AU2002311059A1 - Process for the manufacture of sertraline - Google Patents
Process for the manufacture of sertralineInfo
- Publication number
- AU2002311059A1 AU2002311059A1 AU2002311059A AU2002311059A AU2002311059A1 AU 2002311059 A1 AU2002311059 A1 AU 2002311059A1 AU 2002311059 A AU2002311059 A AU 2002311059A AU 2002311059 A AU2002311059 A AU 2002311059A AU 2002311059 A1 AU2002311059 A1 AU 2002311059A1
- Authority
- AU
- Australia
- Prior art keywords
- sertraline
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- VGKDLMBJGBXTGI-SJCJKPOMSA-N sertraline Chemical compound C1([C@@H]2CC[C@@H](C3=CC=CC=C32)NC)=CC=C(Cl)C(Cl)=C1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 0.000 title 1
- 229960002073 sertraline Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/24—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
- C07C209/28—Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with other reducing agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CZ2002/000028 WO2003099761A1 (en) | 2002-05-10 | 2002-05-10 | Process for the manufacture of sertraline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2002311059A1 true AU2002311059A1 (en) | 2003-12-12 |
Family
ID=29555563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002311059A Abandoned AU2002311059A1 (en) | 2002-05-10 | 2002-05-10 | Process for the manufacture of sertraline |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1503978A1 (en) |
| AU (1) | AU2002311059A1 (en) |
| CA (1) | CA2485499A1 (en) |
| HU (1) | HUP0500215A2 (en) |
| WO (1) | WO2003099761A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507090D0 (en) | 2005-04-07 | 2005-05-11 | Sandoz Ag | Process for preparing polymorphic form ll of sertraline hydrochloride |
| CA2576097C (en) | 2005-06-03 | 2009-10-27 | Hetero Drugs Limited | A highly stereoselective synthesis of sertraline |
| WO2007119247A2 (en) * | 2006-04-17 | 2007-10-25 | Unichem Laboratories Limited | Improved manufacturing procedure for the preparation of polymorphic form ii of cis-(1s)-n-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthleneamine hydrochloride (sertraline hydrochloride) |
| CN104876812B (en) * | 2015-05-20 | 2020-12-08 | 浙江华海药业股份有限公司 | Process for preparing sertraline hydrochloride intermediates and impurities |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4855500A (en) * | 1988-05-04 | 1989-08-08 | Pfizer Inc. | Process for preparing a ketimine |
| FR2777000B1 (en) * | 1998-04-01 | 2002-09-27 | Catalys | PROCESS FOR THE PREPARATION OF RACEMIC SERTRALINE |
| HU226423B1 (en) * | 1998-05-05 | 2008-12-29 | Egis Gyogyszergyar Nyrt | Process for producing a 1(2h)-naphtalene-1-ylidene derivative |
| US6593496B1 (en) * | 1999-06-09 | 2003-07-15 | Pfizer Inc | Process for preparing sertraline from chiral tetralone |
-
2002
- 2002-05-10 CA CA002485499A patent/CA2485499A1/en not_active Abandoned
- 2002-05-10 HU HU0500215A patent/HUP0500215A2/en unknown
- 2002-05-10 WO PCT/CZ2002/000028 patent/WO2003099761A1/en not_active Ceased
- 2002-05-10 EP EP02734991A patent/EP1503978A1/en not_active Withdrawn
- 2002-05-10 AU AU2002311059A patent/AU2002311059A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2485499A1 (en) | 2003-12-04 |
| EP1503978A1 (en) | 2005-02-09 |
| HUP0500215A2 (en) | 2005-06-28 |
| WO2003099761A1 (en) | 2003-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |