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NO980129L - Heterocyklylkarboksamid-derivater og deres anvendelse som terapautiske midler - Google Patents

Heterocyklylkarboksamid-derivater og deres anvendelse som terapautiske midler

Info

Publication number
NO980129L
NO980129L NO980129A NO980129A NO980129L NO 980129 L NO980129 L NO 980129L NO 980129 A NO980129 A NO 980129A NO 980129 A NO980129 A NO 980129A NO 980129 L NO980129 L NO 980129L
Authority
NO
Norway
Prior art keywords
disorders
hyperglycaemia
methylene
disease
therapeutic agents
Prior art date
Application number
NO980129A
Other languages
English (en)
Other versions
NO980129D0 (no
Inventor
Alan Martin Birch
David John Heal
Frank Kerrigan
Keith Frank Martin
Patricia Lesley Needham
Bruce Jeremy Sargent
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of NO980129L publication Critical patent/NO980129L/no
Publication of NO980129D0 publication Critical patent/NO980129D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Forbindelser med formel l u¿Q¿T og deres farmasøytisk akseptable salter hvor A er metylen eller O; B er metylen eller O; g er 0,1, 2, 3 eller 4; R er en eventuell substituent; U er en alkylenkjede eventuelt substituert med en eller flere alkylgupper, Q representerer en divalent gruppe inneholdende nitrogenatomer; og T representerer CO.HET, som kan brukes ved behandlingen av lidelser og sykdommer i det sentrale nervesystemet, for eksempel depresjon, nervøsitet, psykoser, (for eksempel schizofreni), tardiv dyskinese, Parkinsons sykdom, overvekt, hypertensjon, Tourettes syndrom, impotent, medikamentavhengighet, medikamentmisbruk, kognitive lidelser, Alzheimers sykdom, senil dementia, tvangsforestillinger, panikkanfall, sosiale fobierf-spiseforstyrrelser og anoreksia, kardiovaskulære og cerebrovaskulære lidelser, ikke-insulin avhengig sukkersyke, hyperglykemi, forstoppelse, arrytmi, lidelser i det nevroendokrine system, stress eller prostatisk hypertrofi og kramper.
NO980129A 1995-07-13 1998-01-12 Heterocyklylkarboksamid-derivater og deres anvendelse som terapautiske midler NO980129D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514380.6A GB9514380D0 (en) 1995-07-13 1995-07-13 Therapeutic agents
PCT/EP1996/002890 WO1997003071A1 (en) 1995-07-13 1996-07-02 Heterocyclylcarboxamide derivatives and their use as therapeutic agents

Publications (2)

Publication Number Publication Date
NO980129L true NO980129L (no) 1998-01-12
NO980129D0 NO980129D0 (no) 1998-01-12

Family

ID=10777626

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980129A NO980129D0 (no) 1995-07-13 1998-01-12 Heterocyklylkarboksamid-derivater og deres anvendelse som terapautiske midler

Country Status (26)

Country Link
US (1) US5935973A (no)
EP (1) EP0839145B1 (no)
JP (1) JPH11508599A (no)
KR (1) KR19990028918A (no)
CN (1) CN1071755C (no)
AT (1) ATE253573T1 (no)
AU (1) AU708890B2 (no)
BG (1) BG62771B1 (no)
BR (1) BR9609506A (no)
CA (1) CA2223472A1 (no)
CZ (1) CZ388497A3 (no)
DE (1) DE69630604T2 (no)
GB (1) GB9514380D0 (no)
HR (1) HRP960348A2 (no)
HU (1) HUP9901485A3 (no)
IL (1) IL122540A (no)
MX (1) MX9800084A (no)
NO (1) NO980129D0 (no)
NZ (1) NZ313164A (no)
PL (1) PL324529A1 (no)
RU (1) RU2169147C2 (no)
SK (1) SK2498A3 (no)
TR (1) TR199800041T1 (no)
TW (1) TW454006B (no)
WO (1) WO1997003071A1 (no)
ZA (1) ZA965921B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9811879D0 (en) * 1998-06-03 1998-07-29 Knoll Ag Therapeutic agents
GB9915616D0 (en) * 1999-07-05 1999-09-01 Knoll Ag Therapeutic agents
UA73981C2 (en) 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
AU4890301A (en) * 2000-04-17 2001-10-30 Dong Wha Pharmaceutical Industrial Co., Ltd. 6-methylnicotinamide derivatives as antiviral agents
CZ20031434A3 (cs) * 2000-11-14 2003-09-17 Merck Patent Gmbh Použití kombinovaných selektivních dopamin D2 receptorových antagonistů a 5-HT1A receptorových agonistů
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
US8106074B2 (en) 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence
WO2003009835A2 (en) * 2001-07-26 2003-02-06 Merck Patent Gmbh Novel use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts
BRPI0412259B1 (pt) 2003-07-22 2019-08-20 Astex Therapeutics Limited Compostos de 1H-pirazol 3,4-dissubstituídos como moduladores de quinases dependentes de ciclina (CDK), seus usos, processo para a preparação dos mesmos e composição farmacêutica
CA2556589A1 (en) * 2004-02-24 2005-09-01 Bioaxone Therapeutique Inc. 4-substituted piperidine derivatives
JP4604583B2 (ja) * 2004-07-20 2011-01-05 ダイソー株式会社 １−アミド−３−（２−ヒドロキシフェノキシ）−２−プロパノール誘導体、ならびに２−アミドメチル−１，４−ベンゾジオキサン誘導体の製造法
JP5475234B2 (ja) 2005-01-21 2014-04-16 アステックス・セラピューティクス・リミテッド 医薬化合物
AU2006207325B2 (en) 2005-01-21 2012-08-16 Astex Therapeutics Limited Pharmaceutical compounds
TWI457122B (zh) * 2007-07-20 2014-10-21 Orion Corp 作為用於治療周邊和中央神經系統疾病之alpha2C拮抗劑的2,3－二氫苯並[1,4]戴奧辛－2－基甲基衍生物
JP5514804B2 (ja) * 2008-04-29 2014-06-04 エヌエスエイビー、フィリアル アヴ ノイロサーチ スウェーデン エービー、スヴェーリエ ドーパミン神経伝達のモジュレーター
NZ703632A (en) * 2012-06-11 2016-01-29 Bristol Myers Squibb Co Phosphoramidic acid prodrugs of 5-[5-phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridine-3-sulfonamide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8302622D0 (en) * 1983-01-31 1983-03-02 Celltech Ltd Immunoassay
EP0200960A1 (en) * 1985-05-08 1986-11-12 Abbott Laboratories Total estriol fluorescence polarization immunoassay
CA2075057A1 (en) * 1990-03-15 1991-09-16 Pharmacia & Upjohn Company Llc Therapeutically useful heterocyclic indole compounds
US5240943A (en) * 1991-12-19 1993-08-31 G. D. Searle & Co. Benzopyran class iii antiarrhythmic agents
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
GB9318431D0 (en) * 1993-09-06 1993-10-20 Boots Co Plc Therapeutic agents
FR2724383B1 (fr) * 1994-09-13 1996-10-18 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
RU2169147C2 (ru) 2001-06-20
ATE253573T1 (de) 2003-11-15
KR19990028918A (ko) 1999-04-15
AU6517296A (en) 1997-02-10
TR199800041T1 (xx) 1998-05-21
TW454006B (en) 2001-09-11
HUP9901485A3 (en) 2001-03-28
DE69630604D1 (de) 2003-12-11
GB9514380D0 (en) 1995-09-13
EP0839145A1 (en) 1998-05-06
MX9800084A (es) 1998-03-29
EP0839145B1 (en) 2003-11-05
NO980129D0 (no) 1998-01-12
ZA965921B (en) 1998-01-12
AU708890B2 (en) 1999-08-12
BG62771B1 (bg) 2000-07-31
HUP9901485A2 (en) 2000-07-28
BR9609506A (pt) 1999-06-01
JPH11508599A (ja) 1999-07-27
DE69630604T2 (de) 2004-09-23
CN1071755C (zh) 2001-09-26
CZ388497A3 (cs) 1998-06-17
NZ313164A (en) 1999-07-29
BG102145A (en) 1998-11-30
PL324529A1 (en) 1998-06-08
HRP960348A2 (en) 1998-04-30
CN1190967A (zh) 1998-08-19
IL122540A0 (en) 1998-06-15
CA2223472A1 (en) 1997-01-30
SK2498A3 (en) 1998-09-09
WO1997003071A1 (en) 1997-01-30
US5935973A (en) 1999-08-10
IL122540A (en) 2001-10-31

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