AR067887A1 - Composicion medica con contenido de rebamipide - Google Patents
Composicion medica con contenido de rebamipideInfo
- Publication number
- AR067887A1 AR067887A1 ARP080103471A ARP080103471A AR067887A1 AR 067887 A1 AR067887 A1 AR 067887A1 AR P080103471 A ARP080103471 A AR P080103471A AR P080103471 A ARP080103471 A AR P080103471A AR 067887 A1 AR067887 A1 AR 067887A1
- Authority
- AR
- Argentina
- Prior art keywords
- medical composition
- salt
- rebamipide
- content
- arginine
- Prior art date
Links
- ALLWOAVDORUJLA-UHFFFAOYSA-N Rebamipida Chemical compound C=1C(=O)NC2=CC=CC=C2C=1CC(C(=O)O)NC(=O)C1=CC=C(Cl)C=C1 ALLWOAVDORUJLA-UHFFFAOYSA-N 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 229950004535 rebamipide Drugs 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 abstract 5
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 abstract 2
- 229930064664 L-arginine Natural products 0.000 abstract 2
- 235000014852 L-arginine Nutrition 0.000 abstract 2
- 235000019658 bitter taste Nutrition 0.000 abstract 2
- 235000003599 food sweetener Nutrition 0.000 abstract 2
- 239000003765 sweetening agent Substances 0.000 abstract 2
- 244000228451 Stevia rebaudiana Species 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- HELXLJCILKEWJH-NCGAPWICSA-N rebaudioside A Chemical compound O([C@H]1[C@H](O)[C@@H](CO)O[C@H]([C@@H]1O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HELXLJCILKEWJH-NCGAPWICSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Preparacion farmacéutica en la cual se reduce la expresion de la amargura. La composicion médica de la presente contiene rebamipide, o una sal del mismo, y L-arginina, o una sal de la misma. La forma de realizacion preferida de la composicion médica de la presente contiene rebamipide, o una sal del mismo, y L-arginina, o una sal de la misma, junto con al menos un edulcorante seleccionado del grupo que consistente en taumatina, stevia y extractos del fruto de luohan. Al agregar dicho edulcorante, es posible reducir sensiblemente la amargura atribuible al rebamipide, o a una sal del mismo, de la composicion médica.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007209284 | 2007-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR067887A1 true AR067887A1 (es) | 2009-10-28 |
Family
ID=39884986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080103471A AR067887A1 (es) | 2007-08-10 | 2008-08-08 | Composicion medica con contenido de rebamipide |
Country Status (7)
| Country | Link |
|---|---|
| JP (2) | JP5328789B2 (es) |
| KR (1) | KR101551506B1 (es) |
| CN (1) | CN101778626B (es) |
| AR (1) | AR067887A1 (es) |
| MY (1) | MY157582A (es) |
| TW (1) | TW200918060A (es) |
| WO (1) | WO2009022674A1 (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103429224A (zh) * | 2011-03-24 | 2013-12-04 | 大塚制药株式会社 | 用于治疗口腔疾病的包含瑞巴派特的药物组合物 |
| JP5756727B2 (ja) * | 2011-09-30 | 2015-07-29 | ハウス食品グループ本社株式会社 | 顆粒 |
| WO2014021637A1 (ko) * | 2012-07-31 | 2014-02-06 | 가톨릭대학교 산학협력단 | 레바미피드를 유효성분으로 포함하는 고지혈증 및 이와 관련된 질환의 예방 또는 치료용 조성물 |
| MY172574A (en) * | 2012-12-28 | 2019-12-03 | Kao Corp | Dicaffeoylquinic acid-containing drink |
| JP6468919B2 (ja) * | 2014-03-31 | 2019-02-13 | 富士フイルム富山化学株式会社 | セファロスポリンエステルを含む粒状固形製剤 |
| KR20170039347A (ko) * | 2015-10-01 | 2017-04-11 | 삼진제약주식회사 | 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법 |
| US20170295834A1 (en) * | 2015-11-25 | 2017-10-19 | Alexander LaCroix | All-Natural Bitterness-Reducing Flavor System |
| CN110167551B (zh) | 2016-12-28 | 2022-06-14 | 富士胶片富山化学株式会社 | 医药组合物 |
| JP7011300B2 (ja) * | 2017-12-19 | 2022-02-10 | 株式会社島田製薬 | ＨＭＢＣａ含有顆粒の製造方法、及びサプリメント |
| KR101923519B1 (ko) * | 2018-06-26 | 2019-02-27 | 대우제약 주식회사 | 레바미피드를 함유하는 안구 건조증 치료용 수용성 다회용 점안제 조성물 및 이의 가용화 및 안정화 방법 |
| JP7698962B2 (ja) * | 2021-03-19 | 2025-06-26 | 三栄源エフ・エフ・アイ株式会社 | 不快風味のマスキング方法 |
| KR20230090184A (ko) | 2021-12-14 | 2023-06-21 | 메디케어제약 주식회사 | 에스오메프라졸 및 레바미피드를 포함하는 약제학적 복합제제 |
| KR20230090185A (ko) | 2021-12-14 | 2023-06-21 | 메디케어제약 주식회사 | 위 점막 병변을 동반한 류마티스 관절염을 치료하는 약제학적 복합제제 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0674515T3 (da) * | 1993-10-21 | 1999-12-20 | Otsuka Pharma Co Ltd | Anvendelse af carbostyrilderivater til fremstilling af et medikament til inhibering af interleukin-8 |
| JPH10306038A (ja) * | 1997-05-07 | 1998-11-17 | Taisho Pharmaceut Co Ltd | ブロムヘキシン含有液剤 |
| JP3466921B2 (ja) * | 1998-06-03 | 2003-11-17 | 大塚製薬株式会社 | 味マスキング医薬製剤 |
| JP3417857B2 (ja) * | 1998-12-11 | 2003-06-16 | 日清オイリオ株式会社 | 調味料 |
| KR20040104020A (ko) * | 2003-06-02 | 2004-12-10 | 진양제약주식회사 | 신규 레바미피드 리지네이트와 레바미피드 아르기니네이트및 이 신규 레바미피드 리지네이트와 레바미피드아르기니네이트를 유효성분으로 함유하는 약학적 제제 |
| JP4244715B2 (ja) * | 2003-06-12 | 2009-03-25 | 株式会社ノエビア | 薬味飲料 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
| JP2005312305A (ja) * | 2004-04-27 | 2005-11-10 | Goodoo Kasei Kk | 健康剤 |
| JP4713104B2 (ja) * | 2004-08-04 | 2011-06-29 | ファイザー株式会社 | アジスロマイシン類を有効成分とする苦味が抑制された安定な組成物 |
| WO2006114918A1 (ja) * | 2005-04-22 | 2006-11-02 | Yaizu Suisankagaku Industry Co., Ltd. | 塩化カリウム含有飲食品の呈味改善剤、塩化カリウム含有飲食品の製造方法、及び該製造方法によって得られた塩化カリウム含有飲食品 |
| JP4881268B2 (ja) * | 2006-09-25 | 2012-02-22 | あすか製薬株式会社 | 苦味が抑制された経口製剤 |
-
2008
- 2008-08-05 JP JP2010519618A patent/JP5328789B2/ja not_active Expired - Fee Related
- 2008-08-05 MY MYPI2010000374A patent/MY157582A/en unknown
- 2008-08-05 KR KR1020107005185A patent/KR101551506B1/ko not_active Expired - Fee Related
- 2008-08-05 WO PCT/JP2008/064385 patent/WO2009022674A1/en not_active Ceased
- 2008-08-05 CN CN200880102776.7A patent/CN101778626B/zh not_active Expired - Fee Related
- 2008-08-08 TW TW097130221A patent/TW200918060A/zh unknown
- 2008-08-08 AR ARP080103471A patent/AR067887A1/es unknown
-
2013
- 2013-05-17 JP JP2013105172A patent/JP2013177418A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP5328789B2 (ja) | 2013-10-30 |
| JP2010535757A (ja) | 2010-11-25 |
| KR20100051850A (ko) | 2010-05-18 |
| JP2013177418A (ja) | 2013-09-09 |
| WO2009022674A1 (en) | 2009-02-19 |
| KR101551506B1 (ko) | 2015-09-08 |
| CN101778626B (zh) | 2014-05-07 |
| TW200918060A (en) | 2009-05-01 |
| MY157582A (en) | 2016-06-30 |
| CN101778626A (zh) | 2010-07-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |