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AR020300A1 - Procedimiento para preparar sertralina a partir de tetralona quiral. - Google Patents

Procedimiento para preparar sertralina a partir de tetralona quiral.

Info

Publication number
AR020300A1
AR020300A1 ARP000102832A ARP000102832A AR020300A1 AR 020300 A1 AR020300 A1 AR 020300A1 AR P000102832 A ARP000102832 A AR P000102832A AR P000102832 A ARP000102832 A AR P000102832A AR 020300 A1 AR020300 A1 AR 020300A1
Authority
AR
Argentina
Prior art keywords
procedure
chiral tetralone
sertraline
prepare
prepare sertraline
Prior art date
Application number
ARP000102832A
Other languages
English (en)
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of AR020300A1 publication Critical patent/AR020300A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Este invento se refiere a un procedimiento nuevo y mejorado para preparar el enantiomero (+) de la N-[4-(3,4-diclorofenil)-3,4-dihidro-1 (2H)-naftaleniliden]metanamina haciendo reaccionar el enantiomero (+) de la 4-(3,4-diclorofenil)-3,4-dihidro-1 (2H)-naftalenona con monometilamina y con cloruro detitanio o tamices moleculares.
ARP000102832A 1999-06-09 2000-06-07 Procedimiento para preparar sertralina a partir de tetralona quiral. AR020300A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13834099P 1999-06-09 1999-06-09

Publications (1)

Publication Number Publication Date
AR020300A1 true AR020300A1 (es) 2002-05-02

Family

ID=22481595

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000102832A AR020300A1 (es) 1999-06-09 2000-06-07 Procedimiento para preparar sertralina a partir de tetralona quiral.

Country Status (16)

Country Link
US (1) US6593496B1 (es)
EP (1) EP1059287A1 (es)
JP (1) JP3529703B2 (es)
KR (1) KR20010066820A (es)
CN (1) CN1277188A (es)
AR (1) AR020300A1 (es)
AU (1) AU767319B2 (es)
BR (1) BR0002606A (es)
CA (1) CA2310799C (es)
HU (1) HUP0002229A3 (es)
ID (1) ID26278A (es)
IL (1) IL136513A (es)
PL (1) PL340620A1 (es)
RU (1) RU2181358C2 (es)
TR (1) TR200001657A2 (es)
YU (1) YU32700A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK14212002A3 (sk) * 2000-03-14 2003-07-01 Teva Pharmaceutical Industries Ltd. Spôsob prípravy (+)-cis-sertralínu
US20030013768A1 (en) * 2001-05-31 2003-01-16 Orion Coproration Fermion Process for the production of sertraline and intermediates useful therefor
WO2002096860A1 (en) * 2001-05-31 2002-12-05 Orion Corporation Fermion Process for preparing sertraline intermediates
US6723878B2 (en) 2001-06-15 2004-04-20 Orion Corporation Fermion Method for preparing sertraline
AU2002311059A1 (en) * 2002-05-10 2003-12-12 Jaroslav Frantisek Process for the manufacture of sertraline
WO2004041773A1 (en) * 2002-11-07 2004-05-21 Sunil Sadanand Nadkarni Process for preparation of polymorphic form of sertraline hydrochloride
DE04750154T1 (de) * 2003-04-14 2005-12-29 Teva Pharmaceutical Industries Ltd. Katalytische hydrierung von iminzwischenprodukten von sertralin
HU227495B1 (en) * 2003-07-21 2011-07-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Process for producing of imine intermediate
US7345201B2 (en) * 2005-02-23 2008-03-18 Teva Pharmaceutical Industries, Ltd. Processes for preparing sertraline
CA2576097C (en) * 2005-06-03 2009-10-27 Hetero Drugs Limited A highly stereoselective synthesis of sertraline
GB0526444D0 (en) * 2005-12-23 2006-02-08 Sandoz Ag Sertraline acid addition salt, its prepartion and its use in the preparation of sertraline hydrochloride form ll
US10266481B2 (en) * 2014-06-20 2019-04-23 Council Of Scientific & Industrial Research Organocatalytic asymmetric synthesis of antidepressants
CN115707683A (zh) * 2021-08-18 2023-02-21 浙江华海药业股份有限公司 一种制备舍曲林中间体的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536518A (en) 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
US4855500A (en) 1988-05-04 1989-08-08 Pfizer Inc. Process for preparing a ketimine
US5356905A (en) * 1990-02-06 1994-10-18 Pfizer Inc. Neuroprotective 3-piperidino-4-hydroxychroman derivatives and analogs
US5196607A (en) * 1992-02-14 1993-03-23 Pfizer Inc. Process for preparing ketone enantiomer
HU226423B1 (en) 1998-05-05 2008-12-29 Egis Gyogyszergyar Nyrt Process for producing a 1(2h)-naphtalene-1-ylidene derivative

Also Published As

Publication number Publication date
RU2181358C2 (ru) 2002-04-20
CN1277188A (zh) 2000-12-20
TR200001657A2 (tr) 2001-01-22
BR0002606A (pt) 2001-01-02
KR20010066820A (ko) 2001-07-11
CA2310799C (en) 2004-05-04
EP1059287A1 (en) 2000-12-13
ID26278A (id) 2000-12-14
HU0002229D0 (en) 2000-08-28
JP3529703B2 (ja) 2004-05-24
US6593496B1 (en) 2003-07-15
HUP0002229A2 (hu) 2002-04-29
CA2310799A1 (en) 2000-12-09
AU767319B2 (en) 2003-11-06
JP2000351758A (ja) 2000-12-19
YU32700A (sh) 2002-03-18
HUP0002229A3 (en) 2003-05-28
AU3934500A (en) 2000-12-14
IL136513A0 (en) 2001-06-14
PL340620A1 (en) 2000-12-18
IL136513A (en) 2006-06-11

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