NZ315632A - Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water - Google Patents

Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water

Info

Publication number: NZ315632A
Authority: NZ; New Zealand
Prior art keywords: solution; drug; weight; water; carrier particles
Prior art date: 1995-07-29

Application number

NZ315632A

Other languages

English (en)

Inventor

James Albert Napper

Karen Triona O'brien

Sultan James Manek

Rajinder Kumar

Julia Mary Loudon

Michael Sidney George Clark

Neil Mortimer

Original Assignee

Smithkline Beecham Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-29

Filing date

1996-07-29

Publication date

1999-11-29

1995-07-29 Priority claimed from GBGB9515624.6A external-priority patent/GB9515624D0/en

1996-03-29 Priority claimed from GBGB9606684.0A external-priority patent/GB9606684D0/en

1996-07-29 Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc

1999-11-29 Publication of NZ315632A publication Critical patent/NZ315632A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NZ315632A 1995-07-29 1996-07-29 Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water NZ315632A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9515624.6A GB9515624D0 (en)	1995-07-29	1995-07-29	Novel process
GBGB9606684.0A GB9606684D0 (en)	1996-03-29	1996-03-29	Novel process
PCT/EP1996/003326 WO1997004750A2 (en)	1995-07-29	1996-07-29	Process for preparing solid dosage forms of very low-dose drugs

Publications (1)

Publication Number	Publication Date
NZ315632A true NZ315632A (en)	1999-11-29

Family

ID=26307485

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ315632A NZ315632A (en)	1995-07-29	1996-07-29	Process for preparing solid dosage forms of very low-dose drugs comprising admixing 1-3% by weight of carrier particles with a solution of drug in water

Country Status (25)

Country	Link
EP (1)	EP0841902A2 (xx)
JP (1)	JPH11510493A (xx)
KR (1)	KR19990035972A (xx)
CN (1)	CN1196677A (xx)
AP (1)	AP858A (xx)
AR (1)	AR004178A1 (xx)
AU (1)	AU716961B2 (xx)
BG (1)	BG102266A (xx)
BR (1)	BR9609804A (xx)
CA (1)	CA2228048A1 (xx)
CZ (1)	CZ24798A3 (xx)
DZ (1)	DZ2077A1 (xx)
EA (2)	EA199901055A1 (xx)
HU (1)	HUP9900521A3 (xx)
IL (1)	IL122897A0 (xx)
MA (1)	MA23953A1 (xx)
MX (1)	MX9800809A (xx)
NO (1)	NO980384L (xx)
NZ (1)	NZ315632A (xx)
OA (1)	OA10659A (xx)
PL (1)	PL325242A1 (xx)
SK (1)	SK11098A3 (xx)
TR (1)	TR199800156T1 (xx)
UY (1)	UY24297A1 (xx)
WO (1)	WO1997004750A2 (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9619074D0 (en) *	1996-09-12	1996-10-23	Smithkline Beecham Plc	Composition
KR20010034588A (ko) *	1998-03-11	2001-04-25	피터 기딩스	조성물
FR2796840B1 (fr) *	1999-07-26	2003-06-20	Ethypharm Lab Prod Ethiques	Comprimes faiblement doses et procede de preparation
CZ306435B6 (cs)	2000-12-14	2017-01-25	Ortho-Mcneil Pharmaceutical, Inc.	Steroidní hormonální přípravek a způsob jeho přípravy
US20070202179A1 (en) *	2004-04-09	2007-08-30	FAULKNER Patrick	Low Dose Pharmaceutical Products
WO2026018155A1 (en)	2024-07-16	2026-01-22	Syremis Therapeutics Ltd.	Combinations of sabcomeline with long-acting non-cns penetrant muscarinic antagonists
WO2026018154A1 (en)	2024-07-16	2026-01-22	Syremis Therapeutics Ltd.	Combinations of sabcomeline with non-cns penetrant muscarinic antagonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4489026A (en) *	1982-09-07	1984-12-18	The Upjohn Company	Process for preparing solid unit dosage forms of ultra-low dose drugs
JPS5970614A (ja) *	1982-10-14	1984-04-21	Asahi Chem Ind Co Ltd	微量主薬系湿式固形製剤方法
US4898736A (en) *	1988-03-09	1990-02-06	Merck & Co., Inc.	Method for tablet preparation
DE69034146T2 (de) *	1989-04-13	2005-07-14	Beecham Group P.L.C., Brentford	Chemische Verbindungen
ZA939565B (en) *	1993-12-21	1994-08-11	Applied Analytical Ind Inc	Method for preparing low dose pharmaceutical products.

1996
- 1996-07-25 AR ARP960103748A patent/AR004178A1/es not_active Application Discontinuation
- 1996-07-26 UY UY24297A patent/UY24297A1/es not_active IP Right Cessation
- 1996-07-26 MA MA24329A patent/MA23953A1/fr unknown
- 1996-07-27 DZ DZ960121A patent/DZ2077A1/fr active
- 1996-07-29 JP JP9507243A patent/JPH11510493A/ja active Pending
- 1996-07-29 IL IL12289796A patent/IL122897A0/xx unknown
- 1996-07-29 BR BR9609804A patent/BR9609804A/pt not_active Application Discontinuation
- 1996-07-29 AU AU67384/96A patent/AU716961B2/en not_active Ceased
- 1996-07-29 KR KR1019980700633A patent/KR19990035972A/ko not_active Ceased
- 1996-07-29 CA CA002228048A patent/CA2228048A1/en not_active Abandoned
- 1996-07-29 EA EA199901055A patent/EA199901055A1/ru unknown
- 1996-07-29 CN CN96197054A patent/CN1196677A/zh active Pending
- 1996-07-29 EP EP96927621A patent/EP0841902A2/en not_active Withdrawn
- 1996-07-29 SK SK110-98A patent/SK11098A3/sk unknown
- 1996-07-29 WO PCT/EP1996/003326 patent/WO1997004750A2/en not_active Ceased
- 1996-07-29 CZ CZ98247A patent/CZ24798A3/cs unknown
- 1996-07-29 HU HU9900521A patent/HUP9900521A3/hu unknown
- 1996-07-29 NZ NZ315632A patent/NZ315632A/xx unknown
- 1996-07-29 MX MX9800809A patent/MX9800809A/es unknown
- 1996-07-29 TR TR1998/00156T patent/TR199800156T1/xx unknown
- 1996-07-29 AP APAP/P/1998/001170A patent/AP858A/en active
- 1996-07-29 PL PL96325242A patent/PL325242A1/xx unknown
- 1996-07-29 EA EA199800179A patent/EA000740B1/ru not_active IP Right Cessation
1998
- 1998-01-28 NO NO980384A patent/NO980384L/no unknown
- 1998-01-28 OA OA9800013A patent/OA10659A/en unknown
- 1998-02-20 BG BG102266A patent/BG102266A/xx unknown

Also Published As

Publication number	Publication date
NO980384D0 (no)	1998-01-28
AR004178A1 (es)	1998-11-04
MX9800809A (es)	1998-04-30
EA199901055A1 (ru)	2000-06-26
CZ24798A3 (cs)	1998-06-17
EP0841902A2 (en)	1998-05-20
DZ2077A1 (fr)	2002-07-22
BR9609804A (pt)	1999-07-06
AP9801170A0 (en)	1998-01-31
JPH11510493A (ja)	1999-09-14
PL325242A1 (en)	1998-07-06
UY24297A1 (es)	1997-01-23
SK11098A3 (en)	1998-07-08
EA199800179A1 (ru)	1998-10-29
CN1196677A (zh)	1998-10-21
KR19990035972A (ko)	1999-05-25
TR199800156T1 (xx)	1998-04-21
CA2228048A1 (en)	1997-02-13
AU6738496A (en)	1997-02-26
NO980384L (no)	1998-03-26
EA000740B1 (ru)	2000-02-28
WO1997004750A3 (en)	1997-03-27
HUP9900521A2 (hu)	1999-06-28
HUP9900521A3 (en)	2001-04-28
WO1997004750A2 (en)	1997-02-13
OA10659A (en)	2002-09-18
AU716961B2 (en)	2000-03-09
AP858A (en)	2000-07-12
BG102266A (en)	1998-10-30
MA23953A1 (fr)	1997-04-01
IL122897A0 (en)	1998-08-16

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