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AR038200A1 - Procedimiento y aparato para preparar particulas cristalinas - Google Patents

Procedimiento y aparato para preparar particulas cristalinas

Info

Publication number
AR038200A1
AR038200A1 ARP030100169A ARP030100169A AR038200A1 AR 038200 A1 AR038200 A1 AR 038200A1 AR P030100169 A ARP030100169 A AR P030100169A AR P030100169 A ARP030100169 A AR P030100169A AR 038200 A1 AR038200 A1 AR 038200A1
Authority
AR
Argentina
Prior art keywords
procedure
crystal particles
prepare crystal
substance
solvent
Prior art date
Application number
ARP030100169A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR038200A1 publication Critical patent/AR038200A1/es

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • B01D9/0054—Use of anti-solvent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0059—General arrangements of crystallisation plant, e.g. flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0081—Use of vibrations, e.g. ultrasound
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/20—Jet mixers, i.e. mixers using high-speed fluid streams
    • B01F25/25—Mixing by jets impinging against collision plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/80—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations
    • B01F31/85—Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations with a vibrating element inside the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/712—Feed mechanisms for feeding fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7174—Feed mechanisms characterised by the means for feeding the components to the mixer using pistons, plungers or syringes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7176—Feed mechanisms characterised by the means for feeding the components to the mixer using pumps
    • B01F35/717611—Peristaltic pumps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/71805—Feed mechanisms characterised by the means for feeding the components to the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/75—Discharge mechanisms
    • B01F35/754—Discharge mechanisms characterised by the means for discharging the components from the mixer
    • B01F35/7547—Discharge mechanisms characterised by the means for discharging the components from the mixer using valves, gates, orifices or openings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/18—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using a vibrating apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Steroid Compounds (AREA)

Abstract

Un procedimiento y aparato para preparar partículas cristalinas que comprende mezclar en una celda de flujo continuo en presencia de radiación ultrasónica de una solución de una sustancia en un líquido solvente con un anti-solvente líquido para dicha sustancia.
ARP030100169A 2002-01-22 2003-01-21 Procedimiento y aparato para preparar particulas cristalinas AR038200A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0201400.9A GB0201400D0 (en) 2002-01-22 2002-01-22 Novel apparatus and process

Publications (1)

Publication Number Publication Date
AR038200A1 true AR038200A1 (es) 2005-01-05

Family

ID=9929515

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030100169A AR038200A1 (es) 2002-01-22 2003-01-21 Procedimiento y aparato para preparar particulas cristalinas

Country Status (22)

Country Link
US (1) US7384478B2 (es)
EP (1) EP1469938B1 (es)
JP (1) JP4408700B2 (es)
KR (1) KR20040082395A (es)
CN (1) CN1620333A (es)
AR (1) AR038200A1 (es)
AT (1) ATE312661T1 (es)
BR (1) BR0306738A (es)
CA (1) CA2473059A1 (es)
CO (1) CO5611178A2 (es)
DE (1) DE60302765T2 (es)
ES (1) ES2253656T3 (es)
GB (1) GB0201400D0 (es)
IL (1) IL162751A0 (es)
IS (1) IS7335A (es)
MX (1) MXPA04007073A (es)
NO (1) NO20043444L (es)
PL (1) PL372897A1 (es)
RU (1) RU2004120549A (es)
TW (1) TW200302129A (es)
WO (1) WO2003061816A1 (es)
ZA (1) ZA200405143B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005177746A (ja) * 2003-11-28 2005-07-07 Mitsubishi Chemicals Corp 有機化合物微粒子の製造方法
CN1878602A (zh) * 2003-11-28 2006-12-13 三菱化学株式会社 有机化合物微粒的制造方法
GB0406069D0 (en) * 2004-03-17 2004-04-21 Thompson James Process
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
DE102005053862A1 (de) * 2005-11-04 2007-05-10 Pharmasol Gmbh Verfahren und Vorrichtung zur Herstellung hochfeiner Partikel sowie zur Beschichtung solcher Partikel
JP4597107B2 (ja) * 2006-03-02 2010-12-15 三井金属鉱業株式会社 砒素含有体からの砒素除去方法及び砒素除去装置
BRPI0709872A2 (pt) * 2006-04-03 2011-07-26 Teva Pharma micropartÍculas de drogas
GB0705159D0 (en) 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals
GB0711680D0 (en) 2007-06-18 2007-07-25 Prosonix Ltd Process
GB0900080D0 (en) 2009-01-06 2009-02-11 Prosonix Ltd An apparatus and process for producing crystals
GB0918150D0 (en) * 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
EP2500072A1 (en) * 2011-03-15 2012-09-19 LEK Pharmaceuticals d.d. A novel process of residual solvent removal
KR20140048237A (ko) * 2011-07-08 2014-04-23 화이자 리미티드 플루티카손 프로피오네이트 형태 1의 제조 방법
CN103958744B (zh) * 2011-07-14 2016-08-31 科瓦里斯股份有限公司 用于使用聚焦声制备纳米晶体组合物的系统和方法
JP5848621B2 (ja) * 2012-01-25 2016-01-27 浜松ホトニクス株式会社 薬物評価方法及び薬物評価装置
WO2013169647A1 (en) 2012-05-08 2013-11-14 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
HK1215545A1 (zh) 2013-01-31 2016-09-02 Circassia Limited 适用於吸入治疗的包含多组分结晶颗粒的药物组合物
US9855538B2 (en) 2013-03-08 2018-01-02 The Board Of Trustees Of The University Of Illinois Ultrasonic method and apparatus for producing particles having a controlled size distribution
CN103977593B (zh) * 2014-05-19 2017-01-04 中国工程物理研究院化工材料研究所 制备纳米共晶含能材料的方法及装置
DE102021121631A1 (de) 2021-08-20 2023-02-23 Dionex Softron Gmbh Mischanordnung
WO2026004845A1 (ja) * 2024-06-25 2026-01-02 株式会社カネカ 連続析出による固体物の製造方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4930820B1 (es) * 1966-02-10 1974-08-16
US3749318A (en) * 1971-03-01 1973-07-31 E Cottell Combustion method and apparatus burning an intimate emulsion of fuel and water
JPS5756031A (en) * 1980-09-19 1982-04-03 Toshiba Corp Ultrasonic emulsifier
JPS58163425A (ja) * 1982-03-25 1983-09-28 Toshiba Corp 超音波乳化装置
US5032027A (en) * 1989-10-19 1991-07-16 Heat Systems Incorporated Ultrasonic fluid processing method
HUT59692A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alkanoic acids and aminosugars
JP3178873B2 (ja) * 1991-12-20 2001-06-25 第一高周波工業株式会社 超音波を利用した液体混合方法
US5471001A (en) * 1994-12-15 1995-11-28 E. I. Du Pont De Nemours And Company Crystallization of adipic acid
JP3630834B2 (ja) * 1995-04-24 2005-03-23 株式会社リコー 二種以上の樹脂原料液体の混合法及びその混合装置
DE19712488A1 (de) * 1997-03-25 1998-10-01 Knoell Hans Forschung Ev Steroidsulfamate, Verfahren zu ihrer Herstellung und Anwendung derselben
US20010023252A1 (en) * 1998-07-02 2001-09-20 Smithkline Beecham Plc Novel compound
GB9828721D0 (en) * 1998-12-24 1999-02-17 Glaxo Group Ltd Novel apparatus and process
WO2000044468A1 (en) * 1999-01-29 2000-08-03 Bristol-Myers Squibb Company Sonic impinging jet crystallization apparatus and process

Also Published As

Publication number Publication date
CN1620333A (zh) 2005-05-25
US7384478B2 (en) 2008-06-10
ES2253656T3 (es) 2006-06-01
JP2005525216A (ja) 2005-08-25
RU2004120549A (ru) 2005-05-10
JP4408700B2 (ja) 2010-02-03
NO20043444L (no) 2004-08-18
DE60302765T2 (de) 2006-07-06
MXPA04007073A (es) 2004-10-29
BR0306738A (pt) 2004-12-28
KR20040082395A (ko) 2004-09-24
US20060096522A1 (en) 2006-05-11
EP1469938A1 (en) 2004-10-27
IL162751A0 (en) 2005-11-20
PL372897A1 (en) 2005-08-08
ATE312661T1 (de) 2005-12-15
DE60302765D1 (de) 2006-01-19
EP1469938B1 (en) 2005-12-14
IS7335A (is) 2004-06-28
GB0201400D0 (en) 2002-03-13
CA2473059A1 (en) 2003-07-31
CO5611178A2 (es) 2006-02-28
TW200302129A (en) 2003-08-01
WO2003061816A1 (en) 2003-07-31
ZA200405143B (en) 2005-12-28

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