AR029250A1 - Derivados de milbemicina, composicion que los comprende y el uso de los mismos para la elaboracion de un medicamento contra insectos y otras plagas. - Google Patents
Derivados de milbemicina, composicion que los comprende y el uso de los mismos para la elaboracion de un medicamento contra insectos y otras plagas.Info
- Publication number
- AR029250A1 AR029250A1 ARP010102004A ARP010102004A AR029250A1 AR 029250 A1 AR029250 A1 AR 029250A1 AR P010102004 A ARP010102004 A AR P010102004A AR P010102004 A ARP010102004 A AR P010102004A AR 029250 A1 AR029250 A1 AR 029250A1
- Authority
- AR
- Argentina
- Prior art keywords
- derivatives
- preparation
- composition
- milbemicine
- pests
- Prior art date
Links
- 241000238631 Hexapoda Species 0.000 title 1
- 241000282414 Homo sapiens Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000006661 (C4-C6) heterocyclic group Chemical group 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000000895 acaricidal effect Effects 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 230000000749 insecticidal effect Effects 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- FXWHFKOXMBTCMP-WMEDONTMSA-N milbemycin Natural products COC1C2OCC3=C/C=C/C(C)CC(=CCC4CC(CC5(O4)OC(C)C(C)C(OC(=O)C(C)CC(C)C)C5O)OC(=O)C(C=C1C)C23O)C FXWHFKOXMBTCMP-WMEDONTMSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describen derivados de milbemicina que comprenden compuestos de formula (1) y sales de los mismos: en la cual R1 representa metilo, etilo, isopropilo o s-butilo; R2 representa hidrogeno o alquilo, R3 representa hidrogeno, opcionalmente alcanoilo sustituido, alquilsulfonilo, o alcoxicarbonilo, o R2 y R3 junto con el átomo de nitrogeno al cual están unidos forman un grupo de anillo heterocíclico de 4 a 6 miembros saturado, opcionalmente sustituido; y la porcion ûa- junto con el átomo de carbono al cual está unida forman un grupo cicloalquilo de 3 a 6 miembros; estos compuestos tienen actividad antihelmíntica, acaricida e insecticida; una composicion que los comprende y el uso de dichos derivados para la elaboracion de un medicamento para proteger animales, seres humanos o no humanos, del dano por parásitos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000127209 | 2000-04-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR029250A1 true AR029250A1 (es) | 2003-06-18 |
Family
ID=18636847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010102004A AR029250A1 (es) | 2000-04-27 | 2001-04-27 | Derivados de milbemicina, composicion que los comprende y el uso de los mismos para la elaboracion de un medicamento contra insectos y otras plagas. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US6653342B2 (es) |
| EP (1) | EP1276748B1 (es) |
| KR (1) | KR100711931B1 (es) |
| CN (1) | CN1247607C (es) |
| AR (1) | AR029250A1 (es) |
| AT (1) | ATE315573T1 (es) |
| AU (2) | AU2001252613B2 (es) |
| BR (1) | BR0110385A (es) |
| CA (1) | CA2407611A1 (es) |
| CZ (1) | CZ20023565A3 (es) |
| DE (1) | DE60116615T2 (es) |
| DK (1) | DK1276748T3 (es) |
| ES (1) | ES2254400T3 (es) |
| HU (1) | HUP0301040A3 (es) |
| IL (1) | IL152449A0 (es) |
| MX (1) | MXPA02010587A (es) |
| NO (1) | NO323751B1 (es) |
| NZ (1) | NZ522247A (es) |
| PL (1) | PL357598A1 (es) |
| RU (1) | RU2226531C1 (es) |
| TW (1) | TWI285206B (es) |
| WO (1) | WO2001083500A1 (es) |
| ZA (1) | ZA200208630B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04003854A (es) * | 2001-10-25 | 2005-02-17 | Sankyo Lifetech Company Ltd | Composicion antihelmintica. |
| AR045142A1 (es) | 2003-07-30 | 2005-10-19 | Novartis Ag | Composicion veterinaria masticable ductil de buen sabor |
| US20090281175A1 (en) * | 2006-09-28 | 2009-11-12 | Galderma S.A. | Avermectin compounds and treatment of dermatological disorders in humans therewith |
| WO2010065852A1 (en) | 2008-12-04 | 2010-06-10 | Merial Limited | Dimeric avermectin and milbemycin derivatives |
| RU2413513C2 (ru) * | 2009-04-06 | 2011-03-10 | Государственное образовательное учреждение высшего профессионального образования "Казанский государственный университет им. В.И. Ульянова-Ленина" | Антигельминтная композиция на основе соли четвертичного фосфония и замещенного динитробензофуроксана |
| CA2784141C (en) | 2009-12-17 | 2017-10-24 | Merial Limited | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
| PL3351546T3 (pl) | 2011-12-02 | 2024-09-09 | Boehringer Ingelheim Vetmedica Gmbh | Długodziałające wstrzykiwalne postaci moksydektyny |
| NZ712345A (en) | 2013-04-12 | 2016-04-29 | Zoetis Services Llc | Composition of macrocyclic lactones, levamisole, an amino sugar and an additional antiparasitic agent |
| BR112021012171A2 (pt) * | 2018-12-21 | 2021-08-31 | ELANCO US, Inc. | Formulações parasiticidas e uso das mesmas |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4206205A (en) | 1977-10-03 | 1980-06-03 | Merck & Co., Inc. | Monosaccharide and aglycone derivatives of C-076 |
| US4201861A (en) | 1977-10-03 | 1980-05-06 | Merck & Co., Inc. | Acyl derivatives of C-076 compounds |
| NZ188459A (en) | 1977-10-03 | 1982-09-07 | Merck & Co Inc | Derivatives of c-076 compounds and pesticidal compositions |
| US4173571A (en) | 1977-12-19 | 1979-11-06 | Merck & Co., Inc. | 13-Halo and 13-deoxy derivatives of C-076 compounds |
| US4171314A (en) | 1977-12-19 | 1979-10-16 | Merck & Co., Inc. | 13-Halo and 13-deoxy C-076 compounds |
| US4203976A (en) | 1978-08-02 | 1980-05-20 | Merck & Co., Inc. | Sugar derivatives of C-076 compounds |
| US4200581A (en) | 1978-08-04 | 1980-04-29 | Merck & Co., Inc. | Alkyl derivatives of C-076 compounds |
| US4289760A (en) | 1980-05-02 | 1981-09-15 | Merck & Co., Inc. | 23-Keto derivatives of C-076 compounds |
| JPS57120589A (en) | 1981-01-20 | 1982-07-27 | Sankyo Co Ltd | 5-methoxy and 5-lower alkanoyloxy derivative, its preparation and acaricide and parasiticide |
| IT1144368B (it) | 1981-05-20 | 1986-10-29 | Gaudino Di P Gaudino & C Sas O | Perfezionamenti nei laminatoi con almeno un campo di stiro per la filatura diretta di pettinato e semipettinato |
| US4457920A (en) | 1981-09-03 | 1984-07-03 | Merck & Co., Inc. | 4a-Substituted avermectin compounds |
| US4423209A (en) | 1982-02-26 | 1983-12-27 | Merck & Co., Inc. | Processes for the interconversion of avermectin compounds |
| JPS5916894A (ja) | 1982-07-21 | 1984-01-28 | Sankyo Co Ltd | ミルベマイシンｄの５−アシルオキシ誘導体 |
| JPS5920285A (ja) | 1982-07-23 | 1984-02-01 | Sankyo Co Ltd | ミルベマイシンｄの５−二塩基酸エステル誘導体及びその塩 |
| JPS59108785A (ja) | 1982-11-25 | 1984-06-23 | Sankyo Co Ltd | ミルベマイシン類の５−オキシム誘導体 |
| US4469682A (en) | 1983-01-28 | 1984-09-04 | Merck & Co., Inc. | Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use |
| US4579864A (en) | 1984-06-11 | 1986-04-01 | Merck & Co., Inc. | Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives |
| US4547491A (en) | 1984-07-18 | 1985-10-15 | Merck & Co., Inc. | C-8A-Oxo-avermectin and milbemycin derivatives, pharmaceutical compositions and method of use |
| EP0180539A1 (de) | 1984-09-18 | 1986-05-07 | Ciba-Geigy Ag | 13-Halo- und 13-Hydroximilbemycine |
| US4696922A (en) | 1984-11-26 | 1987-09-29 | Ciba-Geigy Corporation | 5-azolylacetoxymilbemycins as ecto- and endoparasites |
| JPS6289685A (ja) | 1985-05-31 | 1987-04-24 | Sankyo Co Ltd | １３−ハロゲンミルベマイシン誘導体 |
| EP0246739B1 (en) * | 1986-03-25 | 1991-01-23 | Sankyo Company Limited | Macrolide compounds, their preparation and their use |
| US5614470A (en) * | 1994-04-01 | 1997-03-25 | Sankyo Company, Limited | 13-substituted milbemycin derivatives, their preparation and their use |
| HU225226B1 (en) | 1995-09-29 | 2006-08-28 | Sankyo Lifetech Company Ltd | 13-substituted milbemycin 5-oxime derivatives, their use, and anthelmintic, acaricide and insecticide compositions containing these compounds |
-
2001
- 2001-04-26 DK DK01925985T patent/DK1276748T3/da active
- 2001-04-26 EP EP01925985A patent/EP1276748B1/en not_active Expired - Lifetime
- 2001-04-26 HU HU0301040A patent/HUP0301040A3/hu unknown
- 2001-04-26 WO PCT/JP2001/003656 patent/WO2001083500A1/en not_active Ceased
- 2001-04-26 CA CA002407611A patent/CA2407611A1/en not_active Abandoned
- 2001-04-26 CN CNB018119832A patent/CN1247607C/zh not_active Expired - Fee Related
- 2001-04-26 CZ CZ20023565A patent/CZ20023565A3/cs unknown
- 2001-04-26 PL PL01357598A patent/PL357598A1/xx unknown
- 2001-04-26 RU RU2002131794/04A patent/RU2226531C1/ru not_active IP Right Cessation
- 2001-04-26 AU AU2001252613A patent/AU2001252613B2/en not_active Ceased
- 2001-04-26 NZ NZ522247A patent/NZ522247A/en unknown
- 2001-04-26 IL IL15244901A patent/IL152449A0/xx unknown
- 2001-04-26 TW TW090109990A patent/TWI285206B/zh not_active IP Right Cessation
- 2001-04-26 DE DE60116615T patent/DE60116615T2/de not_active Expired - Fee Related
- 2001-04-26 KR KR1020027013834A patent/KR100711931B1/ko not_active Expired - Fee Related
- 2001-04-26 MX MXPA02010587A patent/MXPA02010587A/es active IP Right Grant
- 2001-04-26 AU AU5261301A patent/AU5261301A/xx active Pending
- 2001-04-26 AT AT01925985T patent/ATE315573T1/de not_active IP Right Cessation
- 2001-04-26 ES ES01925985T patent/ES2254400T3/es not_active Expired - Lifetime
- 2001-04-26 BR BR0110385-7A patent/BR0110385A/pt not_active IP Right Cessation
- 2001-04-27 AR ARP010102004A patent/AR029250A1/es not_active Application Discontinuation
-
2002
- 2002-10-22 US US10/277,993 patent/US6653342B2/en not_active Expired - Fee Related
- 2002-10-24 ZA ZA200208630A patent/ZA200208630B/en unknown
- 2002-10-25 NO NO20025141A patent/NO323751B1/no not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |