GB2380674B - Emulsion preconcentrates containing cyclosporin or a macrolide - Google Patents

Emulsion preconcentrates containing cyclosporin or a macrolide

Info

Publication number: GB2380674B
Authority: GB; United Kingdom
Prior art keywords: macrolide; containing cyclosporin; emulsion preconcentrates; preconcentrates containing; emulsion
Prior art date: 1998-03-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Revoked

Application number

GB0229289A

Other versions

GB2380674A (en

GB0229289D0 (en

Inventor

Michael Ambuehl

Barbara Lueckel

Friedrich Richter

Barbara Haeberlin

Armin Meinzer

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

Novartis AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-06

Filing date

1999-03-04

Publication date

2003-05-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27447881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2380674(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-03-06 Priority claimed from GBGB9804742.6A external-priority patent/GB9804742D0/en

1998-03-10 Priority claimed from GBGB9805104.8A external-priority patent/GB9805104D0/en

1998-03-11 Priority claimed from GBGB9805199.8A external-priority patent/GB9805199D0/en

1999-03-04 Application filed by Novartis AG filed Critical Novartis AG

1999-03-04 Priority claimed from GB0021495A external-priority patent/GB2350791B/en

2003-01-22 Publication of GB0229289D0 publication Critical patent/GB0229289D0/en

2003-04-16 Publication of GB2380674A publication Critical patent/GB2380674A/en

2003-05-28 Application granted granted Critical

2003-05-28 Publication of GB2380674B publication Critical patent/GB2380674B/en

2019-03-04 Anticipated expiration legal-status Critical

Status Revoked legal-status Critical Current

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
229930105110 Cyclosporin A Natural products 0.000 title 1
108010036949 Cyclosporine Proteins 0.000 title 1
229960001265 ciclosporin Drugs 0.000 title 1
229930182912 cyclosporin Natural products 0.000 title 1
239000000839 emulsion Substances 0.000 title 1
239000003120 macrolide antibiotic agent Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Immunology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dispersion Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Transplantation (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)

GB0229289A 1998-03-06 1999-03-04 Emulsion preconcentrates containing cyclosporin or a macrolide Revoked GB2380674B (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9804742.6A GB9804742D0 (en)	1998-03-06	1998-03-06	Organic compounds
GBGB9805104.8A GB9805104D0 (en)	1998-03-10	1998-03-10	Organic compounds
GBGB9805199.8A GB9805199D0 (en)	1998-03-11	1998-03-11	Organic compounds
GB0021495A GB2350791B (en)	1998-03-06	1999-03-04	Emulsion preconcentrates containing cyclosporin or a macrolide

Publications (3)

Publication Number	Publication Date
GB0229289D0 GB0229289D0 (en)	2003-01-22
GB2380674A GB2380674A (en)	2003-04-16
GB2380674B true GB2380674B (en)	2003-05-28

Family

ID=27447881

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
GB0229289A Revoked GB2380674B (en)	1998-03-06	1999-03-04	Emulsion preconcentrates containing cyclosporin or a macrolide
GB0229284A Expired - Fee Related GB2380673B (en)	1998-03-06	1999-03-04	Emulsion preconcentrates containing cyclosporin or a macrolide

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
GB0229284A Expired - Fee Related GB2380673B (en)	1998-03-06	1999-03-04	Emulsion preconcentrates containing cyclosporin or a macrolide

Country Status (1)

Country	Link
GB (2)	GB2380674B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8535716B2 (en)	2004-04-01	2013-09-17	Tsrl, Inc.	Methods and composition of extended delivery of water insoluble drugs
EP2204167A1 (en) *	2009-01-05	2010-07-07	Azad Pharma AG	Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules
JP5717034B2 (en) *	2012-08-27	2015-05-13	丸和バイオケミカル株式会社	Soil nematode control agent containing macrolide compounds

Citations (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2222770A (en) *	1988-09-16	1990-03-21	Sandoz Ltd	Cyclosporin emulsion compositions
GB2278780A (en) *	1993-05-27	1994-12-14	Sandoz Ltd	Macrolide antibiotic emulsions
WO1996013273A1 (en) *	1994-10-26	1996-05-09	Novartis Ag	Pharmaceutical compositions
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
EP0793966A1 (en) *	1996-03-05	1997-09-10	Hanmi Pharm. Co. Ltd	Cyclosporin-containing topical pharmaceutical composition
WO1998010747A1 (en) *	1996-09-12	1998-03-19	Galena As	Immunomodulatory formulation
WO1998041225A1 (en) *	1997-03-14	1998-09-24	Novartis Ag	Pharmaceutical compositions
WO1999000002A2 (en) *	1997-12-05	1999-01-07	Chong Kun Dang Corp.	Cyclosporin-containing microemulsion preconcentrate composition
EP1142568A1 (en) *	1992-09-25	2001-10-10	Novartis AG	Pharmaceutical compositions containing cyclosporins

1999
- 1999-03-04 GB GB0229289A patent/GB2380674B/en not_active Revoked
- 1999-03-04 GB GB0229284A patent/GB2380673B/en not_active Expired - Fee Related

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639724A (en) *	1984-07-24	1997-06-17	Sandoz Ltd.	Cyclosporin galenic forms
GB2222770A (en) *	1988-09-16	1990-03-21	Sandoz Ltd	Cyclosporin emulsion compositions
EP1142568A1 (en) *	1992-09-25	2001-10-10	Novartis AG	Pharmaceutical compositions containing cyclosporins
GB2278780A (en) *	1993-05-27	1994-12-14	Sandoz Ltd	Macrolide antibiotic emulsions
WO1996013273A1 (en) *	1994-10-26	1996-05-09	Novartis Ag	Pharmaceutical compositions
EP0793966A1 (en) *	1996-03-05	1997-09-10	Hanmi Pharm. Co. Ltd	Cyclosporin-containing topical pharmaceutical composition
WO1998010747A1 (en) *	1996-09-12	1998-03-19	Galena As	Immunomodulatory formulation
WO1998041225A1 (en) *	1997-03-14	1998-09-24	Novartis Ag	Pharmaceutical compositions
WO1999000002A2 (en) *	1997-12-05	1999-01-07	Chong Kun Dang Corp.	Cyclosporin-containing microemulsion preconcentrate composition

Also Published As

Publication number	Publication date
GB2380673B (en)	2003-05-28
GB0229284D0 (en)	2003-01-22
GB2380673A (en)	2003-04-16
GB2380674A (en)	2003-04-16
GB0229289D0 (en)	2003-01-22

Publication	Publication Date	Title
GB2350791B (en)	2003-04-02	Emulsion preconcentrates containing cyclosporin or a macrolide
HUP0001330A3 (en)	2000-09-28	3'-n-oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
EP1091212A4 (en)	2003-01-15	Acceleration sensor
SG53038A1 (en)	1998-09-28	Acceleration sensor
GB9800042D0 (en)	1998-03-04	Marine devices
GB0111938D0 (en)	2001-07-04	A buoyancy device
GB2380674B (en)	2003-05-28	Emulsion preconcentrates containing cyclosporin or a macrolide
IL139501A0 (en)	2001-11-25	Microemulsion preconcentrates containing a piperidin substance p antagonist
GB2329369B (en)	2000-01-19	Marine sensing surveying
SI1059913T1 (en)	2005-02-28	Emulsion preconcentrates containing cyclosporin or a macrolide
HK1056310A1 (en)	2004-02-13	Emulsion preconcentrates containing cyclosporin or a macrolide
HK1056309B (en)	2005-03-18	Emulsion preconcentrates containing cyclosporin or a macrolide
HK1033277B (en)	2003-10-31	Emulsion preconcentrates containing cyclosporin or a macrolide
HK1056310B (en)	2005-05-27	Emulsion preconcentrates containing cyclosporin or a macrolide
GB2315216B (en)	1998-10-14	Microemulsion preconcentrates comprising FK506 or 33-epi-chloro-33-desoxy-ascomycin
GB2338008B (en)	2002-08-28	A retaining device
TW397234U (en)	2000-07-01	A map capable of distinguishing a direction
PL342742A1 (en)	2001-07-02	Emulsion-type pre-concentrates containing cyclosporin or macrolyde
DE19882184T1 (en)	2000-02-10	Preparation containing cyclosporin
GB2308545B (en)	1999-06-02	Pharmaceutical microemulsion preconcentrates
SI1082119T1 (en)	2004-06-30	Microemulsion preconcentrates containing a piperidine substance p antagonist
AU139241S (en)	1999-12-15	A console
AU139648S (en)	2000-02-03	A console
GB9817874D0 (en)	1998-10-14	Navigation plotter
AU134353S (en)	1998-07-13	A grommet

Legal Events

Date	Code	Title	Description
2005-05-27	REG	Reference to a national code	Ref country code: HK Ref legal event code: GR Ref document number: 1056310 Country of ref document: HK
2006-07-12	7276	Counter claim for revocation lodged in the pat. court (section 72)
2006-12-20	772B	Case decided by the comptroller ** patent revoked (sect. 72/1977)	Free format text: PATENT REVOKED

Date

Code

Title

Description

2005-05-27

REG

Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1056310

Country of ref document: HK

2006-07-12

7276

Counter claim for revocation lodged in the pat. court (section 72)

2006-12-20

772B

Case decided by the comptroller ** patent revoked (sect. 72/1977)

Free format text: PATENT REVOKED