[go: up one dir, main page]

AR075881A1 - Composicion farmaceutica.metodo de preparacion - Google Patents

Composicion farmaceutica.metodo de preparacion

Info

Publication number
AR075881A1
AR075881A1 ARP100100866A ARP100100866A AR075881A1 AR 075881 A1 AR075881 A1 AR 075881A1 AR P100100866 A ARP100100866 A AR P100100866A AR P100100866 A ARP100100866 A AR P100100866A AR 075881 A1 AR075881 A1 AR 075881A1
Authority
AR
Argentina
Prior art keywords
pharmaceutical composition
composition according
filler
different
acceptable salt
Prior art date
Application number
ARP100100866A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of AR075881A1 publication Critical patent/AR075881A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Reivindicacion 1: Una composicion farmacéutica, la cual comprende: a) una cantidad terapéuticamente efectiva de Alisquireno o una sal farmacéuticamente aceptable del mismo, b) un relleno; y c) uno o más, por ejemplo, de uno a tres rellenos diferentes del relleno b), e independientemente seleccionados a partir de: c1) alditoles; c2) mono-, di-, tri-, y polisacáridos; y c3) un relleno que tenga una densidad a granel asentada en el intervalo de 0.5 a 1.5 g/cm3, y en el entendido de que, si está comprendida la Indigotina Lake en la composicion, no está en una cantidad de 0.13, 0.2, 0.25 o 0.5 miligramos por dosis unitaria. Reivindicacion 6: La composicion farmacéutica de acuerdo con cualquiera de las reivindicaciones anteriores, en la forma de una tableta de dos capas, la cual comprende una capa que contiene a la composicion farmacéutica de acuerdo con cualquiera de las reivindicaciones anteriores, y una segunda capa que comprende un principio farmacéuticamente activo d) que es diferente del componente a). Reivindicacion 7: La composicion farmacéutica de acuerdo con la reivindicacion 6, en donde el principio farmacéuticamente activo d) que es diferente del componente a) es Valsartan o una sal farmacéuticamente aceptable del mismo. Reivindicacion 12: El uso de la composicion farmacéutica de acuerdo con cualquiera de las reivindicaciones anteriores, para el tratamiento de hipertension, insuficiencia cardíaca congestiva, angina, infarto de miocardio, arterioesclerosis, nefropatía diabética, miopatía cardíaca diabética, insuficiencia renal, enfermedad vascular periférica, hipertrofia de ventrículo izquierdo, disfuncion cognitiva, embolia, dolor de cabeza, e insuficiencia cardíaca cronica, en particular hipertension.
ARP100100866A 2009-03-20 2010-03-18 Composicion farmaceutica.metodo de preparacion AR075881A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16188309P 2009-03-20 2009-03-20

Publications (1)

Publication Number Publication Date
AR075881A1 true AR075881A1 (es) 2011-05-04

Family

ID=42245650

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100100866A AR075881A1 (es) 2009-03-20 2010-03-18 Composicion farmaceutica.metodo de preparacion

Country Status (12)

Country Link
US (1) US20120003308A1 (es)
EP (1) EP2408433A1 (es)
JP (1) JP2012520892A (es)
KR (1) KR20110129482A (es)
CN (1) CN102361633A (es)
AR (1) AR075881A1 (es)
AU (1) AU2010226615A1 (es)
BR (1) BRPI1009131A2 (es)
CA (1) CA2753221A1 (es)
MX (1) MX2011009844A (es)
TW (1) TW201038299A (es)
WO (1) WO2010107966A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2011142081A (ru) * 2009-03-20 2013-04-27 Новартис Аг Галеновые фиксированные комбинации валсартана и алискирена

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY119161A (en) 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
AR048431A1 (es) * 2004-03-17 2006-04-26 Novartis Ag Formulaciones galenicas de compuestos organicos
MY146830A (en) * 2005-02-11 2012-09-28 Novartis Ag Combination of organic compounds
WO2009045795A2 (en) * 2007-09-28 2009-04-09 Novartis Ag Galenical formulations of aliskiren and valsartan

Also Published As

Publication number Publication date
EP2408433A1 (en) 2012-01-25
US20120003308A1 (en) 2012-01-05
BRPI1009131A2 (pt) 2016-03-01
JP2012520892A (ja) 2012-09-10
MX2011009844A (es) 2011-09-29
WO2010107966A1 (en) 2010-09-23
AU2010226615A1 (en) 2011-09-15
CA2753221A1 (en) 2010-09-23
KR20110129482A (ko) 2011-12-01
CN102361633A (zh) 2012-02-22
TW201038299A (en) 2010-11-01

Similar Documents

Publication Publication Date Title
AR075179A1 (es) Formulaciones galenicas de compuestos organicos que comprenden alisquireno
AR066168A1 (es) Formulaciones galenicas de compuestos organicos
JP2021509912A5 (es)
CO6531458A2 (es) Nuevos compuestos de espiropiperidina
CL2011000798A1 (es) Uso de etexilato de dabigatran o una sal del mismo para preparar un medicamento util para la prevencion del ictus en pacientes que padecen fibrilacion auricular.
ECSP12011930A (es) Nuevos compuestos de espiropiperidina
CL2011001848A1 (es) Compuestos derivados de pirimidina fusionada a un heterociclo de 5 miembros; antagonista del receptor de angiotensina ii, agonista del receptor de proliferador de peroxisomas; composicion farmaceutica; y uso de los compuestos en el tratamiento de enfermedades circulatorias tales como hipertension, enfermedad cardiaca, arteriosclerosis, entre otras.
EA201071204A1 (ru) Применение дронедарона для приготовления лекарственного средства для применения в предотвращении госпитализации в кардиологическое отделение или смертности
DOP2023000251A (es) Compuestos oligoméricos que inhiben la expresión de hsd17b13
PE20141049A1 (es) Composicion farmaceutica antihipertensiva
Sardar et al. Antiarrhythmic drug therapy for atrial fibrillation
JP2013166781A5 (es)
JP2009537554A5 (es)
JP2016512817A5 (es)
AR077018A1 (es) Un comprimido de dosis fija del antagonista del receptor de la trombina y el clopidogrel.
RU2016112257A (ru) Композиция для лечения гипертензии и/или фиброза
RU2015143475A (ru) Продукт и способ лечения диареи
MX2016007682A (es) Composicion farmaceutica que comprende ivabradina amorfa.
CO6311083A2 (es) 4-((1r,3s)-6-cloro-3-fenilindan-1-il)-1,2,2-trimetilpiperazina para el tratamiento de la disfunción cognitiva
AR084882A1 (es) Compuesto de 1-azabiciclo[2.2.2]octano y usos para el tratamiento de esquizofrenia
AR075881A1 (es) Composicion farmaceutica.metodo de preparacion
UA100883C2 (ru) Применение дронедарона для получения лекарственного средства для лечения пациентов с аритмией и с повышенным уровнем креатинина в результате введения дронедарона
AR075988A1 (es) Compuesto de piridiloxi - pirrolidina inhibidor de recaptacion de serotonina y norepinefrina, composicion farmaceutica que lo comprende y su uso para la manufactura de un medicamento util para el tratamiento de dolor cronico
CL2007001837A1 (es) Forma de dosificacion oral solida que comprende alisquireno, hidroclorotiazida y un relleno hidrofilico; proceso de preparacion; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca congestiva, infarto de miocardio,
AR068539A1 (es) Formulaciones galenicas de compuestos organicos

Legal Events

Date Code Title Description
FB Suspension of granting procedure