BR9808324A - Pharmaceutical compositions - Google Patents
Pharmaceutical compositionsInfo
- Publication number
- BR9808324A BR9808324A BR9808324-4A BR9808324A BR9808324A BR 9808324 A BR9808324 A BR 9808324A BR 9808324 A BR9808324 A BR 9808324A BR 9808324 A BR9808324 A BR 9808324A
- Authority
- BR
- Brazil
- Prior art keywords
- fatty acid
- hydrophilic
- pharmaceutical compositions
- mixture
- component
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 3
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 2
- 108010036949 Cyclosporine Proteins 0.000 abstract 2
- 229960001265 ciclosporin Drugs 0.000 abstract 2
- 229930182912 cyclosporin Natural products 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 239000002202 Polyethylene glycol Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 150000004667 medium chain fatty acids Chemical class 0.000 abstract 1
- -1 monoglyceride fatty acid Chemical class 0.000 abstract 1
- 229920001223 polyethylene glycol Polymers 0.000 abstract 1
- 150000003138 primary alcohols Chemical class 0.000 abstract 1
- RUOJZAUFBMNUDX-UHFFFAOYSA-N propylene carbonate Chemical compound CC1COC(=O)O1 RUOJZAUFBMNUDX-UHFFFAOYSA-N 0.000 abstract 1
- 239000007901 soft capsule Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçõES FARMECêUTICAS".<D> A presente invenção refere-se a uma preparação de cápsula macia contendo ciclosporina que compreende uma composição contendo ciclosporina como um ingrediente ativo; um componente hidrofílico polietileno glicol ou um componente não-hidrofílico carbonato de propileno ou sua mistura, um ou uma mistura de dois ou mais selecionados do grupo consistindo em um composto esterificado de ácido graxo e álcool primário, triglicerídeo de ácido graxo de cadeia média e monoglicerídeo de ácido graxo como um componente óleo; e um tensoatico tendo um valor HLB ( balanço hidrofílico lipofílico) de 8 a 17.Invention Patent: <B> "PHARMACEUTICAL COMPOSITIONS". <D> The present invention relates to a soft capsule preparation containing cyclosporine comprising a composition containing cyclosporine as an active ingredient; a hydrophilic polyethylene glycol component or a non-hydrophilic propylene carbonate component or mixture thereof, one or a mixture of two or more selected from the group consisting of an esterified compound of fatty acid and primary alcohol, medium chain fatty acid triglyceride and monoglyceride fatty acid as an oil component; and a surfactant having an HLB (lipophilic hydrophilic balance) value of 8 to 17.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019970008750A KR19980073479A (en) | 1997-03-14 | 1997-03-14 | Cyclosporine-containing soft capsules |
| PCT/EP1998/001432 WO1998041225A1 (en) | 1997-03-14 | 1998-03-12 | Pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9808324A true BR9808324A (en) | 2000-05-16 |
Family
ID=19499792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9808324-4A BR9808324A (en) | 1997-03-14 | 1998-03-12 | Pharmaceutical compositions |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0969857A1 (en) |
| JP (1) | JP3748573B2 (en) |
| KR (2) | KR19980073479A (en) |
| CN (1) | CN1161150C (en) |
| AR (1) | AR012054A1 (en) |
| AU (1) | AU741923B2 (en) |
| BR (1) | BR9808324A (en) |
| CA (1) | CA2283901A1 (en) |
| CO (1) | CO4940404A1 (en) |
| CZ (1) | CZ324399A3 (en) |
| DE (1) | DE19882184T1 (en) |
| GB (1) | GB2337703A (en) |
| HU (1) | HUP0001515A3 (en) |
| ID (1) | ID23531A (en) |
| IL (1) | IL131703A0 (en) |
| MY (1) | MY118614A (en) |
| NO (1) | NO994436D0 (en) |
| PE (1) | PE59499A1 (en) |
| PL (1) | PL335729A1 (en) |
| RU (1) | RU2185188C2 (en) |
| SK (1) | SK123299A3 (en) |
| TR (1) | TR199902229T2 (en) |
| WO (1) | WO1998041225A1 (en) |
| ZA (1) | ZA982117B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2380673B (en) * | 1998-03-06 | 2003-05-28 | Novartis Ag | Emulsion preconcentrates containing cyclosporin or a macrolide |
| US7203158B2 (en) * | 2000-12-06 | 2007-04-10 | Matsushita Electric Industrial Co., Ltd. | OFDM signal transmission system, portable terminal, and e-commerce system |
| GB0526419D0 (en) * | 2005-12-23 | 2006-02-08 | Cyclacel Ltd | Formulation |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5603951A (en) * | 1994-11-09 | 1997-02-18 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin-containing soft capsule compositions |
| HU215966B (en) * | 1994-11-21 | 1999-07-28 | BIOGAL Gyógyszergyár Rt. | Oral multiple emulsion-preconcentrate containing cyclosporin |
| KR0167613B1 (en) * | 1994-12-28 | 1999-01-15 | 한스 루돌프 하우스, 니콜 케르커 | Cyclosporine-containing soft capsule composition |
| WO1997004810A1 (en) * | 1995-07-28 | 1997-02-13 | The Regents Of The University Of California | Dax-1 protein, methods for production and use thereof |
| NZ280689A (en) * | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
| CZ292378B6 (en) * | 1996-06-19 | 2003-09-17 | Novartis Ag | Formulation containing cyclosporine and process of its preparation |
| KR0183449B1 (en) * | 1996-06-19 | 1999-05-01 | 한스 루돌프 하우스, 니콜 케르커 | Cyclosporine-containing soft capsules |
-
1997
- 1997-03-14 KR KR1019970008750A patent/KR19980073479A/en not_active Ceased
-
1998
- 1998-03-12 MY MYPI98001086A patent/MY118614A/en unknown
- 1998-03-12 DE DE19882184T patent/DE19882184T1/en not_active Withdrawn
- 1998-03-12 CA CA002283901A patent/CA2283901A1/en not_active Abandoned
- 1998-03-12 RU RU99121398/14A patent/RU2185188C2/en not_active IP Right Cessation
- 1998-03-12 TR TR1999/02229T patent/TR199902229T2/en unknown
- 1998-03-12 KR KR1019997008022A patent/KR20000075940A/en not_active Ceased
- 1998-03-12 SK SK1232-99A patent/SK123299A3/en unknown
- 1998-03-12 WO PCT/EP1998/001432 patent/WO1998041225A1/en not_active Ceased
- 1998-03-12 AU AU67293/98A patent/AU741923B2/en not_active Ceased
- 1998-03-12 GB GB9921495A patent/GB2337703A/en not_active Withdrawn
- 1998-03-12 BR BR9808324-4A patent/BR9808324A/en not_active Application Discontinuation
- 1998-03-12 ZA ZA982117A patent/ZA982117B/en unknown
- 1998-03-12 PL PL98335729A patent/PL335729A1/en unknown
- 1998-03-12 EP EP98912470A patent/EP0969857A1/en not_active Withdrawn
- 1998-03-12 IL IL13170398A patent/IL131703A0/en unknown
- 1998-03-12 HU HU0001515A patent/HUP0001515A3/en unknown
- 1998-03-12 JP JP54011298A patent/JP3748573B2/en not_active Expired - Fee Related
- 1998-03-12 PE PE1998000174A patent/PE59499A1/en not_active Application Discontinuation
- 1998-03-12 CZ CZ993243A patent/CZ324399A3/en unknown
- 1998-03-12 ID IDW990997A patent/ID23531A/en unknown
- 1998-03-12 CN CNB988033569A patent/CN1161150C/en not_active Expired - Fee Related
- 1998-03-13 CO CO98014254A patent/CO4940404A1/en unknown
- 1998-03-13 AR ARP980101125A patent/AR012054A1/en not_active Application Discontinuation
-
1999
- 1999-09-13 NO NO994436A patent/NO994436D0/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR19980073479A (en) | 1998-11-05 |
| JP3748573B2 (en) | 2006-02-22 |
| SK123299A3 (en) | 2000-02-14 |
| IL131703A0 (en) | 2001-03-19 |
| PE59499A1 (en) | 1999-07-05 |
| DE19882184T1 (en) | 2000-02-10 |
| CN1161150C (en) | 2004-08-11 |
| CN1250378A (en) | 2000-04-12 |
| HUP0001515A2 (en) | 2000-09-28 |
| TR199902229T2 (en) | 1999-12-21 |
| EP0969857A1 (en) | 2000-01-12 |
| PL335729A1 (en) | 2000-05-08 |
| AR012054A1 (en) | 2000-09-27 |
| RU2185188C2 (en) | 2002-07-20 |
| NO994436L (en) | 1999-09-13 |
| ID23531A (en) | 2000-04-27 |
| AU6729398A (en) | 1998-10-12 |
| WO1998041225A1 (en) | 1998-09-24 |
| CO4940404A1 (en) | 2000-07-24 |
| GB2337703A (en) | 1999-12-01 |
| HUP0001515A3 (en) | 2000-10-30 |
| GB9921495D0 (en) | 1999-11-17 |
| CA2283901A1 (en) | 1998-09-24 |
| KR20000075940A (en) | 2000-12-26 |
| ZA982117B (en) | 1998-09-14 |
| JP2000514831A (en) | 2000-11-07 |
| CZ324399A3 (en) | 1999-12-15 |
| MY118614A (en) | 2004-12-31 |
| NO994436D0 (en) | 1999-09-13 |
| AU741923B2 (en) | 2001-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR9706804A (en) | Soft capsule preparations containing cyclosporine. | |
| ES2175217T3 (en) | PREPARED SOFT CAPSULES CONTAINING CYCLOSPORINE. | |
| BR9807528A (en) | Oil-free pharmaceutical compositions containing cyclosporine a | |
| BR9811058A (en) | Self-emulsifying formulation for lipophilic compounds | |
| BR9810866A (en) | Pharmaceutical composition in a self-emulsifying formulation for lipophilic compounds | |
| ATE152613T1 (en) | COMPOSITION WHICH FORMES A MICROEMULSION UPON PERORAL ADMINISTRATION | |
| BR9611802A (en) | Pharmaceutical compositions | |
| BR0012303A (en) | Fat composition | |
| DE69939335D1 (en) | DISPERSIBLE CONCENTRATE FOR THE ADMINISTRATION OF CYCLOSPORIN | |
| BR0013385A (en) | Pharmaceutical compositions for oral and topical administration | |
| KR900012612A (en) | Pharmaceutical composition | |
| TNSN00145A1 (en) | STREPTOGRAMIN DERIVATIVES, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM | |
| RU98105629A (en) | DRUGS CONTAINING CYCLOSPORIN, IN THE FORM OF SOFT COATED CAPSULES | |
| BR9808324A (en) | Pharmaceutical compositions | |
| EE05231B1 (en) | Tramadol Hydrochloride Containing Controlled Release Pharmaceutical Composition and Method for its Preparation | |
| ECSP982444A (en) | PHARMACEUTICAL COMPOSITIONS | |
| RU99121398A (en) | PHARMACEUTICAL COMPOSITIONS | |
| KR890011594A (en) | Pharmaceutical composition of 4-aroylimidazol-2-one | |
| TH37488A (en) | Pharmaceutical mixtures | |
| ECSP972157A (en) | SOFT CAPSULE PREPARATIONS CONTAINING CYCLOSPORIN | |
| KR960033456A (en) | Antistress Pharmaceutical Composition | |
| KR950703333A (en) | Pharmaceutical Compositions Containing Nonionic Surfactants | |
| KR920019344A (en) | Prevention and treatment composition of liver disease using α-linolenic acid | |
| KR950005312A (en) | Pharmaceutical composition for treating liver disease and improving liver function | |
| KR950016750A (en) | Novel enteric omeprazole soft capsules and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |