AR059149A1 - Derivados de indoloquinoxalina con actividad anti viral - Google Patents
Derivados de indoloquinoxalina con actividad anti viralInfo
- Publication number
- AR059149A1 AR059149A1 ARP070100274A ARP070100274A AR059149A1 AR 059149 A1 AR059149 A1 AR 059149A1 AR P070100274 A ARP070100274 A AR P070100274A AR P070100274 A ARP070100274 A AR P070100274A AR 059149 A1 AR059149 A1 AR 059149A1
- Authority
- AR
- Argentina
- Prior art keywords
- viral activity
- anti viral
- indoloquinoxaline
- derivatives
- indoloquinoxaline derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Un compuesto de formula (1) en donde R1 se selecciona de H, F, CI, Br, CF3, alcoxi C1-6 y OH; R2 se selecciona de H y alquilo C1-6; n es 1-12; m es 0 o 1; Y se selecciona de CH2, NR3, (NR3R4)+X-, O y S; R3 y R4 son independientemente seleccionados de H y alquilo C1-4 y X se selecciona de aniones aceptables farmacéuticamente. Un método para preparar el compuesto, su uso como un fármaco, y un método de tratamiento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0600134A SE529777C2 (sv) | 2006-01-23 | 2006-01-23 | Nya föreningar och användning därav |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR059149A1 true AR059149A1 (es) | 2008-03-12 |
Family
ID=38287919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070100274A AR059149A1 (es) | 2006-01-23 | 2007-01-22 | Derivados de indoloquinoxalina con actividad anti viral |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US8076341B2 (es) |
| EP (1) | EP1976853B1 (es) |
| JP (1) | JP5190379B2 (es) |
| CN (1) | CN101374845B (es) |
| AR (1) | AR059149A1 (es) |
| AT (1) | ATE506365T1 (es) |
| AU (1) | AU2007206092B2 (es) |
| BR (1) | BRPI0707203C1 (es) |
| CA (1) | CA2637417C (es) |
| CY (1) | CY1112596T1 (es) |
| DE (1) | DE602007014008D1 (es) |
| DK (1) | DK1976853T3 (es) |
| ES (1) | ES2365423T3 (es) |
| HR (1) | HRP20110534T1 (es) |
| IL (1) | IL192820A (es) |
| NZ (1) | NZ569840A (es) |
| PL (1) | PL1976853T3 (es) |
| PT (1) | PT1976853E (es) |
| RS (1) | RS51933B (es) |
| RU (1) | RU2437887C2 (es) |
| SE (1) | SE529777C2 (es) |
| SI (1) | SI1976853T1 (es) |
| WO (1) | WO2007084073A1 (es) |
| ZA (1) | ZA200806315B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE473977T1 (de) | 2008-04-30 | 2010-07-15 | Univ Duisburg Essen | Indolä2,3-bü-, indenä1,2-bü- und indenä2,1- büpyridoä2,3-fü quinoxalin-3-carboxylsäuren und ester, verfahren zu ihrer herstellung und ihre verwendung als antivirus- und antitumormittel |
| EP2489354A1 (en) | 2011-02-18 | 2012-08-22 | Vironova AB | Pharmaceutical formulation of B220 for topical treatment of herpes |
| CN105061432B (zh) * | 2015-07-16 | 2017-09-29 | 河北大学 | 6H‑吲哚[2,3‑b]喹喔啉衍生物、药物组合物及其制备和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8600261D0 (sv) * | 1986-01-21 | 1986-01-21 | Lundblad Leif | Indolokinoxaliner med substituenter i 6-position som innehaller cykliska grupper |
| SE8600260D0 (sv) * | 1986-01-21 | 1986-01-21 | Lundblad Leif | Substituerade indolokinoxaliner |
| SE504862C2 (sv) * | 1994-12-27 | 1997-05-20 | Leif J I Lundblad | Användning av vissa indolo-§2,3b¤-kinoxaliner för framställning av ett läkemedel för skydd av DNA i initieringsfasen och/eller promotionsfasen av karcinogenes och för förhindrande av oxidativ stress i patienter med sjukdomar relaterade till fria radikaler |
| SE527639C2 (sv) * | 2004-06-17 | 2006-05-02 | Oxypharma Ab | Alkylsubstituerade indolokinoxaliner |
-
2006
- 2006-01-23 SE SE0600134A patent/SE529777C2/sv not_active IP Right Cessation
-
2007
- 2007-01-22 HR HR20110534T patent/HRP20110534T1/hr unknown
- 2007-01-22 DE DE602007014008T patent/DE602007014008D1/de active Active
- 2007-01-22 JP JP2008551228A patent/JP5190379B2/ja not_active Expired - Fee Related
- 2007-01-22 CN CN2007800028861A patent/CN101374845B/zh not_active Expired - Fee Related
- 2007-01-22 ES ES07709426T patent/ES2365423T3/es active Active
- 2007-01-22 PT PT07709426T patent/PT1976853E/pt unknown
- 2007-01-22 RS RS20110304A patent/RS51933B/sr unknown
- 2007-01-22 US US12/161,081 patent/US8076341B2/en not_active Expired - Fee Related
- 2007-01-22 AU AU2007206092A patent/AU2007206092B2/en not_active Ceased
- 2007-01-22 CA CA2637417A patent/CA2637417C/en not_active Expired - Fee Related
- 2007-01-22 NZ NZ569840A patent/NZ569840A/en not_active IP Right Cessation
- 2007-01-22 WO PCT/SE2007/050033 patent/WO2007084073A1/en not_active Ceased
- 2007-01-22 BR BRPI0707203A patent/BRPI0707203C1/pt not_active IP Right Cessation
- 2007-01-22 PL PL07709426T patent/PL1976853T3/pl unknown
- 2007-01-22 ZA ZA200806315A patent/ZA200806315B/xx unknown
- 2007-01-22 SI SI200730657T patent/SI1976853T1/sl unknown
- 2007-01-22 EP EP07709426A patent/EP1976853B1/en active Active
- 2007-01-22 AT AT07709426T patent/ATE506365T1/de active
- 2007-01-22 DK DK07709426.6T patent/DK1976853T3/da active
- 2007-01-22 RU RU2008134509/04A patent/RU2437887C2/ru active
- 2007-01-22 AR ARP070100274A patent/AR059149A1/es not_active Application Discontinuation
-
2008
- 2008-07-15 IL IL192820A patent/IL192820A/en active IP Right Grant
-
2011
- 2011-07-18 CY CY20111100698T patent/CY1112596T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |