AR022462A1 - Uso de un agente que disminuye el colesterol - Google Patents
Uso de un agente que disminuye el colesterolInfo
- Publication number
- AR022462A1 AR022462A1 ARP000100408A ARP000100408A AR022462A1 AR 022462 A1 AR022462 A1 AR 022462A1 AR P000100408 A ARP000100408 A AR P000100408A AR P000100408 A ARP000100408 A AR P000100408A AR 022462 A1 AR022462 A1 AR 022462A1
- Authority
- AR
- Argentina
- Prior art keywords
- agent
- dosages
- oral
- decreases cholesterol
- compound
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- 235000012000 cholesterol Nutrition 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente concierne el uso de dosificaciones orales o rangos de dosificacion oral del compuesto ácido (E)-7-[4-(4-florofenil)-6-isopropil-2-[metil(metilsulfonil)amino]pirimidin-5-il]-(3R,5S)-3,5-dihidroxihept-6-enoico, o de una sal del mismo aceptable para uso farmacéutico, para alterar beneficiosamentelos niveles o las relaciones de lípidos en un paciente humano que lo necesita, así como composiciones farmacéuticas de dicho compuesto o sales adaptadas parala administracion oral que comprendentales dosificaciones, y métodos para su preparacion.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9902590.0A GB9902590D0 (en) | 1999-02-06 | 1999-02-06 | Use of cholesterol-lowering agent |
| GBGB9921062.7A GB9921062D0 (en) | 1999-09-08 | 1999-09-08 | Use of cholestrol-lowering agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR022462A1 true AR022462A1 (es) | 2002-09-04 |
Family
ID=26315084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000100408A AR022462A1 (es) | 1999-02-06 | 2000-01-31 | Uso de un agente que disminuye el colesterol |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1150679A1 (es) |
| JP (2) | JP2002536333A (es) |
| KR (1) | KR100699287B1 (es) |
| CN (1) | CN1347320A (es) |
| AR (1) | AR022462A1 (es) |
| AU (1) | AU769897B2 (es) |
| BR (1) | BR0007991A (es) |
| CA (1) | CA2358641A1 (es) |
| CZ (1) | CZ20012631A3 (es) |
| EE (1) | EE04659B1 (es) |
| HK (1) | HK1040924A1 (es) |
| HU (1) | HUP0105019A3 (es) |
| ID (1) | ID30131A (es) |
| IL (1) | IL144662A0 (es) |
| IS (1) | IS5996A (es) |
| MY (1) | MY136382A (es) |
| NO (1) | NO319827B1 (es) |
| NZ (1) | NZ512681A (es) |
| PL (1) | PL349137A1 (es) |
| SK (1) | SK11112001A3 (es) |
| TR (1) | TR200102236T2 (es) |
| WO (1) | WO2000045819A1 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0001621D0 (en) * | 2000-01-26 | 2000-03-15 | Astrazeneca Ab | Pharmaceutical compositions |
| GB0003305D0 (en) | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
| SE0103509D0 (sv) * | 2001-10-19 | 2001-10-19 | Astrazeneca Ab | Rosuvastatin in pre demented states |
| GB0322552D0 (en) | 2003-09-26 | 2003-10-29 | Astrazeneca Uk Ltd | Therapeutic treatment |
| WO2007142581A1 (en) * | 2006-06-07 | 2007-12-13 | Astrazeneca Ab | Combination product for the treatment or prevention of dyslipidaemia |
| CA2689575A1 (en) | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | Cetp inhibitors derived from benzoxazole arylamides |
| AU2008266956A1 (en) | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | CETP inhibitors derived from benzoxazole arylamides |
| AU2008266957A1 (en) * | 2007-06-20 | 2008-12-24 | Merck Sharp & Dohme Corp. | CETP inhibitors derived from benzoxazole arylamides |
| EP2216095A1 (en) * | 2009-01-27 | 2010-08-11 | Koninklijke Philips Electronics N.V. | Microfluidic device for full blood count |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260446A (en) * | 1989-12-22 | 1993-11-09 | Basf Aktiengesellschaft | Aminothiazoles |
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
-
2000
- 2000-01-31 AR ARP000100408A patent/AR022462A1/es unknown
- 2000-02-01 CZ CZ20012631A patent/CZ20012631A3/cs unknown
- 2000-02-01 ID IDW00200101666A patent/ID30131A/id unknown
- 2000-02-01 HK HK02102713.0A patent/HK1040924A1/zh unknown
- 2000-02-01 HU HU0105019A patent/HUP0105019A3/hu unknown
- 2000-02-01 IL IL14466200A patent/IL144662A0/xx unknown
- 2000-02-01 EP EP00901748A patent/EP1150679A1/en not_active Withdrawn
- 2000-02-01 TR TR2001/02236T patent/TR200102236T2/xx unknown
- 2000-02-01 JP JP2000596939A patent/JP2002536333A/ja not_active Withdrawn
- 2000-02-01 NZ NZ512681A patent/NZ512681A/en not_active IP Right Cessation
- 2000-02-01 PL PL00349137A patent/PL349137A1/xx not_active Application Discontinuation
- 2000-02-01 CA CA002358641A patent/CA2358641A1/en not_active Abandoned
- 2000-02-01 SK SK1111-2001A patent/SK11112001A3/sk not_active Application Discontinuation
- 2000-02-01 AU AU23051/00A patent/AU769897B2/en not_active Revoked
- 2000-02-01 BR BR0007991-0A patent/BR0007991A/pt not_active Application Discontinuation
- 2000-02-01 EE EEP200100404A patent/EE04659B1/xx not_active IP Right Cessation
- 2000-02-01 KR KR1020017009822A patent/KR100699287B1/ko not_active Ceased
- 2000-02-01 CN CN00803519A patent/CN1347320A/zh active Pending
- 2000-02-01 WO PCT/GB2000/000285 patent/WO2000045819A1/en not_active Ceased
- 2000-02-04 MY MYPI20000415A patent/MY136382A/en unknown
-
2001
- 2001-07-10 IS IS5996A patent/IS5996A/is unknown
- 2001-08-03 NO NO20013810A patent/NO319827B1/no active IP Right Review Request
-
2011
- 2011-02-22 JP JP2011035406A patent/JP2011137023A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2358641A1 (en) | 2000-08-10 |
| EE04659B1 (et) | 2006-08-15 |
| AU769897B2 (en) | 2004-02-05 |
| TR200102236T2 (tr) | 2001-12-21 |
| HUP0105019A2 (hu) | 2002-05-29 |
| CN1347320A (zh) | 2002-05-01 |
| MY136382A (en) | 2008-09-30 |
| HUP0105019A3 (en) | 2003-02-28 |
| KR100699287B1 (ko) | 2007-03-26 |
| NO20013810D0 (no) | 2001-08-03 |
| NO319827B1 (no) | 2005-09-19 |
| HK1040924A1 (zh) | 2002-06-28 |
| PL349137A1 (en) | 2002-07-01 |
| ID30131A (id) | 2001-11-08 |
| CZ20012631A3 (cs) | 2001-10-17 |
| IL144662A0 (en) | 2002-05-23 |
| EE200100404A (et) | 2002-10-15 |
| AU2305100A (en) | 2000-08-25 |
| EP1150679A1 (en) | 2001-11-07 |
| WO2000045819A1 (en) | 2000-08-10 |
| JP2002536333A (ja) | 2002-10-29 |
| JP2011137023A (ja) | 2011-07-14 |
| SK11112001A3 (sk) | 2002-02-05 |
| NZ512681A (en) | 2003-12-19 |
| BR0007991A (pt) | 2001-11-06 |
| NO20013810L (no) | 2001-10-03 |
| KR20010089631A (ko) | 2001-10-06 |
| IS5996A (is) | 2001-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |