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BR9713199A - Péletes de desintegração rápida - Google Patents

Péletes de desintegração rápida

Info

Publication number
BR9713199A
BR9713199A BR9713199-7A BR9713199A BR9713199A BR 9713199 A BR9713199 A BR 9713199A BR 9713199 A BR9713199 A BR 9713199A BR 9713199 A BR9713199 A BR 9713199A
Authority
BR
Brazil
Prior art keywords
pellets
contain
rapid disintegration
release rate
relates
Prior art date
Application number
BR9713199-7A
Other languages
English (en)
Inventor
Michaela Opitz
Hendrik Von Bueren
Rolf-Dieter Gabel
Geoffrey Lee
Original Assignee
Roche Diagnostics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7805374&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9713199(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Diagnostics Gmbh filed Critical Roche Diagnostics Gmbh
Publication of BR9713199A publication Critical patent/BR9713199A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Patente de Invenção: <B>"PéLETES DE DESINTEGRAçãO RáPIDA"<D>. A invenção refere-se a formas farmacêuticas de administração que estão na forma de péletes, as quais contêm um agente de retardo, na qual a taxa de liberação da substância ativa não é retardada ou é substancialmente idêntica comparada ao péletes correspondentes que não contêm agente de retardo. A taxa de liberação desses péletes de desintegração rápida é pelo menos cerca de 90% dentro de um período de tempo de 30 minutos. Além disso, a presente invenção também refere-se a processos para a produção desses péletes.
BR9713199-7A 1996-09-12 1997-09-09 Péletes de desintegração rápida BR9713199A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19637082A DE19637082A1 (de) 1996-09-12 1996-09-12 Schnellzerfallende Pellets
PCT/EP1997/004897 WO1998010754A1 (de) 1996-09-12 1997-09-09 Schnellzerfallende pellets

Publications (1)

Publication Number Publication Date
BR9713199A true BR9713199A (pt) 2000-04-04

Family

ID=7805374

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9713199-7A BR9713199A (pt) 1996-09-12 1997-09-09 Péletes de desintegração rápida

Country Status (18)

Country Link
US (2) US6224909B1 (pt)
EP (1) EP0925060B2 (pt)
JP (1) JP2001513752A (pt)
KR (1) KR100514467B1 (pt)
CN (1) CN1146409C (pt)
AR (1) AR012829A1 (pt)
AT (1) ATE228830T1 (pt)
AU (1) AU730673B2 (pt)
BR (1) BR9713199A (pt)
CA (1) CA2265766C (pt)
DE (2) DE19637082A1 (pt)
DK (1) DK0925060T3 (pt)
ES (1) ES2187822T5 (pt)
PT (1) PT925060E (pt)
TR (1) TR199901147T2 (pt)
TW (1) TW508250B (pt)
WO (1) WO1998010754A1 (pt)
ZA (1) ZA978171B (pt)

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US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
EP0968714A1 (de) * 1998-07-02 2000-01-05 Roche Diagnostics GmbH Verfahren zur Herstellung schnellauflösender pharmazeutischer Zubereitungen von schwerlöslichen Wirkstoffen
EP1069896B1 (en) * 1998-04-09 2003-08-06 Roche Diagnostics GmbH Carvedilol-galenics
US6852337B2 (en) * 1998-04-09 2005-02-08 Roche Diagnostics Gmbh Carvedilol-galenics
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
JP2002534455A (ja) * 1999-01-12 2002-10-15 メルク シャープ エンド ドーム リミテッド 疎水性物質及び水感受性物質のための球状化自己乳化系
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US8734850B2 (en) * 2003-11-25 2014-05-27 Flamel Technologies Oral medicinal product with modified release of at least one active principle in multimicrocapsular form
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Also Published As

Publication number Publication date
AU4553997A (en) 1998-04-02
ES2187822T3 (es) 2003-06-16
CA2265766A1 (en) 1998-03-19
JP2001513752A (ja) 2001-09-04
TR199901147T2 (xx) 1999-07-21
PT925060E (pt) 2003-04-30
ATE228830T1 (de) 2002-12-15
TW508250B (en) 2002-11-01
DE19637082A1 (de) 1998-03-19
EP0925060B2 (de) 2010-06-16
WO1998010754A1 (de) 1998-03-19
ZA978171B (en) 1999-03-11
DK0925060T3 (da) 2003-04-07
ES2187822T5 (es) 2010-10-28
EP0925060B1 (de) 2002-12-04
US6379706B2 (en) 2002-04-30
US20010004458A1 (en) 2001-06-21
KR100514467B1 (ko) 2005-09-15
EP0925060A1 (de) 1999-06-30
DE59708898D1 (de) 2003-01-16
CA2265766C (en) 2006-04-25
CN1146409C (zh) 2004-04-21
AU730673B2 (en) 2001-03-08
US6224909B1 (en) 2001-05-01
CN1237104A (zh) 1999-12-01
KR20000036013A (ko) 2000-06-26
AR012829A1 (es) 2000-11-22

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA, DE ACORDO COM O ARTIGO 8O, COMBINADO COM O ARTIGO 13, DA LPI 9279, DE 14/05/1996

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