AR054133A1 - Preparacion recubierta con azucar - Google Patents
Preparacion recubierta con azucarInfo
- Publication number
- AR054133A1 AR054133A1 ARP060102421A ARP060102421A AR054133A1 AR 054133 A1 AR054133 A1 AR 054133A1 AR P060102421 A ARP060102421 A AR P060102421A AR P060102421 A ARP060102421 A AR P060102421A AR 054133 A1 AR054133 A1 AR 054133A1
- Authority
- AR
- Argentina
- Prior art keywords
- sugar
- oxygen
- active ingredient
- preparation
- preparation according
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 5
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000011230 binding agent Substances 0.000 abstract 2
- 150000005846 sugar alcohols Chemical class 0.000 abstract 2
- 238000009495 sugar coating Methods 0.000 abstract 2
- 125000000590 4-methylphenyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1*)C([H])([H])[H] 0.000 abstract 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 abstract 1
- 239000004386 Erythritol Substances 0.000 abstract 1
- UNXHWFMMPAWVPI-UHFFFAOYSA-N Erythritol Natural products OCC(O)C(O)CO UNXHWFMMPAWVPI-UHFFFAOYSA-N 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- 229930195725 Mannitol Natural products 0.000 abstract 1
- 241000978776 Senegalia senegal Species 0.000 abstract 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 abstract 1
- 239000000205 acacia gum Substances 0.000 abstract 1
- 235000010489 acacia gum Nutrition 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 239000011247 coating layer Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 235000019414 erythritol Nutrition 0.000 abstract 1
- UNXHWFMMPAWVPI-ZXZARUISSA-N erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 abstract 1
- 229940009714 erythritol Drugs 0.000 abstract 1
- GWVMLCQWXVFZCN-UHFFFAOYSA-N isoindoline Chemical compound C1=CC=C2CNCC2=C1 GWVMLCQWXVFZCN-UHFFFAOYSA-N 0.000 abstract 1
- 239000000594 mannitol Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 229960001855 mannitol Drugs 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000000600 sorbitol Substances 0.000 abstract 1
- 235000010356 sorbitol Nutrition 0.000 abstract 1
- 229960002920 sorbitol Drugs 0.000 abstract 1
- 239000000811 xylitol Substances 0.000 abstract 1
- 235000010447 xylitol Nutrition 0.000 abstract 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 abstract 1
- 229960002675 xylitol Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
- A61K9/2826—Sugars or sugar alcohols, e.g. sucrose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se provee una preparacion en donde un ingrediente activo inestable al oxígeno es estabilizada por recubrimiento de una parte que contiene el ingrediente activo inestable al oxígeno con una capa de recubrimiento con azucar que contiene (1) alcohol de azucar como material base de recubrimiento con azucar y (2) un aglutinante. Reivindicacion 2: La preparacion de acuerdo con la reivindicacion 1, caracterizada porque el alcohol de azucar es uno o más de uno seleccionado entre eritritol, manitol, xilitol y sorbitol. Reivindicacion 5: La preparacion de acuerdo con la reivindicacion 1, caracterizada porque el aglutinante es goma arábiga. Reivindicacion 8: La preparacion de acuerdo con la reivindicacion 1, caracterizada porque el ingrediente activo inestable al oxígeno es (R)-5,6-dimetoxi-2-[2,2,46,7-pentametil-3-(4-metilfenil)-2,3-dihidro-1-benzofuran-5-il]isoindolina.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005171443 | 2005-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR054133A1 true AR054133A1 (es) | 2007-06-06 |
Family
ID=37498554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060102421A AR054133A1 (es) | 2005-06-10 | 2006-06-09 | Preparacion recubierta con azucar |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20090030064A1 (es) |
| EP (1) | EP1889611A1 (es) |
| JP (1) | JPWO2006132360A1 (es) |
| KR (1) | KR20080014014A (es) |
| CN (1) | CN101193625A (es) |
| AR (1) | AR054133A1 (es) |
| AU (1) | AU2006256038A1 (es) |
| BR (1) | BRPI0611058A2 (es) |
| CA (1) | CA2610342A1 (es) |
| CR (1) | CR9523A (es) |
| IL (1) | IL187407A0 (es) |
| MA (1) | MA29540B1 (es) |
| NO (1) | NO20080175L (es) |
| NZ (1) | NZ563820A (es) |
| PE (1) | PE20070077A1 (es) |
| RU (1) | RU2407515C2 (es) |
| TW (1) | TW200716207A (es) |
| WO (1) | WO2006132360A1 (es) |
| ZA (1) | ZA200710333B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8673353B2 (en) | 2008-02-11 | 2014-03-18 | Dainippon Sumitomo Pharma Co., Ltd | Tablet having improved elution properties |
| TW201021832A (en) * | 2008-09-30 | 2010-06-16 | Astellas Pharma Inc | Pharmaceutical composition for oral administration |
| SI2474582T1 (en) * | 2009-09-02 | 2018-01-31 | Nippon Soda Co., Ltd. | A coating agent comprising hydroxyalkyl cellulose |
| CN101804042A (zh) * | 2010-04-16 | 2010-08-18 | 山东新华制药股份有限公司 | 普拉格雷片剂的制备方法 |
| US10251194B2 (en) * | 2013-06-17 | 2019-04-02 | Nxp Usa, Inc. | Efficient scheduling in asynchronous contention-based system |
| FR3013186B1 (fr) * | 2013-11-19 | 2019-07-19 | Roquette Freres | Nouveaux snacks non allergenes contenant des proteines vegetales |
| CN103977427A (zh) * | 2014-05-08 | 2014-08-13 | 王�琦 | 一种糖衣产气粉配方及其制备方法 |
| FR3067567B1 (fr) * | 2017-06-19 | 2019-07-05 | Roquette Freres | Nouveau procede de drageification et formes solides drageifiees presentant des formes irregulieres |
| FR3089756B1 (fr) * | 2018-12-17 | 2021-02-19 | Roquette Freres | Formes solides dragéifiées présentant une stabilité améliorée |
| JP7503420B2 (ja) * | 2020-05-18 | 2024-06-20 | 東和薬品株式会社 | フィンゴリモドを含む医薬組成物とその製造方法及び安定化方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0126661B2 (es) * | 1979-10-17 | 1989-05-24 | Roquette Freres | |
| JPH0816052B2 (ja) * | 1988-11-21 | 1996-02-21 | エスエス製薬株式会社 | 糖衣錠 |
| JP3507211B2 (ja) * | 1995-07-13 | 2004-03-15 | 三菱化学株式会社 | 糖衣液及び糖衣錠 |
| CN1297550C (zh) * | 1998-12-04 | 2007-01-31 | 武田药品工业株式会社 | 苯并呋喃衍生物及其制备和用途 |
| JP2001139495A (ja) * | 1999-11-19 | 2001-05-22 | Shin Etsu Chem Co Ltd | フィルムコーティング剤及び経口固形製剤 |
| AT500063A1 (de) * | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
| JP2002047174A (ja) * | 2000-05-26 | 2002-02-12 | Towa Chem Ind Co Ltd | 無糖コーティング製剤及びその製造方法 |
| DE10033023A1 (de) * | 2000-07-07 | 2002-01-31 | Biogrund Gmbh | Filmüberzugszusammensetzung auf Basis von Zellulosederivaten und Zuckeralkoholen |
| JP2002179559A (ja) * | 2000-10-06 | 2002-06-26 | Takeda Chem Ind Ltd | 薄層糖衣錠およびその製造方法 |
| JP4824224B2 (ja) * | 2001-08-28 | 2011-11-30 | 興和株式会社 | 糖衣製剤 |
| JP2003095928A (ja) * | 2001-09-27 | 2003-04-03 | Kowa Co | 糖衣製剤 |
| JP2003113060A (ja) * | 2001-10-02 | 2003-04-18 | Lion Corp | 発泡成分含有糖衣物 |
| JP4336074B2 (ja) * | 2001-11-15 | 2009-09-30 | 三菱商事フードテック株式会社 | 色調および食感が良好な硬質糖衣錠剤 |
| WO2003051355A1 (en) * | 2001-12-19 | 2003-06-26 | Takeda Chemical Industries, Ltd. | Solid compositions containng compounds unstable to oxygen and method for stabilization thereof |
| JP4590034B2 (ja) * | 2002-01-31 | 2010-12-01 | 三菱商事フードテック株式会社 | 硬質糖衣製剤、糖衣液及び硬質糖衣製剤の製造方法 |
| JP2004123578A (ja) * | 2002-09-30 | 2004-04-22 | Dainippon Ink & Chem Inc | 糖衣錠およびその製造方法 |
| JP2005298373A (ja) * | 2004-04-08 | 2005-10-27 | Kyowa Hakko Kogyo Co Ltd | 吸水性アミノ酸含有糖衣錠剤 |
| JP4984455B2 (ja) * | 2004-08-18 | 2012-07-25 | 日本新薬株式会社 | 二重被覆錠剤 |
-
2006
- 2006-06-07 PE PE2006000633A patent/PE20070077A1/es not_active Application Discontinuation
- 2006-06-08 TW TW095120313A patent/TW200716207A/zh unknown
- 2006-06-09 ZA ZA200710333A patent/ZA200710333B/xx unknown
- 2006-06-09 CN CNA2006800206046A patent/CN101193625A/zh active Pending
- 2006-06-09 KR KR1020077028672A patent/KR20080014014A/ko not_active Withdrawn
- 2006-06-09 BR BRPI0611058-4A patent/BRPI0611058A2/pt not_active IP Right Cessation
- 2006-06-09 US US11/921,731 patent/US20090030064A1/en not_active Abandoned
- 2006-06-09 NZ NZ563820A patent/NZ563820A/en not_active IP Right Cessation
- 2006-06-09 AR ARP060102421A patent/AR054133A1/es not_active Application Discontinuation
- 2006-06-09 JP JP2007520182A patent/JPWO2006132360A1/ja not_active Withdrawn
- 2006-06-09 RU RU2007145426/15A patent/RU2407515C2/ru not_active IP Right Cessation
- 2006-06-09 EP EP06766530A patent/EP1889611A1/en not_active Withdrawn
- 2006-06-09 AU AU2006256038A patent/AU2006256038A1/en not_active Abandoned
- 2006-06-09 CA CA002610342A patent/CA2610342A1/en not_active Abandoned
- 2006-06-09 WO PCT/JP2006/311618 patent/WO2006132360A1/ja not_active Ceased
-
2007
- 2007-11-15 IL IL187407A patent/IL187407A0/en unknown
- 2007-11-15 CR CR9523A patent/CR9523A/es not_active Application Discontinuation
- 2007-12-10 MA MA30465A patent/MA29540B1/fr unknown
-
2008
- 2008-01-10 NO NO20080175A patent/NO20080175L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20070077A1 (es) | 2007-02-07 |
| CA2610342A1 (en) | 2006-12-14 |
| KR20080014014A (ko) | 2008-02-13 |
| EP1889611A1 (en) | 2008-02-20 |
| CR9523A (es) | 2008-02-04 |
| BRPI0611058A2 (pt) | 2011-02-22 |
| RU2007145426A (ru) | 2009-06-20 |
| TW200716207A (en) | 2007-05-01 |
| MA29540B1 (fr) | 2008-06-02 |
| US20090030064A1 (en) | 2009-01-29 |
| JPWO2006132360A1 (ja) | 2009-01-08 |
| ZA200710333B (en) | 2009-03-25 |
| WO2006132360A1 (ja) | 2006-12-14 |
| NO20080175L (no) | 2008-03-04 |
| AU2006256038A1 (en) | 2006-12-14 |
| RU2407515C2 (ru) | 2010-12-27 |
| NZ563820A (en) | 2010-03-26 |
| IL187407A0 (en) | 2008-02-09 |
| CN101193625A (zh) | 2008-06-04 |
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