AR012054A1 - A PHARMACEUTICAL COMPOSITIONS - Google Patents
A PHARMACEUTICAL COMPOSITIONSInfo
- Publication number
- AR012054A1 AR012054A1 ARP980101125A ARP980101125A AR012054A1 AR 012054 A1 AR012054 A1 AR 012054A1 AR P980101125 A ARP980101125 A AR P980101125A AR P980101125 A ARP980101125 A AR P980101125A AR 012054 A1 AR012054 A1 AR 012054A1
- Authority
- AR
- Argentina
- Prior art keywords
- hydrophilic
- component
- mixture
- fatty acid
- pharmaceutical compositions
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 3
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 2
- 108010036949 Cyclosporine Proteins 0.000 abstract 2
- 229960001265 ciclosporin Drugs 0.000 abstract 2
- 229930182912 cyclosporin Natural products 0.000 abstract 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 abstract 1
- 239000007901 soft capsule Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invencion se refiere a una preparacion de cápsula blandaque contiene ciclosporina, la cual comprende una composicion que contieneciclosporina como ingrediente activo; un componente hidrofílico de glicol de polietileno, o un componente no hidrofílico de carbonato de propileno o sumezcla, uno o una mezcla de dos o más seleccionados a partir del grupo que consiste en un compuesto esterificado de ácido graso de cadena mediana, ymonoglicérido de ácido graso como un componentede aceite; y un tensoactivo que tiene un valor HLB (Equilibrio Hidrofílico-Lipofílico) de 8 a 17.The present invention relates to a soft capsule preparation containing cyclosporin, which comprises a composition containing cyclosporin as an active ingredient; a hydrophilic component of polyethylene glycol, or a non-hydrophilic component of propylene carbonate or its mixture, one or a mixture of two or more selected from the group consisting of an esterified compound of medium chain fatty acid, and fatty acid monoglyceride as a component of oil; and a surfactant that has an HLB (Hydrophilic-Lipophilic Balance) value of 8 to 17.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019970008750A KR19980073479A (en) | 1997-03-14 | 1997-03-14 | Cyclosporine-containing soft capsules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR012054A1 true AR012054A1 (en) | 2000-09-27 |
Family
ID=19499792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980101125A AR012054A1 (en) | 1997-03-14 | 1998-03-13 | A PHARMACEUTICAL COMPOSITIONS |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0969857A1 (en) |
| JP (1) | JP3748573B2 (en) |
| KR (2) | KR19980073479A (en) |
| CN (1) | CN1161150C (en) |
| AR (1) | AR012054A1 (en) |
| AU (1) | AU741923B2 (en) |
| BR (1) | BR9808324A (en) |
| CA (1) | CA2283901A1 (en) |
| CO (1) | CO4940404A1 (en) |
| CZ (1) | CZ324399A3 (en) |
| DE (1) | DE19882184T1 (en) |
| GB (1) | GB2337703A (en) |
| HU (1) | HUP0001515A3 (en) |
| ID (1) | ID23531A (en) |
| IL (1) | IL131703A0 (en) |
| MY (1) | MY118614A (en) |
| NO (1) | NO994436L (en) |
| PE (1) | PE59499A1 (en) |
| PL (1) | PL335729A1 (en) |
| RU (1) | RU2185188C2 (en) |
| SK (1) | SK123299A3 (en) |
| TR (1) | TR199902229T2 (en) |
| WO (1) | WO1998041225A1 (en) |
| ZA (1) | ZA982117B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2380674B (en) * | 1998-03-06 | 2003-05-28 | Novartis Ag | Emulsion preconcentrates containing cyclosporin or a macrolide |
| US7203158B2 (en) * | 2000-12-06 | 2007-04-10 | Matsushita Electric Industrial Co., Ltd. | OFDM signal transmission system, portable terminal, and e-commerce system |
| GB0526419D0 (en) * | 2005-12-23 | 2006-02-08 | Cyclacel Ltd | Formulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5603951A (en) * | 1994-11-09 | 1997-02-18 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin-containing soft capsule compositions |
| HU215966B (en) * | 1994-11-21 | 1999-07-28 | BIOGAL Gyógyszergyár Rt. | Oral multiple emulsion-preconcentrate containing cyclosporin |
| KR0167613B1 (en) * | 1994-12-28 | 1999-01-15 | 한스 루돌프 하우스, 니콜 케르커 | Cyclosporine-containing soft capsule composition |
| US6465627B2 (en) * | 1995-07-28 | 2002-10-15 | The Regents Of The University Of California | DAX-1 protein, methods for production and use thereof |
| NZ280689A (en) * | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
| KR0183449B1 (en) * | 1996-06-19 | 1999-05-01 | 한스 루돌프 하우스, 니콜 케르커 | Cyclosporine-containing soft capsules |
| CZ292378B6 (en) * | 1996-06-19 | 2003-09-17 | Novartis Ag | Formulation containing cyclosporine and process of its preparation |
-
1997
- 1997-03-14 KR KR1019970008750A patent/KR19980073479A/en not_active Ceased
-
1998
- 1998-03-12 GB GB9921495A patent/GB2337703A/en not_active Withdrawn
- 1998-03-12 PE PE1998000174A patent/PE59499A1/en not_active Application Discontinuation
- 1998-03-12 DE DE19882184T patent/DE19882184T1/en not_active Withdrawn
- 1998-03-12 TR TR1999/02229T patent/TR199902229T2/en unknown
- 1998-03-12 WO PCT/EP1998/001432 patent/WO1998041225A1/en not_active Ceased
- 1998-03-12 SK SK1232-99A patent/SK123299A3/en unknown
- 1998-03-12 MY MYPI98001086A patent/MY118614A/en unknown
- 1998-03-12 IL IL13170398A patent/IL131703A0/en unknown
- 1998-03-12 AU AU67293/98A patent/AU741923B2/en not_active Ceased
- 1998-03-12 CN CNB988033569A patent/CN1161150C/en not_active Expired - Fee Related
- 1998-03-12 ZA ZA982117A patent/ZA982117B/en unknown
- 1998-03-12 CA CA002283901A patent/CA2283901A1/en not_active Abandoned
- 1998-03-12 ID IDW990997A patent/ID23531A/en unknown
- 1998-03-12 CZ CZ993243A patent/CZ324399A3/en unknown
- 1998-03-12 KR KR1019997008022A patent/KR20000075940A/en not_active Ceased
- 1998-03-12 BR BR9808324-4A patent/BR9808324A/en not_active Application Discontinuation
- 1998-03-12 RU RU99121398/14A patent/RU2185188C2/en not_active IP Right Cessation
- 1998-03-12 PL PL98335729A patent/PL335729A1/en unknown
- 1998-03-12 JP JP54011298A patent/JP3748573B2/en not_active Expired - Fee Related
- 1998-03-12 EP EP98912470A patent/EP0969857A1/en not_active Withdrawn
- 1998-03-12 HU HU0001515A patent/HUP0001515A3/en unknown
- 1998-03-13 AR ARP980101125A patent/AR012054A1/en not_active Application Discontinuation
- 1998-03-13 CO CO98014254A patent/CO4940404A1/en unknown
-
1999
- 1999-09-13 NO NO994436A patent/NO994436L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1250378A (en) | 2000-04-12 |
| CN1161150C (en) | 2004-08-11 |
| CZ324399A3 (en) | 1999-12-15 |
| RU2185188C2 (en) | 2002-07-20 |
| DE19882184T1 (en) | 2000-02-10 |
| HUP0001515A3 (en) | 2000-10-30 |
| CA2283901A1 (en) | 1998-09-24 |
| KR20000075940A (en) | 2000-12-26 |
| BR9808324A (en) | 2000-05-16 |
| AU6729398A (en) | 1998-10-12 |
| GB2337703A (en) | 1999-12-01 |
| IL131703A0 (en) | 2001-03-19 |
| NO994436D0 (en) | 1999-09-13 |
| JP2000514831A (en) | 2000-11-07 |
| ZA982117B (en) | 1998-09-14 |
| WO1998041225A1 (en) | 1998-09-24 |
| PL335729A1 (en) | 2000-05-08 |
| GB9921495D0 (en) | 1999-11-17 |
| ID23531A (en) | 2000-04-27 |
| PE59499A1 (en) | 1999-07-05 |
| TR199902229T2 (en) | 1999-12-21 |
| JP3748573B2 (en) | 2006-02-22 |
| NO994436L (en) | 1999-09-13 |
| SK123299A3 (en) | 2000-02-14 |
| HUP0001515A2 (en) | 2000-09-28 |
| KR19980073479A (en) | 1998-11-05 |
| MY118614A (en) | 2004-12-31 |
| EP0969857A1 (en) | 2000-01-12 |
| AU741923B2 (en) | 2001-12-13 |
| CO4940404A1 (en) | 2000-07-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2175217T3 (en) | PREPARED SOFT CAPSULES CONTAINING CYCLOSPORINE. | |
| LV11884A (en) | High bioavailability of ciclosporina oralas | |
| CO4940469A1 (en) | ORAL COMPOSITION OF IMPROVED STABILITY INCLUDING A DERIVATIVE OF INDOLINONE AND A MIXTURE OF GLYCERIDES OR POLYETHYLENE GLYCOL ESTERS | |
| RU2007120070A (en) | PHARMACEUTICAL AND VETERINARY PASTE COMPOSITIONS | |
| HK40583A (en) | Nifedipine-containing solid preparation composition | |
| ES2098672T3 (en) | STABILIZED PHARMACEUTICAL COMPOSITIONS CONTAINING D2 AND D3 VITAMIN DERIVATIVES. | |
| BR9706804A (en) | Soft capsule preparations containing cyclosporine. | |
| BR0012303A (en) | Fat composition | |
| EP1566166A4 (en) | Base for oral composition and oral composition | |
| PT734253E (en) | FORMULATION OF BIPHASIC CAPSULES | |
| WO2002019972A3 (en) | Stabilized ascorbic acid solutions | |
| KR950010875A (en) | External skin preparation | |
| UY26303A1 (en) | PHARMACEUTICAL COMPOSITIONS FOR ORAL AND TOPICAL ADMINISTRATION | |
| BR0111678A (en) | Medicinal compositions containing propenone derivatives | |
| WO2001093816A3 (en) | Stabilized compositions containing oxygen-labile active agents | |
| DK0657164T3 (en) | Pharmaceutical compositions containing staurosporine derivatives and a polyalkylene glycol glyceride | |
| AR012054A1 (en) | A PHARMACEUTICAL COMPOSITIONS | |
| RU98105629A (en) | DRUGS CONTAINING CYCLOSPORIN, IN THE FORM OF SOFT COATED CAPSULES | |
| ES2572133T3 (en) | Pharmaceutical compositions comprising a camptothecin derivative | |
| ES2150404T1 (en) | PHARMACEUTICAL COMPOSITIONS OF TIZOXANIDE AND NITOZOXANIDE. | |
| ECSP982444A (en) | PHARMACEUTICAL COMPOSITIONS | |
| PT1255535E (en) | CONTROLLED LIBERATION PHARMACEUTICAL COMPOSITION CONTAINING TRAMADOL CHLORIDRATE | |
| ECSP972157A (en) | SOFT CAPSULE PREPARATIONS CONTAINING CYCLOSPORIN | |
| RU99121398A (en) | PHARMACEUTICAL COMPOSITIONS | |
| TH37488A (en) | Pharmaceutical mixtures |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |