AR033830A1 - Uso de los antagonistas de los receptores de la il-8 en el tratamiento de las infecciones viricas - Google Patents
Uso de los antagonistas de los receptores de la il-8 en el tratamiento de las infecciones viricasInfo
- Publication number
- AR033830A1 AR033830A1 ARP010103395A ARP010103395A AR033830A1 AR 033830 A1 AR033830 A1 AR 033830A1 AR P010103395 A ARP010103395 A AR P010103395A AR P010103395 A ARP010103395 A AR P010103395A AR 033830 A1 AR033830 A1 AR 033830A1
- Authority
- AR
- Argentina
- Prior art keywords
- antagonist
- manufacture
- viric
- antagonists
- infections
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 102000010681 interleukin-8 receptors Human genes 0.000 title abstract 2
- 108010038415 interleukin-8 receptors Proteins 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 206010006458 Bronchitis chronic Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 241000711573 Coronaviridae Species 0.000 abstract 1
- 241000709661 Enterovirus Species 0.000 abstract 1
- 241000430519 Human rhinovirus sp. Species 0.000 abstract 1
- 206010033078 Otitis media Diseases 0.000 abstract 1
- 206010035664 Pneumonia Diseases 0.000 abstract 1
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 208000007451 chronic bronchitis Diseases 0.000 abstract 1
- 201000009240 nasopharyngitis Diseases 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 241000701161 unidentified adenovirus Species 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
- 241000712461 unidentified influenza virus Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Uso de una cantidad efectiva de un antagonista de los receptores de la IL-8 para la manufactura de un medicamento para tratar la sintomatología del resfriado común causado por infección de rinovirus humano, otros enterovirus, herpesvirus, coronavirus, influenzavirus, parainfluenzavirus, virus respiratorio sincitial o adenovirus en un humano que lo necesite. Uso del antagonista mencionado en conjunción con un antihistamínico, un anti inflamatorio. Uso del antagonista en done se administra oralmente o por inhalación. Uso del antagonista para la manufactura de un medicamento para tratar el asma, bronquitis crónica, enfermedad pulmonar obstructiva crónica, otitis media, sinucitis y neumonía.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21905300P | 2000-07-18 | 2000-07-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR033830A1 true AR033830A1 (es) | 2004-01-07 |
Family
ID=22817645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010103395A AR033830A1 (es) | 2000-07-18 | 2001-07-16 | Uso de los antagonistas de los receptores de la il-8 en el tratamiento de las infecciones viricas |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP1307190A4 (es) |
| JP (1) | JP2004509852A (es) |
| KR (1) | KR20030019587A (es) |
| CN (1) | CN1449285A (es) |
| AR (1) | AR033830A1 (es) |
| AU (1) | AU2001273497A1 (es) |
| BR (1) | BR0112603A (es) |
| CA (1) | CA2418162A1 (es) |
| CZ (1) | CZ2003132A3 (es) |
| HU (1) | HUP0300754A3 (es) |
| IL (1) | IL153921A0 (es) |
| MX (1) | MXPA03000500A (es) |
| NO (1) | NO20030201L (es) |
| NZ (1) | NZ523659A (es) |
| PL (1) | PL365886A1 (es) |
| WO (1) | WO2002005814A1 (es) |
| ZA (1) | ZA200300474B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060030550A1 (en) * | 2004-08-04 | 2006-02-09 | Lithgow Theodore L | Pharmaceutical formulations |
| PE20170185A1 (es) * | 2014-05-12 | 2017-04-01 | Glaxosmithkline Intellectual Property (No 2) Ltd | Composiciones farmaceuticas para tratar enfermedades infecciosas |
| BR112022018294A2 (pt) * | 2020-03-26 | 2023-01-10 | Dompe Farm Spa | Inibidores de cxcl8 para uso no tratamento de covid-19 |
| EP4008325A1 (en) * | 2020-12-02 | 2022-06-08 | Dompe' Farmaceutici S.P.A. | Cxcl8 inhibitors for use in the treatment of covid-19 |
| EP3884932A1 (en) * | 2020-03-26 | 2021-09-29 | Dompe' Farmaceutici S.P.A. | Cxcl8 inhibitors for use in the treatment of covid-19 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5547979A (en) * | 1992-03-30 | 1996-08-20 | Smithkline Beecham | TNF inhibition |
| WO1996005836A2 (en) * | 1994-08-25 | 1996-02-29 | Medical University Of South Carolina | Methods of treating cold symptoms using pentoxifylline |
| JPH11503110A (ja) * | 1995-02-17 | 1999-03-23 | スミスクライン・ビーチャム・コーポレイション | Il−8受容体拮抗剤 |
| SE9802729D0 (sv) * | 1998-08-13 | 1998-08-13 | Astra Pharma Prod | Novel Compounds |
| SE9802937D0 (sv) * | 1998-09-01 | 1998-09-01 | Astra Pharma Prod | Novel compounds |
-
2001
- 2001-07-16 NZ NZ523659A patent/NZ523659A/en unknown
- 2001-07-16 EP EP01952777A patent/EP1307190A4/en not_active Withdrawn
- 2001-07-16 AR ARP010103395A patent/AR033830A1/es not_active Application Discontinuation
- 2001-07-16 CZ CZ2003132A patent/CZ2003132A3/cs unknown
- 2001-07-16 CN CN01813095A patent/CN1449285A/zh active Pending
- 2001-07-16 PL PL01365886A patent/PL365886A1/xx not_active Application Discontinuation
- 2001-07-16 CA CA002418162A patent/CA2418162A1/en not_active Abandoned
- 2001-07-16 KR KR10-2003-7000717A patent/KR20030019587A/ko not_active Withdrawn
- 2001-07-16 HU HU0300754A patent/HUP0300754A3/hu unknown
- 2001-07-16 AU AU2001273497A patent/AU2001273497A1/en not_active Abandoned
- 2001-07-16 WO PCT/US2001/022328 patent/WO2002005814A1/en not_active Ceased
- 2001-07-16 BR BR0112603-2A patent/BR0112603A/pt not_active IP Right Cessation
- 2001-07-16 JP JP2002511746A patent/JP2004509852A/ja not_active Withdrawn
- 2001-07-16 MX MXPA03000500A patent/MXPA03000500A/es unknown
- 2001-07-16 IL IL15392101A patent/IL153921A0/xx unknown
-
2003
- 2003-01-15 NO NO20030201A patent/NO20030201L/no not_active Application Discontinuation
- 2003-01-17 ZA ZA200300474A patent/ZA200300474B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1449285A (zh) | 2003-10-15 |
| NO20030201L (no) | 2003-03-17 |
| CA2418162A1 (en) | 2002-01-24 |
| NO20030201D0 (no) | 2003-01-15 |
| HUP0300754A3 (en) | 2009-03-02 |
| JP2004509852A (ja) | 2004-04-02 |
| EP1307190A1 (en) | 2003-05-07 |
| MXPA03000500A (es) | 2003-06-24 |
| ZA200300474B (en) | 2004-08-17 |
| BR0112603A (pt) | 2004-08-24 |
| AU2001273497A1 (en) | 2002-01-30 |
| IL153921A0 (en) | 2003-07-31 |
| EP1307190A4 (en) | 2007-08-22 |
| KR20030019587A (ko) | 2003-03-06 |
| CZ2003132A3 (cs) | 2003-09-17 |
| NZ523659A (en) | 2006-01-27 |
| WO2002005814A1 (en) | 2002-01-24 |
| PL365886A1 (en) | 2005-01-10 |
| HUP0300754A2 (hu) | 2003-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |