AR036727A1 - Composiciones farmaceuticas para el tratamiento de la fibrosis hepatica y de la infeccion causada por el virus de la hepatitis c y uso de dicha composicion para la manufactura de un medicamento - Google Patents
Composiciones farmaceuticas para el tratamiento de la fibrosis hepatica y de la infeccion causada por el virus de la hepatitis c y uso de dicha composicion para la manufactura de un medicamentoInfo
- Publication number
- AR036727A1 AR036727A1 ARP020103739A ARP020103739A AR036727A1 AR 036727 A1 AR036727 A1 AR 036727A1 AR P020103739 A ARP020103739 A AR P020103739A AR P020103739 A ARP020103739 A AR P020103739A AR 036727 A1 AR036727 A1 AR 036727A1
- Authority
- AR
- Argentina
- Prior art keywords
- hepatitis
- manufacture
- composition
- pharmaceutical compositions
- reduce
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010019668 Hepatic fibrosis Diseases 0.000 title 1
- 206010056522 Hepatic infection Diseases 0.000 title 1
- 241000700605 Viruses Species 0.000 title 1
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- 241000711549 Hepacivirus C Species 0.000 abstract 1
- 102100037850 Interferon gamma Human genes 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 230000007882 cirrhosis Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 230000003908 liver function Effects 0.000 abstract 1
- OHDXDNUPVVYWOV-UHFFFAOYSA-N n-methyl-1-(2-naphthalen-1-ylsulfanylphenyl)methanamine Chemical compound CNCC1=CC=CC=C1SC1=CC=CC2=CC=CC=C12 OHDXDNUPVVYWOV-UHFFFAOYSA-N 0.000 abstract 1
- 230000002459 sustained effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/212—IFN-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Power Sources (AREA)
Abstract
Composiciones farmacéuticas que comprenden una cantidad terapéuticamente efectiva de IFN-alfa e IFN-gama concurrentemente destinadas para reducir la fibrosis hepática; métodos para aumentar la función hepática en un individuo que sufre de fibrosis hepática; métodos para reducir la incidencia de complicaciones asociadas con VHC y cirrosis del hígado; para reducir la carga viral, y métodos para tratar una infección de VHC y uso de dicha composición para la manufactura de una medicamento para reducir la fibrosis hepática o para lograr una respuesta viral sostenida destinada para tratar una infección causada por el virus de la hepatitis C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32774301P | 2001-10-05 | 2001-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR036727A1 true AR036727A1 (es) | 2004-09-29 |
Family
ID=23277847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020103739A AR036727A1 (es) | 2001-10-05 | 2002-10-03 | Composiciones farmaceuticas para el tratamiento de la fibrosis hepatica y de la infeccion causada por el virus de la hepatitis c y uso de dicha composicion para la manufactura de un medicamento |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20050013801A1 (es) |
| EP (1) | EP1450848A4 (es) |
| JP (1) | JP2005508935A (es) |
| KR (1) | KR20050033518A (es) |
| CN (1) | CN1564693A (es) |
| AR (1) | AR036727A1 (es) |
| BR (1) | BR0213093A (es) |
| CA (1) | CA2460341A1 (es) |
| HU (1) | HUP0600449A2 (es) |
| IL (1) | IL161022A0 (es) |
| MX (1) | MXPA04003239A (es) |
| NO (1) | NO20041815L (es) |
| PL (1) | PL371683A1 (es) |
| WO (1) | WO2003030613A2 (es) |
| ZA (1) | ZA200402353B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| WO2006033453A1 (ja) * | 2004-09-22 | 2006-03-30 | Juntendo Educational Foundation | インターフェロン作用物質の活性増強剤 |
| KR20090037347A (ko) * | 2007-10-10 | 2009-04-15 | 한올제약주식회사 | HMG-CoA 환원효소억제제와 담즙산을 포함하는 C형 간염 치료용 약학조성물 |
| JP6632802B2 (ja) * | 2012-01-16 | 2020-01-22 | マッケンナ,エリザベス | 肝疾患及び肝障害を治療するための組成物及び方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096705A (en) * | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
| US6936694B1 (en) * | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| US4462986A (en) * | 1982-11-04 | 1984-07-31 | Ens Bio Logicals, Inc. | Synergistic anti-herpes compositions |
| US5910304A (en) * | 1982-12-13 | 1999-06-08 | Texas A&M University System | Low-dose oral administration of interferons |
| IL76591A0 (en) * | 1984-10-05 | 1986-02-28 | Bioferon Biochem Substanz | Pharmaceutical compositions containing ifn-ypsilon and processes for the preparation thereof |
| US4806347A (en) * | 1985-12-11 | 1989-02-21 | Schering Corporation | Interferon combinations |
| US5082659A (en) * | 1986-10-06 | 1992-01-21 | Board Of Regents, The University Of Texas System | Methods and compositions employing interferon-gamma |
| ZA878295B (en) * | 1986-11-06 | 1988-05-03 | Amarillo Cell Culture Co. Inc. | Treatment of immuno-resistant disease |
| CA1320905C (en) * | 1986-11-06 | 1993-08-03 | Joseph M. Cummins | Treatment of immuno-resistant disease |
| US5190751A (en) * | 1987-01-20 | 1993-03-02 | Schering Corporation | Treatment of certain leukemias with a combination of gamma interferon and alpha interferon |
| WO1988009673A1 (en) * | 1987-06-02 | 1988-12-15 | Schering Corporation | Treatment of chronic type b hepatitis with a combination of recombinant human alpha and gamma interferons |
| US5215744A (en) * | 1987-06-16 | 1993-06-01 | Boehringer Ingelheim Gmbh | Methods for the treatment of tumors |
| ATE174514T1 (de) * | 1989-01-23 | 1999-01-15 | Chiron Corp | Rekombinante zellen für therapien von infektionen und hyperprolieferative störungen und deren herstellung |
| US5141735A (en) * | 1990-06-18 | 1992-08-25 | Hoffman-La Roche, Inc. | Substituted amino-benzodiazepines having anitviral activity |
| TW224053B (es) * | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
| JPH07503851A (ja) * | 1992-02-10 | 1995-04-27 | インターフェロン・サイエンシズ、インコーポレイテッド | 改良インターフェロン及びヒトの末梢血液白血球からのその製造方法 |
| US6077519A (en) * | 1993-01-29 | 2000-06-20 | University Of Pittsburgh | Methods for isolation and use of T cell epitopes eluted from viable cells in vaccines for treating cancer patients |
| US5888511A (en) * | 1993-02-26 | 1999-03-30 | Advanced Biotherapy Concepts, Inc. | Treatment of autoimmune diseases, including AIDS |
| US6200952B1 (en) * | 1993-06-02 | 2001-03-13 | Sciclone Pharmaceuticals, Inc. | Combination therapy method for treating chronic hepatitis B |
| US5830448A (en) * | 1994-06-16 | 1998-11-03 | Genentech, Inc. | Compositions and methods for the treatment of tumors |
| US5565558A (en) * | 1994-12-30 | 1996-10-15 | Mccully; Kilmer S. | Thioretinaco ozonide and enhanced biological activity of thioretinaco ozonide in combination with interferon |
| US5980884A (en) * | 1996-02-05 | 1999-11-09 | Amgen, Inc. | Methods for retreatment of patients afflicted with Hepatitis C using consensus interferon |
| EP1023901A4 (en) * | 1997-10-13 | 2004-10-27 | Otsuka Pharma Co Ltd | MEDICINES FOR HEPATITIS C AND THE USE THEREOF |
| KR20020020809A (ko) * | 1999-08-13 | 2002-03-15 | 프리돌린 클라우스너, 롤란드 비. 보레르 | 페길화-인터페론-알파와 관련된 미코페놀레이트 모페틸 |
-
2002
- 2002-10-03 WO PCT/US2002/030838 patent/WO2003030613A2/en not_active Ceased
- 2002-10-03 EP EP02763767A patent/EP1450848A4/en not_active Withdrawn
- 2002-10-03 HU HU0600449A patent/HUP0600449A2/hu unknown
- 2002-10-03 CN CNA028194888A patent/CN1564693A/zh active Pending
- 2002-10-03 BR BR0213093-9A patent/BR0213093A/pt not_active IP Right Cessation
- 2002-10-03 CA CA002460341A patent/CA2460341A1/en not_active Abandoned
- 2002-10-03 US US10/490,457 patent/US20050013801A1/en not_active Abandoned
- 2002-10-03 MX MXPA04003239A patent/MXPA04003239A/es unknown
- 2002-10-03 PL PL02371683A patent/PL371683A1/xx not_active Application Discontinuation
- 2002-10-03 KR KR1020047005035A patent/KR20050033518A/ko not_active Withdrawn
- 2002-10-03 AR ARP020103739A patent/AR036727A1/es not_active Application Discontinuation
- 2002-10-03 IL IL16102202A patent/IL161022A0/xx unknown
- 2002-10-03 JP JP2003533662A patent/JP2005508935A/ja active Pending
-
2004
- 2004-03-25 ZA ZA200402353A patent/ZA200402353B/xx unknown
- 2004-05-04 NO NO20041815A patent/NO20041815L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04003239A (es) | 2004-07-08 |
| NO20041815L (no) | 2004-06-11 |
| PL371683A1 (en) | 2005-06-27 |
| EP1450848A4 (en) | 2005-11-09 |
| CA2460341A1 (en) | 2003-04-17 |
| ZA200402353B (en) | 2006-03-29 |
| KR20050033518A (ko) | 2005-04-12 |
| WO2003030613A2 (en) | 2003-04-17 |
| BR0213093A (pt) | 2005-03-15 |
| HUP0600449A2 (en) | 2006-09-28 |
| CN1564693A (zh) | 2005-01-12 |
| US20050013801A1 (en) | 2005-01-20 |
| IL161022A0 (en) | 2004-08-31 |
| EP1450848A2 (en) | 2004-09-01 |
| WO2003030613A3 (en) | 2003-11-06 |
| JP2005508935A (ja) | 2005-04-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |