AP3691A - Use of the combination of an inhibitor of the if current of the sinoatrial node and an inhibitor of the angiotensin-converting enzyme for treating heart failure - Google Patents

Use of the combination of an inhibitor of the if current of the sinoatrial node and an inhibitor of the angiotensin-converting enzyme for treating heart failure

Info

Publication number: AP3691A
Authority: AP; ARIPO
Prior art keywords: inhibitor; angiotensin; combination; current; heart failure
Prior art date: 2010-06-15

Application number

AP2013006661A

Other languages

English (en)

Other versions

AP2013006661A0 (en

Inventor

Paulus Mulder

Luc Feldmann

Guy Lerebours-Pigeonniere

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-06-15

Filing date

2011-06-14

Publication date

2016-04-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42985210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3691(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-06-14 Application filed by Servier Lab filed Critical Servier Lab

2013-01-31 Publication of AP2013006661A0 publication Critical patent/AP2013006661A0/xx

2016-04-30 Application granted granted Critical

2016-04-30 Publication of AP3691A publication Critical patent/AP3691A/xx

Links

239000003112 inhibitor Substances 0.000 title 2
UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 title 1
206010019280 Heart failures Diseases 0.000 title 1
102000004270 Peptidyl-Dipeptidase A Human genes 0.000 title 1
108090000882 Peptidyl-Dipeptidase A Proteins 0.000 title 1
210000001013 sinoatrial node Anatomy 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Display Devices Of Pinball Game Machines (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)

AP2013006661A 2010-06-15 2011-06-14 Use of the combination of an inhibitor of the if current of the sinoatrial node and an inhibitor of the angiotensin-converting enzyme for treating heart failure AP3691A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR1002525A FR2961105B1 (fr)	2010-06-15	2010-06-15	Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque
PCT/FR2011/000345 WO2011157908A1 (fr)	2010-06-15	2011-06-14	Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque

Publications (2)

Publication Number	Publication Date
AP2013006661A0 AP2013006661A0 (en)	2013-01-31
AP3691A true AP3691A (en)	2016-04-30

Family

ID=42985210

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AP2013006661A AP3691A (en)	2010-06-15	2011-06-14	Use of the combination of an inhibitor of the if current of the sinoatrial node and an inhibitor of the angiotensin-converting enzyme for treating heart failure
AP2016009002A AP2016009002A0 (en)	2010-06-15	2011-06-14	Use of a combination of an inhibitor of the if current of the sinus node and an inhibitor of the angiotensin converting enzyme for the treatment of heart failure

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AP2016009002A AP2016009002A0 (en)	2010-06-15	2011-06-14	Use of a combination of an inhibitor of the if current of the sinus node and an inhibitor of the angiotensin converting enzyme for the treatment of heart failure

Country Status (47)

Country	Link
US (1)	US20110306598A1 (es)
EP (2)	EP2921168B1 (es)
JP (1)	JP5480202B2 (es)
KR (1)	KR101389879B1 (es)
CN (2)	CN104906579A (es)
AP (2)	AP3691A (es)
AR (1)	AR081875A1 (es)
AU (1)	AU2011202607B2 (es)
BR (1)	BRPI1102830F1 (es)
CA (1)	CA2743527C (es)
CL (1)	CL2011001420A1 (es)
CO (1)	CO6640265A2 (es)
CR (1)	CR20120609U (es)
CU (1)	CU24161B1 (es)
CY (2)	CY1116438T1 (es)
DK (2)	DK2404600T3 (es)
EA (1)	EA022612B1 (es)
EC (1)	ECSP12012337A (es)
ES (2)	ES2582157T3 (es)
FR (1)	FR2961105B1 (es)
GE (1)	GEP20146132B (es)
GT (1)	GT201200341A (es)
HK (1)	HK1210012A1 (es)
HR (2)	HRP20150745T1 (es)
HU (2)	HUE027088T2 (es)
IL (1)	IL223293A (es)
JO (1)	JO3309B1 (es)
MA (1)	MA33235B1 (es)
ME (2)	ME02476B (es)
MX (1)	MX2011006001A (es)
MY (1)	MY179034A (es)
NI (1)	NI201200182A (es)
NZ (2)	NZ593437A (es)
PE (1)	PE20120019A1 (es)
PH (1)	PH12012502315B1 (es)
PL (2)	PL2404600T3 (es)
PT (1)	PT2404600E (es)
RS (2)	RS54838B1 (es)
SA (2)	SA114360089B1 (es)
SG (2)	SG177069A1 (es)
SI (2)	SI2921168T1 (es)
TN (1)	TN2012000551A1 (es)
TW (1)	TWI468164B (es)
UA (1)	UA108983C2 (es)
UY (1)	UY33423A (es)
WO (1)	WO2011157908A1 (es)
ZA (1)	ZA201104222B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102603666A (zh) *	2012-02-28	2012-07-25	石河子大学	肉桂酰牛磺酰噻唑烷酸类化合物及其应用
FR3020810B1 (fr) *	2014-05-06	2016-05-06	Servier Lab	Nouveau sel de l'ivabradine et son procede de preparation.
EP3025705B8 (en) *	2014-11-25	2018-11-28	Sanofi Ilaç Sanayi ve Ticaret Anonim Sirketi	Stable ivabradine formulations
PH12018502155B1 (en)	2016-04-20	2024-03-27	Servier Lab	Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid
KR20190001340A (ko) *	2017-06-27	2019-01-04	에리슨제약(주)	이바브라딘을 포함하는 서방성 약제학적 조성물 및 이의 제조방법
CN107714702A (zh) *	2017-10-31	2018-02-23	泰州中国医药城中医药研究院	一种伊伐布雷定和米力农组合物及其在制药中的应用
CN107550915A (zh) *	2017-10-31	2018-01-09	泰州中国医药城中医药研究院	一种伊伐布雷定和咯利普兰组合物及其在制药中的应用

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WO2001078699A2 (de) *	2000-04-13	2001-10-25	Boehringer Ingelheim Pharma Kg	Verwendung von bradycardica bei der behandlung von mit hypertrophie einhergehenden myocarderkrankungen und neue arzneimittelkombinationen
EP1354873A1 (fr) *	2002-04-18	2003-10-22	Les Laboratoires Servier	Sel de périndopril et les compositions pharmaceutiques qui le contiennent
EP1362590A1 (en) *	2002-07-25	2003-11-19	Boehringer Ingelheim Pharma GmbH & Co.KG	Use of cilobradine or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
EP2036892A1 (fr) *	2007-09-11	2009-03-18	Les Laboratoires Servier	Dérivés de 1,2,4,5-tétrahydro-3H-benzazépines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP2039682A1 (fr) *	2007-09-21	2009-03-25	Les Laboratoires Servier	Sels d'addition d'inhibiteurs d'enzyme de conversion de l'angiotensine à des acides donneurs de NO, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
RU2364401C1 (ru) *	2008-05-12	2009-08-20	Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию"	Способ коррекции сосудистого ремоделирования у больных хронической сердечной недостаточностью ишемической этиологии

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FR2681862B1 (fr)	1991-09-27	1993-11-12	Adir Cie	Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
US6188743B1 (en) *	1997-10-10	2001-02-13	Analogic Corporation	Computed tomography scanner drive system and bearing
FR2807431B1 (fr) *	2000-04-06	2002-07-19	Adir	Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables
EP1799199B1 (en) *	2004-10-08	2012-03-28	Novartis AG	Use of renin inhibitors for the prevention or treatment of diastolic dysfunction or diastolic heart failure
WO2007014051A2 (en) *	2005-07-22	2007-02-01	Amylin Pharmaceuticals, Inc.	Use of amylin and amylin agonists as cardioprotective or myoprotective agents
FR2891826B1 (fr) *	2005-10-11	2007-12-28	Servier Lab	Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2894825B1 (fr)	2005-12-21	2010-12-03	Servier Lab	Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent
FR2911279B1 (fr) *	2007-01-11	2009-03-06	Servier Lab	Utilisation de l'ivabradine pour l'obtention de medicaments destines au traitement de la dysfonction endotheliale
FR2927538B1 (fr) *	2008-02-14	2010-02-19	Servier Lab	Association d'un inhibiteur du courant if sinusal et d'un beta-bloquant.
WO2009158005A1 (en) *	2008-06-27	2009-12-30	Concert Pharmaceuticals, Inc.	Benzazepinone compounds
RU2382644C1 (ru) *	2008-11-05	2010-02-27	Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию"	Способ коррекции гипертрофии левого желудочка у больных ибс в сочетании с гипертонической болезнью

2010
- 2010-06-15 FR FR1002525A patent/FR2961105B1/fr not_active Expired - Fee Related
2011
- 2011-05-31 JO JOP/2011/0178A patent/JO3309B1/ar active
- 2011-05-31 PE PE2011001126A patent/PE20120019A1/es not_active Application Discontinuation
- 2011-05-31 SG SG2011039419A patent/SG177069A1/en unknown
- 2011-05-31 AU AU2011202607A patent/AU2011202607B2/en not_active Ceased
- 2011-05-31 SG SG10201500502WA patent/SG10201500502WA/en unknown
- 2011-06-01 MY MYPI2011002498A patent/MY179034A/en unknown
- 2011-06-02 UY UY0001033423A patent/UY33423A/es not_active Application Discontinuation
- 2011-06-07 ZA ZA2011/04222A patent/ZA201104222B/en unknown
- 2011-06-07 MX MX2011006001A patent/MX2011006001A/es active IP Right Grant
- 2011-06-08 MA MA33924A patent/MA33235B1/fr unknown
- 2011-06-09 TW TW100120215A patent/TWI468164B/zh not_active IP Right Cessation
- 2011-06-10 GE GEAP201112259A patent/GEP20146132B/en unknown
- 2011-06-10 CL CL2011001420A patent/CL2011001420A1/es unknown
- 2011-06-10 CA CA2743527A patent/CA2743527C/fr not_active Expired - Fee Related
- 2011-06-13 NZ NZ593437A patent/NZ593437A/xx not_active IP Right Cessation
- 2011-06-13 SA SA114360089A patent/SA114360089B1/ar unknown
- 2011-06-13 AR ARP110102044A patent/AR081875A1/es unknown
- 2011-06-13 NZ NZ600931A patent/NZ600931A/xx not_active IP Right Cessation
- 2011-06-13 SA SA111320527A patent/SA111320527B1/ar unknown
- 2011-06-14 CU CU20120166A patent/CU24161B1/es active IP Right Grant
- 2011-06-14 RS RS20160422A patent/RS54838B1/sr unknown
- 2011-06-14 PT PT112902697T patent/PT2404600E/pt unknown
- 2011-06-14 KR KR1020110057585A patent/KR101389879B1/ko not_active Expired - Fee Related
- 2011-06-14 SI SI201130879A patent/SI2921168T1/sl unknown
- 2011-06-14 US US13/134,667 patent/US20110306598A1/en not_active Abandoned
- 2011-06-14 UA UAA201107469A patent/UA108983C2/en unknown
- 2011-06-14 PH PH1/2012/502315A patent/PH12012502315B1/en unknown
- 2011-06-14 EP EP15162899.7A patent/EP2921168B1/fr active Active
- 2011-06-14 HU HUE11290269A patent/HUE027088T2/en unknown
- 2011-06-14 SI SI201130568T patent/SI2404600T1/sl unknown
- 2011-06-14 ES ES15162899.7T patent/ES2582157T3/es active Active
- 2011-06-14 ES ES11290269.7T patent/ES2545343T3/es active Active
- 2011-06-14 DK DK11290269.7T patent/DK2404600T3/en active
- 2011-06-14 AP AP2013006661A patent/AP3691A/xx active
- 2011-06-14 DK DK15162899.7T patent/DK2921168T3/en active
- 2011-06-14 PL PL11290269T patent/PL2404600T3/pl unknown
- 2011-06-14 HU HUE15162899A patent/HUE027788T2/en unknown
- 2011-06-14 EP EP11290269.7A patent/EP2404600B1/fr not_active Revoked
- 2011-06-14 ME MEP-2016-90A patent/ME02476B/me unknown
- 2011-06-14 EA EA201100773A patent/EA022612B1/ru unknown
- 2011-06-14 RS RS20150435A patent/RS54077B1/sr unknown
- 2011-06-14 ME MEP-2015-95A patent/ME02163B/me unknown
- 2011-06-14 WO PCT/FR2011/000345 patent/WO2011157908A1/fr not_active Ceased
- 2011-06-14 AP AP2016009002A patent/AP2016009002A0/xx unknown
- 2011-06-14 PL PL15162899.7T patent/PL2921168T3/pl unknown
- 2011-06-14 BR BRPI1102830A patent/BRPI1102830F1/pt not_active IP Right Cessation
- 2011-06-15 JP JP2011132849A patent/JP5480202B2/ja active Active
- 2011-06-15 CN CN201510337337.6A patent/CN104906579A/zh active Pending
- 2011-06-15 CN CN2011101600748A patent/CN102284060A/zh active Pending
2012
- 2012-11-23 TN TNP2012000551A patent/TN2012000551A1/fr unknown
- 2012-11-27 IL IL223293A patent/IL223293A/en active IP Right Grant
- 2012-12-03 CR CR20120609U patent/CR20120609U/es unknown
- 2012-12-07 NI NI201200182A patent/NI201200182A/es unknown
- 2012-12-10 CO CO12223070A patent/CO6640265A2/es not_active Application Discontinuation
- 2012-12-14 GT GT201200341A patent/GT201200341A/es unknown
- 2012-12-14 EC ECSP12012337 patent/ECSP12012337A/es unknown
2015
- 2015-06-08 CY CY20151100503T patent/CY1116438T1/el unknown
- 2015-07-08 HR HRP20150745TT patent/HRP20150745T1/hr unknown
- 2015-10-28 HK HK15110661.0A patent/HK1210012A1/xx unknown
2016
- 2016-06-09 HR HRP20160643TT patent/HRP20160643T1/hr unknown
- 2016-06-10 CY CY20161100508T patent/CY1117724T1/el unknown

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001078699A2 (de) *	2000-04-13	2001-10-25	Boehringer Ingelheim Pharma Kg	Verwendung von bradycardica bei der behandlung von mit hypertrophie einhergehenden myocarderkrankungen und neue arzneimittelkombinationen
EP1354873A1 (fr) *	2002-04-18	2003-10-22	Les Laboratoires Servier	Sel de périndopril et les compositions pharmaceutiques qui le contiennent
EP1362590A1 (en) *	2002-07-25	2003-11-19	Boehringer Ingelheim Pharma GmbH & Co.KG	Use of cilobradine or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
EP2036892A1 (fr) *	2007-09-11	2009-03-18	Les Laboratoires Servier	Dérivés de 1,2,4,5-tétrahydro-3H-benzazépines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
EP2039682A1 (fr) *	2007-09-21	2009-03-25	Les Laboratoires Servier	Sels d'addition d'inhibiteurs d'enzyme de conversion de l'angiotensine à des acides donneurs de NO, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
RU2364401C1 (ru) *	2008-05-12	2009-08-20	Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию"	Способ коррекции сосудистого ремоделирования у больных хронической сердечной недостаточностью ишемической этиологии

Also Published As

Publication number	Publication date
BRPI1102830F1 (pt)	2022-03-29
AR081875A1 (es)	2012-10-24
CA2743527A1 (fr)	2011-12-15
CR20120609U (es)	2013-02-05
JP2012001545A (ja)	2012-01-05
HK1210011A1 (zh)	2016-04-15
SA111320527B1 (ar)	2015-03-19
ES2582157T3 (es)	2016-09-09
TN2012000551A1 (fr)	2014-04-01
MA33235B1 (fr)	2012-05-02
PL2921168T3 (pl)	2016-10-31
EP2921168B1 (fr)	2016-04-13
TW201206445A (en)	2012-02-16
UY33423A (es)	2011-12-30
PT2404600E (pt)	2015-07-13
AP2013006661A0 (en)	2013-01-31
IL223293A (en)	2017-04-30
ME02476B (me)	2017-02-20
AP2016009002A0 (en)	2016-01-31
BRPI1102830B8 (pt)	2020-01-07
JP5480202B2 (ja)	2014-04-23
SG10201500502WA (en)	2015-03-30
PE20120019A1 (es)	2012-02-11
NI201200182A (es)	2013-05-13
RS54077B1 (sr)	2015-10-30
US20110306598A1 (en)	2011-12-15
HK1210012A1 (en)	2016-04-15
GEP20146132B (en)	2014-08-11
WO2011157908A8 (fr)	2013-01-17
ES2545343T3 (es)	2015-09-10
AU2011202607B2 (en)	2015-02-12
ZA201104222B (en)	2012-02-29
HRP20160643T1 (hr)	2016-07-01
CN104906579A (zh)	2015-09-16
KR20110136752A (ko)	2011-12-21
MX2011006001A (es)	2011-12-14
NZ600931A (en)	2013-04-26
PH12012502315A1 (en)	2013-02-04
CU24161B1 (es)	2016-03-31
EP2921168A1 (fr)	2015-09-23
HUE027788T2 (en)	2016-10-28
BRPI1102830B1 (pt)	2019-10-08
RS54838B1 (sr)	2016-10-31
ECSP12012337A (es)	2012-12-28
DK2921168T3 (en)	2016-08-01
HUE027088T2 (en)	2016-08-29
HRP20150745T1 (hr)	2015-08-14
KR101389879B1 (ko)	2014-04-29
WO2011157908A1 (fr)	2011-12-22
CY1117724T1 (el)	2017-05-17
JO3309B1 (ar)	2018-09-16
DK2404600T3 (en)	2015-08-31
BRPI1102830A2 (pt)	2013-12-24
CN102284060A (zh)	2011-12-21
NZ593437A (en)	2012-08-31
SA114360089B1 (ar)	2016-02-03
PH12012502315B1 (en)	2020-09-18
CA2743527C (fr)	2016-08-02
FR2961105A1 (fr)	2011-12-16
CL2011001420A1 (es)	2012-07-06
EP2404600A1 (fr)	2012-01-11
FR2961105B1 (fr)	2013-02-08
SI2404600T1 (sl)	2015-10-30
AU2011202607A1 (en)	2012-01-12
SG177069A1 (en)	2012-01-30
CU20120166A7 (es)	2013-04-19
ME02163B (me)	2015-10-20
EP2404600B1 (fr)	2015-05-27
IL223293A0 (en)	2013-02-03
EA201100773A1 (ru)	2011-12-30
CO6640265A2 (es)	2013-03-22
CY1116438T1 (el)	2017-02-08
SI2921168T1 (sl)	2016-08-31
TWI468164B (zh)	2015-01-11
UA108983C2 (en)	2015-07-10
EA022612B1 (ru)	2016-02-29
GT201200341A (es)	2014-03-14
PL2404600T3 (pl)	2015-10-30
MY179034A (en)	2020-10-26

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