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AR029806A1 - Derivados de fenilo, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de la composicion farmaceutica y usos de estos derivados - Google Patents

Derivados de fenilo, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de la composicion farmaceutica y usos de estos derivados

Info

Publication number
AR029806A1
AR029806A1 ARP010100842A ARP010100842A AR029806A1 AR 029806 A1 AR029806 A1 AR 029806A1 AR P010100842 A ARP010100842 A AR P010100842A AR P010100842 A ARP010100842 A AR P010100842A AR 029806 A1 AR029806 A1 AR 029806A1
Authority
AR
Argentina
Prior art keywords
preparation
pharmaceutical composition
derivatives
phenyle
activity
Prior art date
Application number
ARP010100842A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0000620A external-priority patent/SE0000620D0/xx
Priority claimed from SE0002234A external-priority patent/SE0002234D0/xx
Priority claimed from SE0003979A external-priority patent/SE0003979D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR029806A1 publication Critical patent/AR029806A1/es

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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Abstract

Derivados de fenilo de la formula general 1 donde Q, R, R2, R4, R5, R6, R7 y R8 son como se definieron en la memoria descriptiva, proceso para su preparacion, composicion farmacéutica que los contienen, proceso para la preparacion de la composicion farmacéutica y usos de los derivados. Estos compuestos tienen actividad farmacéutica, en particular como modulares de la actividad de la quimioquina MIP 1 alfa y pueden ser especialmente usados en el tratamiento de la esclerosis multiple.
ARP010100842A 2000-02-25 2001-02-23 Derivados de fenilo, proceso para su preparacion, composicion farmaceutica, proceso para la preparacion de la composicion farmaceutica y usos de estos derivados AR029806A1 (es)

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SE0000620A SE0000620D0 (sv) 2000-02-25 2000-02-25 Novel compounds
SE0002234A SE0002234D0 (sv) 2000-06-14 2000-06-14 Novel compounds
SE0003979A SE0003979D0 (sv) 2000-10-31 2000-10-31 Novel Compounds

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