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AR086772A1 - Variantes del promotor del gen gap que codifica gliceraldehido-3-fosfato deshidrogenasa - Google Patents

Variantes del promotor del gen gap que codifica gliceraldehido-3-fosfato deshidrogenasa

Info

Publication number
AR086772A1
AR086772A1 ARP120102302A ARP120102302A AR086772A1 AR 086772 A1 AR086772 A1 AR 086772A1 AR P120102302 A ARP120102302 A AR P120102302A AR P120102302 A ARP120102302 A AR P120102302A AR 086772 A1 AR086772 A1 AR 086772A1
Authority
AR
Argentina
Prior art keywords
gliceraldehido
codifying
variants
gap
microorganism
Prior art date
Application number
ARP120102302A
Other languages
English (en)
Inventor
Reth Alexander
Dra Bathe Brigitte
Hans Stephan
Dr Claes Wilfried
Original Assignee
Evonik Degussa Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Degussa Gmbh filed Critical Evonik Degussa Gmbh
Publication of AR086772A1 publication Critical patent/AR086772A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Donde el microorganismo es una bacteria del género Corynebacterium. Reivindicación 1: Un polinucleótido aislado que tiene actividad de promotor, caracterizado porque comprende un polinucleótido que tiene la secuencia de nucleótidos que se establece en la SEQ ID Nº 3 o SEQ ID Nº 34. Reivindicación 12: Un vector caracterizado porque comprende el polinucleótido de acuerdo con cualquiera de las reivindicaciones 1 a 11. Reivindicación 13: Un microorganismo caracterizado porque comprende el polinucleótido de acuerdo con cualquiera de las reivindicaciones 1 a 11. Reivindicación 20: Un proceso para preparar un producto químico fino, caracterizado porque comprende los pasos de: a) fermentar un microorganismo definido en cualquiera de las reivindicaciones 13 a 19 en un medio de fermentación para formar un caldo de fermentación, y b) acumular el producto químico fino en el caldo de fermentación de a) y/o en las células del microorganismo.
ARP120102302A 2011-06-28 2012-06-27 Variantes del promotor del gen gap que codifica gliceraldehido-3-fosfato deshidrogenasa AR086772A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102011118019A DE102011118019A1 (de) 2011-06-28 2011-06-28 Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens

Publications (1)

Publication Number Publication Date
AR086772A1 true AR086772A1 (es) 2014-01-22

Family

ID=46319790

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120102302A AR086772A1 (es) 2011-06-28 2012-06-27 Variantes del promotor del gen gap que codifica gliceraldehido-3-fosfato deshidrogenasa

Country Status (12)

Country Link
US (3) US8912313B2 (es)
EP (1) EP2726615B1 (es)
CN (1) CN103635578B (es)
AR (1) AR086772A1 (es)
BR (1) BR112013032605B1 (es)
DE (1) DE102011118019A1 (es)
DK (1) DK2726615T3 (es)
ES (1) ES2624926T3 (es)
MX (1) MX345172B (es)
RU (1) RU2014102474A (es)
TW (1) TW201315808A (es)
WO (1) WO2013000827A1 (es)

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US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
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CN113201539B (zh) * 2021-03-03 2022-09-06 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
CN115322990B (zh) * 2021-05-10 2024-09-20 中国科学院天津工业生物技术研究所 具有启动子活性的多核苷酸及其在生产目标化合物中的用途
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Also Published As

Publication number Publication date
WO2013000827A1 (de) 2013-01-03
DE102011118019A1 (de) 2013-01-03
EP2726615A1 (de) 2014-05-07
ES2624926T3 (es) 2017-07-18
US8912313B2 (en) 2014-12-16
US20130004999A1 (en) 2013-01-03
US20150056666A1 (en) 2015-02-26
MX2013014538A (es) 2014-02-19
MX345172B (es) 2017-01-19
CN103635578A (zh) 2014-03-12
DK2726615T3 (en) 2017-05-22
RU2014102474A (ru) 2015-08-10
TW201315808A (zh) 2013-04-16
US9045762B2 (en) 2015-06-02
US9074229B2 (en) 2015-07-07
CN103635578B (zh) 2016-04-20
BR112013032605A2 (pt) 2017-01-24
US20150140614A1 (en) 2015-05-21
BR112013032605B1 (pt) 2020-10-27
EP2726615B1 (de) 2017-03-01

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