AR057858A1 - Una composicion inhibidora de la agregacion plaquetaria - Google Patents
Una composicion inhibidora de la agregacion plaquetariaInfo
- Publication number
- AR057858A1 AR057858A1 ARP060104826A ARP060104826A AR057858A1 AR 057858 A1 AR057858 A1 AR 057858A1 AR P060104826 A ARP060104826 A AR P060104826A AR P060104826 A ARP060104826 A AR P060104826A AR 057858 A1 AR057858 A1 AR 057858A1
- Authority
- AR
- Argentina
- Prior art keywords
- amino acid
- acid sequence
- polypeptide
- plaquetary
- agregation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Insects & Arthropods (AREA)
Abstract
Una composicion farmacéutica que comprende al menos un polipéptido de los puntos (a) a (d) siguientes: (a) un polipéptido que comprende la secuencia de aminoácido de la SEQ ID Ns: 1; (b) un polipéptido que comprende una secuencia de aminoácidos que comprende una o más eliminaciones, inserciones, substituciones o adiciones de aminoácidos en la secuencia de aminoácidos del punto (a) anterior y que posee actividad inhibidora de la agregacion plaquetaria y/o actividad inhibidora de la adhesion plaquetaria; (c) un polipéptido que comprende la secuencia de aminoácidos de la SEQ ID Ns: 3; y (d) un polipéptido que comprende una secuencia de aminoácidos que compende una o más eliminaciones, inserciones, substituciones o adiciones de aminoácidos en la secuencia de aminoácidos del punto (c) anterior y que posee actividad inhibidora de la agregacion plaquetaria y/o actividad inhibidora de la adhesion plaquetaria; como componente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005320817 | 2005-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR057858A1 true AR057858A1 (es) | 2007-12-19 |
Family
ID=38005983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060104826A AR057858A1 (es) | 2005-11-04 | 2006-11-03 | Una composicion inhibidora de la agregacion plaquetaria |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8034763B2 (es) |
| EP (2) | EP2077328B1 (es) |
| JP (1) | JP4954204B2 (es) |
| KR (1) | KR101311570B1 (es) |
| CN (2) | CN102911264B (es) |
| AR (1) | AR057858A1 (es) |
| AU (1) | AU2006309543B2 (es) |
| BR (1) | BRPI0618194A2 (es) |
| CA (1) | CA2625106C (es) |
| ES (2) | ES2547380T3 (es) |
| IL (2) | IL188986A0 (es) |
| MY (1) | MY148135A (es) |
| PH (1) | PH12013502021B1 (es) |
| RU (2) | RU2434941C2 (es) |
| SG (1) | SG166817A1 (es) |
| TW (1) | TWI391143B (es) |
| WO (1) | WO2007052841A1 (es) |
| ZA (1) | ZA200801161B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108503689B (zh) * | 2017-07-10 | 2019-12-31 | 昆明医科大学第一附属医院 | 一种抗血小板聚集的多肽km6 |
| CN108503692B (zh) * | 2017-07-10 | 2019-12-31 | 昆明医科大学第一附属医院 | 一种促血小板聚集的多肽pep1 |
| CN110339344B (zh) * | 2019-08-07 | 2022-12-30 | 上海交通大学医学院附属仁济医院 | 核受体Rev-erbα在制备抗血小板药物中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE210679T1 (de) * | 1993-07-01 | 2001-12-15 | Merck Patent Gmbh | Ein inhibitor der collagenstimulierten plättchenaggregation |
| CA2199719A1 (en) * | 1994-09-12 | 1996-03-21 | Christiane Noeske-Jungblut | Process for manufacture of a modified collagen-induced platelet aggregation inhibitor pallidipin |
| RU2192857C1 (ru) * | 2001-04-24 | 2002-11-20 | Институт органической химии им. Н.Д. Зелинского РАН | Ингибитор агрегации тромбоцитов, обладающий антиметастатическим действием |
| JP3648548B2 (ja) * | 2001-10-15 | 2005-05-18 | 国立大学法人三重大学 | 血液凝固阻害活性を有するハマダラカ由来のＡｓ−１蛋白質 |
| JP3837519B2 (ja) | 2002-10-02 | 2006-10-25 | 国立大学法人三重大学 | 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−３蛋白質 |
| JP3837518B2 (ja) | 2002-10-02 | 2006-10-25 | 国立大学法人三重大学 | 血小板凝集阻害活性を有するブラジルサシガメ由来のＴｉ−４蛋白質 |
-
2006
- 2006-10-26 TW TW95139546A patent/TWI391143B/zh not_active IP Right Cessation
- 2006-11-02 SG SG201008077-8A patent/SG166817A1/en unknown
- 2006-11-02 CN CN201210390650.2A patent/CN102911264B/zh not_active Expired - Fee Related
- 2006-11-02 RU RU2008122338/10A patent/RU2434941C2/ru not_active IP Right Cessation
- 2006-11-02 EP EP09153422.2A patent/EP2077328B1/en not_active Not-in-force
- 2006-11-02 US US12/065,701 patent/US8034763B2/en not_active Expired - Fee Related
- 2006-11-02 MY MYPI20080355 patent/MY148135A/en unknown
- 2006-11-02 AU AU2006309543A patent/AU2006309543B2/en not_active Ceased
- 2006-11-02 ES ES06832470.6T patent/ES2547380T3/es active Active
- 2006-11-02 BR BRPI0618194-5A patent/BRPI0618194A2/pt not_active IP Right Cessation
- 2006-11-02 ES ES09153422.2T patent/ES2547404T3/es active Active
- 2006-11-02 JP JP2008519765A patent/JP4954204B2/ja not_active Expired - Fee Related
- 2006-11-02 RU RU2011120138/10A patent/RU2557296C2/ru not_active IP Right Cessation
- 2006-11-02 WO PCT/JP2006/322417 patent/WO2007052841A1/en not_active Ceased
- 2006-11-02 KR KR1020087013445A patent/KR101311570B1/ko not_active Expired - Fee Related
- 2006-11-02 CN CN2006800352979A patent/CN101273128B/zh not_active Expired - Fee Related
- 2006-11-02 ZA ZA200801161A patent/ZA200801161B/xx unknown
- 2006-11-02 CA CA2625106A patent/CA2625106C/en not_active Expired - Fee Related
- 2006-11-02 EP EP06832470.6A patent/EP1943337B1/en not_active Not-in-force
- 2006-11-03 AR ARP060104826A patent/AR057858A1/es unknown
-
2008
- 2008-01-24 IL IL188986A patent/IL188986A0/en unknown
-
2011
- 2011-08-22 US US13/215,004 patent/US8309512B2/en not_active Expired - Fee Related
-
2013
- 2013-09-27 PH PH12013502021A patent/PH12013502021B1/en unknown
- 2013-10-21 IL IL228986A patent/IL228986A0/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |