NO991234L - Trisykliske inhibitorer av farnesylproteintransferase - Google Patents
Trisykliske inhibitorer av farnesylproteintransferaseInfo
- Publication number
- NO991234L NO991234L NO991234A NO991234A NO991234L NO 991234 L NO991234 L NO 991234L NO 991234 A NO991234 A NO 991234A NO 991234 A NO991234 A NO 991234A NO 991234 L NO991234 L NO 991234L
- Authority
- NO
- Norway
- Prior art keywords
- protein transferase
- farnesyl protein
- tricyclic inhibitors
- formula
- compounds
- Prior art date
Links
- 102000004357 Transferases Human genes 0.000 title abstract 2
- 108090000992 Transferases Proteins 0.000 title abstract 2
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
- Cereal-Derived Products (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71332396A | 1996-09-13 | 1996-09-13 | |
| PCT/US1997/015907 WO1998011093A1 (en) | 1996-09-13 | 1997-09-11 | Tricyclic inhibitors of farnesyl protein transferase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO991234D0 NO991234D0 (no) | 1999-03-12 |
| NO991234L true NO991234L (no) | 1999-05-12 |
Family
ID=24865689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO991234A NO991234L (no) | 1996-09-13 | 1999-03-12 | Trisykliske inhibitorer av farnesylproteintransferase |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0929545B1 (pt) |
| JP (1) | JP2001500510A (pt) |
| KR (1) | KR20000036120A (pt) |
| CN (1) | CN1104427C (pt) |
| AT (1) | ATE286046T1 (pt) |
| AU (1) | AU4337997A (pt) |
| BR (1) | BR9712831A (pt) |
| CA (1) | CA2266016C (pt) |
| CZ (1) | CZ84399A3 (pt) |
| DE (1) | DE69732120T2 (pt) |
| ES (1) | ES2235252T3 (pt) |
| HU (1) | HUP0000121A2 (pt) |
| ID (1) | ID21699A (pt) |
| IL (1) | IL128928A0 (pt) |
| NO (1) | NO991234L (pt) |
| NZ (1) | NZ334453A (pt) |
| PL (1) | PL332242A1 (pt) |
| SK (1) | SK33899A3 (pt) |
| TR (1) | TR199901276T2 (pt) |
| WO (1) | WO1998011093A1 (pt) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT3962B (en) | 1993-12-21 | 1996-05-27 | Albright & Wilson | Funcional fluids |
| US5939416A (en) * | 1997-06-17 | 1999-08-17 | Schering Corporation | Benzo (5,6) cycloheptapyridine compounds useful as farnesyl protein transferase inhibitors |
| AU2335699A (en) | 1998-01-21 | 1999-08-09 | Kyowa Hakko Kogyo Co. Ltd. | Chemokine receptor antagonists and methods of use therefor |
| EP1049700B9 (en) | 1998-01-21 | 2006-05-10 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6509346B2 (en) | 1998-01-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6613905B1 (en) | 1998-01-21 | 2003-09-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6503926B2 (en) | 1998-09-04 | 2003-01-07 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US6288083B1 (en) | 1998-09-04 | 2001-09-11 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| US7271176B2 (en) | 1998-09-04 | 2007-09-18 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use thereof |
| US7541365B2 (en) | 2001-11-21 | 2009-06-02 | Millennium Pharmaceuticals, Inc. | Chemokine receptor antagonists and methods of use therefor |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
| US9579088B2 (en) | 2007-02-20 | 2017-02-28 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices for surgical visualization and device manipulation |
| US8679096B2 (en) | 2007-06-21 | 2014-03-25 | Board Of Regents Of The University Of Nebraska | Multifunctional operational component for robotic devices |
| TW200902007A (en) * | 2007-05-25 | 2009-01-16 | Astrazeneca Ab | Spirocyclopropyl piperidine derivatives |
| EP3078344B1 (en) | 2007-07-12 | 2020-02-26 | Board of Regents of the University of Nebraska | Actuation in robotic devices |
| CA2695615A1 (en) | 2007-08-15 | 2009-02-19 | Board Of Regents Of The University Of Nebraska | Medical inflation, attachment, and delivery devices and related methods |
| CA2838637C (en) | 2011-06-10 | 2020-11-17 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to surgical end effectors |
| JP6106169B2 (ja) | 2011-07-11 | 2017-03-29 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | 手術ロボットシステム |
| EP2882330B1 (en) | 2011-10-03 | 2020-05-13 | Board of Regents of the University of Nebraska | Robotic surgical devices and systems |
| US10582973B2 (en) | 2012-08-08 | 2020-03-10 | Virtual Incision Corporation | Robotic surgical devices, systems, and related methods |
| EP3970784A1 (en) | 2012-01-10 | 2022-03-23 | Board of Regents of the University of Nebraska | Systems and devices for surgical access and insertion |
| CA2871149C (en) | 2012-05-01 | 2020-08-25 | Board Of Regents Of The University Of Nebraska | Single site robotic device and related systems and methods |
| JP6228196B2 (ja) | 2012-06-22 | 2017-11-08 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | ローカル制御ロボット手術デバイス |
| US9770305B2 (en) | 2012-08-08 | 2017-09-26 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems, and related methods |
| US9743987B2 (en) | 2013-03-14 | 2017-08-29 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to robotic surgical devices, end effectors, and controllers |
| US9888966B2 (en) | 2013-03-14 | 2018-02-13 | Board Of Regents Of The University Of Nebraska | Methods, systems, and devices relating to force control surgical systems |
| CA2906772C (en) | 2013-03-15 | 2021-09-21 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems and related methods |
| CA2918531A1 (en) | 2013-07-17 | 2015-01-22 | Board Of Regents Of The University Of Nebraska | Robotic surgical devices, systems and related methods |
| US10342561B2 (en) | 2014-09-12 | 2019-07-09 | Board Of Regents Of The University Of Nebraska | Quick-release end effectors and related systems and methods |
| WO2016077478A1 (en) | 2014-11-11 | 2016-05-19 | Board Of Regents Of The University Of Nebraska | Robotic device with compact joint design and related systems and methods |
| EP4555965A3 (en) | 2015-08-03 | 2025-07-02 | Virtual Incision Corporation | Robotic surgical devices, systems and related methods |
| JP7176757B2 (ja) | 2016-05-18 | 2022-11-22 | バーチャル インシジョン コーポレイション | ロボット手術装置、システム及び関連する方法 |
| WO2018039606A1 (en) | 2016-08-25 | 2018-03-01 | Virtual Incision Corporation | Quick-release tool coupler and related systems and methods |
| JP7090615B2 (ja) | 2016-08-30 | 2022-06-24 | ボード オブ リージェンツ オブ ザ ユニバーシティ オブ ネブラスカ | ロボットデバイス |
| CN115337111B (zh) | 2016-11-22 | 2025-04-25 | 内布拉斯加大学董事会 | 改进的粗定位装置及相关系统和方法 |
| CN110462259B (zh) | 2016-11-29 | 2022-10-28 | 虚拟切割有限公司 | 具有用户存在检测的用户控制器及相关系统和方法 |
| US10722319B2 (en) | 2016-12-14 | 2020-07-28 | Virtual Incision Corporation | Releasable attachment device for coupling to medical devices and related systems and methods |
| US11051894B2 (en) | 2017-09-27 | 2021-07-06 | Virtual Incision Corporation | Robotic surgical devices with tracking camera technology and related systems and methods |
| CN117140580A (zh) | 2018-01-05 | 2023-12-01 | 内布拉斯加大学董事会 | 具有紧凑型关节设计的单臂机器人装置及相关系统和方法 |
| US11903658B2 (en) | 2019-01-07 | 2024-02-20 | Virtual Incision Corporation | Robotically assisted surgical system and related devices and methods |
| CA3186863A1 (en) | 2020-07-06 | 2022-01-13 | Virtual Incision Corporation | Surgical robot positioning system and related devices and methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| US4826853A (en) * | 1986-10-31 | 1989-05-02 | Schering Corporation | 6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use |
| KR920014799A (ko) * | 1991-01-18 | 1992-08-25 | 나오가따 다이도 | 신규벤조[5,6]시클로헵타[1,2-b]피리딘 유도체 및 이를 함유하는 항알레르기제 |
| HUT76066A (en) * | 1993-10-15 | 1997-06-30 | Schering Corp | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases, pharmaceutical compositions containing them and process for producing them |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
| NZ275646A (en) * | 1993-10-15 | 1998-02-26 | Schering Corp | Tricyclic sulphonamide derivatives and medicaments |
| US5700806A (en) * | 1995-03-24 | 1997-12-23 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases |
| IL117798A (en) * | 1995-04-07 | 2001-11-25 | Schering Plough Corp | Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them |
| WO1997023478A1 (en) * | 1995-12-22 | 1997-07-03 | Schering Corporation | Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases |
-
1997
- 1997-09-11 AU AU43379/97A patent/AU4337997A/en not_active Abandoned
- 1997-09-11 CZ CZ99843A patent/CZ84399A3/cs unknown
- 1997-09-11 KR KR1019997002149A patent/KR20000036120A/ko not_active Withdrawn
- 1997-09-11 JP JP10513765A patent/JP2001500510A/ja not_active Ceased
- 1997-09-11 NZ NZ334453A patent/NZ334453A/xx unknown
- 1997-09-11 HU HU0000121A patent/HUP0000121A2/hu unknown
- 1997-09-11 TR TR1999/01276T patent/TR199901276T2/xx unknown
- 1997-09-11 PL PL97332242A patent/PL332242A1/xx unknown
- 1997-09-11 BR BR9712831-7A patent/BR9712831A/pt unknown
- 1997-09-11 DE DE69732120T patent/DE69732120T2/de not_active Expired - Fee Related
- 1997-09-11 EP EP97941480A patent/EP0929545B1/en not_active Expired - Lifetime
- 1997-09-11 CN CN97199598A patent/CN1104427C/zh not_active Expired - Fee Related
- 1997-09-11 SK SK338-99A patent/SK33899A3/sk unknown
- 1997-09-11 ES ES97941480T patent/ES2235252T3/es not_active Expired - Lifetime
- 1997-09-11 AT AT97941480T patent/ATE286046T1/de not_active IP Right Cessation
- 1997-09-11 WO PCT/US1997/015907 patent/WO1998011093A1/en not_active Ceased
- 1997-09-11 IL IL12892897A patent/IL128928A0/xx unknown
- 1997-09-11 CA CA002266016A patent/CA2266016C/en not_active Expired - Fee Related
- 1997-11-09 ID IDW990086A patent/ID21699A/id unknown
-
1999
- 1999-03-12 NO NO991234A patent/NO991234L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0929545B1 (en) | 2004-12-29 |
| CA2266016A1 (en) | 1998-03-19 |
| TR199901276T2 (xx) | 1999-09-21 |
| EP0929545A1 (en) | 1999-07-21 |
| SK33899A3 (en) | 2000-02-14 |
| HUP0000121A2 (hu) | 2001-04-28 |
| JP2001500510A (ja) | 2001-01-16 |
| BR9712831A (pt) | 1999-11-16 |
| ATE286046T1 (de) | 2005-01-15 |
| CN1104427C (zh) | 2003-04-02 |
| CZ84399A3 (cs) | 1999-11-17 |
| ES2235252T3 (es) | 2005-07-01 |
| NZ334453A (en) | 2000-08-25 |
| IL128928A0 (en) | 2000-02-17 |
| ID21699A (id) | 1999-07-15 |
| KR20000036120A (ko) | 2000-06-26 |
| DE69732120T2 (de) | 2005-12-08 |
| NO991234D0 (no) | 1999-03-12 |
| CN1237165A (zh) | 1999-12-01 |
| CA2266016C (en) | 2004-06-01 |
| WO1998011093A1 (en) | 1998-03-19 |
| DE69732120D1 (de) | 2005-02-03 |
| PL332242A1 (en) | 1999-08-30 |
| AU4337997A (en) | 1998-04-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO991234L (no) | Trisykliske inhibitorer av farnesylproteintransferase | |
| NO991229L (no) | Substituerte benzosykloheptapyridinderivater for inhibering av farnesylproteintransferase | |
| NO991235D0 (no) | Forbindelser anvendelige for inhibering av farnesylproteintransferase | |
| NO991231L (no) | Forbindelser for inhibering av farnesylproteintransferase | |
| NO991232L (no) | Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase | |
| IL133392A0 (en) | Benzo (5, 6) cyclohepta (1, 2b) pyridine derivatives useful for inhibition of farnesyl protein transferase | |
| TR200000114T2 (tr) | Farnesil protein transferazı'nın önlenmesine mahsus benzo(5,6)siklohepta(1,2-B)piridin türevleri. | |
| AU1847401A (en) | Diketopiperazine derivatives to inhibit thrombin | |
| CA2293713A1 (en) | Bispyrido-cycloheptane compounds useful for inhibition of farnesyl protein transferase |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |