una muestra. Reivindicación 1: Un polipéptido recombinante que posee actividad pesticida, caracterizado porque comprende: (a) un polipéptido que comprende una secuencia de aminoácidos que posee por lo menos 90% por ciento de identidad de secuencia respecto de una secuencia de aminoácidos seleccionada del grupo integrado por las secuencias listadas en las Ids. de Sec. Nº 96, 79, 117, 316, 56, 57, 167, 276, 267, 109, 121, 75, ó 22; o (b) un polipéptido que comprende la secuencia de aminoácidos listada en las Ids. de Sec. Nº 96, 79, 117, 316, 56, 57, 167, 276, 267, 109, 121, 75, ó 22.
ARP160101621A 2015-06-03 2016-06-02 Genes pesticidas y métodos de uso AR104867A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562170345P 2015-06-03 2015-06-03

Publications (1)

Publication Number Publication Date
AR104867A1 true AR104867A1 (es) 2017-08-23

Family

ID=56404283

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160101621A AR104867A1 (es) 2015-06-03 2016-06-02 Genes pesticidas y métodos de uso

Country Status (8)

Country Link
US (4) US10364439B2 (es)
EP (2) EP3960864A3 (es)
CN (2) CN108271390A (es)
AR (1) AR104867A1 (es)
BR (1) BR112017025929A2 (es)
CA (1) CA2987598A1 (es)
MA (2) MA46313A (es)
WO (1) WO2016196013A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL274151B (en) 2015-05-21 2022-07-01 Harpoon Therapeutics Inc Trispecific binding proteins and methods of use
US10036037B2 (en) * 2015-08-18 2018-07-31 Monsanto Technology Llc Insect inhibitory proteins
CN119060177A (zh) 2016-05-20 2024-12-03 哈普恩治疗公司 单结构域血清白蛋白结合蛋白质
US11623958B2 (en) 2016-05-20 2023-04-11 Harpoon Therapeutics, Inc. Single chain variable fragment CD3 binding proteins
MX2019006043A (es) 2016-11-23 2019-09-26 Harpoon Therapeutics Inc Proteína de unión de antígeno prostático específico de membrana.
BR112019010602A2 (pt) 2016-11-23 2019-12-17 Harpoon Therapeutics Inc proteínas trispecíficas para psma e métodos de uso
BR112019015582A2 (pt) 2017-01-30 2020-03-10 AgBiome, Inc. Genes pesticidas e métodos de uso
WO2018160754A2 (en) 2017-02-28 2018-09-07 Harpoon Therapeutics, Inc. Inducible monovalent antigen binding protein
CA3063362A1 (en) 2017-05-12 2018-11-15 Harpoon Therapeutics, Inc. Msln targeting trispecific proteins and methods of use
JP7090347B2 (ja) 2017-05-12 2022-06-24 ハープーン セラピューティクス，インク． メソテリン結合タンパク質
EP3694529B1 (en) 2017-10-13 2024-06-26 Harpoon Therapeutics, Inc. Trispecific proteins and methods of use
IL315737A (en) 2017-10-13 2024-11-01 Harpoon Therapeutics Inc B-cell maturation antigen-binding proteins
BR112020023330A2 (pt) 2018-05-14 2021-04-20 Harpoon Therapeutics, Inc. porção de ligação para ativação condicional de moléculas de imunoglobulina
US12195544B2 (en) 2018-09-21 2025-01-14 Harpoon Therapeutics, Inc. EGFR binding proteins and methods of use
WO2020069028A1 (en) 2018-09-25 2020-04-02 Harpoon Therapeutics, Inc. Dll3 binding proteins and methods of use
CN114245806A (zh) 2019-05-14 2022-03-25 哈普恩治疗公司 EpCAM结合蛋白及使用方法
WO2021126772A1 (en) * 2019-12-20 2021-06-24 Syngenta Crop Protection Ag Insecticidal proteins
EP4106806A4 (en) 2020-02-21 2024-07-24 Harpoon Therapeutics, Inc. FLT3-BINDING PROTEINS AND METHODS OF USE
WO2022115524A2 (en) * 2020-11-24 2022-06-02 AgBiome, Inc. Pesticidal genes and methods of use

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US5569597A (en) 1985-05-13 1996-10-29 Ciba Geigy Corp. Methods of inserting viral DNA into plant material
US4853331A (en) 1985-08-16 1989-08-01 Mycogen Corporation Cloning and expression of Bacillus thuringiensis toxin gene toxic to beetles of the order Coleoptera
US5268463A (en) 1986-11-11 1993-12-07 Jefferson Richard A Plant promoter α-glucuronidase gene construct
US5608142A (en) 1986-12-03 1997-03-04 Agracetus, Inc. Insecticidal cotton plants
US5039523A (en) 1988-10-27 1991-08-13 Mycogen Corporation Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
US5023179A (en) 1988-11-14 1991-06-11 Eric Lam Promoter enhancer element for gene expression in plant roots
US5110732A (en) 1989-03-14 1992-05-05 The Rockefeller University Selective gene expression in plants
US5240842A (en) 1989-07-11 1993-08-31 Biotechnology Research And Development Corporation Aerosol beam microinjector
EP0452269B1 (en) 1990-04-12 2002-10-09 Syngenta Participations AG Tissue-preferential promoters
US5498830A (en) 1990-06-18 1996-03-12 Monsanto Company Decreased oil content in plant seeds
CA2051562C (en) 1990-10-12 2003-12-02 Jewel M. Payne Bacillus thuringiensis isolates active against dipteran pests
US5459252A (en) 1991-01-31 1995-10-17 North Carolina State University Root specific gene promoter
US5399680A (en) 1991-05-22 1995-03-21 The Salk Institute For Biological Studies Rice chitinase promoter
WO1993004177A1 (en) 1991-08-27 1993-03-04 Agricultural Genetics Company Limited Proteins with insecticidal properties against homopteran insects and their use in plant protection
EP0612208B1 (en) 1991-10-04 2004-09-15 North Carolina State University Pathogen-resistant transgenic plants
TW261517B (es) 1991-11-29 1995-11-01 Mitsubishi Shozi Kk
US5428148A (en) 1992-04-24 1995-06-27 Beckman Instruments, Inc. N4 - acylated cytidinyl compounds useful in oligonucleotide synthesis
US5401836A (en) 1992-07-16 1995-03-28 Pioneer Hi-Bre International, Inc. Brassica regulatory sequence for root-specific or root-abundant gene expression
US5743477A (en) 1992-08-27 1998-04-28 Dowelanco Insecticidal proteins and method for plant protection
US5849870A (en) 1993-03-25 1998-12-15 Novartis Finance Corporation Pesticidal proteins and strains
NZ263445A (en) 1993-03-25 1996-11-26 Ciba Geigy Ag Bacillus strains producing pesticidal protein during vegetive growth
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5633363A (en) 1994-06-03 1997-05-27 Iowa State University, Research Foundation In Root preferential promoter
US5608144A (en) 1994-08-12 1997-03-04 Dna Plant Technology Corp. Plant group 2 promoters and uses thereof
US5659026A (en) 1995-03-24 1997-08-19 Pioneer Hi-Bred International ALS3 promoter
US5723440A (en) * 1995-06-07 1998-03-03 Mycogen Corporation Controlling hemipteran insect pests with Bacillus thuringiensis
US5837876A (en) 1995-07-28 1998-11-17 North Carolina State University Root cortex specific gene promoter
US6072050A (en) 1996-06-11 2000-06-06 Pioneer Hi-Bred International, Inc. Synthetic promoters
US6063756A (en) 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
WO1998044137A2 (en) 1997-04-03 1998-10-08 Novartis Ag Plant pest control
WO1999043819A1 (en) 1998-02-26 1999-09-02 Pioneer Hi-Bred International, Inc. Family of maize pr-1 genes and promoters
AU762993C (en) 1998-02-26 2004-06-10 Pioneer Hi-Bred International, Inc. Constitutive maize promoters
ES2252964T3 (es) 1998-08-20 2006-05-16 Pioneer Hi-Bred International, Inc. Promotores preferidos de semillas.
WO2000012733A1 (en) 1998-08-28 2000-03-09 Pioneer Hi-Bred International, Inc. Seed-preferred promoters from end genes
US6468523B1 (en) 1998-11-02 2002-10-22 Monsanto Technology Llc Polypeptide compositions toxic to diabrotic insects, and methods of use
CA2371442A1 (en) 1999-05-04 2000-11-09 Monsanto Technology Llc Coleopteran-toxic polypeptide compositions and insect-resistant transgenic plants
CA2384967A1 (en) 1999-09-15 2001-03-22 Monsanto Technology Llc Lepidopteran-active bacillus thuringiensis .delta.-endotoxin compositions and methods of use
CA2396392C (en) 1999-11-29 2015-04-21 Midwest Oilseeds, Inc. Methods and compositions for the introduction of molecules into cells
US20050183161A1 (en) 2003-10-14 2005-08-18 Athenix Corporation AXMI-010, a delta-endotoxin gene and methods for its use
WO2005066202A2 (en) 2003-12-22 2005-07-21 E.I. Du Pont De Nemours And Company Bacillus cry9 family members
US7473822B1 (en) 2005-06-27 2009-01-06 Iowa State University Research Foundation, Inc. Soybean transformation and regeneration using half-seed explant
NZ573398A (en) 2006-06-14 2011-11-25 Athenix Corp Axmi-031, axmi-039, axmi-040 and axmi-049, a family of delta-endotoxin genes and methods for their use
EP3150625B1 (en) 2006-06-15 2021-01-27 BASF Agricultural Solutions Seed US LLC A family of pesticidal proteins and methods for their use
EP2245198A1 (en) * 2008-02-04 2010-11-03 Massachusetts Institute of Technology Selection of nucleic acids by solution hybridization to oligonucleotide baits
MX351227B (es) * 2008-06-25 2017-09-14 Athenix Corp Genes de toxinas y métodos para su uso.
JP2011526791A (ja) * 2008-07-02 2011-10-20 アテニックス・コーポレーション Ｂａｃｉｌｌｕｓｔｈｕｒｉｎｇｉｅｎｓｉｓ由来のＶｉｐ３Ａ殺昆虫性タンパク質であるＡＸＭＩ−１１５、ＡＸＭＩ−１１３、ＡＸＭＩ−００５、ＡＸＭＩ−１６３およびＡＸＭＩ−１８４並びにその使用法
EA026111B1 (ru) * 2009-02-27 2017-03-31 Атеникс Корпорейшн Пестицидные белки и способы их применения
HUE032365T2 (en) 2009-07-02 2017-09-28 Athenix Corp AXMI-205 pesticide gene and methods of application
CA2785195A1 (en) * 2009-12-21 2011-07-14 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis gene with coleopteran activity
WO2011084324A2 (en) 2009-12-21 2011-07-14 Pioneer Hi-Bred International, Inc. Novel bacillus thuringiensis gene with lepidopteran activity
CN103154247A (zh) 2010-08-19 2013-06-12 先锋国际良种公司 对鳞翅目昆虫具有活性的新苏云金杆菌基因
US8878007B2 (en) 2011-03-10 2014-11-04 Pioneer Hi Bred International Inc Bacillus thuringiensis gene with lepidopteran activity
BR112014003911A2 (pt) * 2011-08-19 2017-03-14 Synthetic Genomics Inc método integrado para a identificação de alto rendimento de novas composições pesticidas e seu uso
CN103890181A (zh) 2011-08-22 2014-06-25 拜尔作物科学公司 修饰植物基因组的方法和手段
CA2866166C (en) * 2012-03-09 2023-10-17 Vestaron Corporation Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
RU2016110842A (ru) * 2013-09-25 2017-10-30 Пронутриа Биосайенсис, Инк. Композиции и составы для предотвращения и уменьшения опухолеобразования, пролиферации и инвазии раковых клеток, и способы их получения и применения при лечении раковых заболеваний

Also Published As

Publication number Publication date
WO2016196013A2 (en) 2016-12-08
US10364439B2 (en) 2019-07-30
WO2016196013A3 (en) 2017-03-16
MA55776A (fr) 2022-03-02
US20190284571A1 (en) 2019-09-19
CA2987598A1 (en) 2016-12-08
CN108271390A (zh) 2018-07-10
EP3303595A2 (en) 2018-04-11
US20160355842A1 (en) 2016-12-08
EP3960864A2 (en) 2022-03-02
EP3960864A3 (en) 2022-06-15
BR112017025929A2 (pt) 2018-08-14
US20180163223A1 (en) 2018-06-14
US10421976B2 (en) 2019-09-24
MA46313A (fr) 2021-04-28
CN114805503A (zh) 2022-07-29
US20210054403A1 (en) 2021-02-25

Similar Documents

Publication Publication Date Title
AR104867A1 (es) Genes pesticidas y métodos de uso
CL2020001838A1 (es) Genes pesticidas y métodos de uso. (divisional solicitud 201702681)
MX2018007534A (es) Genes pesticidas y metodos de uso.
MX2019002608A (es) Genes pesticidas y metodos de uso.
AR104490A1 (es) Genes pesticidas y métodos de uso de pesticidas
AR103212A1 (es) Genes pesticidas y métodos de uso
PH12021550691A1 (en) Pesticidal genes and methods of use
AR107122A1 (es) Genes pesticidas y métodos de uso
AR110953A1 (es) Genes pesticidas y métodos de uso
AR109512A1 (es) Genes pesticidas y métodos de uso
AR111369A1 (es) Genes pesticidas y métodos de uso
AR113099A1 (es) Genes pesticidas y métodos de uso

Legal Events

Date Code Title Description
FA Abandonment or withdrawal