NO990951L - Sykliske aminderivater - Google Patents

Sykliske aminderivater

Info

Publication number: NO990951L
Authority: NO; Norway
Prior art keywords: alkoxy; alkyl; substituted; optionally substituted; halo
Prior art date: 1996-08-28

Application number

NO990951A

Other languages

English (en)

Other versions

NO990951D0 (no

NO312955B1 (no

Inventor

Fumitosho Asai

Atsuhiro Sugidachi

Toshihiko Ikeda

Hiroyuki Koike

Teruhiko Inoue

Katsunori Takata

Ryo Iwamura

Jun-Ichiro Kita

Kenji Yoneda

Original Assignee

Sankyo Co

Ube Industries

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-28

Filing date

1999-02-26

Publication date

1999-04-27

1999-02-26 Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co

1999-02-26 Publication of NO990951D0 publication Critical patent/NO990951D0/no

1999-04-27 Publication of NO990951L publication Critical patent/NO990951L/no

2002-07-22 Publication of NO312955B1 publication Critical patent/NO312955B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO19990951A 1996-08-28 1999-02-26 Sykliske aminderivater, farmasöytisk preparat og anvendelse av derivatene for fremstilling av et medikament NO312955B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP22650796		1996-08-28
PCT/JP1997/002990 WO1998008811A1 (en)	1996-08-28	1997-08-28	Cyclic amine derivatives

Publications (3)

Publication Number	Publication Date
NO990951D0 NO990951D0 (no)	1999-02-26
NO990951L true NO990951L (no)	1999-04-27
NO312955B1 NO312955B1 (no)	2002-07-22

Family

ID=16846212

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19990951A NO312955B1 (no)	1996-08-28	1999-02-26	Sykliske aminderivater, farmasöytisk preparat og anvendelse av derivatene for fremstilling av et medikament

Country Status (17)

Country	Link
US (1)	US6087379A (no)
EP (1)	EP0934928B1 (no)
KR (1)	KR100417887B1 (no)
CN (1)	CN1192019C (no)
AT (1)	ATE279389T1 (no)
AU (1)	AU715531B2 (no)
CA (1)	CA2263983C (no)
CZ (1)	CZ300295B6 (no)
DE (1)	DE69731218T2 (no)
ES (1)	ES2229382T3 (no)
HU (1)	HU228082B1 (no)
IL (1)	IL128690A (no)
NO (1)	NO312955B1 (no)
NZ (1)	NZ334389A (no)
PT (1)	PT934928E (no)
RU (1)	RU2163596C2 (no)
WO (1)	WO1998008811A1 (no)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100567950B1 (ko) *	1998-02-27	2006-04-05	상꾜 가부시키가이샤	환상 아미노화합물
ATE348798T1 (de) *	2000-06-08	2007-01-15	Kaneka Corp	Verfahren zur herstellung von sulfonsäureestern
RU2300521C2 (ru) *	2000-12-01	2007-06-10	Астразенека Аб	Новые производные миндальной кислоты и их применение в качестве ингибиторов тромбина
EP1695962A4 (en) *	2003-11-28	2007-03-28	Sankyo Co	CYCLIC AMINE DERIVATIVE WITH HETEROARYLRING
WO2006002350A1 (en) *	2004-06-24	2006-01-05	Incyte Corporation	Amido compounds and their use as pharmaceuticals
WO2006012226A2 (en)	2004-06-24	2006-02-02	Incyte Corporation	N-substituted piperidines and their use as pharmaceuticals
US20090306059A1 (en) *	2005-05-13	2009-12-10	Tomio Kimura	Cyclic amine derivative having substituted alkyl group
AU2006250335B2 (en) *	2005-05-27	2010-09-02	Daiichi Sankyo Company, Limited	Cyclic amine derivative having substituted alkyl group
WO2007024472A2 (en) *	2005-08-19	2007-03-01	Eli Lilly And Company	USE OF PAR- l/PAR- 4 INHIBITORS FOR TREATING OR PREVENTING VASCULAR DISEASES
KR101044559B1 (ko) *	2007-09-20	2011-06-28	국제약품공업주식회사	티올 화합물의 산부가염 및 그의 제조방법
WO2010114181A1 (en) *	2009-04-02	2010-10-07	Shionogi & Co., Ltd.	Acrylamide compounds and the use thereof
DE202009018503U1 (de)	2009-04-30	2011-11-16	Saint-Gobain Sekurit Deutschland Gmbh & Co. Kg	Infrarotstrahlung abschirmendes, für sichtbares Licht transparentes Laminat mit einem für Infrarotstrahlung durchlässigen optischen Fenster
WO2013024376A1 (en) *	2011-08-16	2013-02-21	Mahesh Kandula	Compositions and methods for the treatment of atherothrombosis
WO2014037832A2 (en)	2012-09-06	2014-03-13	Mahesh Kandula	Compositions and methods for the treatment of epilepsy and neurological diseases
WO2013168021A1 (en)	2012-05-07	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of neuromuscular disorders and neurodegenerative disorders
WO2013167990A1 (en)	2012-05-07	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of depression
EP2847169A4 (en)	2012-05-07	2015-09-30	Cellix Bio Private Ltd	COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS
WO2013168025A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of blood clotting disorders
US9403826B2 (en)	2012-05-08	2016-08-02	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammatory disorders
WO2013167991A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of metabolic disorders
WO2013167993A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurological degenerative disorders
WO2013168023A1 (en)	2012-05-08	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of parkinson's disease
US9315478B2 (en)	2012-05-10	2016-04-19	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
WO2013168012A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of respiratory disorders
US9394288B2 (en)	2012-05-10	2016-07-19	Cellix Bio Private Limited	Compositions and methods for the treatment of asthma and allergy
US9315461B2 (en)	2012-05-10	2016-04-19	Cellix Bio Private Limited	Compositions and methods for the treatment of neurologic diseases
US9339484B2 (en)	2012-05-10	2016-05-17	Cellix Bio Private Limited	Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
WO2013168002A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of neurological conditions
WO2013168014A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of familial amyloid polyneuropathy
US9346742B2 (en)	2012-05-10	2016-05-24	Cellix Bio Private Limited	Compositions and methods for the treatment of fibromyalgia pain
WO2013168033A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for treatment of neurologic diseases
WO2013168016A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of metabolic syndrome
US9321775B2 (en)	2012-05-10	2016-04-26	Cellix Bio Private Limited	Compositions and methods for the treatment of moderate to severe pain
WO2013168011A1 (en)	2012-05-10	2013-11-14	Mahesh Kandula	Compositions and methods for the treatment of chronic pain
US9573927B2 (en)	2012-05-10	2017-02-21	Cellix Bio Private Limited	Compositions and methods for the treatment of severe pain
CA2873098A1 (en)	2012-05-23	2013-11-28	Cellixbio Private Limited	Compositions and methods for the treatment of multiple sclerosis
US9434729B2 (en)	2012-05-23	2016-09-06	Cellix Bio Private Limited	Compositions and methods for the treatment of periodontitis and rheumatoid arthritis
WO2013175347A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of respiratory disorders
WO2013175376A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of local pain
WO2013175377A2 (en)	2012-05-23	2013-11-28	Mahesh Kandula	Compositions and methods for the treatment of mucositis
AU2013264894B2 (en)	2012-05-23	2015-11-19	Cellix Bio Private Limited	Compositions and methods for treatment of inflammatory bowel disease
US9108942B1 (en)	2014-11-05	2015-08-18	Mahesh Kandula	Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (en)	2012-08-03	2014-02-06	Mahesh Kandula	Compositions and methods for the treatment migraine and neurologic diseases
WO2014037833A2 (en)	2012-09-06	2014-03-13	Mahesh Kandula	Compositions and methods for the treatment inflammation and lipid disorders
AU2013311349A1 (en)	2012-09-08	2014-11-27	Cellixbio Private Limited	Compositions and methods for treatment of inflammation and lipid disorders
WO2014118649A2 (en) *	2013-01-19	2014-08-07	Mahesh Kandula	Compositions and methods for the treatment of cardiovascular diseases
US9333187B1 (en)	2013-05-15	2016-05-10	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammatory bowel disease
EP3004049B1 (en)	2013-06-04	2018-09-05	Cellixbio Private Limited	Compositions and methods for the treatment of diabetes and pre-diabetes
US9096537B1 (en)	2014-12-31	2015-08-04	Mahesh Kandula	Compositions and methods for the treatment of mucositis
WO2016110865A1 (en)	2015-01-06	2016-07-14	Cellix Bio Private Limited	Compositions and methods for the treatment of inflammation and pain
SG11201706952VA (en)	2014-09-26	2017-10-30	Cellix Bio Private Ltd	Compositions and methods for the treatment of epilepsy and neurological disorders
ES2799309T3 (es)	2014-09-29	2020-12-16	Cellix Bio Private Ltd	Compuestos y composiciones para el tratamiento de esclerosis múltiple
SG11201703369WA (en)	2014-10-27	2017-05-30	Cellix Bio Private Ltd	Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis
US9284287B1 (en)	2014-11-05	2016-03-15	Cellix Bio Private Limited	Compositions and methods for the suppression of carbonic anhydrase activity
US9150557B1 (en)	2014-11-05	2015-10-06	Cellix Bio Private Limited	Compositions and methods for the treatment of hyperglycemia
US9290486B1 (en)	2014-11-05	2016-03-22	Cellix Bio Private Limited	Compositions and methods for the treatment of epilepsy
US9173877B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Compositions and methods for the treatment of local pain
US10208014B2 (en)	2014-11-05	2019-02-19	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological disorders
US9321716B1 (en)	2014-11-05	2016-04-26	Cellix Bio Private Limited	Compositions and methods for the treatment of metabolic syndrome
US9175008B1 (en)	2014-11-05	2015-11-03	Cellix Bio Private Limited	Prodrugs of anti-platelet agents
US9932294B2 (en)	2014-12-01	2018-04-03	Cellix Bio Private Limited	Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en)	2014-12-17	2015-12-08	Cellix Bio Private Limited	Compositions and methods for the treatment of neurological diseases
CN106554302A (zh) *	2015-09-25	2017-04-05	陕西合成药业股份有限公司	噻吩并吡啶类衍生物及其制备方法和用途
CN106554303A (zh) *	2015-09-25	2017-04-05	陕西合成药业股份有限公司	噻吩并吡啶类衍生物及其制备方法和用途
CN106554368A (zh) *	2015-09-25	2017-04-05	陕西合成药业股份有限公司	噻吩并吡啶类衍生物及其制备方法和用途
CN105481760A (zh) *	2016-01-20	2016-04-13	天津药物研究院有限公司	衍生化的替比格雷活性代谢产物的制备方法
CN111484446A (zh) *	2020-04-02	2020-08-04	北京翼方生物科技有限责任公司	氯吡格雷代谢活性体二硫衍生物、其制备方法及医药用途
KR102906376B1 (ko) *	2020-07-29	2025-12-30	상하이 큐어진 파마슈티컬 컴퍼니 리미티드	항혈소판 약물 및 이의 용도
WO2025108300A1 (zh) *	2023-11-24	2025-05-30	上海柯君医药科技有限公司	一种含哌啶环化合物的苯磺酸盐的晶型、其制备方法及应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2215948B1 (no) *	1973-02-01	1976-05-14	Centre Etd Ind Pharma
FR2495156A1 (fr) *	1980-11-28	1982-06-04	Sanofi Sa	Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique
FR2530247B1 (fr) *	1982-07-13	1986-05-16	Sanofi Sa	Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique
FR2576901B1 (fr) *	1985-01-31	1987-03-20	Sanofi Sa	Nouveaux derives de l'acide a-(oxo-2 hexahydro-2,4,5,6,7,7a thieno (3,2-c) pyridyl-5) phenyl acetique, leur procede de preparation et leur application therapeutique
FR2623810B2 (fr) *	1987-02-17	1992-01-24	Sanofi Sa	Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
IT1245712B (it) *	1991-04-09	1994-10-14	Boehringer Mannheim Italia	Ammine eterocicliche utili terapia dell'asma e dell'infiammazione delle vie aeree
JPH04334358A (ja) *	1991-05-02	1992-11-20	Ono Pharmaceut Co Ltd	縮合ベンゼンオキシ酢酸誘導体
FI101150B (fi) *	1991-09-09	1998-04-30	Sankyo Co	Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi
JPH07503459A (ja) *	1992-01-21	1995-04-13	グラクソ、グループ、リミテッド	酢酸誘導体
EP0621037B1 (de) *	1993-04-23	1999-07-07	Hoechst Aktiengesellschaft	Pyrido-pyrimidindione, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
EP1393723A3 (en) *	1993-09-17	2004-10-20	The Brigham And Women's Hospital, Inc.	Use of nitric oxide-adducts to prevent thrombosis on artificial and vascular surfaces

1997
- 1997-07-28 NZ NZ334389A patent/NZ334389A/en not_active IP Right Cessation
- 1997-08-28 KR KR10-1999-7001526A patent/KR100417887B1/ko not_active Expired - Lifetime
- 1997-08-28 AU AU40312/97A patent/AU715531B2/en not_active Expired
- 1997-08-28 CZ CZ0063099A patent/CZ300295B6/cs not_active IP Right Cessation
- 1997-08-28 CA CA002263983A patent/CA2263983C/en not_active Expired - Lifetime
- 1997-08-28 PT PT97937814T patent/PT934928E/pt unknown
- 1997-08-28 CN CNB971992452A patent/CN1192019C/zh not_active Expired - Lifetime
- 1997-08-28 IL IL12869097A patent/IL128690A/xx not_active IP Right Cessation
- 1997-08-28 RU RU99104152/04A patent/RU2163596C2/ru active
- 1997-08-28 HU HU9903762A patent/HU228082B1/hu not_active IP Right Cessation
- 1997-08-28 AT AT97937814T patent/ATE279389T1/de active
- 1997-08-28 DE DE69731218T patent/DE69731218T2/de not_active Expired - Lifetime
- 1997-08-28 WO PCT/JP1997/002990 patent/WO1998008811A1/ja not_active Ceased
- 1997-08-28 EP EP97937814A patent/EP0934928B1/en not_active Expired - Lifetime
- 1997-08-28 ES ES97937814T patent/ES2229382T3/es not_active Expired - Lifetime
1999
- 1999-02-25 US US09/257,818 patent/US6087379A/en not_active Expired - Lifetime
- 1999-02-26 NO NO19990951A patent/NO312955B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU228082B1 (en)	2012-10-29
ATE279389T1 (de)	2004-10-15
KR100417887B1 (ko)	2004-02-11
CZ300295B6 (cs)	2009-04-15
CA2263983C (en)	2006-03-21
NO990951D0 (no)	1999-02-26
US6087379A (en)	2000-07-11
EP0934928A1 (en)	1999-08-11
DE69731218T2 (de)	2005-06-30
CN1192019C (zh)	2005-03-09
IL128690A (en)	2003-03-12
CN1235596A (zh)	1999-11-17
DE69731218D1 (de)	2004-11-18
HUP9903762A2 (hu)	2000-02-28
PT934928E (pt)	2004-12-31
KR20000035839A (ko)	2000-06-26
NO312955B1 (no)	2002-07-22
WO1998008811A1 (en)	1998-03-05
HUP9903762A3 (en)	2001-02-28
RU2163596C2 (ru)	2001-02-27
EP0934928A4 (en)	2001-05-09
NZ334389A (en)	2001-05-25
CA2263983A1 (en)	1998-03-05
ES2229382T3 (es)	2005-04-16
AU715531B2 (en)	2000-02-03
AU4031297A (en)	1998-03-19
CZ63099A3 (cs)	1999-07-14
IL128690A0 (en)	2000-01-31
EP0934928B1 (en)	2004-10-13

Publication	Publication Date	Title
DE69731218D1 (de)	2004-11-18	Zyklische aminderivate
DE69628466D1 (de)	2003-07-03	Zwischenverbindungen zur Herstellung von neunen Pyridoncarbonsäurederivate oder deren Salzen
DE69420564D1 (de)	1999-10-14	Immunsuppressive und antiallergische verbindungen; z.b. n-(3-oxohexanoyl)-homoserinlacton
DK0759295T3 (da)	1999-01-25	Anvendelse af adamantan-derivater til behandling af tinnitus
EA200200661A1 (ru)	2003-02-27	3-аминохиназолин-2,4-дионовые антибактериальные агенты
TW348178B (en)	1998-12-21	Octacyclodepsipeptides having an action for killing endoparasites in animals
FI970246A7 (fi)	1997-01-21	Dihydrobentsofuraanit
PL295030A1 (en)	1993-05-31	Method of obtaining substituted derivatives of 2-cyclohexan-1-yl amine
ATE222115T1 (de)	2002-08-15	Verbesserung der antibakteriellen wirkung von oxazolidinon durch arginin derivate
DK0932597T3 (da)	2002-06-24	Anvendelse af gamma-hydroxysmørsyreamider til behandling af lægemiddelafhængighed og især alkoholisme
AR012489A1 (es)	2000-10-18	Tiofenopiridinas antagonistas del factor de liberacion de corticotropina. procedimiento para su preparacion, el uso de las mismas en la preparacionde un medicamento, composicion farmaceutica que las comprende, procedimiento para la preparacion de dicha composicion, un compuesto intermediario y
DE69207194D1 (de)	1996-02-08	Verfahren zur Herstellung von Bacchatin III und von Desacetyl-10-Bacchatin III Derivate
TR200102129T2 (tr)	2002-01-21	Karbamat ve karbazat ketolid antibiyotikleri.
DK0686142T3 (da)	1999-08-30	Polyaminderivater som radioprotektive midler
ES555992A0 (es)	1987-05-01	Procedimiento para la obtencion de e-isomeros de derivados y peptidos de n<-(2-ciano-2-alcoximino-acetil)-aminoacidos
DE59400211D1 (de)	1996-05-23	Fungizide Mischungen
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
HUP9902992A3 (en)	2004-04-28	Alpha-amino acid amides, preparation thereof and pharmaceutical compositions containing them
NO972943L (no)	1997-12-29	4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende dem og deres anvendelse
ATE216392T1 (de)	2002-05-15	7-oxo-2,3,7,14-tetrahydro-1h-benzo(b)pyrano(3,2 h)acridincarboxylatderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DK0985665T3 (da)	2003-03-17	Fremgangsmåde til fremstilling af 3-amino-2-oxo-pyrrolidiner, mellemprodukter og anvendelse af disse
DE69702955D1 (de)	2000-10-05	Bis-Imide Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitung
TW429147B (en)	2001-04-11	Pharmaceutical composition for the treatment of CNS disorders
MXPA04011363A (es)	2005-02-14	Nuevos derivados acil hidrazino del tiofeno, su procedimiento de preparacion, su aplicacion como medicamentos, composiciones farmaceuticas y nueva utilizacion.
TW349099B (en)	1999-01-01	Apovincamine derivatives and the pharmaceutical composition thereof

Legal Events

Date	Code	Title	Description
2017-09-11	MK1K	Patent expired