AR076778A1 - Composiciones orales que contienen compuestos de poliguanidinio y metodos de preparacion y uso de las mismas - Google Patents
Composiciones orales que contienen compuestos de poliguanidinio y metodos de preparacion y uso de las mismasInfo
- Publication number
- AR076778A1 AR076778A1 ARP100101708A ARP100101708A AR076778A1 AR 076778 A1 AR076778 A1 AR 076778A1 AR P100101708 A ARP100101708 A AR P100101708A AR P100101708 A ARP100101708 A AR P100101708A AR 076778 A1 AR076778 A1 AR 076778A1
- Authority
- AR
- Argentina
- Prior art keywords
- denotes
- composition according
- oral
- group
- radical
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 10
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- -1 alkyl radical Chemical class 0.000 abstract 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 210000000214 mouth Anatomy 0.000 abstract 3
- 229920006395 saturated elastomer Polymers 0.000 abstract 3
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 208000002925 dental caries Diseases 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 150000003568 thioethers Chemical class 0.000 abstract 2
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical compound NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 239000004202 carbamide Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 235000015218 chewing gum Nutrition 0.000 abstract 1
- 229940112822 chewing gum Drugs 0.000 abstract 1
- 201000002170 dentin sensitivity Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000000981 epithelium Anatomy 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 235000013305 food Nutrition 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000003232 mucoadhesive effect Effects 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 229920000768 polyamine Polymers 0.000 abstract 1
- 125000003367 polycyclic group Polymers 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/16—Fluorine compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Modificacion de materiales basados en poliamina para formar compuestos de poliguanidina que son utiles por sus propiedades antimicrobianas, contra la caries y mucoadhesivas. También métodos para la prevencion o tratamiento de las caries y la enfermedad periodental que incluyen la administracion de una cantidad efectiva desde el punto de vista terapéutico de una composicion oral que contiene un compuesto de poliguanidina en una cavidad oral. Reivindicacion 1: Una composicion oral, caracterizada porque comprende: a) un compuesto de poliguanidina de formula (1), en la cual: X denota un contraion; Z es CH o N; R1, R2 y R3 son cada uno independientemente un hidrogeno un radical alquilo C1-16 lineal o ramificado, saturado o no saturado, opcionalmente hidroxilado; A denota un radical alquileno C1-16 lineal o ramificado, saturado o no saturado, opcionalmente hidroxilado; o A denota un radical alquileno C1-16 lineal o ramificado, saturado o no saturado, opcionalmente sustituido con por lo menos un radical que se selecciona del grupo que consiste de: un radical hidroxilo, carboxilo o carboxilato o un halogeno; el radical alquileno contiene opcionalmente por lo menos un grupo funcional que se selecciona del grupo que consiste de: una amina, éter, tioéter, éster, amida, carbamato, urea, arilo C6 o anillo ciclanilo C3-8 opcionalmente sustituido con un alquilo C1-8, hidroxilo o halogeno; o A denota uno o más arilo C6 o C7 o anillos ciclanilo C5-7 no sustituidos o sustituidos con un alquilo C1-8, un grupo hidroxilo o un halogeno; o A denota un poliarilo C10-14 o cadena de policiclanilo C6-10 que puede ser interrumpida con por lo menos un grupo funcional que se selecciona del grupo que consiste de: un radical alquileno C1-8, amina, amida, éter, tioéter, átomo de hidrogeno, carbamato o urea; n denota un numero entero entre 2 y 5.000; y b) un portador aceptable oralmente. Reivindicacion 2: La composicion de acuerdo con la reivindicacion 1, caracterizada porque dicho contraion es bicarbonato (HCO3-). Reivindicacion 3: La composicion de acuerdo con la reivindicacion 1, caracterizada porque comprende además una sal de calcio. Reivindicacion 6: La composicion de acuerdo con la reivindicacion 1, caracterizada porque comprende además una fuente de fosforo. Reivindicacion 8: La composicion de acuerdo con la reivindicacion 1, caracterizada porque la composicion oral es un producto para el cuidado dental, un producto alimenticio y goma de masticar. Reivindicacion 17: Un método para la fijacion de un ingrediente activo a los tejidos epiteliales orales, caracterizado porque comprende la administracion de una cantidad efectiva desde el punto de vista terapéutico de la composicion oral de acuerdo con la reivindicacion 1 en una cavidad oral. Reivindicacion 20: Un método para el tratamiento o prevencion de la sensibilidad de la dentina, caracterizado porque comprende la administracion de una cantidad efectiva desde el punto de vista terapéutico de la composicion oral de acuerdo con la reivindicacion 1 en una cavidad oral.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2009/044349 WO2010134904A1 (en) | 2009-05-18 | 2009-05-18 | Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR076778A1 true AR076778A1 (es) | 2011-07-06 |
Family
ID=41328739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100101708A AR076778A1 (es) | 2009-05-18 | 2010-05-17 | Composiciones orales que contienen compuestos de poliguanidinio y metodos de preparacion y uso de las mismas |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8758729B2 (es) |
| EP (1) | EP2432444B1 (es) |
| JP (1) | JP5782429B2 (es) |
| CN (1) | CN102427795A (es) |
| AR (1) | AR076778A1 (es) |
| AU (1) | AU2009346357B2 (es) |
| BR (1) | BRPI0924734A2 (es) |
| CA (1) | CA2760130C (es) |
| MX (1) | MX2011011486A (es) |
| MY (1) | MY158777A (es) |
| RU (1) | RU2505280C2 (es) |
| SG (1) | SG175785A1 (es) |
| TW (2) | TW201615199A (es) |
| WO (1) | WO2010134904A1 (es) |
| ZA (1) | ZA201107847B (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0707692B1 (pt) | 2006-02-09 | 2021-03-09 | The University Of Melbourne | uso de fosfato de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres ou de fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeo em combinação com íons fluoreto livres na fabricação de composições dentais |
| MX2011011486A (es) | 2009-05-18 | 2011-11-18 | Colgate Palmolive Co | Composiciones orales que contienen compuestos de poliguandino y metodos de preparacion y uso de las mismas. |
| CN102844662B (zh) | 2010-03-03 | 2015-04-29 | 3M创新有限公司 | 配体胍基官能化聚合物 |
| MX378581B (es) | 2013-07-23 | 2025-03-10 | Univ Melbourne | Composiciones y metodos para la mineralizacion dental. |
| US10912722B2 (en) | 2013-12-24 | 2021-02-09 | The University Of Melbourne | Stabilized stannous compositions |
| WO2015161860A1 (en) * | 2014-04-25 | 2015-10-29 | Frank Flechsig | Improved biocide compositions based on calcium fluoride as well as uses thereof |
| JP6751027B2 (ja) * | 2014-07-11 | 2020-09-02 | コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． | 非晶質リン酸カルシウムを供給する口腔ケア処方システム |
| US20180008518A1 (en) * | 2014-12-24 | 2018-01-11 | The University Of Melbourne | Mineralization fluoride compositions |
| AU2017245246A1 (en) * | 2016-03-29 | 2018-10-11 | Safewhite, Inc. | Polyelectrolyte dental adhesives for whitening teeth and teeth components |
| DE102016205950A1 (de) * | 2016-04-08 | 2017-10-12 | Dietrich Seidel | Mittel zur Verwendung bei entzündlichen Zuständen der Schleimhäute |
| MX370168B (es) | 2016-08-11 | 2019-12-04 | Colgate Palmolive Co | Composiciones para el cuidado bucal. |
| RU2722183C1 (ru) * | 2016-10-20 | 2020-05-28 | Колгейт-Палмолив Компани | Противомикробные композиции для ухода за полостью рта или ее очистки и способы получения полимеров и покрытий, препятствующих прикреплению |
| WO2018085744A1 (en) | 2016-11-07 | 2018-05-11 | 3M Innovative Properties Company | Dental retraction composition with guanidinyl-containing polymer |
| JP7142943B2 (ja) | 2017-03-14 | 2022-09-28 | ザ ユニバーシティー オブ メルボルン | 歯肉炎の処置 |
| CN110475539A (zh) | 2017-03-14 | 2019-11-19 | 墨尔本大学 | 用于治疗敏感症的复合物 |
| US20200368005A1 (en) * | 2017-09-29 | 2020-11-26 | Safewhite, Inc. | Polyelectrolyte dental coatings |
| US10426576B2 (en) * | 2017-10-12 | 2019-10-01 | King Abdulaziz University | Method for debonding of orthodontic metal brackets with eugenol emulgel |
| WO2020047662A1 (en) | 2018-09-05 | 2020-03-12 | Ir Scientific Inc. | Glass composition |
| US11033485B1 (en) | 2019-05-16 | 2021-06-15 | Shear Kershman Laboratories, Inc. | Dental care system containing anti-tartar and anti-plaque actives |
| US11007216B2 (en) | 2019-08-05 | 2021-05-18 | International Business Machines Corporation | Combination therapy to achieve enhanced antimicrobial activity |
| US11028264B2 (en) * | 2019-08-05 | 2021-06-08 | International Business Machines Corporation | Polylysine polymers with antimicrobial and/or anticancer activity |
| RU2732291C1 (ru) * | 2020-02-13 | 2020-09-15 | Открытое акционерное общество "Фармстандарт-Лексредства" (ОАО "Фармстандарт-Лексредства") | Лекарственный препарат на основе травы алтея лекарственного для лечения простудных и острых респираторных заболеваний |
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-
2009
- 2009-05-18 MX MX2011011486A patent/MX2011011486A/es active IP Right Grant
- 2009-05-18 BR BRPI0924734A patent/BRPI0924734A2/pt active Search and Examination
- 2009-05-18 CN CN2009801594451A patent/CN102427795A/zh active Pending
- 2009-05-18 AU AU2009346357A patent/AU2009346357B2/en active Active
- 2009-05-18 JP JP2012511793A patent/JP5782429B2/ja not_active Expired - Fee Related
- 2009-05-18 US US13/266,930 patent/US8758729B2/en active Active
- 2009-05-18 EP EP09789704.5A patent/EP2432444B1/en active Active
- 2009-05-18 WO PCT/US2009/044349 patent/WO2010134904A1/en not_active Ceased
- 2009-05-18 RU RU2011151628/15A patent/RU2505280C2/ru not_active IP Right Cessation
- 2009-05-18 CA CA2760130A patent/CA2760130C/en not_active Expired - Fee Related
- 2009-05-18 MY MYPI2011005028A patent/MY158777A/en unknown
- 2009-05-18 SG SG2011078086A patent/SG175785A1/en unknown
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2010
- 2010-05-17 TW TW104132098A patent/TW201615199A/zh unknown
- 2010-05-17 AR ARP100101708A patent/AR076778A1/es unknown
- 2010-05-17 TW TW099115608A patent/TWI522104B/zh not_active IP Right Cessation
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2011
- 2011-10-26 ZA ZA2011/07847A patent/ZA201107847B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010134904A1 (en) | 2010-11-25 |
| SG175785A1 (en) | 2011-12-29 |
| EP2432444B1 (en) | 2017-08-23 |
| TW201106954A (en) | 2011-03-01 |
| US8758729B2 (en) | 2014-06-24 |
| AU2009346357B2 (en) | 2012-11-29 |
| JP5782429B2 (ja) | 2015-09-24 |
| CA2760130A1 (en) | 2010-11-25 |
| JP2012527456A (ja) | 2012-11-08 |
| MY158777A (en) | 2016-11-15 |
| CN102427795A (zh) | 2012-04-25 |
| TWI522104B (zh) | 2016-02-21 |
| CA2760130C (en) | 2016-11-08 |
| AU2009346357A1 (en) | 2011-11-17 |
| MX2011011486A (es) | 2011-11-18 |
| TW201615199A (zh) | 2016-05-01 |
| US20120045400A1 (en) | 2012-02-23 |
| RU2505280C2 (ru) | 2014-01-27 |
| EP2432444A1 (en) | 2012-03-28 |
| ZA201107847B (en) | 2014-03-26 |
| BRPI0924734A2 (pt) | 2016-01-26 |
| RU2011151628A (ru) | 2013-06-27 |
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