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BR0307330A - Produção do delta-9-tetraidrocanabinol - Google Patents

Produção do delta-9-tetraidrocanabinol

Info

Publication number
BR0307330A
BR0307330A BR0307330-0A BR0307330A BR0307330A BR 0307330 A BR0307330 A BR 0307330A BR 0307330 A BR0307330 A BR 0307330A BR 0307330 A BR0307330 A BR 0307330A
Authority
BR
Brazil
Prior art keywords
delta
acid
production
thc
tetrahydrocannabinol
Prior art date
Application number
BR0307330-0A
Other languages
English (en)
Inventor
Neil John Goodwin
Nicolas James Archer
Christopher Murray
Alan Kenneth Greenwood
Derek Mchattie
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0202396A external-priority patent/GB0202396D0/en
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Publication of BR0307330A publication Critical patent/BR0307330A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Optical Integrated Circuits (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Steroid Compounds (AREA)

Abstract

"PRODUçãO DO DELTA-9-TETRAIDROCANABINOL". O ácido delta 9-THC é obtido a partir de um material vegetal e extraído por um solvente aquoso sob condições de pH controlado. O ácido é convertido em um sal e o sal extraído em um solvente polar, produzindo ácido de alta pureza. o ácido delta 9-THC é então convertido a delta 9-THC que é posteriormente purificado e combinado com um carreador para uso farmacêutico.
BR0307330-0A 2002-02-01 2003-02-03 Produção do delta-9-tetraidrocanabinol BR0307330A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0202396A GB0202396D0 (en) 2002-02-01 2002-02-01 Production of delta 9 tetrahydrocannabinol
GB0214022A GB0214022D0 (en) 2002-02-01 2002-06-18 Production of delta 9 tetrahydrocannabinol
PCT/GB2003/000441 WO2003064407A2 (en) 2002-02-01 2003-02-03 Production of δ9 tetrahydrocannabinol

Publications (1)

Publication Number Publication Date
BR0307330A true BR0307330A (pt) 2004-12-07

Family

ID=27665366

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307330-0A BR0307330A (pt) 2002-02-01 2003-02-03 Produção do delta-9-tetraidrocanabinol

Country Status (17)

Country Link
US (3) US7524881B2 (pt)
EP (2) EP1474412B1 (pt)
JP (1) JP2005526715A (pt)
CN (2) CN1642934A (pt)
AT (1) ATE396984T1 (pt)
AU (2) AU2003205844B2 (pt)
BR (1) BR0307330A (pt)
CA (1) CA2474951A1 (pt)
DE (2) DE60332776D1 (pt)
DK (1) DK1474412T3 (pt)
ES (1) ES2305437T3 (pt)
NO (1) NO20043209L (pt)
NZ (2) NZ552547A (pt)
PT (1) PT1474412E (pt)
SI (1) SI1474412T1 (pt)
WO (1) WO2003064407A2 (pt)
ZA (1) ZA200405938B (pt)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE396984T1 (de) * 2002-02-01 2008-06-15 Resolution Chemicals Ltd Gewinnung von delta-9 tetrahydrocannabinol
GB2391865B (en) * 2002-08-14 2005-06-01 Gw Pharma Ltd Improvements in the extraction of pharmaceutically active components from plant materials
PL226646B1 (pl) * 2002-08-14 2017-08-31 Gw Pharma Ltd Botaniczna substancja lekowa
GB0222077D0 (en) 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material
GB2408978B (en) * 2002-09-23 2006-04-05 Gw Pharma Ltd Methods of preparing delta-9 tetrahydrocannabinol from plant material
TWI369203B (en) * 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
KR20070118069A (ko) * 2004-12-09 2007-12-13 인시스 테라퓨틱스, 인코포레이티드 실온에서 안정한 드로나비놀 제형
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
CA2623723A1 (en) 2005-09-29 2007-04-12 Amr Technology, Inc. Process for production of delta-9-tetrahydrocannabinol
CA2659775A1 (en) * 2006-08-04 2008-02-14 Insys Therapeutics Inc. Aqueous dronabinol formulations
US20080103193A1 (en) * 2006-10-26 2008-05-01 Trevor Percival Castor Methods for making compositions and compositions for treating pain and cachexia
GB0703284D0 (en) 2007-02-20 2007-03-28 Resolution Chemicals Ltd Delta 9 - tetrahydrocannabinol processing
CA2698752A1 (en) * 2007-08-06 2009-02-12 Insys Therapeutics Inc. Oral cannabinoid liquid formulations and methods of treatment
US20090042974A1 (en) * 2007-08-07 2009-02-12 Anson David Parker Compositions And Methods Relating To Extensible Transgenic Vector Assembler, Pestilence Ridder, Plus Cannabinoid Producer
GB0807915D0 (en) * 2008-05-01 2008-06-04 Resolution Chemicals Ltd Production of delta 9 tetrahydrocannabinol
US8343553B2 (en) 2011-04-18 2013-01-01 Hospodor Andrew D Essential element extractor
EP2760444B1 (de) * 2011-09-29 2020-04-22 THC Pharm GmbH The Health Concept Cannabinoidcarbonsäuren, salze von cannabinoidcarbonsäuren, deren herstellung und anwendungen
US9358259B2 (en) 2012-03-20 2016-06-07 Andrew David Hospodor Recycling cannabinoid extractor
JP2015515977A (ja) * 2012-05-03 2015-06-04 エコ・ファーマシューティカルズ・ビー．ブイ．Ｅｃｈｏ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｂ．Ｖ． Δ９−テトラヒドロカンナビノールを含む大麻草単離物及びこのような単離物を製造するための方法
US20130337052A1 (en) * 2012-06-19 2013-12-19 Patricia Linert System and Method of Reducing Impairment of Alertness, Concentration, Motivation, and Creativity Caused by Medication
US9155767B2 (en) 2012-10-18 2015-10-13 Andrew D. Hospodor Essential element management
EP4137142A1 (en) * 2013-03-14 2023-02-22 Purple Mundo, Inc. Bioactive concentrates and uses thereof
US9199960B2 (en) * 2013-05-02 2015-12-01 Frederick R. Ferri Method and apparatus for processing herbaceous plant materials including the cannabis plant
US9380813B2 (en) 2014-02-11 2016-07-05 Timothy McCullough Drug delivery system and method
US9220294B2 (en) 2014-02-11 2015-12-29 Timothy McCullough Methods and devices using cannabis vapors
US10821240B2 (en) 2014-02-11 2020-11-03 Vapor Cartridge Technology Llc Methods and drug delivery devices using cannabis
US20170312327A1 (en) * 2014-11-17 2017-11-02 Connoisseur Holdings, Llc Extraction devices, systems, and methods
US10207198B2 (en) * 2015-01-22 2019-02-19 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
US11034639B2 (en) 2015-01-22 2021-06-15 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
BR112017015536B1 (pt) * 2015-01-22 2021-05-18 Phytoplant Research S.L métodos de purificação de canabinoides
US11040295B2 (en) 2015-02-06 2021-06-22 Joseph Francis Payack Method and apparatus for extracting plant oils using ethanol water
US10059684B2 (en) 2015-05-07 2018-08-28 Axim Biotechnologies, Inc. Process to extract and purify Δ9-tetrahydrocannabinol
US10913071B2 (en) 2016-03-09 2021-02-09 Pearson Incorporated Scalper apparatus and processing system
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
EP3478307A4 (en) 2016-06-29 2020-02-26 Cannscience Innovations Inc. DECARBOXYLATED CANNABIS RESINS, USES THEREOF AND METHOD FOR THE PRODUCTION THEREOF
MX381066B (es) * 2016-07-15 2025-03-12 Steiner Inc S S Descarboxilación de ácido cannabidiólico en biomasa de cañamo y extracto de cañamo.
US10322487B1 (en) 2016-07-15 2019-06-18 Pearson Incorporated Roller mill grinding apparatus with regenerative capability
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US10702495B2 (en) 2017-02-20 2020-07-07 Nexien Biopharma, Inc. Method and compositions for treating dystrophies and myotonia
US10807098B1 (en) 2017-07-26 2020-10-20 Pearson Incorporated Systems and methods for step grinding
IT201700085508A1 (it) * 2017-07-26 2019-01-26 Inalco S R L Metodo per la produzione di cannabinoidi da varietà di canapa industriale
US10272360B2 (en) 2017-08-05 2019-04-30 Priya Naturals, Inc. Phytochemical extraction system and methods to extract phytochemicals from plants including plants of the family Cannabaceae sensu stricto
US10406453B2 (en) * 2017-09-29 2019-09-10 NextLeaf Solutions Ltd. Cannabinoid extraction process using brine
US10941102B2 (en) * 2017-11-29 2021-03-09 Robert Henry Wohleb Aqueous leaching method to produce microcrystalline powder
CN111788171A (zh) * 2018-01-29 2020-10-16 菲拓普兰特研究公司 使用液：液色谱法纯化大麻素的方法
US11202771B2 (en) 2018-01-31 2021-12-21 Treehouse Biotech, Inc. Hemp powder
US11325133B1 (en) 2018-07-26 2022-05-10 Pearson Incorporated Systems and methods for monitoring the roll diameter and shock loads in a milling apparatus
WO2020060959A1 (en) * 2018-09-17 2020-03-26 Sorbent Technologies, Inc. Methods for removing contaminants from plant-derived pharmaceuticals
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
US10751722B1 (en) 2018-10-24 2020-08-25 Pearson Incorporated System for processing cannabis crop materials
US20220079880A1 (en) * 2019-01-17 2022-03-17 Thomas Piccariello Solid micellar compositions of cannabinoid acids
US10785906B2 (en) 2019-02-19 2020-09-29 Pearson Incorporated Plant processing system
WO2020194297A1 (en) * 2019-03-24 2020-10-01 Omega Life Science Ltd. Electronic cigarettes
WO2020210119A1 (en) 2019-04-11 2020-10-15 Mantrose-Haeuser Co., Inc. Cannabis delivery with protective glaze coating
CA3137735A1 (en) 2019-04-23 2020-10-29 Soma Oil Llc Cannabis processing systems and methods
EP3750528A1 (en) 2019-06-11 2020-12-16 Nexien Biopharma, Inc. Compositions for treating dystrophies and myotonia
WO2021055079A1 (en) 2019-09-16 2021-03-25 Vapor Cartridge Technology Llc Drug delivery system with stackable substrates
US10757860B1 (en) 2019-10-31 2020-09-01 Hemp Processing Solutions, LLC Stripper apparatus crop harvesting system
US10933424B1 (en) 2019-12-11 2021-03-02 Pearson Incorporated Grinding roll improvements
CN111039760A (zh) * 2019-12-16 2020-04-21 福建省中科生物股份有限公司 一种制备酚类化合物的方法
US11351476B2 (en) * 2020-01-07 2022-06-07 Agrify Corporation Method for chemical separation of cannabinoids
MX2022010960A (es) 2020-03-04 2022-11-16 Pleopharma L L C Métodos y composiciones para tratar el trastorno por uso de cannabis y mitigar la abstinencia de cannabinoides.
US20230271930A1 (en) 2020-06-09 2023-08-31 Protonify Corporation Process for isolation and purification of thca from cannabis
US20230270806A1 (en) 2020-09-04 2023-08-31 Herbolea Biotech S.P.A. Thc-free cannabinoid concentrate, method of obtaining the same and use thereof
US12029718B2 (en) 2021-11-09 2024-07-09 Cct Sciences, Llc Process for production of essentially pure delta-9-tetrahydrocannabinol
US11242328B1 (en) * 2021-02-25 2022-02-08 Acid Neutral Alkaline Laboratory Heterogeneous catalyst and method for preparation of aromatic tricyclic pyrans
US11352337B1 (en) * 2021-06-02 2022-06-07 Acid Neutral Alkaline Laboratory Zeolite catalyst and method for preparation of aromatic tricyclic pyrans
CN115260005B (zh) * 2022-08-30 2024-01-30 晨光生物科技集团股份有限公司 一种纯化提取大麻二酚的方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342971A (en) * 1992-12-29 1994-08-30 The Australian National University Process for the preparation of dibenzo[b,d]pyrans
CA2220223C (en) * 1995-05-05 2008-07-29 Hauser Inc. High purity carnosic acid from rosemary and sage extracts by ph-controlled precipitation
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
US20020039795A1 (en) * 1998-10-26 2002-04-04 Elsohly Et Al Method of preparing delta-9-tetrahydrocannabinol
US6730519B2 (en) * 1998-10-26 2004-05-04 The University Of Mississippi Method of preparing delta-9-tetrahydrocannabinol
ATE396984T1 (de) * 2002-02-01 2008-06-15 Resolution Chemicals Ltd Gewinnung von delta-9 tetrahydrocannabinol

Also Published As

Publication number Publication date
WO2003064407A2 (en) 2003-08-07
US20050049298A1 (en) 2005-03-03
WO2003064407A3 (en) 2003-10-16
PT1474412E (pt) 2008-07-04
ES2305437T3 (es) 2008-11-01
DE60332776D1 (de) 2010-07-08
AU2006252300A1 (en) 2007-01-25
US20050171361A1 (en) 2005-08-04
EP1803717A3 (en) 2007-07-11
JP2005526715A (ja) 2005-09-08
EP1803717B1 (en) 2010-05-26
EP1474412B1 (en) 2008-05-28
AU2003205844B2 (en) 2006-10-12
CN1642934A (zh) 2005-07-20
US7524881B2 (en) 2009-04-28
US20090253783A1 (en) 2009-10-08
NO20043209L (no) 2004-10-28
NZ552547A (en) 2008-03-28
NZ534430A (en) 2007-09-28
AU2006252300B2 (en) 2009-02-12
DK1474412T3 (da) 2008-09-01
EP1474412A2 (en) 2004-11-10
ATE396984T1 (de) 2008-06-15
ZA200405938B (pt) 2006-05-31
CA2474951A1 (en) 2003-08-07
DE60321318D1 (de) 2008-07-10
US7592468B2 (en) 2009-09-22
EP1803717A2 (en) 2007-07-04
CN100999513A (zh) 2007-07-18
SI1474412T1 (sl) 2008-10-31

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