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AR003929A1 - Composicion farmaceutica para compuestos piperidinoalcanol en forma de dosificacion unitaria solida y procedimientos para su preparacion - Google Patents

Composicion farmaceutica para compuestos piperidinoalcanol en forma de dosificacion unitaria solida y procedimientos para su preparacion

Info

Publication number
AR003929A1
AR003929A1 ARP960101530A AR10153096A AR003929A1 AR 003929 A1 AR003929 A1 AR 003929A1 AR P960101530 A ARP960101530 A AR P960101530A AR 10153096 A AR10153096 A AR 10153096A AR 003929 A1 AR003929 A1 AR 003929A1
Authority
AR
Argentina
Prior art keywords
preparation
pharmaceutical composition
unit dosage
solid unit
procedures
Prior art date
Application number
ARP960101530A
Other languages
English (en)
Original Assignee
Aventis Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27015322&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR003929(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Holdings Inc filed Critical Aventis Holdings Inc
Publication of AR003929A1 publication Critical patent/AR003929A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Se describe una composición farmacéutica en forma de dosificación unitaria sólida consistente en: a) una cantidad terapéuticamente efectiva de uncompuesto piperidinoalcanol o una sal del mismo farmacéuticamente aceptable y b) al menos uningredien te inerte. La presente invención proporciona ademásprocedimientos para la preparación de dicha composición farmacéutica, en particular se describe un procedimiento de granulación húmeda consistente en lapreparación de unagranulación húmeda do nde se mezclan un compuesto de fórmula (IIIa), donde X es un número que varía entre aproximadamente cero y 5, y susisómeros ópticos individuales, un diluyente y un desintegrante con una solución de un agente ligante;se tamiza la granulació n húmeda y se la seca;se combina dicha granulación seca con un lubricante y se comprime esta mezcla final para formar una tableta.
ARP960101530A 1995-02-28 1996-02-27 Composicion farmaceutica para compuestos piperidinoalcanol en forma de dosificacion unitaria solida y procedimientos para su preparacion AR003929A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39595295A 1995-02-28 1995-02-28
US55228795A 1995-12-12 1995-12-12

Publications (1)

Publication Number Publication Date
AR003929A1 true AR003929A1 (es) 1998-09-30

Family

ID=27015322

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960101530A AR003929A1 (es) 1995-02-28 1996-02-27 Composicion farmaceutica para compuestos piperidinoalcanol en forma de dosificacion unitaria solida y procedimientos para su preparacion

Country Status (22)

Country Link
US (9) US5738872A (es)
EP (1) EP0812195B1 (es)
JP (3) JP4105762B2 (es)
KR (1) KR100405116B1 (es)
CN (1) CN1090935C (es)
AR (1) AR003929A1 (es)
AT (1) ATE226819T1 (es)
AU (1) AU701042B2 (es)
CA (1) CA2213700C (es)
CL (1) CL2004000317A1 (es)
DE (1) DE69624559T2 (es)
DK (1) DK0812195T3 (es)
ES (1) ES2181868T3 (es)
FI (1) FI973518A0 (es)
HU (1) HUP9802086A3 (es)
IL (1) IL117237A (es)
MX (1) MX9706449A (es)
NO (2) NO325760B1 (es)
NZ (1) NZ302926A (es)
PT (1) PT812195E (es)
TW (1) TW460284B (es)
WO (1) WO1996026726A1 (es)

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CA2213700A1 (en) 1996-09-06
US5932247A (en) 1999-08-03
HUP9802086A3 (en) 2001-02-28
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JP4105762B2 (ja) 2008-06-25
ATE226819T1 (de) 2002-11-15
EP0812195A1 (en) 1997-12-17
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