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AR088047A1 - Composicion farmaceutica que comprende a los fitocannabinoides cannabidivarina (cbdv) y cannabidiol (cbd) - Google Patents

Composicion farmaceutica que comprende a los fitocannabinoides cannabidivarina (cbdv) y cannabidiol (cbd)

Info

Publication number
AR088047A1
AR088047A1 ARP120103556A ARP120103556A AR088047A1 AR 088047 A1 AR088047 A1 AR 088047A1 AR P120103556 A ARP120103556 A AR P120103556A AR P120103556 A ARP120103556 A AR P120103556A AR 088047 A1 AR088047 A1 AR 088047A1
Authority
AR
Argentina
Prior art keywords
cbd
cbdv
cannabidivarine
cannabidiol
pharmaceutical composition
Prior art date
Application number
ARP120103556A
Other languages
English (en)
Inventor
Whalley Benjamin
Williams Claire
Stephens Gary
Original Assignee
Gw Pharma Ltd
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gw Pharma Ltd, Otsuka Pharma Co Ltd filed Critical Gw Pharma Ltd
Publication of AR088047A1 publication Critical patent/AR088047A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Composición farmacéutica que comprende o que consiste esencialmente de los fitocannabinoides cannabidivarina (CBDV) y cannabidiol (CBD). Su uso en el tratamiento de condiciones neurológicas, caracterizadas por hiperexcitabilidad del sistema nervioso central, convulsiones o ataques convulsivos tal como sucede en la epilepsia. Preferiblemente, el CBDV y el CBD están presentes con al menos un componente no cannabinoide de cannabis tal como uno o más terpenos o una fracción de terpenos. Más particularmente, la composición comprende además uno o más compuestos tipo cannabicromeno. En particular, la variante cannabicromeno propilo (CBCV) y/o cannabicromeno (CBC). Aún más particularmente, la composición no contiene o no contiene sustancialmente otros cannabinoides, incluyendo en particular tetrahidrocannabinol (THC) y tetrahidrocannabivarina (THCV), que normalmente estarían presentes en cantidades significativas en los quimiotipos de cannabis cultivados para contener una cantidad significativa de CBDV y/o CBD.
ARP120103556A 2011-09-29 2012-09-26 Composicion farmaceutica que comprende a los fitocannabinoides cannabidivarina (cbdv) y cannabidiol (cbd) AR088047A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1116789.7A GB2495118B (en) 2011-09-29 2011-09-29 A pharmaceutical composition comprising the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD)

Publications (1)

Publication Number Publication Date
AR088047A1 true AR088047A1 (es) 2014-05-07

Family

ID=44994178

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120103556A AR088047A1 (es) 2011-09-29 2012-09-26 Composicion farmaceutica que comprende a los fitocannabinoides cannabidivarina (cbdv) y cannabidiol (cbd)

Country Status (19)

Country Link
US (3) US10729665B2 (es)
EP (2) EP3821885B1 (es)
JP (1) JP6326695B2 (es)
KR (1) KR102107715B1 (es)
CN (2) CN103826621A (es)
AR (1) AR088047A1 (es)
AU (1) AU2012314129B2 (es)
BR (1) BR112014007519A8 (es)
CA (1) CA2845677C (es)
CO (1) CO6900149A2 (es)
EA (1) EA029697B1 (es)
GB (2) GB2495118B (es)
IL (2) IL231701B (es)
MX (1) MX367758B (es)
MY (1) MY171310A (es)
PH (1) PH12014500452A1 (es)
SG (3) SG10202103035YA (es)
TW (1) TWI577373B (es)
WO (1) WO2013045891A1 (es)

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US12121499B2 (en) 2024-10-22
CO6900149A2 (es) 2014-03-20
CN108354914A (zh) 2018-08-03
US20220387347A1 (en) 2022-12-08
CA2845677A1 (en) 2013-04-04
CN103826621A (zh) 2014-05-28
MY171310A (en) 2019-10-08
EA029697B1 (ru) 2018-05-31
PH12014500452A1 (en) 2014-04-14
KR20140069102A (ko) 2014-06-09

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