AR095603A1 - Composiciones para la higiene bucal que contienen antimetabolitos de desoxiazúcares - Google Patents
Composiciones para la higiene bucal que contienen antimetabolitos de desoxiazúcaresInfo
- Publication number
- AR095603A1 AR095603A1 ARP140101228A ARP140101228A AR095603A1 AR 095603 A1 AR095603 A1 AR 095603A1 AR P140101228 A ARP140101228 A AR P140101228A AR P140101228 A ARP140101228 A AR P140101228A AR 095603 A1 AR095603 A1 AR 095603A1
- Authority
- AR
- Argentina
- Prior art keywords
- agent
- deoxy
- sugar
- agents
- microbial biofilm
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 7
- 229940100197 antimetabolite Drugs 0.000 title abstract 5
- 239000002256 antimetabolite Substances 0.000 title abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 8
- 150000008266 deoxy sugars Chemical class 0.000 abstract 7
- 230000000813 microbial effect Effects 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 5
- 230000000340 anti-metabolite Effects 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 230000000593 degrading effect Effects 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 210000000214 mouth Anatomy 0.000 abstract 2
- 229940034610 toothpaste Drugs 0.000 abstract 2
- 239000000606 toothpaste Substances 0.000 abstract 2
- AOYNUTHNTBLRMT-SLPGGIOYSA-N 2-deoxy-2-fluoro-aldehydo-D-glucose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](F)C=O AOYNUTHNTBLRMT-SLPGGIOYSA-N 0.000 abstract 1
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 abstract 1
- PNNNRSAQSRJVSB-JGWLITMVSA-N D-quinovose Chemical compound C[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O PNNNRSAQSRJVSB-JGWLITMVSA-N 0.000 abstract 1
- 208000006558 Dental Calculus Diseases 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
- 239000003082 abrasive agent Substances 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000002269 analeptic agent Substances 0.000 abstract 1
- 230000002882 anti-plaque Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 239000007844 bleaching agent Substances 0.000 abstract 1
- 239000008376 breath freshener Substances 0.000 abstract 1
- 229940112822 chewing gum Drugs 0.000 abstract 1
- 235000015218 chewing gum Nutrition 0.000 abstract 1
- 239000012459 cleaning agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000003906 humectant Substances 0.000 abstract 1
- 239000002324 mouth wash Substances 0.000 abstract 1
- 229940051866 mouthwash Drugs 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- -1 opaquers Substances 0.000 abstract 1
- 210000003296 saliva Anatomy 0.000 abstract 1
- 230000035807 sensation Effects 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- 239000004034 viscosity adjusting agent Substances 0.000 abstract 1
- 150000003751 zinc Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/08—Deoxysugars; Unsaturated sugars; Osones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/02—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/591—Mixtures of compounds not provided for by any of the codes A61K2800/592 - A61K2800/596
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
En la presente se describen composiciones para la higiene bucal que comprenden un antimetabolito de desoxiazúcar, y métodos para inhibir la formación de biopelícula microbiana y/o degradar una biopelícula microbiana en un sujeto. Reivindicación 1: Un método para inhibir la formación de biopelícula microbiana y/o degradaruna biopelícula microbiana en la cavidad bucal de un sujeto, caracterizado porque comprende administrar al sujeto una composición para la higiene bucal que comprende un antimetabolito de desoxiazúcar sin agente antibacteriano adicional y un portador aceptable a nivel bucal. Reivindicación 2: El método de acuerdo con la reivindicación 1, caracterizado porque elantimetabolito de desoxiazúcar es un compuesto de fórmula (1), en donde: R¹ es H, OH, CH₃, NH₂ o halógeno; R² es H, OH, CH₃, NH₂ o halógeno; R³ es H, OH, CH₃, NH₂ o halógeno; R⁴ es H, OH, NH₂ o halógeno; y al menos tres entre R¹, R², R³ y R⁴ son OH. Reivindicación 10: El método de acuerdo con la reivindicación 9, caracterizado porque elantimetabolito de desoxiazúcar se selecciona entre el grupo que consiste en 6-desoxi-D-glucosa, 2-fluoro-2-desoxi-D-glucosa, y sus mezclas. Reivindicación 11: El método de acuerdo con la reivindicación 8, caracterizado porque elantimetabolito de desoxiazúcar es 2-amino-2-desoxi-D-manosamina. Reivindicación 16: Una composición para la higiene bucal para inhibir la formación de biopelícula microbiana y/o degradar una biopelícula microbiana en la cavidad bucal de un sujeto, caracterizada porque comprende un antimetabolito de desoxiazúcar, en donde el antimetabolito de desoxiazúcar está presente en la composición a una concentración menor a aproximadamente 1% en peso sobre la base del peso total de la composición; un portador aceptable a nivel bucal para una pasta dental, una crema dental, un enjuague bucal, una goma de mascar o un adhesivo para dentadura postiza; uno o más agentes seleccionados entre el grupo que consiste en agente anti-placa, agente blanqueador, agente de limpieza, agente saborizante, agente edulcorante, agentes de adhesión, agentes tensoactivos, moduladores de espuma, abrasivos, agentes modificadores del pH, humectantes, agentes para la sensación bucal, colorantes, abrasivo, agente de control de sarro (anti-cálculos), fuente de iones fluoruro, agentes estimuladores de saliva, agente anti-sensibilidad, agente antioxidante, nutrientes, modificadores de la viscosidad, diluyentes, opacadores, agentes refrescantes del aliento, y sales de zinc, y combinaciones de los mismos; y no contiene un agente antibacteriano adicional.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361792953P | 2013-03-15 | 2013-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR095603A1 true AR095603A1 (es) | 2015-10-28 |
Family
ID=50483560
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140101228A AR095603A1 (es) | 2013-03-15 | 2014-03-17 | Composiciones para la higiene bucal que contienen antimetabolitos de desoxiazúcares |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20160000680A1 (es) |
| EP (1) | EP2970350B1 (es) |
| CN (1) | CN105377865B (es) |
| AR (1) | AR095603A1 (es) |
| AU (1) | AU2014233917B2 (es) |
| BR (1) | BR112015023757A8 (es) |
| MX (1) | MX378054B (es) |
| TW (1) | TWI511748B (es) |
| WO (1) | WO2014151567A1 (es) |
| ZA (1) | ZA201507011B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3654769B1 (en) | 2017-07-18 | 2024-07-24 | Lanxess Corporation | A method for biofilm dispersal |
| JP7341143B2 (ja) | 2017-12-20 | 2023-09-08 | スリーエム イノベイティブ プロパティズ カンパニー | 口腔用組成物及び使用方法 |
| EP3733154A1 (en) * | 2019-05-03 | 2020-11-04 | Omya International AG | Magnesium ion-containing materials as white pigments in oral care compositions |
| WO2022178003A1 (en) * | 2021-02-17 | 2022-08-25 | Colgate-Palmolive Company | Prebiotic oral care compositions and methods |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3940476A (en) * | 1972-03-20 | 1976-02-24 | General Foods Corporation | Oral preparations for preventing dental plaque |
| US4143126A (en) * | 1977-07-01 | 1979-03-06 | Colgate Palmolive Company | Dental prophylactic paste |
| EP0055109A3 (en) * | 1980-12-24 | 1983-05-11 | Warner-Lambert Company | Anticaries composition |
| WO2005014792A2 (en) * | 2003-08-08 | 2005-02-17 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Preservation of biomaterials with transported preservation agents |
| JP5363697B2 (ja) * | 2005-06-15 | 2013-12-11 | 花王株式会社 | バイオフィルム抑制・除去剤 |
| US20070166242A1 (en) * | 2005-12-19 | 2007-07-19 | Kross Robert D | Oral care product and method for the reduction of dental caries through inclusion of mannan and galactomannan polysaccharides in dentifrice formulations |
| WO2009108926A1 (en) | 2008-02-29 | 2009-09-03 | Board Of Regents, The University Of Texas System | Inhibitors of glycolysis useful in the treatment of brain tumors |
| US9149489B2 (en) | 2006-04-27 | 2015-10-06 | Board Of Regents, University Of Texas System | Inhibitors of glycolysis useful in the treatment of brain tumors |
| ES2604700T3 (es) * | 2006-11-10 | 2017-03-08 | Matsutani Chemical Industry Co., Ltd. | Material no cariogénico y agente cariostático que contiene D-sorbosa |
| WO2008093303A2 (en) | 2007-02-01 | 2008-08-07 | The Iams Company | Method for decreasing inflammation and stress in a mammal using glucose antimetaboltes, avocado or avocado extracts |
| US8709521B2 (en) * | 2007-05-22 | 2014-04-29 | The Coca-Cola Company | Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles |
| JP2013501782A (ja) * | 2009-08-12 | 2013-01-17 | コルゲート・パーモリブ・カンパニー | 口腔ケア組成物 |
| KR101333339B1 (ko) * | 2011-12-07 | 2013-11-27 | 영남대학교 산학협력단 | 바이오필름 억제용 조성물 및 억제방법 |
| CN104955462A (zh) * | 2012-11-26 | 2015-09-30 | 阿波罗尼亚保健股份有限公司 | 用于治疗或预防龋齿的组合物、用途和方法 |
-
2014
- 2014-03-13 AU AU2014233917A patent/AU2014233917B2/en active Active
- 2014-03-13 MX MX2015012917A patent/MX378054B/es unknown
- 2014-03-13 BR BR112015023757A patent/BR112015023757A8/pt not_active Application Discontinuation
- 2014-03-13 US US14/777,461 patent/US20160000680A1/en not_active Abandoned
- 2014-03-13 EP EP14717330.6A patent/EP2970350B1/en active Active
- 2014-03-13 WO PCT/US2014/026013 patent/WO2014151567A1/en not_active Ceased
- 2014-03-13 CN CN201480027220.1A patent/CN105377865B/zh active Active
- 2014-03-13 TW TW103109011A patent/TWI511748B/zh active
- 2014-03-17 AR ARP140101228A patent/AR095603A1/es unknown
-
2015
- 2015-09-21 ZA ZA2015/07011A patent/ZA201507011B/en unknown
-
2020
- 2020-05-27 US US16/884,958 patent/US11471394B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| TW201513890A (zh) | 2015-04-16 |
| CN105377865A (zh) | 2016-03-02 |
| US20160000680A1 (en) | 2016-01-07 |
| WO2014151567A1 (en) | 2014-09-25 |
| EP2970350B1 (en) | 2020-09-09 |
| TWI511748B (zh) | 2015-12-11 |
| CN105377865B (zh) | 2019-03-19 |
| ZA201507011B (en) | 2017-11-29 |
| MX2015012917A (es) | 2016-10-14 |
| MX378054B (es) | 2025-03-10 |
| US20200289393A1 (en) | 2020-09-17 |
| US11471394B2 (en) | 2022-10-18 |
| BR112015023757A2 (pt) | 2017-07-18 |
| AU2014233917A1 (en) | 2015-11-05 |
| EP2970350A1 (en) | 2016-01-20 |
| AU2014233917B2 (en) | 2016-09-15 |
| BR112015023757A8 (pt) | 2020-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |