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AR036915A1 - Produccion de heparina a partir de cultivos de mastocitos - Google Patents

Produccion de heparina a partir de cultivos de mastocitos

Info

Publication number
AR036915A1
AR036915A1 ARP020103974A ARP020103974A AR036915A1 AR 036915 A1 AR036915 A1 AR 036915A1 AR P020103974 A ARP020103974 A AR P020103974A AR P020103974 A ARP020103974 A AR P020103974A AR 036915 A1 AR036915 A1 AR 036915A1
Authority
AR
Argentina
Prior art keywords
production
cultures
mastocy
heparine
heparin
Prior art date
Application number
ARP020103974A
Other languages
English (en)
Inventor
Jean Marc Guillaume
Pierre Cans
Helene Monique Marie Rigal
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR036915A1 publication Critical patent/AR036915A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente es atinente a la producción de heparina a partir de cultivos celulares de mastocitos y, en especial, de mastocitos de cerdo. Reivindicación 1: Procedimiento para la producción de heparina, que se caracteriza por comprender el cultivo de líneas de mastocitos de origen porcino y la recuperación de la heparina a partir de los cultivos obtenidos.
ARP020103974A 2001-10-22 2002-10-21 Produccion de heparina a partir de cultivos de mastocitos AR036915A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0113606A FR2831186B1 (fr) 2001-10-22 2001-10-22 Production d'heparine a partir de cultures de mastocytes

Publications (1)

Publication Number Publication Date
AR036915A1 true AR036915A1 (es) 2004-10-13

Family

ID=8868558

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020103974A AR036915A1 (es) 2001-10-22 2002-10-21 Produccion de heparina a partir de cultivos de mastocitos

Country Status (18)

Country Link
US (1) US20050042733A1 (es)
EP (1) EP1438415A2 (es)
JP (1) JP2005506092A (es)
KR (1) KR20040071127A (es)
CN (1) CN1575341A (es)
AR (1) AR036915A1 (es)
BR (1) BR0213478A (es)
CA (1) CA2462714A1 (es)
CO (1) CO5570711A2 (es)
FR (1) FR2831186B1 (es)
HU (1) HUP0401794A2 (es)
IL (1) IL161066A0 (es)
MX (1) MXPA04003740A (es)
NO (1) NO20041633L (es)
NZ (1) NZ532414A (es)
PL (1) PL368599A1 (es)
WO (1) WO2003035886A2 (es)
ZA (1) ZA200402304B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2853663B1 (fr) * 2003-04-14 2007-08-31 Aventis Pharma Sa Procede d'obtention de lignees de mastocytes a partir de tissus de porcs et procede de production de molecules de type heparine
FR2876386B1 (fr) * 2004-10-12 2007-04-06 Aventis Pharma Sa Lignees de mastocytes porcins produisant des molecules de type heparine
KR100688553B1 (ko) * 2005-06-22 2007-03-02 삼성전자주식회사 코어 사이즈를 감소시킨 반도체 메모리 장치
KR101447123B1 (ko) * 2014-02-27 2014-10-06 박상협 헤파린의 추출 방법
KR102104367B1 (ko) 2019-09-02 2020-04-24 팜앤바이오 주식회사 헤파린나트륨의 제조장치 및 제조방법
CN111979193A (zh) * 2019-09-27 2020-11-24 云南洛宇生物科技有限公司 大鼠骨髓源肥大细胞培养方法
CN110592165B (zh) * 2019-10-18 2021-04-27 福州大学 燕窝中硫酸乙酰肝素/肝素的提取方法与结构解析

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3016331A (en) * 1960-01-28 1962-01-09 Ormonoterapia Richter Spa Purification of heparin
AU5810690A (en) * 1989-05-19 1990-12-18 University Of Alabama, The Heparin-producing murine mastocytoma cell lines
DK0733207T3 (da) * 1993-12-10 1998-04-20 Genentech Inc Fremgangsmåder til diagnose af allergi og screening af anti-allergi-terapeutika
FI974321A0 (fi) * 1997-11-25 1997-11-25 Jenny Ja Antti Wihurin Rahasto Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa
US6596705B1 (en) * 1998-02-09 2003-07-22 The Regents Of The University Of California Inhibition of L-selectin and P-selection mediated binding using heparin

Also Published As

Publication number Publication date
PL368599A1 (en) 2005-04-04
ZA200402304B (en) 2004-10-07
BR0213478A (pt) 2004-11-03
KR20040071127A (ko) 2004-08-11
US20050042733A1 (en) 2005-02-24
IL161066A0 (en) 2004-08-31
MXPA04003740A (es) 2005-06-20
HUP0401794A2 (hu) 2004-11-29
NZ532414A (en) 2006-12-22
JP2005506092A (ja) 2005-03-03
CO5570711A2 (es) 2005-10-31
WO2003035886A2 (fr) 2003-05-01
EP1438415A2 (fr) 2004-07-21
NO20041633L (no) 2004-04-21
CA2462714A1 (fr) 2003-05-01
CN1575341A (zh) 2005-02-02
FR2831186A1 (fr) 2003-04-25
WO2003035886A3 (fr) 2004-02-26
FR2831186B1 (fr) 2004-06-18

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal