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AR003446A1 - Peptidos derivados de la proteina 60 humana por shock termico para diagnosis y tratamiento de diabetes, las composiciones farmaceuticas y los metodos para diagnosticar - Google Patents

Peptidos derivados de la proteina 60 humana por shock termico para diagnosis y tratamiento de diabetes, las composiciones farmaceuticas y los metodos para diagnosticar

Info

Publication number
AR003446A1
AR003446A1 ARP960103410A AR10341096A AR003446A1 AR 003446 A1 AR003446 A1 AR 003446A1 AR P960103410 A ARP960103410 A AR P960103410A AR 10341096 A AR10341096 A AR 10341096A AR 003446 A1 AR003446 A1 AR 003446A1
Authority
AR
Argentina
Prior art keywords
diagnosis
treatment
diagnosing
pharmaceutical compositions
diabetes
Prior art date
Application number
ARP960103410A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of AR003446A1 publication Critical patent/AR003446A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2/00Peptides of undefined number of amino acids; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/975Kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Un péptido derivado de la proteína 60 humana por shock térmico para el diagnóstico y tratamiento de diabetes caracterizado porque está seleccionadode los siguientes péptidos identificados y sus sales y derivados funcionales. Pueden utilizarsepéptidos nuevos que son epítopes de la proteína por choquetérmico 60 KDa (hsp 60) para el diagnóstico y tratamiento de la diabetes mellitus insulina-dependiente (DMID) que contiene a estos péptidos y tambiénse describen los equipos parautiliz ar en el diagnóstico de DMID. Además describen métodos para diagnosticar composiciones farmacéuticas, equipos dediagnóstico y uso de dichos antígenos para la fabricación de un equipo de diagnóstico.
ARP960103410A 1995-06-30 1996-07-01 Peptidos derivados de la proteina 60 humana por shock termico para diagnosis y tratamiento de diabetes, las composiciones farmaceuticas y los metodos para diagnosticar AR003446A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11440795A IL114407A0 (en) 1995-06-30 1995-06-30 Novel peptides and pharmaceutical compositions comprising them

Publications (1)

Publication Number Publication Date
AR003446A1 true AR003446A1 (es) 1998-08-05

Family

ID=11067704

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103410A AR003446A1 (es) 1995-06-30 1996-07-01 Peptidos derivados de la proteina 60 humana por shock termico para diagnosis y tratamiento de diabetes, las composiciones farmaceuticas y los metodos para diagnosticar

Country Status (19)

Country Link
US (1) US6682897B1 (es)
EP (1) EP0845943B1 (es)
KR (1) KR100454554B1 (es)
CN (1) CN1102598C (es)
AR (1) AR003446A1 (es)
AT (1) ATE290315T1 (es)
AU (1) AU710882B2 (es)
CA (1) CA2225675C (es)
CZ (1) CZ295110B6 (es)
DE (1) DE69634438T2 (es)
DK (1) DK0845943T3 (es)
ES (1) ES2239770T3 (es)
HR (1) HRP960307A2 (es)
HU (1) HUP9901688A3 (es)
IL (2) IL114407A0 (es)
NO (1) NO320715B1 (es)
UY (1) UY24270A1 (es)
WO (1) WO1997001959A1 (es)
ZA (1) ZA965565B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6488933B2 (en) 1995-07-05 2002-12-03 Yeda Research And Development Co. Ltd. Preparations for the treatment of T cell mediated diseases
US6451541B1 (en) * 1996-05-14 2002-09-17 Ernst-Ludwig Winnacker Chaperones capable of binding to prion proteins and distinguishing the isoforms PrPc and PrPsc
US5993803A (en) * 1996-08-30 1999-11-30 Yeda Research And Development Co., Ltd. Method of reducing the severity of host vs graft reaction by down-regulating hsp60 autoimmunity
NZ519348A (en) * 1999-12-15 2006-04-28 Develogen Israel Ltd Fragments and antagonists of heat shock protein 60
JP2005503320A (ja) * 2000-08-25 2005-02-03 イエダ・リサーチ・アンド・デベロツプメント・カンパニー・リミテツド CpG−含有ポリヌクレオチドで自己免疫疾患を処置または防止する方法
ES2526822T3 (es) 2002-01-31 2015-01-15 Andromeda Bio Tech Ltd. Péptidos hsp y análogos para la modulación de respuestas inmunes mediante células presentadoras de antígeno
AU2003209623A1 (en) * 2002-02-19 2003-09-09 Yeda Research And Development Co. Ltd. Dual-effect ligands comprising anti-inflammatory hsp peptide epitopes for immunomodulation
ES2433915T3 (es) 2002-05-21 2013-12-13 Irun R. Cohen Vacunas de ADN que codifican proteínas de choque térmico
WO2004098489A2 (en) * 2003-05-12 2004-11-18 Peptor Ltd. Compositions and methods for modulation of specific epitopes of hsp60
US20090202618A1 (en) * 2003-11-24 2009-08-13 Yeda Research & Development Co. Ltd Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases
EP1718158B1 (en) 2004-01-28 2014-07-02 Andromeda Bio Tech Ltd. Hsp therapy in conjunction with a low antigenicity diet
WO2006072946A2 (en) * 2005-01-04 2006-07-13 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Hsp60, hsp60 peptides and t cell vaccines for immunomodulation
CU23701A1 (es) * 2008-12-29 2011-09-21 Ct Ingenieria Genetica Biotech Método de tratamiento de enfermedades inflamatorias intestinales y diabetes tipo i
US9102942B2 (en) 2010-02-04 2015-08-11 EWHA University—Industry Collaboration Foundation Pharmaceutical composition for inhibiting abnormal proliferation of cells
ITCO20120007A1 (it) 2012-02-21 2013-08-22 Nuovo Pignone Srl Dispositivo di filtraggio dell'aria in ingresso per un impianto
WO2013128453A1 (en) 2012-03-01 2013-09-06 Yeda Research And Development Co. Ltd. Regeneration of islet beta cells by hsp60 derived peptides
WO2013128450A1 (en) 2012-03-01 2013-09-06 Yeda Research And Development Co. Ltd. Hsp60 derived peptides and peptide analogs for suppression and treatment of non-autoimmune diabetes
EP3448415A4 (en) * 2016-04-29 2019-11-06 Araim Pharmaceuticals, Inc. TREATMENT-PROOFING PEPTIDES FOR THE PREVENTION AND TREATMENT OF DISEASES AND DISORDERS RELATED TO TISSUE DAMAGE
CN111035755B (zh) * 2020-01-08 2023-04-14 中国医学科学院医学生物学研究所 一种1型糖尿病疫苗及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242823A (en) * 1986-03-07 1993-09-07 International Genetic Engineering, Inc. Cloning of the 38kd Mycoplasma hyorhinis regression-associated antigen
US4976958A (en) * 1987-02-26 1990-12-11 Scripps Clinic And Research Foundation Mycobacterial recombinants and peptides
US5114844A (en) * 1989-03-14 1992-05-19 Yeda Research And Development Co., Ltd. Diagnosis and treatment of insulin dependent diabetes mellitus

Also Published As

Publication number Publication date
ZA965565B (en) 1997-02-26
EP0845943B1 (en) 2005-03-09
HUP9901688A3 (en) 1999-12-28
EP0845943A4 (en) 2002-04-10
IL114407A0 (en) 1995-10-31
CA2225675A1 (en) 1997-01-23
CZ411797A3 (cs) 1998-06-17
DK0845943T3 (da) 2005-07-11
IL122757A (en) 2001-07-24
ATE290315T1 (de) 2005-03-15
CN1102598C (zh) 2003-03-05
US6682897B1 (en) 2004-01-27
HUP9901688A2 (hu) 1999-09-28
NO976094L (no) 1998-02-02
KR19990028640A (ko) 1999-04-15
AU710882B2 (en) 1999-09-30
NO320715B1 (no) 2006-01-23
JP3955627B2 (ja) 2007-08-08
WO1997001959A1 (en) 1997-01-23
AU6484596A (en) 1997-02-05
UY24270A1 (es) 2000-12-29
JPH11509196A (ja) 1999-08-17
NO976094D0 (no) 1997-12-29
CZ295110B6 (cs) 2005-05-18
MX9800191A (es) 1998-05-31
HRP960307A2 (en) 1998-04-30
CA2225675C (en) 2010-09-21
IL122757A0 (en) 1998-08-16
DE69634438D1 (de) 2005-04-14
DE69634438T2 (de) 2006-02-09
KR100454554B1 (ko) 2005-04-06
EP0845943A1 (en) 1998-06-10
ES2239770T3 (es) 2005-10-01
CN1193889A (zh) 1998-09-23

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