AR015294A1 - Benzotiofenos, benzofuranos e indoles, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento - Google Patents
Benzotiofenos, benzofuranos e indoles, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamentoInfo
- Publication number
- AR015294A1 AR015294A1 ARP990102229A ARP990102229A AR015294A1 AR 015294 A1 AR015294 A1 AR 015294A1 AR P990102229 A ARP990102229 A AR P990102229A AR P990102229 A ARP990102229 A AR P990102229A AR 015294 A1 AR015294 A1 AR 015294A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- hydrogen
- aralkyl
- aryl
- hydroxyalkyl
- Prior art date
Links
- 150000002475 indoles Chemical class 0.000 title abstract 2
- MPNFMCAOBNNFJF-UHFFFAOYSA-N 2,3-diphenyl-1-benzofuran Chemical compound C1=CC=CC=C1C1=C(C=2C=CC=CC=2)C2=CC=CC=C2O1 MPNFMCAOBNNFJF-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 11
- 229910052739 hydrogen Inorganic materials 0.000 abstract 10
- 239000001257 hydrogen Substances 0.000 abstract 10
- 150000002431 hydrogen Chemical class 0.000 abstract 9
- -1 nitro, amino Chemical group 0.000 abstract 8
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 7
- 125000003118 aryl group Chemical group 0.000 abstract 7
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- 125000006310 cycloalkyl amino group Chemical group 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 1
- FCEHBMOGCRZNNI-UHFFFAOYSA-N 1-benzothiophene Chemical class C1=CC=C2SC=CC2=C1 FCEHBMOGCRZNNI-UHFFFAOYSA-N 0.000 abstract 1
- 125000003682 3-furyl group Chemical group O1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 abstract 1
- 125000005163 aryl sulfanyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000001907 coumarones Chemical class 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002140 imidazol-4-yl group Chemical group [H]N1C([H])=NC([*])=C1[H] 0.000 abstract 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/74—Naphthothiophenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7671298A | 1998-05-12 | 1998-05-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR015294A1 true AR015294A1 (es) | 2001-04-18 |
Family
ID=22133746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP990102229A AR015294A1 (es) | 1998-05-12 | 1999-05-12 | Benzotiofenos, benzofuranos e indoles, composicion farmaceutica que los contiene y su uso para la manufactura de un medicamento |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1077969A1 (no) |
| JP (1) | JP2002516321A (no) |
| KR (1) | KR20010043539A (no) |
| CN (1) | CN1308626A (no) |
| AR (1) | AR015294A1 (no) |
| AU (1) | AU756337B2 (no) |
| BG (1) | BG104918A (no) |
| BR (1) | BR9911779A (no) |
| CA (1) | CA2330620A1 (no) |
| EA (1) | EA200001175A1 (no) |
| EE (1) | EE200000653A (no) |
| HR (1) | HRP20000767A2 (no) |
| HU (1) | HUP0101792A3 (no) |
| ID (1) | ID26244A (no) |
| IL (1) | IL139132A0 (no) |
| NO (1) | NO20005677L (no) |
| PL (1) | PL344081A1 (no) |
| SK (1) | SK16992000A3 (no) |
| TR (1) | TR200003333T2 (no) |
| TW (1) | TW510900B (no) |
| WO (1) | WO1999061435A1 (no) |
| ZA (1) | ZA200005961B (no) |
Families Citing this family (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6472545B2 (en) | 2000-08-29 | 2002-10-29 | Abbott Laboratories | Protein tyrosine phosphatase inhibitors |
| WO2002018363A2 (en) * | 2000-08-29 | 2002-03-07 | Abbott Laboratories | 3-phenyl-propanoic acid derivatives as protein tyrosine phosphatase inhibitors |
| AU2001292518A1 (en) * | 2000-09-26 | 2002-04-08 | Biovitrum Ab | Novel compounds |
| US6498182B2 (en) | 2000-09-26 | 2002-12-24 | Biovitrum Ab | Compounds |
| US6969730B2 (en) | 2001-03-16 | 2005-11-29 | Abbott Laboratories | Amines as histamine-3 receptor ligands and their therapeutic applications |
| US20030022896A1 (en) * | 2001-06-07 | 2003-01-30 | Wyeth | PTPase inhibitors for improving cardiovascular risk profile |
| US20020198203A1 (en) * | 2001-06-07 | 2002-12-26 | Wyeth | Combination of a PTPase inhibitor and a thiazolidinedione agent |
| AR034375A1 (es) * | 2001-06-07 | 2004-02-18 | Wyeth Corp | Combinacion de un inhibidor de ptpasa y un agente de sulfonilurea |
| US6797693B2 (en) | 2001-06-07 | 2004-09-28 | Wyeth | Methods using PTPase inhibitors and insulin |
| US20030013709A1 (en) * | 2001-06-07 | 2003-01-16 | Wyeth | Combination of a PTPase inhibitor and an alpha-glucosidase inhibitor |
| US20020198202A1 (en) * | 2001-06-07 | 2002-12-26 | Wyeth | Combination of a PTPase inhibitor and an antilipemic agent |
| US6734197B2 (en) | 2001-06-07 | 2004-05-11 | Wyeth | Combination therapy for type II diabetes or Syndrome X |
| WO2002100398A1 (en) * | 2001-06-07 | 2002-12-19 | Wyeth | Combination of a ptpase inhibitor and an ace inhibitor |
| US20020198201A1 (en) * | 2001-06-07 | 2002-12-26 | Wyeth | Combination of a PTPase inhibitor and an aldose reductase inhibitor |
| TWI224101B (en) | 2001-06-20 | 2004-11-21 | Wyeth Corp | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
| US7074817B2 (en) | 2001-06-20 | 2006-07-11 | Wyeth | Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
| US7022730B2 (en) | 2001-10-19 | 2006-04-04 | Transtech Pharma, Inc. | Bis-heteroaryl alkanes as therapeutic agents |
| AU2002348276A1 (en) | 2001-11-16 | 2003-06-10 | Bristol-Myers Squibb Company | Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein |
| US7163952B2 (en) | 2001-12-03 | 2007-01-16 | Japan Tobacco Inc. | Azole compound and medicinal use thereof |
| ITMI20022172A1 (it) * | 2002-10-14 | 2004-04-15 | Clariant Lsm Italia Spa | Processo per la preparazione di 3-alchil-tiofeni-2, 5-disostituiti. |
| DE60306547T2 (de) | 2002-12-10 | 2007-06-28 | Wyeth | Substituierte 3-alkyl- und 3-arylalkyl-1h-indol-1-yl-essigsäure-derivate als plasminogen-aktivator |
| DE60306548T2 (de) | 2002-12-10 | 2007-06-21 | Wyeth | Substituierte 3-carbonyl-1-yl-essigsäure-derivate als plasminogen aktivator inhibitor(pai-1) inhibitoren |
| JP2006510673A (ja) | 2002-12-10 | 2006-03-30 | ワイス | プラスミノゲンアクティベータインヒビター１（ｐａｉ−１）のインヒビターとしての、アリール、アリールオキシ、および、アルキルオキシ置換１ｈ−インドール−３−イルグリオキシル酸誘導体 |
| DE60327550D1 (de) | 2002-12-10 | 2009-06-18 | Wyeth Corp | Substituierte indoloxoacetylaminoessigsäurederivate als inhibitoren des plasminogenaktivatorinhibitors-1 (pai-1) |
| UA80453C2 (en) | 2002-12-10 | 2007-09-25 | Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1) | |
| US7718377B2 (en) | 2003-05-29 | 2010-05-18 | Kyoto Pharmaceutical Industries, Ltd. | Insulin resistance curative and method of screening the same |
| US7504401B2 (en) | 2003-08-29 | 2009-03-17 | Locus Pharmaceuticals, Inc. | Anti-cancer agents and uses thereof |
| US7342039B2 (en) | 2003-09-25 | 2008-03-11 | Wyeth | Substituted indole oximes |
| US7332521B2 (en) | 2003-09-25 | 2008-02-19 | Wyeth | Substituted indoles |
| US7420083B2 (en) | 2003-09-25 | 2008-09-02 | Wyeth | Substituted aryloximes |
| US7582773B2 (en) | 2003-09-25 | 2009-09-01 | Wyeth | Substituted phenyl indoles |
| US7442805B2 (en) | 2003-09-25 | 2008-10-28 | Wyeth | Substituted sulfonamide-indoles |
| US7371759B2 (en) | 2003-09-25 | 2008-05-13 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
| US7268159B2 (en) | 2003-09-25 | 2007-09-11 | Wyeth | Substituted indoles |
| US7265148B2 (en) | 2003-09-25 | 2007-09-04 | Wyeth | Substituted pyrrole-indoles |
| US7411083B2 (en) | 2003-09-25 | 2008-08-12 | Wyeth | Substituted acetic acid derivatives |
| US7141592B2 (en) | 2003-09-25 | 2006-11-28 | Wyeth | Substituted oxadiazolidinediones |
| US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
| US7163954B2 (en) | 2003-09-25 | 2007-01-16 | Wyeth | Substituted naphthyl benzothiophene acids |
| US7446201B2 (en) | 2003-09-25 | 2008-11-04 | Wyeth | Substituted heteroaryl benzofuran acids |
| US7351726B2 (en) | 2003-09-25 | 2008-04-01 | Wyeth | Substituted oxadiazolidinediones |
| US7435837B2 (en) | 2003-10-24 | 2008-10-14 | Wyeth | Dihydrobenzofuranyl alkanamine derivatives and methods for using same |
| FR2862645B1 (fr) * | 2003-11-20 | 2007-06-22 | Merck Sante Sas | Composes antidiabetiques contenant des derives benzofuranes, benzothiophenes |
| US7420059B2 (en) | 2003-11-20 | 2008-09-02 | Bristol-Myers Squibb Company | HMG-CoA reductase inhibitors and method |
| AU2005277137A1 (en) | 2004-08-23 | 2006-03-02 | Wyeth | Pyrrolo-naphthyl acids as PAI-1 inhibitors |
| JP2008510815A (ja) | 2004-08-23 | 2008-04-10 | ワイス | 血栓症および心臓血管疾患の治療にて有用な調節剤であるプラスミノゲン活性化因子阻害剤１型（ｐａｉ−１）としてのオキサゾロ−ナフチル酸 |
| CA2577846A1 (en) | 2004-08-23 | 2006-03-02 | Wyeth | Thiazolo-naphthyl acids as inhibitors of plasminogen activator inhibitor-1 |
| CN101263115A (zh) | 2005-08-17 | 2008-09-10 | 惠氏公司 | 经取代吲哚和其用途 |
| US7879802B2 (en) | 2007-06-04 | 2011-02-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| AU2009256157B2 (en) | 2008-06-04 | 2014-12-18 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| GB0822486D0 (en) * | 2008-12-10 | 2009-01-14 | Univ Liverpool | Compounds for use in the treatment of pain |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9486433B2 (en) | 2012-10-12 | 2016-11-08 | Mochida Pharmaceuticals Co. Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
| US10441560B2 (en) | 2013-03-15 | 2019-10-15 | Mochida Pharmaceutical Co., Ltd. | Compositions and methods for treating non-alcoholic steatohepatitis |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| KR20150127599A (ko) | 2013-03-15 | 2015-11-17 | 모치다 세이야쿠 가부시키가이샤 | 비알코올성 지방간염을 치료하기 위한 조성물 및 방법 |
| JP2016514671A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼのアゴニストおよびその使用 |
| AU2014274812B2 (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| CN106749169B (zh) * | 2016-11-07 | 2020-04-21 | 浙江工业大学 | 一种Ertiprotafib的手性制备方法 |
| CN107033122B (zh) * | 2017-05-19 | 2019-06-14 | 南方医科大学 | 一种n-芳基-2-噻吩酰胺类衍生物及其制备方法和用途 |
| US20210115397A1 (en) | 2018-04-26 | 2021-04-22 | Tokyo Institute Of Technology | Method for promoting differentiation of pluripotent stem cells |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1242970A (en) * | 1968-08-15 | 1971-08-18 | Parke Davis & Co | NEW BENZO[b]THIOPHENEACETIC ACID COMPOUNDS AND METHODS FOR THEIR PRODUCTION |
| US3639422A (en) * | 1969-07-28 | 1972-02-01 | Parke Davis & Co | 4-phenylindole-1 (and 7)-acetic acids |
| US3682976A (en) * | 1970-02-16 | 1972-08-08 | Parke Davis & Co | Phenyl benzofuran acetic acid compounds |
| GB8417559D0 (en) * | 1984-07-10 | 1984-08-15 | Pfizer Ltd | Anti-diarrhoeal agents |
| FR2599740B1 (fr) * | 1986-06-05 | 1988-08-12 | Rhone Poulenc Sante | Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant |
| JPH01135766A (ja) * | 1987-11-20 | 1989-05-29 | Tanabe Seiyaku Co Ltd | ビフェニル誘導体 |
| US5110825A (en) * | 1989-12-28 | 1992-05-05 | Shionogi & Co., Ltd. | Benzofuran derivative |
| US5340833A (en) * | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
-
1999
- 1999-05-01 HR HR20000767A patent/HRP20000767A2/hr not_active Application Discontinuation
- 1999-05-10 PL PL99344081A patent/PL344081A1/xx not_active Application Discontinuation
- 1999-05-10 AU AU38939/99A patent/AU756337B2/en not_active Ceased
- 1999-05-10 JP JP2000550841A patent/JP2002516321A/ja active Pending
- 1999-05-10 CA CA002330620A patent/CA2330620A1/en not_active Abandoned
- 1999-05-10 TR TR2000/03333T patent/TR200003333T2/xx unknown
- 1999-05-10 HU HU0101792A patent/HUP0101792A3/hu unknown
- 1999-05-10 EP EP99921829A patent/EP1077969A1/en not_active Withdrawn
- 1999-05-10 BR BR9911779-7A patent/BR9911779A/pt not_active IP Right Cessation
- 1999-05-10 CN CN99808367A patent/CN1308626A/zh active Pending
- 1999-05-10 SK SK1699-2000A patent/SK16992000A3/sk unknown
- 1999-05-10 TW TW088107532A patent/TW510900B/zh active
- 1999-05-10 IL IL13913299A patent/IL139132A0/xx unknown
- 1999-05-10 ID IDW20002311A patent/ID26244A/id unknown
- 1999-05-10 EA EA200001175A patent/EA200001175A1/ru unknown
- 1999-05-10 WO PCT/US1999/010209 patent/WO1999061435A1/en not_active Ceased
- 1999-05-10 EE EEP200000653A patent/EE200000653A/xx unknown
- 1999-05-10 KR KR1020007012649A patent/KR20010043539A/ko not_active Withdrawn
- 1999-05-12 AR ARP990102229A patent/AR015294A1/es unknown
-
2000
- 2000-10-24 ZA ZA200005961A patent/ZA200005961B/xx unknown
- 2000-11-07 BG BG104918A patent/BG104918A/bg unknown
- 2000-11-10 NO NO20005677A patent/NO20005677L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU756337B2 (en) | 2003-01-09 |
| HUP0101792A2 (hu) | 2002-01-28 |
| HRP20000767A2 (en) | 2001-10-31 |
| IL139132A0 (en) | 2001-11-25 |
| EA200001175A1 (ru) | 2001-06-25 |
| CA2330620A1 (en) | 1999-12-02 |
| TR200003333T2 (tr) | 2001-02-21 |
| PL344081A1 (en) | 2001-09-24 |
| NO20005677L (no) | 2000-12-05 |
| WO1999061435A1 (en) | 1999-12-02 |
| EE200000653A (et) | 2002-04-15 |
| JP2002516321A (ja) | 2002-06-04 |
| BR9911779A (pt) | 2001-02-06 |
| NO20005677D0 (no) | 2000-11-10 |
| BG104918A (bg) | 2001-08-31 |
| KR20010043539A (ko) | 2001-05-25 |
| EP1077969A1 (en) | 2001-02-28 |
| AU3893999A (en) | 1999-12-13 |
| TW510900B (en) | 2002-11-21 |
| CN1308626A (zh) | 2001-08-15 |
| ID26244A (id) | 2000-12-07 |
| HUP0101792A3 (en) | 2003-01-28 |
| ZA200005961B (en) | 2001-10-24 |
| SK16992000A3 (sk) | 2001-04-09 |
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