AP2012006262A0 - Monoclonal antibodies to progastrin and their uses. - Google Patents

Monoclonal antibodies to progastrin and their uses.

Info

Publication number: AP2012006262A0
Authority: AP; ARIPO
Prior art keywords: progastrin; monoclonal antibodies; monoclonal; antibodies
Prior art date: 2009-10-16

Application number

AP2012006262A

Other languages

English (en)

Inventor

Dominique Joubert

Laure Boudier

Julie Pannequin

Original Assignee

Biorealites Inst Nat De La Sante Et De Larech Medicale Inserm

Ct Nat De La Rech Scient Snrs

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-16

Filing date

2010-10-15

Publication date

2012-06-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43086711&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2012006262(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-10-15 Application filed by Biorealites Inst Nat De La Sante Et De Larech Medicale Inserm, Ct Nat De La Rech Scient Snrs filed Critical Biorealites Inst Nat De La Sante Et De Larech Medicale Inserm

2012-06-30 Publication of AP2012006262A0 publication Critical patent/AP2012006262A0/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- G01N33/57535—
- G01N33/57585—
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/595—Gastrins; Cholecystokinins [CCK]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Biomedical Technology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Food Science & Technology (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AP2012006262A 2009-10-16 2010-10-15 Monoclonal antibodies to progastrin and their uses. AP2012006262A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US25262509P	2009-10-16	2009-10-16
PCT/EP2010/006329 WO2011045080A2 (en)	2009-10-16	2010-10-15	Monoclonal antibodies to progastrin and their uses

Publications (1)

Publication Number	Publication Date
AP2012006262A0 true AP2012006262A0 (en)	2012-06-30

Family

ID=43086711

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2012006262A AP2012006262A0 (en)	2009-10-16	2010-10-15	Monoclonal antibodies to progastrin and their uses.

Country Status (42)

Country	Link
US (7)	US9611320B2 (sr)
EP (2)	EP3421493B1 (sr)
JP (3)	JP5985987B2 (sr)
KR (2)	KR20120091221A (sr)
CN (2)	CN102791735B (sr)
AP (1)	AP2012006262A0 (sr)
AR (1)	AR078659A1 (sr)
AU (1)	AU2010306119A1 (sr)
BR (1)	BR112012008818B1 (sr)
CA (1)	CA2777691C (sr)
CL (1)	CL2012000914A1 (sr)
CR (1)	CR20120184A (sr)
CU (1)	CU24196B1 (sr)
CY (1)	CY1120913T1 (sr)
DK (1)	DK2488551T3 (sr)
EA (2)	EA201791876A1 (sr)
EC (1)	ECSP12011796A (sr)
ES (2)	ES2690943T3 (sr)
GE (1)	GEP201706604B (sr)
GT (1)	GT201200114A (sr)
HN (1)	HN2012000708A (sr)
HR (1)	HRP20181645T1 (sr)
IL (2)	IL219019B (sr)
IN (1)	IN2012DN03348A (sr)
LT (1)	LT2488551T (sr)
MA (1)	MA33747B1 (sr)
MX (1)	MX351635B (sr)
NI (1)	NI201200054A (sr)
NZ (2)	NZ599971A (sr)
PE (1)	PE20121649A1 (sr)
PH (1)	PH12012500711B1 (sr)
PL (2)	PL2488551T3 (sr)
PT (1)	PT2488551T (sr)
RS (1)	RS57966B1 (sr)
SG (1)	SG10201704933PA (sr)
SI (1)	SI2488551T1 (sr)
SM (1)	SMT201800628T1 (sr)
TN (1)	TN2012000159A1 (sr)
TW (1)	TWI537002B (sr)
UA (1)	UA106771C2 (sr)
WO (1)	WO2011045080A2 (sr)
ZA (1)	ZA201202642B (sr)

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WO2008076454A1 (en)	2006-12-19	2008-06-26	The Board Of Regents Of The University Of Texas System	Immunogenic compositions comprising progastrin and uses thereof
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MX351635B (es) *	2009-10-16	2017-10-23	Servier Lab	Anticuerpos monoclonales frente a progastrina y sus usos.
US9487582B2 (en) *	2010-01-08	2016-11-08	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Methods for treating pancreatic cancer
US8900817B2 (en) *	2010-01-08	2014-12-02	Les Laboratories Servier	Progastrin and liver pathologies
US20150071912A1 (en) *	2010-03-24	2015-03-12	Centre National De La Recherche Scientifique (Cnrs)	Prophylaxis of colorectal and gastrointestinal cancer
CN103261224B (zh) *	2010-07-26	2015-10-07	瑟维尔实验室	用于肝癌治疗的方法和组合物
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RU2699717C2 (ru) *	2014-04-18	2019-09-09	Дзе Ресёч Фаундэйшен Фор Дзе Штат Юниверсити Ов Нью-Йорк	Гуманизированные антитела к антигену Томсена-Фриденрайха
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BR112019020414A2 (pt) *	2017-03-30	2020-06-09	Progastrine Et Cancers S.À R.L.	composições e métodos para detectar e tratar câncer de próstata usando moléculas de ligação à progastrina
KR102616819B1 (ko) *	2017-03-30	2023-12-21	프로가스트린 에 캔서스 에스.에이 알.엘.	폐암을 치료하기 위한 조성물 및 방법
CA3084687C (en) *	2017-12-05	2024-01-02	Progastrine Et Cancers S.A R.L.	Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
JP7338128B2 (ja)	2017-12-08	2023-09-05	イー、シー、エス、ビオトラッカー、エス、エー、アール、エル	癌診断における放射性標識プロガストリン
TW201940881A (zh)	2018-01-26	2019-10-16	瑞士商Ｅｃｓ前胃泌激素公司	在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
US20200400675A1 (en) *	2018-02-27	2020-12-24	Ecs-Progastrin Sa	Progastrin as a biomarker for immunotherapy
TWI793238B (zh) *	2018-12-27	2023-02-21	偉喬生醫股份有限公司	體外檢測生物樣品之胃源性蛋白的方法及套組
US20220372125A1 (en) *	2019-10-02	2022-11-24	Aslan Pharmaceuticals Pte. Ltd.	Antigen Specific Binding Domains and Antibody Molecules
CN112062846A (zh) *	2020-04-27	2020-12-11	杭州博茵生物技术有限公司	一种g-17单克隆抗体及其应用
CN115785273B (zh) *	2021-09-10	2023-10-31	东莞市朋志生物科技有限公司	一种抗胃蛋白酶原i的抗体及其应用
CN115724949A (zh) *	2022-12-12	2023-03-03	郑州伊美诺生物技术有限公司	一种鼠源lgG单克隆抗体及其制备方法、应用
CN116143920A (zh) *	2022-12-30	2023-05-23	南京岚煜生物科技有限公司	胃泌素17的单克隆抗体及其细胞株的制备方法和应用
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2010
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- 2010-10-15 KR KR1020127012677A patent/KR20120091221A/ko not_active Ceased
- 2010-10-15 CN CN201080057237.3A patent/CN102791735B/zh active Active
- 2010-10-15 NZ NZ599971A patent/NZ599971A/en unknown
- 2010-10-15 DK DK10768878.0T patent/DK2488551T3/en active
- 2010-10-15 PH PH1/2012/500711A patent/PH12012500711B1/en unknown
- 2010-10-15 AP AP2012006262A patent/AP2012006262A0/xx unknown
- 2010-10-15 AR ARP100103784A patent/AR078659A1/es active IP Right Grant
- 2010-10-15 SI SI201031788T patent/SI2488551T1/sl unknown
- 2010-10-15 PE PE2012000434A patent/PE20121649A1/es active IP Right Grant
- 2010-10-15 PL PL10768878T patent/PL2488551T3/pl unknown
- 2010-10-15 EP EP18185172.6A patent/EP3421493B1/en active Active
- 2010-10-15 ES ES10768878.0T patent/ES2690943T3/es active Active
- 2010-10-15 EA EA201791876A patent/EA201791876A1/ru unknown
- 2010-10-15 CA CA2777691A patent/CA2777691C/en active Active
- 2010-10-15 LT LTEP10768878.0T patent/LT2488551T/lt unknown
- 2010-10-15 NZ NZ701709A patent/NZ701709A/en unknown
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- 2010-10-15 GE GEAP201012707A patent/GEP201706604B/en unknown
- 2010-10-15 UA UAA201205759A patent/UA106771C2/uk unknown
- 2010-10-15 US US12/906,041 patent/US9611320B2/en active Active
- 2010-10-15 AU AU2010306119A patent/AU2010306119A1/en not_active Abandoned
- 2010-10-15 SM SM20180628T patent/SMT201800628T1/it unknown
- 2010-10-15 HR HRP20181645TT patent/HRP20181645T1/hr unknown
- 2010-10-15 KR KR1020157017085A patent/KR101640520B1/ko active Active
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- 2010-10-15 PL PL18185172.6T patent/PL3421493T3/pl unknown
- 2010-10-15 WO PCT/EP2010/006329 patent/WO2011045080A2/en not_active Ceased
- 2010-10-15 CN CN201410752851.1A patent/CN104628857A/zh active Pending
- 2010-10-15 PT PT10768878T patent/PT2488551T/pt unknown
- 2010-10-15 EP EP10768878.0A patent/EP2488551B1/en active Active
- 2010-10-15 BR BR112012008818-1A patent/BR112012008818B1/pt active IP Right Grant
- 2010-10-15 RS RS20181241A patent/RS57966B1/sr unknown
- 2010-10-15 JP JP2012533531A patent/JP5985987B2/ja active Active
- 2010-10-15 IN IN3348DEN2012 patent/IN2012DN03348A/en unknown
- 2010-10-15 ES ES18185172T patent/ES2973217T3/es active Active
2012
- 2012-04-03 IL IL219019A patent/IL219019B/en active IP Right Grant
- 2012-04-04 TN TNP2012000159A patent/TN2012000159A1/en unknown
- 2012-04-11 CL CL2012000914A patent/CL2012000914A1/es unknown
- 2012-04-12 ZA ZA2012/02642A patent/ZA201202642B/en unknown
- 2012-04-13 NI NI201200054A patent/NI201200054A/es unknown
- 2012-04-13 EC ECSP12011796 patent/ECSP12011796A/es unknown
- 2012-04-13 CR CR20120184A patent/CR20120184A/es unknown
- 2012-04-13 HN HN2012000708A patent/HN2012000708A/es unknown
- 2012-04-16 GT GT201200114A patent/GT201200114A/es unknown
- 2012-04-16 CU CUP2012000060A patent/CU24196B1/es active IP Right Grant
- 2012-05-11 MA MA34864A patent/MA33747B1/fr unknown
2015
- 2015-03-04 JP JP2015042849A patent/JP6272793B2/ja active Active
2017
- 2017-03-06 US US15/451,268 patent/US10385125B2/en active Active
- 2017-03-06 US US15/451,275 patent/US10377821B2/en active Active
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PL3421493T3 (pl)	2024-04-29
US20180022802A1 (en)	2018-01-25
HK1178183A1 (zh)	2013-09-06
PL2488551T3 (pl)	2019-01-31
JP2017212992A (ja)	2017-12-07
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