|
CN1196698C
(zh)
|
1996-11-18 |
2005-04-13 |
生物技术研究有限公司(Gbf) |
Epothilone D、E和F,其制备方法,以及作为细胞抑制剂和植物保护剂的应用
|
|
DE69734362T2
(de)
|
1996-12-03 |
2006-07-20 |
Sloan-Kettering Institute For Cancer Research |
Synthese von epothilonen, zwischenprodukte dazu, analoga und verwendungen davon
|
|
US6204388B1
(en)
*
|
1996-12-03 |
2001-03-20 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US6867305B2
(en)
*
|
1996-12-03 |
2005-03-15 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US20050043376A1
(en)
*
|
1996-12-03 |
2005-02-24 |
Danishefsky Samuel J. |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
US20020058286A1
(en)
*
|
1999-02-24 |
2002-05-16 |
Danishefsky Samuel J. |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
AU2002211427A1
(en)
*
|
2000-10-05 |
2002-04-15 |
Whitehead Institute For Biomedical Research |
Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors
|
|
CA2424345A1
(en)
*
|
2000-10-16 |
2002-04-25 |
Neopharm, Inc. |
Liposomal formulation of mitoxantrone
|
|
US20050209310A1
(en)
*
|
2000-12-22 |
2005-09-22 |
Chaplin David J |
Methods for modulating tumor growth and metastasis
|
|
US7037906B1
(en)
*
|
2000-12-22 |
2006-05-02 |
Oxigene, Inc. |
Methods for modulating tumor growth and metastasis
|
|
BRPI0207961B8
(pt)
*
|
2001-03-14 |
2021-05-25 |
Bristol Myers Squibb Co |
uso de análogos de epotilona e capecitabina para fabricar medicamento para tratar tumores cancerosos sólidos e kit compreendendo os referidos compostos.
|
|
MXPA03010401A
(es)
*
|
2001-05-16 |
2004-03-09 |
Novartis Ag |
Combinacion que comprende n-[5-[4- (4-metil- piperazino-metil) -benzoilamido] -2-metilfenil] -4-(3-piridil)-2 -pirimidin-amina, y un agente quimioterapeutico.
|
|
NZ532418A
(en)
*
|
2001-10-25 |
2007-02-23 |
Novartis Ag |
Combinations comprising a selective cyclooxygenase-2 inhibitor and a microtubule interfering agent
|
|
GB0126879D0
(en)
*
|
2001-11-08 |
2002-01-02 |
Astrazeneca Ab |
Combination therapy
|
|
AU2002359412A1
(en)
*
|
2001-11-13 |
2003-05-26 |
Bristol-Myers Squibb Company |
Process for the preparation of 3,7-disubstituted-2,3,4,5- tetrahydro-1h-1,4-benzodiazepine compounds
|
|
TW200408407A
(en)
*
|
2001-11-30 |
2004-06-01 |
Dana Farber Cancer Inst Inc |
Methods and compositions for modulating the immune system and uses thereof
|
|
GEP20063806B
(en)
*
|
2001-12-20 |
2006-04-25 |
Bristol Myers Squibb Co |
Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability
|
|
US6998391B2
(en)
*
|
2002-02-07 |
2006-02-14 |
Supergen.Inc. |
Method for treating diseases associated with abnormal kinase activity
|
|
US20030147813A1
(en)
*
|
2002-02-07 |
2003-08-07 |
John Lyons |
Method for treating chronic myelogenous leukemia
|
|
MEP16308A
(en)
*
|
2002-05-17 |
2010-06-10 |
Aventis Pharma Sa |
Use of docetaxel/doxorubicin/cyclophosphamide in adjuvant therapy of breast and ovarian cancer
|
|
KR101086533B1
(ko)
*
|
2002-05-24 |
2011-11-23 |
쉐링 코포레이션 |
중화 사람 항-igfr 항체, 이를 제조하는 방법 및 이를 포함하는 조성물
|
|
US6627614B1
(en)
*
|
2002-06-05 |
2003-09-30 |
Super Gen, Inc. |
Sequential therapy comprising a 20(S)-camptothecin and an anthracycline
|
|
AU2003242646A1
(en)
*
|
2002-06-10 |
2003-12-22 |
Novartis Ag |
Combinations comprising epothilones and pharmaceutical uses thereof
|
|
RU2379032C9
(ru)
*
|
2002-06-10 |
2010-03-27 |
Новартис Аг |
Комбинации, включающие эпотилоны, и их фармацевтическое применение
|
|
US7649006B2
(en)
*
|
2002-08-23 |
2010-01-19 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
ES2281692T3
(es)
*
|
2002-08-23 |
2007-10-01 |
Sloan-Kettering Institute For Cancer Research |
Sintesis de epotilones, sus intermediarios, sus analogos y sus usos.
|
|
US6921769B2
(en)
|
2002-08-23 |
2005-07-26 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto and analogues thereof
|
|
US20040209930A1
(en)
*
|
2002-10-02 |
2004-10-21 |
Carboni Joan M. |
Synergistic methods and compositions for treating cancer
|
|
GB0223380D0
(en)
*
|
2002-10-09 |
2002-11-13 |
Astrazeneca Ab |
Combination therapy
|
|
US8613922B2
(en)
|
2003-04-24 |
2013-12-24 |
The University Of North Carolina At Chapel Hill |
Methods for inhibiting diabetic retinopathy with an antibody against integrin associated protein (IAP)
|
|
US20050043233A1
(en)
|
2003-04-29 |
2005-02-24 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis
|
|
WO2005000230A2
(en)
*
|
2003-06-05 |
2005-01-06 |
Charles Achkar |
Methods of treating hyperproliferative cell disorders
|
|
EP1493445A1
(en)
*
|
2003-07-04 |
2005-01-05 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Inhibition of stress-induced ligand-dependent EGFR activation
|
|
CA2536912C
(en)
*
|
2003-08-27 |
2015-03-31 |
Eyetech Pharmaceuticals, Inc. |
Combination therapy for the treatment of ocular neovascular disorders
|
|
CN1938428A
(zh)
|
2003-11-12 |
2007-03-28 |
先灵公司 |
多基因表达的质粒系统
|
|
WO2005046665A1
(en)
*
|
2003-11-13 |
2005-05-26 |
Warner-Lambert Company Llc |
Combination chemotherapy comprising a mek inhibitor and a erbb1/2 receptor inhibitor
|
|
AR046639A1
(es)
*
|
2003-11-21 |
2005-12-14 |
Schering Corp |
Combinaciones terapeuticas de anticuerpo anti- igfr1
|
|
US7612071B2
(en)
*
|
2004-03-12 |
2009-11-03 |
Syntrix Biosystems, Inc. |
Compositions and methods employing aminopterin
|
|
US20070293539A1
(en)
*
|
2004-03-18 |
2007-12-20 |
Lansbury Peter T |
Methods for the treatment of synucleinopathies
|
|
US20050272722A1
(en)
*
|
2004-03-18 |
2005-12-08 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies
|
|
EP1732549A4
(en)
*
|
2004-03-18 |
2009-11-11 |
Brigham & Womens Hospital |
METHOD FOR THE TREATMENT OF SYNUCLEINOPATHIES
|
|
WO2005089502A2
(en)
*
|
2004-03-18 |
2005-09-29 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies
|
|
US20060106060A1
(en)
*
|
2004-03-18 |
2006-05-18 |
The Brigham And Women's Hospital, Inc. |
Methods for the treatment of synucleinopathies (Lansbury)
|
|
WO2005089518A2
(en)
*
|
2004-03-18 |
2005-09-29 |
The Brigham And Women's Hospital, Inc. |
Uch-l1 expression and cancer therapy
|
|
KR20060130764A
(ko)
*
|
2004-03-23 |
2006-12-19 |
아스트라제네카 아베 |
병용 요법
|
|
GB0406446D0
(en)
*
|
2004-03-23 |
2004-04-28 |
Astrazeneca Ab |
Combination therapy
|
|
JP4699450B2
(ja)
|
2004-04-15 |
2011-06-08 |
ジェネンコー・インターナショナル・インク |
Cab分子、ceaを対象とするadept構築
|
|
US7449196B2
(en)
*
|
2004-07-09 |
2008-11-11 |
Robert Sabin |
Anti tumor compositions and methods of use
|
|
CN101014365B
(zh)
*
|
2004-07-16 |
2011-04-13 |
辉瑞产品公司 |
使用抗-igf-1r抗体联合治疗非血液的恶性肿瘤
|
|
GB0419071D0
(en)
|
2004-08-26 |
2004-09-29 |
Mgx Internat Ltd |
Display device
|
|
GB0424339D0
(en)
*
|
2004-11-03 |
2004-12-08 |
Astrazeneca Ab |
Combination therapy
|
|
TW200628156A
(en)
*
|
2004-11-04 |
2006-08-16 |
Bristol Myers Squibb Co |
Combination of a SRC kinase inhibitor and a BCR-ABL inhibitor for the treatment of proliferative diseases
|
|
JP2008521907A
(ja)
*
|
2004-12-03 |
2008-06-26 |
シェーリング コーポレイション |
抗igf1r治療について患者を予め選択するためのバイオマーカー
|
|
CA2594482C
(en)
*
|
2005-01-19 |
2013-10-01 |
Zeria Pharmaceutical Co., Ltd. |
Antitumor agent
|
|
CN113952338A
(zh)
*
|
2005-02-03 |
2022-01-21 |
综合医院公司 |
治疗吉非替尼耐药性癌症的方法
|
|
EP2634252B1
(en)
|
2005-02-11 |
2018-12-19 |
University of Southern California |
Method of expressing proteins with disulfide bridges
|
|
US20060194821A1
(en)
*
|
2005-02-18 |
2006-08-31 |
The Brigham And Women's Hospital, Inc. |
Compounds inhibiting the aggregation of superoxide dismutase-1
|
|
RU2276613C1
(ru)
*
|
2005-03-17 |
2006-05-20 |
Российская медицинская академия последипломного образования Министерства здравоохранения Российской Федерации (РМАПО МЗ РФ) |
Способ лечения злокачественных опухолей головки поджелудочной железы
|
|
US20060235006A1
(en)
*
|
2005-04-13 |
2006-10-19 |
Lee Francis Y |
Combinations, methods and compositions for treating cancer
|
|
JP4875064B2
(ja)
*
|
2005-04-15 |
2012-02-15 |
シェーリング コーポレイション |
癌を処置または予防するための方法および組成物
|
|
US8101728B2
(en)
*
|
2005-04-28 |
2012-01-24 |
Danisco Us Inc. |
TAB molecules
|
|
AR053272A1
(es)
*
|
2005-05-11 |
2007-04-25 |
Hoffmann La Roche |
Determinacion de responsivos a la quimioterapia
|
|
US20060286103A1
(en)
*
|
2005-06-15 |
2006-12-21 |
Parag Kolhe |
Stable antibody formulation
|
|
FR2887454B1
(fr)
*
|
2005-06-28 |
2009-06-05 |
Sanofi Aventis Sa |
Combinaisons antitumorales contenant des derives du taxane et des sigma ligands
|
|
CN103110948A
(zh)
|
2005-11-04 |
2013-05-22 |
惠氏公司 |
mTOR抑制剂、赫赛汀和/或HKI-272的抗肿瘤组合
|
|
US8546404B2
(en)
|
2005-12-13 |
2013-10-01 |
Merck Sharp & Dohme |
Compounds that are ERK inhibitors
|
|
JP2009528280A
(ja)
|
2006-02-16 |
2009-08-06 |
シェーリング コーポレイション |
Erkインヒビターとしてのピロリジン誘導体
|
|
US8044033B2
(en)
*
|
2006-03-02 |
2011-10-25 |
The Board Of Regents Of The University Of Texas System |
Fluorocytidine derivatives and COX-2 inhibitors for the treatment of cancer
|
|
WO2007130501A2
(en)
*
|
2006-05-01 |
2007-11-15 |
University Of Southern California |
Combination therapy for treatment of cancer
|
|
RU2325914C2
(ru)
*
|
2006-06-15 |
2008-06-10 |
Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) |
Способ лечения операбельного рака молочной железы
|
|
US20080081051A1
(en)
*
|
2006-09-28 |
2008-04-03 |
Robert Sabin |
Method of manufacturing anti-tumor and anti-viral compositions
|
|
US20080085881A1
(en)
*
|
2006-10-06 |
2008-04-10 |
Aimery De Gramont |
Stop-and-go oxaliplatin treatment regimens
|
|
WO2008065409A2
(en)
*
|
2006-12-01 |
2008-06-05 |
Betagenon Ab |
Combination for use in the treatment of cancer, comprising tamoxifen or an aromatase inhibitor
|
|
CN101657203B
(zh)
*
|
2007-03-02 |
2012-09-05 |
卧龙岗大学 |
抗癌药的组合物及递送方法
|
|
WO2008115478A2
(en)
*
|
2007-03-19 |
2008-09-25 |
University Of Medicine And Dentistry Of New Jersey |
Method of cancer detection and treatment
|
|
EP2190287B1
(en)
|
2007-09-10 |
2014-10-29 |
Curis, Inc. |
Tartrate salts or complexes of quinazoline based egfr inhibitors containing a zinc binding moiety
|
|
WO2009033204A1
(en)
*
|
2007-09-12 |
2009-03-19 |
University Of Wollongong |
Multi-component compositions and methods for delivery of anti-cancer agents
|
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
|
ES2402138T3
(es)
*
|
2007-12-28 |
2013-04-29 |
Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts |
Terapia contra el cáncer con un parvovirus combinado con quimioterapia
|
|
CN101969963A
(zh)
*
|
2008-01-28 |
2011-02-09 |
那野伽利阿株式会社 |
医药组合物或组合剂
|
|
SG188179A1
(en)
|
2008-02-21 |
2013-03-28 |
Merck Sharp & Dohme |
Compounds that are erk inhibitors
|
|
US8232402B2
(en)
*
|
2008-03-12 |
2012-07-31 |
Link Medicine Corporation |
Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
|
|
CA2725390C
(en)
*
|
2008-04-08 |
2014-09-23 |
Syndax Pharmaceuticals, Inc. |
Use of a hdac inhibitor and a her-2 inhibitor in the treatment of breast cancer
|
|
RU2365370C1
(ru)
*
|
2008-04-29 |
2009-08-27 |
Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН |
Способ лечения рака легкого
|
|
EP3135285B1
(en)
|
2008-06-17 |
2018-08-15 |
Wyeth LLC |
Antineoplastic combinations containing hki-272 and vinorelbine
|
|
US8802394B2
(en)
|
2008-11-13 |
2014-08-12 |
Radu O. Minea |
Method of expressing proteins with disulfide bridges with enhanced yields and activity
|
|
US8343996B2
(en)
*
|
2008-11-13 |
2013-01-01 |
Astrazeneca Ab |
Azaquinolinone derivatives and uses thereof
|
|
US20100331363A1
(en)
*
|
2008-11-13 |
2010-12-30 |
Link Medicine Corporation |
Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
|
|
US20110060005A1
(en)
*
|
2008-11-13 |
2011-03-10 |
Link Medicine Corporation |
Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
|
|
AU2009319050B2
(en)
*
|
2008-11-28 |
2014-01-30 |
Novartis Ag |
Pharmaceutical combinations comprising a pyrido [4, 3-d] pyrimidine derived Hsp90-inhibitor and a HER2 inhibitor
|
|
US20120189641A1
(en)
|
2009-02-25 |
2012-07-26 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
US8642834B2
(en)
|
2009-02-27 |
2014-02-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
EP2401613A2
(en)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
US20110300150A1
(en)
|
2010-05-18 |
2011-12-08 |
Scott Eliasof |
Compositions and methods for treatment of autoimmune and other disease
|
|
DK2500036T3
(da)
*
|
2011-03-18 |
2014-08-04 |
Metheresis Translational Res Sa |
MET-hæmmere til øgning af virkningen af radioterapi
|
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
CN103374000B
(zh)
*
|
2012-04-13 |
2015-11-11 |
中国科学院广州生物医药与健康研究院 |
嘧啶并二氮杂卓类化合物及其药用组合物和应用
|
|
FI4374873T3
(fi)
|
2013-07-12 |
2025-12-04 |
Astellas Us Llc |
Aine käytettäväksi silmäsairauksien hoidossa tai ehkäisyssä
|
|
CN107043456B
(zh)
*
|
2017-04-19 |
2019-05-17 |
川北医学院 |
对氧环己酮与l-苯丙氨酸氮芥共聚物及其应用
|
|
FI3642344T3
(fi)
|
2017-06-21 |
2025-03-13 |
Univ North Carolina Chapel Hill |
Menetelmiä ja koostumuksia syöpäsoluihin kohdentuvaa kimeeristä antigeenireseptoria varten
|
|
WO2019240935A1
(en)
|
2018-06-13 |
2019-12-19 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for chimeric antigen receptor targeting cancer cells
|
|
US11068254B1
(en)
|
2020-06-10 |
2021-07-20 |
Cigna Intellectual Property, Inc. |
Systems and methods for generating and managing domain-based technology architecture
|
|
JP2024521216A
(ja)
*
|
2021-06-03 |
2024-05-28 |
ユニバーシティ・オブ・シンシナティ |
がんの化学増感剤としてのbzd-1
|
|
CN115814076A
(zh)
*
|
2021-07-01 |
2023-03-21 |
江苏先声药业有限公司 |
抗人vegf抗体与化药联用在制备治疗卵巢癌的药物中的应用
|
|
US11879010B2
(en)
|
2021-09-30 |
2024-01-23 |
The Charlotte Mecklenburg Hospital Authority |
Methods and compositions for pretargeted immunotherapy
|
|
CN114712377B
(zh)
*
|
2022-04-26 |
2023-08-15 |
江苏师范大学 |
断血流皂苷a在制造药物中的用途
|