AR035411A1 - Uso de un derivado de tacrolimus para fabricar un agente neurotrofico, composiciones y articulos de fabricacion o kits que lo comprenden, metodo para fabricar un agente que lo comprende y tejidos e injertos con una celula nerviosa tratada con este compuesto - Google Patents
Uso de un derivado de tacrolimus para fabricar un agente neurotrofico, composiciones y articulos de fabricacion o kits que lo comprenden, metodo para fabricar un agente que lo comprende y tejidos e injertos con una celula nerviosa tratada con este compuestoInfo
- Publication number
- AR035411A1 AR035411A1 ARP010106058A ARP010106058A AR035411A1 AR 035411 A1 AR035411 A1 AR 035411A1 AR P010106058 A ARP010106058 A AR P010106058A AR P010106058 A ARP010106058 A AR P010106058A AR 035411 A1 AR035411 A1 AR 035411A1
- Authority
- AR
- Argentina
- Prior art keywords
- agent
- manufacturing
- manufacture
- derivative
- graints
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000508 neurotrophic effect Effects 0.000 title abstract 4
- QJJXYPPXXYFBGM-LFZNUXCKSA-N Tacrolimus Chemical class C1C[C@@H](O)[C@H](OC)C[C@@H]1\C=C(/C)[C@@H]1[C@H](C)[C@@H](O)CC(=O)[C@H](CC=C)/C=C(C)/C[C@H](C)C[C@H](OC)[C@H]([C@H](C[C@H]2C)OC)O[C@@]2(O)C(=O)C(=O)N2CCCC[C@H]2C(=O)O1 QJJXYPPXXYFBGM-LFZNUXCKSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 title 1
- 239000004744 fabric Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 210000002569 neuron Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000005709 nerve cell growth Effects 0.000 abstract 1
- 239000005022 packaging material Substances 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Packages (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
El uso de un derivado de tacrolimus de fórmula (1) para la fabricación de un agente neurotrófico. El derivado de fórmula (1) posee un nivel alto de actividad neurotrófica y un nivel reducido de actividad inmunosupresora. Composición que comprende al derivado de fórmula (1) y un artículo de fabricación o un kit que comprende un material de envasado dentro del que se incluye el compuesto (1). Métodos para realizar o fabricar un agente neurotrófico que comprende al compuesto (1). Composición que comprende una célula nerviosa tratada con el compuesto (1). Tejido o injerto que comprenden una célula nerviosa tratada con el compuesto de fórmula (1). Composición que comprende una célula, tejido o injerto tratados con el compuesto (1) y al menos un agente promotor del crecimiento de la célula nerviosa.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25850000P | 2000-12-29 | 2000-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR035411A1 true AR035411A1 (es) | 2004-05-26 |
Family
ID=22980816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010106058A AR035411A1 (es) | 2000-12-29 | 2001-12-27 | Uso de un derivado de tacrolimus para fabricar un agente neurotrofico, composiciones y articulos de fabricacion o kits que lo comprenden, metodo para fabricar un agente que lo comprende y tejidos e injertos con una celula nerviosa tratada con este compuesto |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1353671A4 (es) |
| JP (1) | JP2004527472A (es) |
| KR (2) | KR20070030331A (es) |
| CN (1) | CN1293877C (es) |
| AR (1) | AR035411A1 (es) |
| AU (1) | AU2002231277B2 (es) |
| BR (1) | BR0116762A (es) |
| CA (1) | CA2433384A1 (es) |
| CZ (1) | CZ20032060A3 (es) |
| HU (1) | HUP0302521A3 (es) |
| IL (1) | IL156664A0 (es) |
| MX (1) | MXPA03005941A (es) |
| NO (1) | NO20032913D0 (es) |
| NZ (1) | NZ527209A (es) |
| PL (1) | PL366301A1 (es) |
| RU (1) | RU2288716C2 (es) |
| WO (1) | WO2002053159A1 (es) |
| ZA (1) | ZA200305806B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003901023A0 (en) * | 2003-03-04 | 2003-03-20 | Fujisawa Pharmaceutical Co., Ltd. | New use |
| EP1706117A1 (en) * | 2004-01-20 | 2006-10-04 | Astellas Pharma Inc. | Method for treating erectile dysfunction |
| EP1810675A1 (en) * | 2006-01-18 | 2007-07-25 | Institut Curie | Method for treating Huntington's disease by inhibiting dephosphorylation of huntingtin at S421 |
| JP2009102226A (ja) * | 2006-02-14 | 2009-05-14 | Meiji Milk Prod Co Ltd | 脊髄損傷治療剤 |
| BRPI0916232A2 (pt) * | 2008-07-23 | 2017-08-29 | Novartis Ag | Moduladores do receptor de esfingosina-1-fosfato e seu uso para tratar inflamação muscular |
| EP2817009A1 (en) * | 2012-02-23 | 2014-12-31 | INSERM - Institut National de la Santé et de la Recherche Médicale | Calcineurin inhibitors for use in the treatment of lesional vestibular disorders |
| GB201309375D0 (en) * | 2013-05-24 | 2013-07-10 | Chronos Therapeutics Ltd | Medical methods and compounds for medical use |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US537663A (en) * | 1895-04-16 | wubstee | ||
| ES2071681T3 (es) * | 1987-12-09 | 1995-07-01 | Fisons Plc | Compuestos macrociclicos. |
| GR1001225B (el) * | 1989-09-14 | 1993-06-30 | Fisons Plc | Νέαι μακροκυκλικαί ενώσεις και νέα μέ?οδος χρήσεως τους. |
| US5534520A (en) * | 1990-04-10 | 1996-07-09 | Fisher; Abraham | Spiro compounds containing five-membered rings |
| US5541193A (en) * | 1991-09-05 | 1996-07-30 | Abbott Laboratories | Heterocycle-containing macrocyclic immunomodulators |
| GB9202196D0 (en) * | 1992-02-01 | 1992-03-18 | Fisons Plc | Method of treatment |
| GB9218027D0 (en) * | 1992-08-25 | 1992-10-14 | Fisons Plc | Novel method of treatment |
| US5696135A (en) * | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
| US5968921A (en) * | 1997-10-24 | 1999-10-19 | Orgegon Health Sciences University | Compositions and methods for promoting nerve regeneration |
| GB9917158D0 (en) * | 1999-07-21 | 1999-09-22 | Fujisawa Pharmaceutical Co | New use |
-
2001
- 2001-12-27 AR ARP010106058A patent/AR035411A1/es unknown
- 2001-12-31 PL PL01366301A patent/PL366301A1/xx not_active Application Discontinuation
- 2001-12-31 WO PCT/US2001/050419 patent/WO2002053159A1/en not_active Ceased
- 2001-12-31 NZ NZ527209A patent/NZ527209A/en unknown
- 2001-12-31 CN CNB018228860A patent/CN1293877C/zh not_active Expired - Fee Related
- 2001-12-31 KR KR1020077003889A patent/KR20070030331A/ko not_active Ceased
- 2001-12-31 IL IL15666401A patent/IL156664A0/xx unknown
- 2001-12-31 RU RU2003123493/15A patent/RU2288716C2/ru not_active IP Right Cessation
- 2001-12-31 EP EP01991558A patent/EP1353671A4/en not_active Withdrawn
- 2001-12-31 BR BR0116762-6A patent/BR0116762A/pt not_active Application Discontinuation
- 2001-12-31 CA CA002433384A patent/CA2433384A1/en not_active Abandoned
- 2001-12-31 AU AU2002231277A patent/AU2002231277B2/en not_active Ceased
- 2001-12-31 KR KR1020037008787A patent/KR100794204B1/ko not_active Expired - Fee Related
- 2001-12-31 HU HU0302521A patent/HUP0302521A3/hu unknown
- 2001-12-31 CZ CZ20032060A patent/CZ20032060A3/cs unknown
- 2001-12-31 MX MXPA03005941A patent/MXPA03005941A/es active IP Right Grant
- 2001-12-31 JP JP2002554109A patent/JP2004527472A/ja not_active Ceased
-
2003
- 2003-06-24 NO NO20032913A patent/NO20032913D0/no not_active Application Discontinuation
- 2003-07-28 ZA ZA2003/05806A patent/ZA200305806B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100794204B1 (ko) | 2008-01-14 |
| NO20032913D0 (no) | 2003-06-24 |
| IL156664A0 (en) | 2004-01-04 |
| CZ20032060A3 (cs) | 2004-01-14 |
| BR0116762A (pt) | 2004-08-10 |
| NZ527209A (en) | 2005-09-30 |
| RU2288716C2 (ru) | 2006-12-10 |
| RU2003123493A (ru) | 2005-01-20 |
| CA2433384A1 (en) | 2002-07-11 |
| EP1353671A4 (en) | 2004-07-14 |
| AU2002231277B2 (en) | 2006-11-30 |
| HUP0302521A2 (hu) | 2003-11-28 |
| CN1293877C (zh) | 2007-01-10 |
| WO2002053159A1 (en) | 2002-07-11 |
| ZA200305806B (en) | 2005-01-26 |
| HUP0302521A3 (en) | 2007-03-28 |
| EP1353671A1 (en) | 2003-10-22 |
| JP2004527472A (ja) | 2004-09-09 |
| MXPA03005941A (es) | 2005-02-14 |
| PL366301A1 (en) | 2005-01-24 |
| CN1538843A (zh) | 2004-10-20 |
| KR20040007431A (ko) | 2004-01-24 |
| KR20070030331A (ko) | 2007-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |