DE69940557D1 - Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung - Google Patents
Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzungInfo
- Publication number
- DE69940557D1 DE69940557D1 DE69940557T DE69940557T DE69940557D1 DE 69940557 D1 DE69940557 D1 DE 69940557D1 DE 69940557 T DE69940557 T DE 69940557T DE 69940557 T DE69940557 T DE 69940557T DE 69940557 D1 DE69940557 D1 DE 69940557D1
- Authority
- DE
- Germany
- Prior art keywords
- present
- cellulose ether
- hydrocolloid
- tablet
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920003086 cellulose ether Polymers 0.000 title abstract 5
- 239000000416 hydrocolloid Substances 0.000 title abstract 4
- 238000013268 sustained release Methods 0.000 abstract 3
- 239000012730 sustained-release form Substances 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 229920002907 Guar gum Polymers 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- 239000000665 guar gum Substances 0.000 abstract 1
- 235000010417 guar gum Nutrition 0.000 abstract 1
- 229960002154 guar gum Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 239000000230 xanthan gum Substances 0.000 abstract 1
- 235000010493 xanthan gum Nutrition 0.000 abstract 1
- 229920001285 xanthan gum Polymers 0.000 abstract 1
- 229940082509 xanthan gum Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11196498P | 1998-12-11 | 1998-12-11 | |
| PCT/US1999/029372 WO2000033818A1 (en) | 1998-12-11 | 1999-12-10 | Sustained release tablet containing hydrocolloid and cellulose ether |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE69940557D1 true DE69940557D1 (de) | 2009-04-23 |
Family
ID=22341399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69940557T Expired - Lifetime DE69940557D1 (de) | 1998-12-11 | 1999-12-10 | Ein hydrokolloid und einen celluloseether enthaltende tablette mit verzögerter freisetzung |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6416786B1 (de) |
| EP (1) | EP1137403B1 (de) |
| JP (1) | JP2002531491A (de) |
| AT (1) | ATE424810T1 (de) |
| AU (1) | AU772891B2 (de) |
| CA (1) | CA2354057C (de) |
| DE (1) | DE69940557D1 (de) |
| NZ (1) | NZ512288A (de) |
| WO (1) | WO2000033818A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19933289A1 (de) * | 1999-07-15 | 2001-01-18 | Basf Ag | Verfahren zur Herstellung eines Granulats aus einer Schmelze |
| US7838032B2 (en) | 2000-04-28 | 2010-11-23 | Reckitt Benckiser Inc. | Sustained release of guaifenesin |
| US7985420B2 (en) | 2000-04-28 | 2011-07-26 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| US6955821B2 (en) | 2000-04-28 | 2005-10-18 | Adams Laboratories, Inc. | Sustained release formulations of guaifenesin and additional drug ingredients |
| US8012504B2 (en) | 2000-04-28 | 2011-09-06 | Reckitt Benckiser Inc. | Sustained release of guaifenesin combination drugs |
| AU2002248792B2 (en) * | 2001-04-18 | 2006-09-21 | Nostrum Pharmaceuticals Inc. | A novel coating for a sustained release pharmaceutical composition |
| US20020198209A1 (en) | 2001-05-03 | 2002-12-26 | Allergan Sales Inc. | Compositions having enhanced pharmacokinetic characteristics |
| MXPA04010225A (es) * | 2002-04-15 | 2005-07-05 | Adams Lab Inc | Liberacion sostenida de la combinacion de guaifenesina con farmacos. |
| KR100548925B1 (ko) * | 2002-10-23 | 2006-02-02 | 한미약품 주식회사 | 약물의 경구투여용 서방성 조성물 |
| DE60314441T2 (de) * | 2002-11-04 | 2008-02-21 | Transform Pharmaceuticals, Inc., Lexington | Analyse pharmazeutischer löslichkeit und stabilität |
| NZ542303A (en) * | 2003-03-14 | 2008-12-24 | Nirmal Mulye | A process for preparing sustained release tablets |
| CA2533165A1 (en) * | 2003-07-21 | 2005-01-27 | Bio-Dar Ltd. | Gellan gum based oral controlled release dosage forms- a novel platform technology for gastric retention |
| US7163101B2 (en) * | 2003-10-30 | 2007-01-16 | William Anthony Harper | Flexible liquid packet with rigid insert |
| FR2861990B1 (fr) | 2003-11-10 | 2006-02-10 | Nouveaux Produits Pharma | Comprimes faiblement doses a reseau de polymeres |
| US20050202079A1 (en) * | 2004-03-15 | 2005-09-15 | Mylan Pharmaceuticals Inc. | Novel orally administrable formulation of nitrofurantoin and a method for preparing said formulation |
| WO2006129966A1 (en) * | 2005-05-31 | 2006-12-07 | Ctc Bio, Inc. | Manufacturing method of controlled-release tablet containing doxazocin mesylate |
| US20070141147A1 (en) * | 2005-12-21 | 2007-06-21 | Auriga Laboratories, Inc. | Sequential release pharmaceutical formulations |
| CA2569776A1 (en) * | 2006-02-17 | 2007-08-17 | Kos Life Sciences, Inc. | Low flush niacin formulation |
| US20080064694A1 (en) * | 2006-09-11 | 2008-03-13 | Auriga Laboratories, Inc. | Multi-Phase Release Methscopolamine Compositions |
| WO2008033155A1 (en) * | 2006-09-15 | 2008-03-20 | Auriga Laboratories, Inc. | Kits for prevention and treatment of rhinitis |
| US20080085312A1 (en) * | 2006-10-04 | 2008-04-10 | Auriga Laboratories, Inc. | Multi-Phase Release Potassium Guaiacolsulfonate Compositions |
| KR100836960B1 (ko) * | 2007-09-07 | 2008-06-10 | 주식회사 서울제약 | 새로운 나이아신 제어방출형 제제 |
| RU2363464C2 (ru) * | 2007-09-18 | 2009-08-10 | Закрытое Акционерное Общество "Канонфарма Продакшн" | Таблетированная лекарственная форма фелодипина с модифицированным высвобождением, способ ее получения, композиция для ее изготовления и медицинское применение |
| US20090202633A1 (en) * | 2008-01-03 | 2009-08-13 | Siva Ramakrishna Velaga | Extended release formulations of guaifenesin |
| DK2548456T3 (en) | 2008-03-20 | 2015-09-28 | Virun Inc | Emulsions including (comprising) a PEG derivative of tocopherol |
| BRPI0909185A2 (pt) | 2008-03-20 | 2015-08-25 | Virun Inc | Derivado de vitamina e e seus usos |
| US20100159001A1 (en) * | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| US20100160363A1 (en) * | 2008-12-19 | 2010-06-24 | Aaipharma Services Corp. | Extended-release pharmaceutical formulations |
| KR101622441B1 (ko) * | 2010-03-23 | 2016-05-18 | 버런, 아이엔씨. | 자당 지방산 에스테르를 포함하는 나노에멀전 |
| US9351517B2 (en) | 2013-03-15 | 2016-05-31 | Virun, Inc. | Formulations of water-soluble derivatives of vitamin E and compositions containing same |
| GB201506755D0 (en) | 2015-04-21 | 2015-06-03 | Reckitt Benckiser Llc | Novel pharmaceutical formulation |
| WO2017062997A1 (en) | 2015-10-09 | 2017-04-13 | Reckitt Benckiser Llc | Pharmaceutical formulation |
| KR102329377B1 (ko) * | 2017-02-03 | 2021-11-19 | 가부시키가이샤 도요 신야쿠 | 고형 제제 |
| EP3511266A1 (de) * | 2018-01-15 | 2019-07-17 | Axel Nickel | Getränkepulver und füllstoff enthaltende kapsel, insbesondere zur zubereitung von gebrühtem kaffee |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4369172A (en) | 1981-12-18 | 1983-01-18 | Forest Laboratories Inc. | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose |
| US4795327A (en) | 1984-03-26 | 1989-01-03 | Forest Laboratories, Inc. | Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants |
| JPS6124516A (ja) | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
| US4610870A (en) | 1984-10-05 | 1986-09-09 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| EP0272265B1 (de) | 1985-09-25 | 1991-05-22 | Gergely, Gerhard, Dr. | Zerfallstablette und verfahren zu ihrer herstellung |
| US4734285A (en) | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
| US4704285A (en) | 1985-11-18 | 1987-11-03 | The Dow Chemical Company | Sustained release compositions comprising hydroxypropyl cellulose ethers |
| GB8601204D0 (en) | 1986-01-18 | 1986-02-19 | Boots Co Plc | Therapeutic agents |
| GB2186485B (en) | 1986-02-13 | 1988-09-07 | Ethical Pharma Ltd | Slow release formulation |
| IT1191674B (it) * | 1986-03-07 | 1988-03-23 | Eurand Spa | Formulazioni per la preparazione di farmaci a rilascio prolungato adatte alla somministrazione per via orale |
| US4855143A (en) | 1986-04-04 | 1989-08-08 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4775535A (en) | 1986-04-04 | 1988-10-04 | Hans Lowey | Method of preparing controlled long-acting pharmaceutical formulations in unit dosage form having uniform and comparable bioavailability characteristics |
| US4752479A (en) | 1986-05-27 | 1988-06-21 | Ciba-Geigy Corporaton | Multi vitamin and mineral dietary supplement with controlled release bioavailable iron |
| GB8713169D0 (en) | 1987-06-05 | 1987-07-08 | Peters T J | Uptake of iron by body |
| GB8702411D0 (en) | 1987-02-03 | 1987-03-11 | Zyma Sa | Swellable pellets |
| US4786518A (en) | 1987-07-02 | 1988-11-22 | The Procter & Gamble Company | Iron mineral supplements |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US4994276A (en) | 1988-09-19 | 1991-02-19 | Edward Mendell Co., Inc. | Directly compressible sustained release excipient |
| IE60311B1 (en) | 1987-09-24 | 1994-06-29 | American Home Prod | Sustained release etodolac |
| SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
| DE3809625A1 (de) | 1988-03-22 | 1989-10-05 | Verla Pharm | Oral verabreichbares pharmazeutisches mittel, insbesondere zur eisen- und magnesiumsubstitutionstherapie |
| US5006346A (en) | 1988-04-28 | 1991-04-09 | Alza Corporation | Delivery system |
| US5169639A (en) * | 1988-09-19 | 1992-12-08 | Edward Mendell Co., Inc. | Controlled release verapamil tablets |
| US5128143A (en) | 1988-09-19 | 1992-07-07 | Edward Mendell Co., Inc. | Sustained release excipient and tablet formulation |
| US5135757A (en) | 1988-09-19 | 1992-08-04 | Edward Mendell Co., Inc. | Compressible sustained release solid dosage forms |
| US5126145A (en) | 1989-04-13 | 1992-06-30 | Upsher Smith Laboratories Inc | Controlled release tablet containing water soluble medicament |
| US5002774A (en) | 1989-06-08 | 1991-03-26 | Erbamont, Inc. | Sustained release pharmaceutical tablet |
| US4973470A (en) | 1989-06-26 | 1990-11-27 | Warner-Lambert Company | Sustained release pharmaceutical compositions |
| US5077051A (en) | 1990-04-10 | 1991-12-31 | Warner-Lambert Company | Sustained release of active agents from bioadhesive microcapsules |
| JPH0482826A (ja) * | 1990-07-26 | 1992-03-16 | Shin Etsu Chem Co Ltd | 徐放性錠剤 |
| DE69107461T2 (de) | 1990-08-07 | 1995-06-22 | Pfizer | Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen. |
| US5204116A (en) | 1991-05-01 | 1993-04-20 | Alza Corporation | Dosage form providing immediate therapy followed by prolonged therapy |
| US5223268A (en) | 1991-05-16 | 1993-06-29 | Sterling Drug, Inc. | Low solubility drug-coated bead compositions |
| IT1251153B (it) * | 1991-08-06 | 1995-05-04 | Vectorpharma Int | Composizioni farmaceutiche solide per somministrazione orale aventi proungata residenza gastrica |
| JP2669446B2 (ja) | 1992-03-23 | 1997-10-27 | 信越化学工業株式会社 | 医薬品コーティング液用原料粉粒体 |
| US5292534A (en) | 1992-03-25 | 1994-03-08 | Valentine Enterprises, Inc. | Sustained release composition and method utilizing xanthan gum and an active ingredient |
| US5582837A (en) | 1992-03-25 | 1996-12-10 | Depomed, Inc. | Alkyl-substituted cellulose-based sustained-release oral drug dosage forms |
| US5472711A (en) | 1992-07-30 | 1995-12-05 | Edward Mendell Co., Inc. | Agglomerated hydrophilic complexes with multi-phasic release characteristics |
| SE9301220D0 (sv) | 1993-04-14 | 1993-04-14 | Kabi Pharmacia Ab | Manufacturing matrices |
| IT1264696B1 (it) | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
| US5662933A (en) | 1993-09-09 | 1997-09-02 | Edward Mendell Co., Inc. | Controlled release formulation (albuterol) |
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
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| HU213407B (en) | 1993-12-09 | 1997-06-30 | Egyt Gyogyszervegyeszeti Gyar | Process for producing tablet with diffusive-osmotic release |
| US5419917A (en) | 1994-02-14 | 1995-05-30 | Andrx Pharmaceuticals, Inc. | Controlled release hydrogel formulation |
| DE19509807A1 (de) | 1995-03-21 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von Wirkstoffzubereitungen in Form einer festen Lösung des Wirkstoffs in einer Polymermatrix sowie mit diesem Verfahren hergestellte Wirkstoffzubereitungen |
| US5464633A (en) | 1994-05-24 | 1995-11-07 | Jagotec Ag | Pharmaceutical tablets releasing the active substance after a definite period of time |
| US5700832A (en) | 1994-10-19 | 1997-12-23 | Daewon Pharm. Co., Ltd. | Antianemic agent containing iron and difructose |
| IL139728A (en) | 1995-01-09 | 2003-06-24 | Penwest Pharmaceuticals Compan | Aqueous slurry composition containing microcrystalline cellulose for preparing a pharmaceutical excipient |
| US5612053A (en) | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
| US5811126A (en) | 1995-10-02 | 1998-09-22 | Euro-Celtique, S.A. | Controlled release matrix for pharmaceuticals |
| IT1282650B1 (it) | 1996-02-19 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici |
| CA2173818A1 (fr) | 1996-04-10 | 1997-10-11 | Francois Chouinard | Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose |
| US5895663A (en) | 1997-07-31 | 1999-04-20 | L. Perrigo Company | Pseudoephedrine hydrochloride extended-release tablets |
| US5851555A (en) | 1997-08-15 | 1998-12-22 | Fuisz Technologies Ltd. | Controlled release dosage forms containing water soluble drugs |
-
1999
- 1999-12-10 EP EP99968872A patent/EP1137403B1/de not_active Expired - Lifetime
- 1999-12-10 JP JP2000586311A patent/JP2002531491A/ja active Pending
- 1999-12-10 AT AT99968872T patent/ATE424810T1/de not_active IP Right Cessation
- 1999-12-10 US US09/459,300 patent/US6416786B1/en not_active Expired - Lifetime
- 1999-12-10 CA CA002354057A patent/CA2354057C/en not_active Expired - Fee Related
- 1999-12-10 AU AU27079/00A patent/AU772891B2/en not_active Ceased
- 1999-12-10 WO PCT/US1999/029372 patent/WO2000033818A1/en not_active Ceased
- 1999-12-10 DE DE69940557T patent/DE69940557D1/de not_active Expired - Lifetime
- 1999-12-10 NZ NZ512288A patent/NZ512288A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU772891B2 (en) | 2004-05-13 |
| EP1137403A4 (de) | 2005-10-26 |
| US6416786B1 (en) | 2002-07-09 |
| CA2354057A1 (en) | 2000-06-15 |
| CA2354057C (en) | 2009-02-10 |
| AU2707900A (en) | 2000-06-26 |
| ATE424810T1 (de) | 2009-03-15 |
| EP1137403A1 (de) | 2001-10-04 |
| JP2002531491A (ja) | 2002-09-24 |
| EP1137403B1 (de) | 2009-03-11 |
| NZ512288A (en) | 2003-09-26 |
| WO2000033818A9 (en) | 2001-02-01 |
| WO2000033818A1 (en) | 2000-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: NOSTRUM PHARMACEUTICALS INC., EDISON, N.J., US |
|
| 8364 | No opposition during term of opposition |