AR008605A1 - Procedimiento para preparar clavulanato de potasio, clavulanato de potasio en la forma de estrellas reventadas a modo de rosetas cristalinas, unacomposicion farmaceutica que lo contiene, el uso del mismo para la preparacion de un medicamento para tratar infecciones bacterianas. - Google Patents
Procedimiento para preparar clavulanato de potasio, clavulanato de potasio en la forma de estrellas reventadas a modo de rosetas cristalinas, unacomposicion farmaceutica que lo contiene, el uso del mismo para la preparacion de un medicamento para tratar infecciones bacterianas.Info
- Publication number
- AR008605A1 AR008605A1 ARP970102612A ARP970102612A AR008605A1 AR 008605 A1 AR008605 A1 AR 008605A1 AR P970102612 A ARP970102612 A AR P970102612A AR P970102612 A ARP970102612 A AR P970102612A AR 008605 A1 AR008605 A1 AR 008605A1
- Authority
- AR
- Argentina
- Prior art keywords
- potassium clavulanate
- crystalline
- stars
- procedure
- preparation
- Prior art date
Links
- ABVRVIZBZKUTMK-JSYANWSFSA-M potassium clavulanate Chemical compound [K+].[O-]C(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 ABVRVIZBZKUTMK-JSYANWSFSA-M 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Se describe una nueva forma cristalina del calvulanato de potasio en la forma de estrella reventada cristalina del clavulanato de potasio y de la formade roseta cristalina del clavulanato de potasio. También se describen un procedimientop ara producir la nueva forma cristalina del clavulanato depotasio, composiciones farmacéuticas que lo contienen y el uso de clavulanato de potasio en la forma de estrellas reventadas a modo de rosetas cristalinaspara la preparacion de unmedicamento util para tratar infecciones bacterianas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2048096P | 1996-06-13 | 1996-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR008605A1 true AR008605A1 (es) | 2000-02-09 |
Family
ID=21798851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP970102612A AR008605A1 (es) | 1996-06-13 | 1997-06-13 | Procedimiento para preparar clavulanato de potasio, clavulanato de potasio en la forma de estrellas reventadas a modo de rosetas cristalinas, unacomposicion farmaceutica que lo contiene, el uso del mismo para la preparacion de un medicamento para tratar infecciones bacterianas. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6414142B1 (es) |
| EP (1) | EP0918520A4 (es) |
| JP (1) | JP2000512297A (es) |
| KR (1) | KR20000016544A (es) |
| CN (1) | CN1115147C (es) |
| AR (1) | AR008605A1 (es) |
| AU (1) | AU712904B2 (es) |
| BR (1) | BR9711803A (es) |
| CO (1) | CO4970806A1 (es) |
| CZ (1) | CZ407298A3 (es) |
| IL (1) | IL127415A (es) |
| NO (1) | NO985824L (es) |
| NZ (1) | NZ333177A (es) |
| PL (1) | PL186484B1 (es) |
| TR (1) | TR199802452T2 (es) |
| TW (1) | TW477700B (es) |
| WO (1) | WO1997047301A1 (es) |
| ZA (1) | ZA975198B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT400033B (de) | 1992-03-10 | 1995-09-25 | Biochemie Gmbh | Neues verfahren zur isolierung und reinigung von clavulansäure und zur herstellung von pharmakologisch verträglichen salzen derselben |
| AT403375B (de) * | 1995-11-15 | 1998-01-26 | Biochemie Gmbh | Verfahren zur fällung von alkalisalzen der clavulansäure |
| AU1234999A (en) * | 1997-11-10 | 1999-05-31 | Gist-Brocades B.V. | Crystallization of beta-lactam compounds |
| CA2364342C (en) * | 1999-04-01 | 2011-02-01 | Dsm N.V. | Agglomerates by crystallisation |
| KR20080038224A (ko) * | 2006-07-20 | 2008-05-02 | 시코르, 인크. | 고체 멸균 유효 약리 성분의 제조 방법 |
| WO2011152807A1 (en) | 2010-06-03 | 2011-12-08 | Bilgic Mahmut | Pharmaceutical formulation comprising cefpodoxime proxetil and clavulanic acid |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1508977A (en) * | 1974-04-20 | 1978-04-26 | Beecham Group Ltd | Beta-lactam antibiotic from streptomyces clavuligerus |
| GB1543563A (en) * | 1975-02-07 | 1979-04-04 | Glaxo Lab Ltd | Beta-lactam antibiotic in purified form |
| DE3063683D1 (en) | 1979-08-24 | 1983-07-14 | Beecham Group Plc | Amine salt of clavulanic acid, its preparation and use |
| US4454069A (en) * | 1979-08-24 | 1984-06-12 | Beecham Group Limited | Clavulanic acid salts and their preparation from the tertiary butyl amine salt |
| PT86631B (pt) | 1987-01-29 | 1992-01-31 | Beecham Group Plc | Processo para a preparacao de uma nova forma cristalina de clavulanato de potassio |
| US5288861A (en) * | 1987-01-29 | 1994-02-22 | Beecham Group Plc | Potassium clavulanate in rosette form |
| AT399155B (de) * | 1992-03-26 | 1995-03-27 | Lek Tovarna Farmacevtskih | Neue alkylendiammonium-diclavulanat-derivate, verfahren zu deren herstellung sowie deren verwendung |
| SI9300296B (sl) | 1992-06-11 | 1998-06-30 | Smithkline Beecham P.L.C. | Postopek in intermedianti za pripravo klavulanske kisline |
| GB9305565D0 (en) | 1993-03-18 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds and processes |
| US5821364A (en) * | 1993-03-26 | 1998-10-13 | Gist-Brocades N.V. | Diamine salts of clavulanic acid |
| JPH06298779A (ja) | 1993-04-15 | 1994-10-25 | Hoechst Japan Ltd | ヘテロ環イミノビスメチレンビスホスホン酸誘導体 |
| GB9401969D0 (en) | 1994-02-02 | 1994-03-30 | Smithkline Beecham Plc | Process |
| SI9400107A (en) * | 1994-03-02 | 1995-10-31 | Lek Tovarna Farmacevtskih | New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804. |
| FI973287L (fi) * | 1995-02-25 | 1997-08-22 | Spurcourt Ltd | Klavulaanihapposuoloja |
| GB9515809D0 (en) | 1995-08-02 | 1995-10-04 | Smithkline Beecham Plc | Process |
-
1997
- 1997-06-12 ZA ZA9705198A patent/ZA975198B/xx unknown
- 1997-06-12 US US08/973,936 patent/US6414142B1/en not_active Expired - Fee Related
- 1997-06-13 EP EP97929994A patent/EP0918520A4/en not_active Withdrawn
- 1997-06-13 KR KR1019980710132A patent/KR20000016544A/ko not_active Ceased
- 1997-06-13 IL IL12741597A patent/IL127415A/xx not_active IP Right Cessation
- 1997-06-13 CO CO97032866A patent/CO4970806A1/es unknown
- 1997-06-13 CZ CZ984072A patent/CZ407298A3/cs unknown
- 1997-06-13 TR TR1998/02452T patent/TR199802452T2/xx unknown
- 1997-06-13 AR ARP970102612A patent/AR008605A1/es not_active Application Discontinuation
- 1997-06-13 JP JP10501867A patent/JP2000512297A/ja not_active Ceased
- 1997-06-13 NZ NZ333177A patent/NZ333177A/xx not_active IP Right Cessation
- 1997-06-13 CN CN97197156A patent/CN1115147C/zh not_active Expired - Fee Related
- 1997-06-13 AU AU33927/97A patent/AU712904B2/en not_active Ceased
- 1997-06-13 WO PCT/US1997/010317 patent/WO1997047301A1/en not_active Ceased
- 1997-06-13 BR BR9711803A patent/BR9711803A/pt not_active Application Discontinuation
- 1997-09-15 TW TW086108391A patent/TW477700B/zh not_active IP Right Cessation
-
1998
- 1998-12-11 NO NO985824A patent/NO985824L/no not_active Application Discontinuation
-
1999
- 1999-02-09 PL PL97330639A patent/PL186484B1/pl not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| TW477700B (en) | 2002-03-01 |
| NO985824L (no) | 1999-02-10 |
| AU712904B2 (en) | 1999-11-18 |
| ZA975198B (en) | 1997-12-15 |
| NO985824D0 (no) | 1998-12-11 |
| CN1227488A (zh) | 1999-09-01 |
| US6414142B1 (en) | 2002-07-02 |
| CZ407298A3 (cs) | 1999-05-12 |
| AU3392797A (en) | 1998-01-07 |
| KR20000016544A (ko) | 2000-03-25 |
| CO4970806A1 (es) | 2000-11-07 |
| NZ333177A (en) | 2000-05-26 |
| JP2000512297A (ja) | 2000-09-19 |
| PL330639A1 (en) | 1999-05-24 |
| IL127415A0 (en) | 1999-10-28 |
| PL186484B1 (pl) | 2004-01-30 |
| IL127415A (en) | 2003-10-31 |
| EP0918520A4 (en) | 2000-01-12 |
| EP0918520A1 (en) | 1999-06-02 |
| WO1997047301A1 (en) | 1997-12-18 |
| BR9711803A (pt) | 1999-08-24 |
| CN1115147C (zh) | 2003-07-23 |
| TR199802452T2 (xx) | 1999-02-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |