AR099023A1 - Pirazolil-heteroarilamidas como agentes plaguicidas - Google Patents
Pirazolil-heteroarilamidas como agentes plaguicidasInfo
- Publication number
- AR099023A1 AR099023A1 ARP150100005A ARP150100005A AR099023A1 AR 099023 A1 AR099023 A1 AR 099023A1 AR P150100005 A ARP150100005 A AR P150100005A AR P150100005 A ARP150100005 A AR P150100005A AR 099023 A1 AR099023 A1 AR 099023A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- substituted
- nitrogen
- cycloalkyl
- alkynyl
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 14
- 229910052757 nitrogen Inorganic materials 0.000 abstract 10
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 4
- 125000000304 alkynyl group Chemical group 0.000 abstract 4
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 4
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- -1 C1−6-carbonyl alkyl Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 2
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 2
- 125000004414 alkyl thio group Chemical group 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 150000001721 carbon Chemical group 0.000 abstract 2
- 125000003636 chemical group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004656 alkyl sulfonylamino group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/76—1,3-Oxazoles; Hydrogenated 1,3-oxazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/10—Insect repellent
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Reivindicación 1: Compuestos de fórmula general (1), en la que R¹ representa hidrógeno, alquilo C₁₋₆, alquenilo C₃₋₆, alquinilo C₃₋₆, cicloalquilo C₃₋₇, alquil C₁₋₆-carbonilo, alcoxi C₁₋₆-carbonilo, aril-alquilo C₁₋₃, heteroaril-alquilo C₁₋₃ dado el caso sustituidos; las agrupaciones químicas A¹ representa CR² o nitrógeno, A² representa CR³ o nitrógeno, A³ representa CR⁴ o nitrógeno, y A⁴ representa CR⁵ o nitrógeno, en las que no más de tres de las agrupaciones químicas A¹ a A⁴ representan al mismo tiempo nitrógeno; R², R³, R⁴ y R⁵ representan independientemente uno de otro hidrógeno, halógeno, ciano, nitro, alquilo C₁₋₆, cicloalquilo C₃₋₆, alcoxi C₁₋₆, N-alcoxi C₁₋₆-imino-alquilo C₁₋₃, alquil C₁₋₆-sulfanilo, alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfonilo, N-alquil C₁₋₆-amino o N, N-di-alquil C₁₋₆-amino dado el caso sustituidos; si ninguna de las agrupaciones A² y A³ representan nitrógeno, R³ y R⁴ pueden formar junto con el átomo de carbono al que están unidos, un anillo de 5 ó 6 miembros, que contiene 0, 1 ó 2 átomos de nitrógeno y/o 0 ó 1 átomos de oxígeno y/o 0 ó 1 átomos de azufre, o si ninguna de las agrupaciones A¹ y A² representa nitrógeno, R² y R³ pueden formar junto con el átomo de carbono al que están unidos, un anillo de 5 ó 6 miembros, que contiene 0, 1 ó 2 átomos de nitrógeno y/o 0 ó 1 átomos de oxígeno y/o 0 ó 1 átomos de azufre; W representa oxígeno o azufre; Q representa hidrógeno, amino o una de las agrupaciones alquilo, alquiloxi, alquenilo, alquinilo, cicloalquilo, heterociclilo, cicloalquilalquilo, arilalquilo, heteroarilalquilo, alcoxicarbonilo dado el caso sustituidas, o una agrupación N-alquilamino, N-alquilcarbonilamino, N, N-dialquilamino, alquilsulfonilamino; o Q representa un arilo sustituido dado el caso de una a cinco veces con V, o representa un heteroarilo dado el caso sustituido de una a cinco veces con V, en donde V representa halógeno, ciano, nitro, alquilo, alquenilo, alquinilo, cicloalquilo, alcoxi, N-alcoxiiminoalquilo, alquilsulfanilo, alquilsulfinilo, alquilsulfonilo, N,N-dialquilamino dado el caso sustituidos; R⁶ independientemente uno de otro representa halógeno, ciano, nitro, amino o un alquilo C₁₋₆, alquil C₁₋₆-oxi, alquil C₁₋₆-carbonilo, alquil C₁₋₆-sulfanilo, alquil C₁₋₆-sulfinilo, alquil C₁₋₆-sulfonilo dado el caso sustituidos, y n representa los valores 0 - 2; Z¹ representa un alquilo y cicloalquilo dado el caso sustituidos, y Z² representa hidrógeno, halógeno, ciano, nitro, amino o un alquilo, alquilcarbonilo, alquilsulfanilo, alquilsulfinilo, alquilsulfonilo dado el caso sustituidos, y Z³ representa hidrógeno o un alquilo, cicloalquilo, alquenilo, alquinilo, arilo o hetarilo dado el caso sustituidos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14150153 | 2014-01-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR099023A1 true AR099023A1 (es) | 2016-06-22 |
Family
ID=49883025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150100005A AR099023A1 (es) | 2014-01-03 | 2015-01-05 | Pirazolil-heteroarilamidas como agentes plaguicidas |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10273226B2 (es) |
| EP (1) | EP3089972B1 (es) |
| JP (1) | JP2017502964A (es) |
| KR (1) | KR20160104065A (es) |
| CN (1) | CN106061965A (es) |
| AR (1) | AR099023A1 (es) |
| AU (1) | AU2014375265B2 (es) |
| BR (1) | BR112016017527B1 (es) |
| CA (1) | CA2935646A1 (es) |
| CL (1) | CL2016001670A1 (es) |
| CR (1) | CR20160311A (es) |
| DO (1) | DOP2016000157A (es) |
| ES (1) | ES2683693T3 (es) |
| IL (1) | IL246549A0 (es) |
| MX (1) | MX2016008653A (es) |
| PH (1) | PH12016501319A1 (es) |
| RU (1) | RU2016131792A (es) |
| TW (1) | TW201540705A (es) |
| UY (1) | UY35940A (es) |
| WO (1) | WO2015101622A1 (es) |
| ZA (1) | ZA201605020B (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170107216A1 (en) | 2015-10-19 | 2017-04-20 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| SG11201804152RA (en) | 2015-11-19 | 2018-06-28 | Incyte Corp | Heterocyclic compounds as immunomodulators |
| MA44075A (fr) | 2015-12-17 | 2021-05-19 | Incyte Corp | Dérivés de n-phényl-pyridine-2-carboxamide et leur utilisation en tant que modulateurs des interactions protéine/protéine pd-1/pd-l1 |
| EP3828171A1 (en) | 2015-12-22 | 2021-06-02 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| AR108396A1 (es) | 2016-05-06 | 2018-08-15 | Incyte Corp | Compuestos heterocíclicos como inmunomoduladores |
| TW201808902A (zh) | 2016-05-26 | 2018-03-16 | 美商英塞特公司 | 作為免疫調節劑之雜環化合物 |
| AU2017281285C1 (en) | 2016-06-20 | 2022-05-12 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| EP3484866B1 (en) | 2016-07-14 | 2022-09-07 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| EP3504198B1 (en) | 2016-08-29 | 2023-01-25 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| DK3512833T3 (da) | 2016-09-15 | 2020-10-12 | Boehringer Ingelheim Int | Heteroarylcarboxamidforbindelser som inhibitorer af ripk2 |
| MA46641A (fr) * | 2016-10-31 | 2019-09-04 | Scripps Research Inst | Méthodes et compositions permettant d'empêcher la transmission de maladies propagées par un vecteur |
| WO2018119286A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Bicyclic heteroaromatic compounds as immunomodulators |
| EP3558989B1 (en) | 2016-12-22 | 2021-04-14 | Incyte Corporation | Triazolo[1,5-a]pyridine derivatives as immunomodulators |
| IL295660A (en) | 2016-12-22 | 2022-10-01 | Incyte Corp | Benzooxazole derivatives as immunomodulators |
| US20180179179A1 (en) | 2016-12-22 | 2018-06-28 | Incyte Corporation | Heterocyclic compounds as immunomodulators |
| PE20200005A1 (es) | 2016-12-22 | 2020-01-06 | Incyte Corp | Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de internalizacion pd-l1 |
| WO2018177993A1 (de) | 2017-03-31 | 2018-10-04 | Bayer Cropscience Aktiengesellschaft | Pyrazole zur bekämpfung von arthropoden |
| CN109206397B (zh) * | 2017-06-29 | 2022-06-07 | 沈阳中化农药化工研发有限公司 | 一种胡椒酸衍生物及其制备和应用 |
| KR20250067967A (ko) | 2018-03-30 | 2025-05-15 | 인사이트 코포레이션 | 면역조절제로서 복소환형 화합물 |
| HUE061503T2 (hu) | 2018-05-11 | 2023-07-28 | Incyte Corp | Tetrahidro-imidazo[4,5-C]piridin-származékok mint PD-L1 immunmodulátorok |
| US12448391B2 (en) | 2019-06-07 | 2025-10-21 | Elanco Tiergesundheit Ag | Bicyclic derivatives for treating endoparasites |
| EP4010342A1 (en) | 2019-08-09 | 2022-06-15 | Incyte Corporation | Salts of a pd-1/pd-l1 inhibitor |
| TWI879811B (zh) | 2019-09-30 | 2025-04-11 | 美商英塞特公司 | 作為免疫調節劑之吡啶并[3,2-d]嘧啶化合物 |
| PH12022551136A1 (en) | 2019-11-11 | 2023-10-09 | Incyte Corp | Salts and crystalline forms of a pd-1/pd-l1 inhibitor |
| AR122189A1 (es) * | 2020-06-04 | 2022-08-24 | Syngenta Crop Protection Ag | Composiciones fungicidas |
| TW202233615A (zh) | 2020-11-06 | 2022-09-01 | 美商英塞特公司 | Pd—1/pd—l1抑制劑之結晶形式 |
| US11780836B2 (en) | 2020-11-06 | 2023-10-10 | Incyte Corporation | Process of preparing a PD-1/PD-L1 inhibitor |
| CN116670114A (zh) | 2020-11-06 | 2023-08-29 | 因赛特公司 | 用于制备pd-1/pd-l1抑制剂以及其盐和结晶形式的方法 |
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-
2014
- 2014-12-30 CA CA2935646A patent/CA2935646A1/en not_active Abandoned
- 2014-12-30 US US15/109,630 patent/US10273226B2/en active Active
- 2014-12-30 AU AU2014375265A patent/AU2014375265B2/en active Active
- 2014-12-30 CN CN201480076689.4A patent/CN106061965A/zh active Pending
- 2014-12-30 ES ES14824853.7T patent/ES2683693T3/es active Active
- 2014-12-30 WO PCT/EP2014/079440 patent/WO2015101622A1/de not_active Ceased
- 2014-12-30 JP JP2016544062A patent/JP2017502964A/ja active Pending
- 2014-12-30 EP EP14824853.7A patent/EP3089972B1/de active Active
- 2014-12-30 CR CR20160311A patent/CR20160311A/es unknown
- 2014-12-30 TW TW103146182A patent/TW201540705A/zh unknown
- 2014-12-30 MX MX2016008653A patent/MX2016008653A/es unknown
- 2014-12-30 UY UY0001035940A patent/UY35940A/es not_active Application Discontinuation
- 2014-12-30 BR BR112016017527-1A patent/BR112016017527B1/pt active IP Right Grant
- 2014-12-30 KR KR1020167021012A patent/KR20160104065A/ko not_active Withdrawn
- 2014-12-30 RU RU2016131792A patent/RU2016131792A/ru not_active Application Discontinuation
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2015
- 2015-01-05 AR ARP150100005A patent/AR099023A1/es unknown
-
2016
- 2016-06-23 DO DO2016000157A patent/DOP2016000157A/es unknown
- 2016-06-29 CL CL2016001670A patent/CL2016001670A1/es unknown
- 2016-06-30 IL IL246549A patent/IL246549A0/en unknown
- 2016-07-01 PH PH12016501319A patent/PH12016501319A1/en unknown
- 2016-07-19 ZA ZA201605020A patent/ZA201605020B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2016008653A (es) | 2016-09-26 |
| EP3089972A1 (de) | 2016-11-09 |
| AU2014375265A1 (en) | 2016-07-21 |
| IL246549A0 (en) | 2016-08-31 |
| ZA201605020B (en) | 2019-10-30 |
| CL2016001670A1 (es) | 2017-05-26 |
| EP3089972B1 (de) | 2018-05-16 |
| KR20160104065A (ko) | 2016-09-02 |
| ES2683693T3 (es) | 2018-09-27 |
| BR112016017527B1 (pt) | 2021-01-05 |
| CR20160311A (es) | 2016-08-16 |
| TW201540705A (zh) | 2015-11-01 |
| US20160326140A1 (en) | 2016-11-10 |
| WO2015101622A1 (de) | 2015-07-09 |
| RU2016131792A3 (es) | 2018-08-16 |
| JP2017502964A (ja) | 2017-01-26 |
| US10273226B2 (en) | 2019-04-30 |
| AU2014375265B2 (en) | 2018-11-01 |
| RU2016131792A (ru) | 2018-02-06 |
| CA2935646A1 (en) | 2015-07-09 |
| CN106061965A (zh) | 2016-10-26 |
| PH12016501319A1 (en) | 2016-08-15 |
| BR112016017527A2 (pt) | 2018-05-08 |
| DOP2016000157A (es) | 2016-07-31 |
| UY35940A (es) | 2015-07-31 |
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