AR044552A1 - Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios - Google Patents

Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios

Info

Publication number: AR044552A1
Authority: AR; Argentina
Prior art keywords: optionally substituted; alkyl; aryl; halogen; heteroaryl
Prior art date: 2003-05-27

Application number

ARP040101792A

Other languages

English (en)

Spanish (es)

Inventor

Roger Bonnert

Rushsana Rasul

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-27

Filing date

2004-05-24

Publication date

2005-09-21

2004-05-24 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2005-09-21 Publication of AR044552A1 publication Critical patent/AR044552A1/es

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ARP040101792A 2003-05-27 2004-05-24 Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios AR044552A1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
SE0301569A SE0301569D0 (sv)	2003-05-27	2003-05-27	Novel compounds
SE0302305A SE0302305D0 (sv)	2003-05-27	2003-08-27	Novel Compounds

Publications (1)

Publication Number	Publication Date
AR044552A1 true AR044552A1 (es)	2005-09-21

Family

ID=33492578

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ARP040101792A AR044552A1 (es)	2003-05-27	2004-05-24	Derivados del indol,composiciones farmaceuticas que los contienen y procesos para su preparacion, de utilidad para el tratamiento de trastornos respiratorios

Country Status (30)

Country	Link
US (4)	US7687535B2 (is)
EP (3)	EP2281815B1 (is)
JP (2)	JP4541361B2 (is)
KR (3)	KR101067586B1 (is)
CN (2)	CN1795174B (is)
AR (1)	AR044552A1 (is)
AT (3)	ATE425965T1 (is)
AU (1)	AU2004242624B2 (is)
BR (1)	BRPI0410711B8 (is)
CA (1)	CA2526866C (is)
CO (1)	CO5630030A2 (is)
CY (3)	CY1109104T1 (is)
DE (2)	DE602004031894D1 (is)
DK (3)	DK2025670T3 (is)
ES (3)	ES2322650T3 (is)
HR (3)	HRP20090281T1 (is)
IL (4)	IL171928A (is)
IS (2)	IS2722B (is)
MX (1)	MXPA05012680A (is)
MY (1)	MY144483A (is)
NO (1)	NO20056130L (is)
NZ (1)	NZ543722A (is)
PL (3)	PL2025670T3 (is)
PT (3)	PT2025670E (is)
RU (1)	RU2361860C2 (is)
SE (2)	SE0301569D0 (is)
SI (3)	SI1656346T1 (is)
TW (2)	TWI328004B (is)
WO (1)	WO2004106302A1 (is)
ZA (1)	ZA200509598B (is)

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GB0913345D0 (en)	2009-07-31	2009-09-16	Astrazeneca Ab	New combination 802
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WO2011073662A1 (en)	2009-12-17	2011-06-23	Astrazeneca Ab	Combination of a benzoxazinone and a further agent for treating respiratory diseases
DK2558447T3 (da)	2010-03-22	2014-11-10	Actelion Pharmaceuticals Ltd	3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazolderivater og deres anvendelse som prostaglandin d2-receptormodulatorer
GB201021992D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	Compound
GB201021979D0 (en)	2010-12-23	2011-02-02	Astrazeneca Ab	New compound
MY165623A (en)	2011-04-14	2018-04-18	Idorsia Pharmaceuticals Ltd	7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
CN104114169A (zh)	2011-12-16	2014-10-22	阿托佩斯治疗有限公司	用于治疗嗜酸细胞性食管炎的crth2拮抗剂和质子泵抑制剂的组合物
CN104602763B (zh)	2012-03-21	2018-08-21	宾夕法尼亚大学理事会	用于调节毛发生长的组合物和方法
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Also Published As

Publication number	Publication date
HK1126773A1 (en)	2009-09-11
WO2004106302A1 (en)	2004-12-09
US20120178764A1 (en)	2012-07-12
CY1112853T1 (el)	2016-02-10
CA2526866A1 (en)	2004-12-09
CN1795174A (zh)	2006-06-28
IL194872A0 (en)	2011-08-01
KR20060015303A (ko)	2006-02-16
CY1109104T1 (el)	2014-07-02
ES2322650T3 (es)	2009-06-24
DE602004031894D1 (de)	2011-04-28
HK1090635A1 (zh)	2006-12-29
PL2025670T3 (pl)	2011-07-29
CO5630030A2 (es)	2006-04-28
JP2010155862A (ja)	2010-07-15
RU2361860C2 (ru)	2009-07-20
ES2382606T3 (es)	2012-06-11
IS2722B (is)	2011-03-15
TWI328004B (en)	2010-08-01
US7687535B2 (en)	2010-03-30
IL212371A0 (en)	2011-06-30
PT2281815E (pt)	2012-05-24
PT2025670E (pt)	2011-05-24
BRPI0410711B1 (pt)	2018-09-25
US20090163518A1 (en)	2009-06-25
EP1656346A1 (en)	2006-05-17
PL2281815T3 (pl)	2012-08-31
ATE425965T1 (de)	2009-04-15
ZA200509598B (en)	2006-12-27
MXPA05012680A (es)	2006-02-08
IS8920A (is)	2010-08-09
CN1795174B (zh)	2011-09-28
BRPI0410711B8 (pt)	2021-05-25
ES2361485T3 (es)	2011-06-17
SI1656346T1 (sl)	2009-08-31
SE0301569D0 (sv)	2003-05-27
HRP20120390T1 (hr)	2012-06-30
PL1656346T3 (pl)	2009-07-31
DK1656346T3 (da)	2009-06-15
HRP20110359T1 (hr)	2011-06-30
DK2281815T3 (da)	2012-06-18
BRPI0410711A (pt)	2006-06-13
AU2004242624B2 (en)	2008-03-13
DK2025670T3 (da)	2011-06-06
EP1656346B1 (en)	2009-03-18
IS8189A (is)	2005-12-20
RU2005137403A (ru)	2006-05-27
SI2025670T1 (sl)	2011-06-30
EP2281815B1 (en)	2012-04-04
CA2526866C (en)	2012-10-16
KR20110051297A (ko)	2011-05-17
AU2004242624A1 (en)	2004-12-09
MY144483A (en)	2011-09-30
SI2281815T1 (sl)	2012-06-29
HK1149563A1 (en)	2011-10-07
TW201024261A (en)	2010-07-01
TW200510301A (en)	2005-03-16
NO20056130L (no)	2006-02-27
EP2281815A1 (en)	2011-02-09
IL171928A0 (en)	2006-04-10
EP2025670A1 (en)	2009-02-18
NZ543722A (en)	2007-05-31
CY1111469T1 (el)	2015-08-05
IL171928A (en)	2011-06-30
KR20110050754A (ko)	2011-05-16
ATE552243T1 (de)	2012-04-15
IL212265A0 (en)	2011-06-30
ATE502010T1 (de)	2011-04-15
CN102391171A (zh)	2012-03-28
JP2007501269A (ja)	2007-01-25
DE602004020072D1 (de)	2009-04-30
SE0302305D0 (sv)	2003-08-27
HRP20090281T1 (hr)	2009-06-30
KR101067586B1 (ko)	2011-09-27
PT1656346E (pt)	2009-05-20
US20110263614A1 (en)	2011-10-27
KR101067535B1 (ko)	2011-09-27
JP4541361B2 (ja)	2010-09-08
EP2025670B1 (en)	2011-03-16
US20080249110A1 (en)	2008-10-09

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